AR071728A1 - Terapia con intervalos para el tratamiento del tinnitus - Google Patents
Terapia con intervalos para el tratamiento del tinnitusInfo
- Publication number
- AR071728A1 AR071728A1 ARP080103938A ARP080103938A AR071728A1 AR 071728 A1 AR071728 A1 AR 071728A1 AR P080103938 A ARP080103938 A AR P080103938A AR P080103938 A ARP080103938 A AR P080103938A AR 071728 A1 AR071728 A1 AR 071728A1
- Authority
- AR
- Argentina
- Prior art keywords
- amino
- tinnitus
- dose
- period
- administered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Percussion Or Vibration Massage (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Reivindicacion 1: Un derivado de 1-amino-alquilciclohexano para el tratamiento del tinnitus, caracterizado porque se administra una cantidad eficaz para el uso terapeutico del derivado de 1-amino-alquilciclohexano diariamente por un primer per¡odo de al menos tres (3) meses, a lo que sigue un segundo per¡odo de al menos un (1) mes, donde el derivado de 1-amino-alquilciclohexano se administra en una dosis que es 0-75% de la dosis con eficacia terapeutica. Reivindicacion 2: Uso de un derivado de 1-amino-alquilciclohexano caracterizado porque es para la fabricacion de un medicamento para tratar el tinnitus en un sujeto que lo necesita, donde se administra una cantidad eficaz para el uso terapeutico del derivado de 1-amino-alquilciclohexano diariamente por un primer per¡odo de al menos tres (3) meses, a lo que sigue un segundo per¡odo de al menos un (1) mes, donde el derivado de 1-amino-alquilciclohexano se administra en una dosis de 0-75% de la dosis con eficacia terapeutica.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99339607P | 2007-09-12 | 2007-09-12 | |
EP07253630 | 2007-09-12 | ||
US6693108P | 2008-02-25 | 2008-02-25 | |
US6708308P | 2008-02-25 | 2008-02-25 | |
US6702608P | 2008-02-25 | 2008-02-25 | |
EP08004777 | 2008-03-14 | ||
EP08004776 | 2008-03-14 | ||
EP08004778 | 2008-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR071728A1 true AR071728A1 (es) | 2010-07-14 |
Family
ID=40451596
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080103938A AR071728A1 (es) | 2007-09-12 | 2008-09-10 | Terapia con intervalos para el tratamiento del tinnitus |
ARP080103936A AR070025A1 (es) | 2007-09-12 | 2008-09-10 | Uso de derivados de 1-amino-alquilciclohexano para el tratamiento del tinnitus coclear y composicion farmaceutica |
ARP080103937A AR070026A1 (es) | 2007-09-12 | 2008-09-10 | Conjunto de elementos para la dosificacion de 1-amino-alquilciclohexanos, tal como neramexano, y tratamiento de diversas enfermedades incluyendo el tinnitus |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP080103936A AR070025A1 (es) | 2007-09-12 | 2008-09-10 | Uso de derivados de 1-amino-alquilciclohexano para el tratamiento del tinnitus coclear y composicion farmaceutica |
ARP080103937A AR070026A1 (es) | 2007-09-12 | 2008-09-10 | Conjunto de elementos para la dosificacion de 1-amino-alquilciclohexanos, tal como neramexano, y tratamiento de diversas enfermedades incluyendo el tinnitus |
Country Status (21)
Country | Link |
---|---|
US (6) | US9498450B2 (es) |
EP (6) | EP2386299B1 (es) |
JP (6) | JP5563461B2 (es) |
KR (4) | KR20100052556A (es) |
CN (4) | CN101801365A (es) |
AR (3) | AR071728A1 (es) |
