PE20142319A1 - Tratamiento de esclerosis multiple con combinacion de laquinimod y acetato de glatiramero - Google Patents
Tratamiento de esclerosis multiple con combinacion de laquinimod y acetato de glatirameroInfo
- Publication number
- PE20142319A1 PE20142319A1 PE2014000132A PE2014000132A PE20142319A1 PE 20142319 A1 PE20142319 A1 PE 20142319A1 PE 2014000132 A PE2014000132 A PE 2014000132A PE 2014000132 A PE2014000132 A PE 2014000132A PE 20142319 A1 PE20142319 A1 PE 20142319A1
- Authority
- PE
- Peru
- Prior art keywords
- laquinimod
- multiple sclerosis
- combination
- glatiramer acetate
- daily
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A61K9/0043—Nose
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- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract
REFERIDA A UN METODO PARA TRATAR UN PACIENTE HUMANO AFECTADO CON ESCLEROSIS MULTIPLE O QUE PRESENTA UN SINDROME CLINICAMENTE AISLADO QUE COMPRENDE ADMINISTRAR ORALMENTE AL PACIENTE UNA DOSIS DIARIA DE LAQUINIMOD E INYECTAR SUBCUTANEAMENTE UNA DOSIS DIARIA DE 20 MG DE ACETATO DE GLATIRAMERO, DE PREFERENCIA EL LAQUINIMOD ES LAQUINIMOD SODICO. TAMBIEN ESTA REFERIDA A UNA COMPOSICION FARMACEUTICA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161512808P | 2011-07-28 | 2011-07-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20142319A1 true PE20142319A1 (es) | 2015-01-24 |
Family
ID=47597714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2014000132A PE20142319A1 (es) | 2011-07-28 | 2012-07-27 | Tratamiento de esclerosis multiple con combinacion de laquinimod y acetato de glatiramero |
Country Status (19)
Country | Link |
---|---|
US (3) | US20130029916A1 (es) |
EP (1) | EP2736335A4 (es) |
JP (2) | JP2014521658A (es) |
KR (1) | KR20140054166A (es) |
CN (2) | CN105944081A (es) |
AU (2) | AU2012286699A1 (es) |
BR (1) | BR112014002095A2 (es) |
CA (1) | CA2843433A1 (es) |
CL (2) | CL2014000209A1 (es) |
EA (1) | EA201490377A1 (es) |
HK (2) | HK1198279A1 (es) |
IL (1) | IL251397A0 (es) |
IN (1) | IN2014MN00333A (es) |
MX (1) | MX2014001050A (es) |
PE (1) | PE20142319A1 (es) |
SG (1) | SG10201606191PA (es) |
UY (1) | UY34358A (es) |
WO (1) | WO2013016684A1 (es) |
ZA (1) | ZA201401371B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2682120T (pt) | 2007-12-20 | 2016-11-07 | Teva Pharma | Preparações de laquinimod estáveis |
SG183512A1 (en) * | 2010-03-03 | 2012-09-27 | Teva Pharma | Treatment of lupus nephritis using laquinimod |
AU2011223697B2 (en) | 2010-03-03 | 2016-07-14 | Teva Pharmaceutical Industries Ltd. | Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate |
US8889627B2 (en) | 2011-10-12 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
AR089862A1 (es) | 2012-02-03 | 2014-09-24 | Teva Pharma | USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA |
CA2863409A1 (en) | 2012-02-16 | 2013-08-22 | Teva Pharmaceutical Industries Ltd. | N-ethyl-n-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinolinecarboxamide, preparation and uses thereof |
TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
