AR089862A1 - USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA - Google Patents
USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEAInfo
- Publication number
- AR089862A1 AR089862A1 ARP130100296A ARP130100296A AR089862A1 AR 089862 A1 AR089862 A1 AR 089862A1 AR P130100296 A ARP130100296 A AR P130100296A AR P130100296 A ARP130100296 A AR P130100296A AR 089862 A1 AR089862 A1 AR 089862A1
- Authority
- AR
- Argentina
- Prior art keywords
- laquinimod
- crohn
- disease
- thumor
- tnfa
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Abstract
Reivindicación 45: Una composición farmacéutica, caracterizada porque comprende una dosis unitaria menor que 0,5 mg de laquinimod para inducir o mantener la remisión clínica en un paciente humano que sufre de la enfermedad de Crohn.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261595006P | 2012-02-03 | 2012-02-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR089862A1 true AR089862A1 (es) | 2014-09-24 |
Family
ID=48903432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130100296A AR089862A1 (es) | 2012-02-03 | 2013-02-01 | USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA |
Country Status (16)
Country | Link |
---|---|
US (3) | US9161935B2 (es) |
EP (1) | EP2811832A4 (es) |
JP (2) | JP2015505564A (es) |
KR (1) | KR20140138694A (es) |
CN (2) | CN106063787A (es) |
AR (1) | AR089862A1 (es) |
AU (2) | AU2013214909A1 (es) |
BR (1) | BR112014018485A8 (es) |
CA (1) | CA2862865A1 (es) |
EA (1) | EA201491460A1 (es) |
HK (1) | HK1202776A1 (es) |
IL (1) | IL233557A0 (es) |
MX (1) | MX2014009373A (es) |
SG (1) | SG11201404214QA (es) |
TW (1) | TW201345527A (es) |
WO (1) | WO2013116657A1 (es) |
Families Citing this family (15)
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PT2234485E (pt) | 2007-12-20 | 2014-02-17 | Teva Pharma | Preparações de laquinimod estáveis |
CA2786994C (en) | 2010-01-27 | 2018-01-16 | Arena Pharmaceuticals, Inc. | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
MX2014004420A (es) | 2011-10-12 | 2014-07-09 | Teva Pharma | Tratamiento de esclerosis multiple con combinacion de laquinimod y fingolimod. |
SG11201404419WA (en) | 2012-02-16 | 2014-10-30 | Teva Pharma | N-ethyl-n-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinoline carboxamide, preparation and uses thereof |
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TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
EA201590788A1 (ru) | 2012-11-07 | 2015-12-30 | Тева Фармасьютикал Индастриз Лтд. | Аминные соли лахинимода |
NZ630427A (en) | 2013-03-14 | 2017-06-30 | Teva Pharma | Crystals of laquinimod sodium and improved process for the manufacture thereof |
EP3094330A4 (en) * | 2014-01-17 | 2017-09-27 | Teva Pharmaceutical Industries Ltd | Treatment of crohn's disease using low doses of laquinimod |
EA201692180A1 (ru) | 2014-04-29 | 2017-08-31 | Тева Фармасьютикал Индастриз Лтд. | Лахинимод для лечения пациентов с рецидивирующе-ремиттирующим рассеянным склерозом (рррс) с высоким статусом инвалидизации |
MA42807A (fr) | 2015-06-22 | 2018-07-25 | Arena Pharm Inc | Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1 |
RU2018113694A (ru) * | 2015-09-17 | 2019-10-17 | Эмджен Инк. | Прогноз клинического ответа на антагонисты ил-23 с использованием биомаркеров сигнального пути ил-23 |
MX2019009841A (es) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compuestos y metodos para el tratamiento de la colangitis biliar primaria. |
CN110545848A (zh) | 2017-02-16 | 2019-12-06 | 艾尼纳制药公司 | 用于治疗具有肠外表现的炎症性肠病的化合物和方法 |
KR20210098487A (ko) * | 2018-11-30 | 2021-08-10 | 아레나 파마슈티칼스, 인크. | S1p1 수용체와 관련된 병태의 치료 방법 |
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EP2968203A1 (en) | 2013-03-14 | 2016-01-20 | Teva Pharmaceutical Industries Ltd. | Transdermal formulations of laquinimod |
EP3094330A4 (en) * | 2014-01-17 | 2017-09-27 | Teva Pharmaceutical Industries Ltd | Treatment of crohn's disease using low doses of laquinimod |
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2013
- 2013-02-01 AU AU2013214909A patent/AU2013214909A1/en not_active Abandoned
- 2013-02-01 EP EP13744015.2A patent/EP2811832A4/en not_active Withdrawn
- 2013-02-01 JP JP2014555758A patent/JP2015505564A/ja not_active Withdrawn
- 2013-02-01 TW TW102104087A patent/TW201345527A/zh unknown
- 2013-02-01 MX MX2014009373A patent/MX2014009373A/es unknown
- 2013-02-01 BR BR112014018485A patent/BR112014018485A8/pt not_active IP Right Cessation
- 2013-02-01 EA EA201491460A patent/EA201491460A1/ru unknown
- 2013-02-01 AR ARP130100296A patent/AR089862A1/es unknown
- 2013-02-01 SG SG11201404214QA patent/SG11201404214QA/en unknown
- 2013-02-01 KR KR1020147024856A patent/KR20140138694A/ko not_active Application Discontinuation
- 2013-02-01 CN CN201610357641.1A patent/CN106063787A/zh active Pending
- 2013-02-01 WO PCT/US2013/024356 patent/WO2013116657A1/en active Application Filing
- 2013-02-01 US US13/757,004 patent/US9161935B2/en active Active
- 2013-02-01 CN CN201380007766.6A patent/CN104093310A/zh active Pending
- 2013-02-01 CA CA2862865A patent/CA2862865A1/en not_active Abandoned
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2014
- 2014-07-08 IL IL233557A patent/IL233557A0/en unknown
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2015
- 2015-04-10 HK HK15103524.2A patent/HK1202776A1/xx unknown
- 2015-08-25 US US14/835,123 patent/US20150359788A1/en not_active Abandoned
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2017
- 2017-01-24 AU AU2017200472A patent/AU2017200472A1/en not_active Abandoned
- 2017-05-26 JP JP2017104049A patent/JP2017200926A/ja not_active Withdrawn
- 2017-06-26 US US15/633,132 patent/US20170290822A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
TW201345527A (zh) | 2013-11-16 |
JP2015505564A (ja) | 2015-02-23 |
BR112014018485A8 (pt) | 2017-07-11 |
SG11201404214QA (en) | 2014-08-28 |
IL233557A0 (en) | 2014-08-31 |
EA201491460A1 (ru) | 2015-01-30 |
US20150359788A1 (en) | 2015-12-17 |
AU2013214909A1 (en) | 2014-09-18 |
MX2014009373A (es) | 2014-08-27 |
JP2017200926A (ja) | 2017-11-09 |
CN104093310A (zh) | 2014-10-08 |
US9161935B2 (en) | 2015-10-20 |
EP2811832A1 (en) | 2014-12-17 |
HK1202776A1 (en) | 2015-10-09 |
US20130203807A1 (en) | 2013-08-08 |
AU2017200472A1 (en) | 2017-02-09 |
WO2013116657A1 (en) | 2013-08-08 |
US20170290822A1 (en) | 2017-10-12 |
KR20140138694A (ko) | 2014-12-04 |
EP2811832A4 (en) | 2015-09-23 |
CN106063787A (zh) | 2016-11-02 |
CA2862865A1 (en) | 2013-08-08 |
BR112014018485A2 (es) | 2017-06-20 |
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