AT (1) | ATE532507T1 (es) |
AU (4) | AU2008298015B2 (es) |
BR (2) | BRPI0816712A2 (es) |
CA (4) | CA2699209A1 (es) |
DK (1) | DK2200600T3 (es) |
ES (5) | ES2596262T3 (es) |
HR (1) | HRP20120046T1 (es) |
MX (4) | MX2010002735A (es) |
PL (1) | PL2200600T3 (es) |
PT (1) | PT2200600E (es) |
RU (1) | RU2011137131A (es) |
SI (1) | SI2200600T1 (es) |
TW (3) | TW200927087A (es) |
WO (4) | WO2009033651A1 (es) |
ZA (4) | ZA201001262B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101801365A (zh) * | 2007-09-12 | 2010-08-11 | 莫茨药物股份两合公司 | 治疗耳鸣的间隔疗法 |
US20110294890A1 (en) | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
US8980318B2 (en) | 2010-06-24 | 2015-03-17 | Merz Pharma Gmbh & Co. Kgaa | Neramexane multiple unit dosage form |
JP6084931B2 (ja) * | 2011-01-20 | 2017-02-22 | メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト アウフ アクティーン | ストレス又は急性聴力損失に関連する耳鳴の治療又は予防のためのネラメキサン |
IL281376B (en) * | 2013-03-06 | 2022-08-01 | Acorda Therapeutics Inc | Medicinal peptides of neuregulin for the treatment or prevention of heart failure |
KR20160143846A (ko) * | 2014-04-28 | 2016-12-14 | 교린 세이야꾸 가부시키 가이샤 | 이명 환자의 치료용 약제 |
KR20160146872A (ko) * | 2014-04-28 | 2016-12-21 | 교린 세이야꾸 가부시키 가이샤 | 이명 환자의 치료용 약제 |
CA2999467C (en) | 2014-10-23 | 2023-10-10 | Arena Pharmaceuticals, Inc. | Method of treating conditions related to the pgi2 receptor |
HUE056138T2 (hu) * | 2015-05-18 | 2022-01-28 | Sensorion | Azasetron a halláskárosodás kezelésében való felhasználásra |
KR101893604B1 (ko) | 2015-08-27 | 2018-08-30 | 경희대학교 산학협력단 | 칸디다 유틸리스 추출물을 포함하는 난청의 예방 또는 치료용 조성물 |
CN105924362B (zh) * | 2016-02-05 | 2018-08-17 | 上海龙翔生物医药开发有限公司 | 芳香环丙基胺类化合物、其药学上可接受的盐、其制备方法及其用途 |
WO2018160882A1 (en) | 2017-03-01 | 2018-09-07 | Arena Pharmaceuticals, Inc. | Compositions comprising pgi2-receptor agonists and processes for the preparation thereof |
KR102268893B1 (ko) | 2020-01-16 | 2021-06-24 | 경북대학교 산학협력단 | 림노트릭스 속 knua002 균주를 포함하는 난청의 예방 또는 치료용 조성물 |
CN111477199B (zh) * | 2020-04-02 | 2021-11-30 | 北京瑞迪欧文化传播有限责任公司 | 一种嵌入式音乐控制系统 |
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US4849222A (en) | 1987-03-24 | 1989-07-18 | The Procter & Gamble Company | Mixtures for treating hypercholesterolemia |
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US5288502A (en) | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
AU7980794A (en) | 1993-10-22 | 1995-05-08 | Genentech Inc. | Methods and compositions for microencapsulation of antigens for use as vaccines |
DE19528388A1 (de) * | 1995-08-02 | 1997-02-06 | Hans Peter Prof Dr Med Zenner | Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs |
WO1998010757A2 (en) | 1996-09-11 | 1998-03-19 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | The use of functional n-methyl-d-aspartate antagonists to ameliorate or prevent aminoglycoside-induced ototoxicity |
TW593225B (en) * | 1997-06-30 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane NMDA receptor antagonists |
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CZ20023479A3 (cs) * | 2000-04-26 | 2003-04-16 | Warner-Lambert Company | Cyklohexylaminový derivát, jako subtyp selektivních antagonistů NMDA receptoru |
DE10048969A1 (de) * | 2000-08-23 | 2002-03-14 | Mueller Schwefe Gerhard | Verwendung von Flupirtin zur Tinnitusbehandlung |