MX2015005632A (es) | 2012-11-07 | 2016-02-05 | Teva Pharma | Sales de amina de laquinimod. |
JP2016514162A (ja) | 2013-03-14 | 2016-05-19 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドナトリウムの結晶およびその製造のための改善された方法 |
US20160201132A1 (en) * | 2013-09-12 | 2016-07-14 | Teva Pharmaceutical Industries Ltd. | Gene expression biomarkers of laquinimod responsiveness |
AR097792A1 (es) * | 2013-09-27 | 2016-04-13 | Teva Pharma | Terapia combinada con laquinimod para el tratamiento de la esclerosis múltiple |
CA2930113A1 (en) * | 2013-11-15 | 2015-05-21 | Teva Pharmaceutical Industries Ltd. | Treatment of glaucoma using laquinimod |
WO2015109083A1 (en) * | 2014-01-17 | 2015-07-23 | Teva Pharmaceutical Industries Ltd. | Treatment of crohn's disease using low doses of laquinimod |
EA201692180A1 (ru) | 2014-04-29 | 2017-08-31 | Тева Фармасьютикал Индастриз Лтд. | Лахинимод для лечения пациентов с рецидивирующе-ремиттирующим рассеянным склерозом (рррс) с высоким статусом инвалидизации |
US20150361757A1 (en) * | 2014-06-17 | 2015-12-17 | Baker Hughes Incoporated | Borehole shut-in system with pressure interrogation for non-penetrated borehole barriers |
CA2961187A1 (en) * | 2014-09-16 | 2016-03-24 | Teva Pharmaceuticals Industries Ltd. | Treatment of neurodegenerative diseases with combination of laquinimod and fingolimod |
WO2017019862A1 (en) * | 2015-07-30 | 2017-02-02 | Teva Pharmaceuticals Industries Ltd. | Combination formulation of laquinimod and glatiramer acetate with amino acids |
SG11202010087UA (en) * | 2018-04-13 | 2020-11-27 | Mordechai Chevion | Compositions and methods for treatment of demyelination |
JP2023509336A (ja) | 2019-12-19 | 2023-03-08 | アクティブ バイオテック エービー | 過剰血管新生に関連する眼疾患を治療する化合物 |
KR102350943B1 (ko) * | 2021-07-12 | 2022-01-14 | 주식회사 바움디자인시스템즈 | 집적 회로에 대한 소비 전력을 예측하는 방법 및 이를 수행하는 소비 전력 예측 시스템 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002076503A1 (en) * | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
EP1778286A4 (en) * | 2004-03-03 | 2009-04-08 | Teva Pharma | COMBINATION THERAPY WITH ACETATE OF GLATIRAMER AND RILUZOLE |
DK2035001T3 (da) * | 2006-06-12 | 2012-02-27 | Teva Pharma | Stabile laquinimod-tilberedninger |
ES2329327B1 (es) * | 2008-03-19 | 2010-09-17 | Proyecto De Biomedicina Cima, S.L. | Combinaciones sinergicas de 5'-metiltioadenosina. |
CN104311486A (zh) * | 2008-09-03 | 2015-01-28 | 泰华制药工业有限公司 | 2-羰基-1,2-二氢喹啉免疫功能调节剂 |
AR073295A1 (es) * | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
EP2376456A2 (en) * | 2008-12-17 | 2011-10-19 | Actavis Group Ptc Ehf | Highly pure laquinimod or a pharmaceutically acceptable salt thereof |
HUE026406T2 (en) * | 2009-06-19 | 2016-06-28 | Teva Pharma | Treatment of multiple sclerosis with laquinimod |
ME02495B (me) * | 2009-08-10 | 2017-02-20 | Teva Pharma | Tretman poremećaja koji su u vezi sa bdnf primenom lakvinimoda |
CA2775599A1 (en) * | 2009-10-27 | 2011-05-12 | Wyeth Llc | Bazedoxifene formulations with antioxidants |
US20130035390A1 (en) * | 2010-01-13 | 2013-02-07 | Ramot At Tel-Aviv University Ltd. | Treatment of multiple sclerosis |