US20030236288A1 (en) * | 2002-02-28 | 2003-12-25 | Karl Schoenafinger | Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase |
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CN1896729A (zh) | 2005-07-15 | 2007-01-17 | 复旦大学附属中山医院 | 纳米药物自组装双稳态量子线阵列及其制备方法 |
US20070141148A1 (en) * | 2005-11-30 | 2007-06-21 | Merz Pharma Gmbh & Co. Kgaa | Neramexane MR matrix tablet |
TW200819458A (en) * | 2006-06-23 | 2008-05-01 | Merz Pharma Gmbh & Co Kgaa | Metabotropic glutamate receptor modulators |
CN101801365A (zh) * | 2007-09-12 | 2010-08-11 | 莫茨药物股份两合公司 | 治疗耳鸣的间隔疗法 |
TW201010691A (en) * | 2008-06-12 | 2010-03-16 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders |
TW201006463A (en) * | 2008-06-26 | 2010-02-16 | Merz Pharma Gmbh & Co Kgaa | Pharmaceutical compositions comprising aminocyclohexane derivatives |
WO2010028769A1 (en) * | 2008-09-10 | 2010-03-18 | Merz Pharma Gmbh & Co. Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of cognitive impairment in tinnitus |
US20110294890A1 (en) * | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
JP6084931B2 (ja) * | 2011-01-20 | 2017-02-22 | メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト アウフ アクティーン | ストレス又は急性聴力損失に関連する耳鳴の治療又は予防のためのネラメキサン |
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2008
- 2008-09-10 CN CN200880106925A patent/CN101801365A/zh active Pending
- 2008-09-10 WO PCT/EP2008/007420 patent/WO2009033651A1/en active Application Filing
- 2008-09-10 JP JP2010524395A patent/JP5563461B2/ja not_active Expired - Fee Related
- 2008-09-10 AR ARP080103938A patent/AR071728A1/es not_active Application Discontinuation
- 2008-09-10 PL PL08801987T patent/PL2200600T3/pl unknown
- 2008-09-10 TW TW097134701A patent/TW200927087A/zh unknown
- 2008-09-10 ES ES11005567.0T patent/ES2596262T3/es active Active
- 2008-09-10 MX MX2010002735A patent/MX2010002735A/es unknown
- 2008-09-10 US US12/733,646 patent/US9498450B2/en not_active Expired - Fee Related
- 2008-09-10 US US12/733,582 patent/US9468610B2/en not_active Expired - Fee Related
- 2008-09-10 CN CN200880106404A patent/CN101835469A/zh active Pending
- 2008-09-10 CA CA2699209A patent/CA2699209A1/en not_active Abandoned
- 2008-09-10 BR BRPI0816712A patent/BRPI0816712A2/pt not_active IP Right Cessation
- 2008-09-10 MX MX2010002734A patent/MX2010002734A/es not_active Application Discontinuation
- 2008-09-10 ES ES12006826.7T patent/ES2562709T3/es active Active
- 2008-09-10 TW TW097134705A patent/TW200922544A/zh unknown
- 2008-09-10 EP EP11005567.0A patent/EP2386299B1/en active Active
- 2008-09-10 ES ES08801987T patent/ES2377253T3/es active Active
- 2008-09-10 AU AU2008298015A patent/AU2008298015B2/en not_active Ceased
- 2008-09-10 JP JP2010524394A patent/JP5563460B2/ja not_active Expired - Fee Related
- 2008-09-10 AU AU2008298017A patent/AU2008298017B2/en not_active Ceased
- 2008-09-10 KR KR1020107007786A patent/KR20100052556A/ko not_active Application Discontinuation
- 2008-09-10 ES ES08801986.4T patent/ES2510565T3/es active Active
- 2008-09-10 EP EP08801985.6A patent/EP2200599B1/en active Active
- 2008-09-10 CN CN200880106973A patent/CN101801366A/zh active Pending
- 2008-09-10 WO PCT/EP2008/007421 patent/WO2009033652A1/en active Application Filing
- 2008-09-10 ES ES08801985.6T patent/ES2604945T3/es active Active
- 2008-09-10 AU AU2008298018A patent/AU2008298018C1/en not_active Ceased
- 2008-09-10 CA CA2699207A patent/CA2699207A1/en not_active Abandoned
- 2008-09-10 CA CA2699210A patent/CA2699210A1/en not_active Abandoned
- 2008-09-10 CA CA2699213A patent/CA2699213A1/en not_active Abandoned
- 2008-09-10 SI SI200830530T patent/SI2200600T1/sl unknown
- 2008-09-10 AU AU2008298016A patent/AU2008298016B2/en not_active Ceased
- 2008-09-10 JP JP2010524393A patent/JP5612473B2/ja not_active Expired - Fee Related
- 2008-09-10 WO PCT/EP2008/007419 patent/WO2009033650A1/en active Application Filing
- 2008-09-10 EP EP12006826.7A patent/EP2548552B1/en active Active
- 2008-09-10 KR KR1020107007787A patent/KR20100052557A/ko not_active Application Discontinuation
- 2008-09-10 BR BRPI0816690A patent/BRPI0816690A2/pt not_active IP Right Cessation
- 2008-09-10 MX MX2010002736A patent/MX2010002736A/es not_active Application Discontinuation
- 2008-09-10 MX MX2010002733A patent/MX2010002733A/es not_active Application Discontinuation
- 2008-09-10 DK DK08801987.2T patent/DK2200600T3/da active
- 2008-09-10 CN CN200880106975A patent/CN101795679A/zh active Pending
- 2008-09-10 KR KR1020107007793A patent/KR20100052558A/ko not_active Application Discontinuation
- 2008-09-10 AT AT08801987T patent/ATE532507T1/de active
- 2008-09-10 EP EP08801986.4A patent/EP2203163B1/en active Active
- 2008-09-10 US US12/733,577 patent/US20110086916A1/en not_active Abandoned
- 2008-09-10 PT PT08801987T patent/PT2200600E/pt unknown
- 2008-09-10 WO PCT/EP2008/007418 patent/WO2009033649A1/en active Application Filing
- 2008-09-10 AR ARP080103936A patent/AR070025A1/es not_active Application Discontinuation
- 2008-09-10 JP JP2010524392A patent/JP5613053B2/ja not_active Expired - Fee Related
- 2008-09-10 EP EP08801984A patent/EP2200598A1/en not_active Withdrawn
- 2008-09-10 EP EP08801987A patent/EP2200600B1/en active Active
- 2008-09-10 AR ARP080103937A patent/AR070026A1/es not_active Application Discontinuation
- 2008-09-10 KR KR1020107007795A patent/KR20100052559A/ko not_active Application Discontinuation
- 2008-09-10 US US12/733,645 patent/US8877814B2/en not_active Expired - Fee Related
- 2008-09-10 TW TW097134699A patent/TW200918042A/zh unknown
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2010
- 2010-02-22 ZA ZA2010/01262A patent/ZA201001262B/en unknown
- 2010-02-22 ZA ZA2010/01264A patent/ZA201001264B/en unknown
- 2010-02-22 ZA ZA2010/01263A patent/ZA201001263B/en unknown
- 2010-02-22 ZA ZA2010/01261A patent/ZA201001261B/en unknown
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2011
- 2011-09-08 RU RU2011137131/15A patent/RU2011137131A/ru not_active Application Discontinuation
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2012
- 2012-01-16 HR HR20120046T patent/HRP20120046T1/hr unknown
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2014
- 2014-06-12 JP JP2014121268A patent/JP5784188B2/ja not_active Expired - Fee Related
- 2014-06-12 JP JP2014121269A patent/JP5784189B2/ja not_active Expired - Fee Related
- 2014-09-30 US US14/501,438 patent/US20150018425A1/en not_active Abandoned
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2016
- 2016-10-12 US US15/291,527 patent/US20170027885A1/en not_active Abandoned
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