-
2012
- 2012-07-27 JP JP2014523092A patent/JP2014521658A/ja not_active Withdrawn
- 2012-07-27 AU AU2012286699A patent/AU2012286699A1/en not_active Abandoned
- 2012-07-27 CN CN201610302142.2A patent/CN105944081A/zh active Pending
- 2012-07-27 SG SG10201606191PA patent/SG10201606191PA/en unknown
- 2012-07-27 US US13/560,851 patent/US20130029916A1/en not_active Abandoned
- 2012-07-27 WO PCT/US2012/048684 patent/WO2013016684A1/en active Application Filing
- 2012-07-27 PE PE2014000132A patent/PE20142319A1/es not_active Application Discontinuation
- 2012-07-27 EP EP12817089.1A patent/EP2736335A4/en not_active Withdrawn
- 2012-07-27 KR KR1020147005638A patent/KR20140054166A/ko not_active Application Discontinuation
- 2012-07-27 MX MX2014001050A patent/MX2014001050A/es unknown
- 2012-07-27 CA CA2843433A patent/CA2843433A1/en not_active Abandoned
- 2012-07-27 BR BR112014002095A patent/BR112014002095A2/pt not_active IP Right Cessation
- 2012-07-27 EA EA201490377A patent/EA201490377A1/ru unknown
- 2012-07-27 CN CN201280043755.9A patent/CN103781354A/zh active Pending
- 2012-07-27 IN IN333MUN2014 patent/IN2014MN00333A/en unknown
- 2012-10-01 UY UY0001034358A patent/UY34358A/es not_active Application Discontinuation
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2014
- 2014-01-28 CL CL2014000209A patent/CL2014000209A1/es unknown
- 2014-02-21 ZA ZA2014/01371A patent/ZA201401371B/en unknown
- 2014-11-21 HK HK14111812.7A patent/HK1198279A1/xx unknown
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2015
- 2015-07-16 US US14/801,595 patent/US20160038532A1/en not_active Abandoned
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2016
- 2016-05-06 US US15/148,074 patent/US20160361352A1/en not_active Abandoned
- 2016-07-11 AU AU2016204777A patent/AU2016204777A1/en not_active Abandoned
- 2016-08-24 CL CL2016002132A patent/CL2016002132A1/es unknown
- 2016-11-29 JP JP2016230818A patent/JP2017081930A/ja not_active Withdrawn
- 2016-12-22 HK HK16114575A patent/HK1226940A1/zh unknown
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2017
- 2017-03-27 IL IL251397A patent/IL251397A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20160038532A1 (en) | 2016-02-11 |
CL2014000209A1 (es) | 2014-08-22 |
HK1226940A1 (zh) | 2017-10-13 |
US20160361352A1 (en) | 2016-12-15 |
JP2014521658A (ja) | 2014-08-28 |
US20130029916A1 (en) | 2013-01-31 |
CN103781354A (zh) | 2014-05-07 |
HK1198279A1 (en) | 2015-03-27 |
IN2014MN00333A (es) | 2015-09-25 |
CL2016002132A1 (es) | 2017-06-09 |
AU2016204777A1 (en) | 2016-07-28 |
BR112014002095A2 (pt) | 2017-02-21 |
UY34358A (es) | 2014-02-28 |
CN105944081A (zh) | 2016-09-21 |
AU2012286699A1 (en) | 2014-03-13 |
WO2013016684A1 (en) | 2013-01-31 |
EP2736335A4 (en) | 2015-01-07 |
KR20140054166A (ko) | 2014-05-08 |
IL251397A0 (en) | 2017-05-29 |
EP2736335A1 (en) | 2014-06-04 |
ZA201401371B (en) | 2015-08-26 |
SG10201606191PA (en) | 2016-09-29 |
MX2014001050A (es) | 2014-04-14 |
EA201490377A1 (ru) | 2014-11-28 |
CA2843433A1 (en) | 2013-01-31 |
JP2017081930A (ja) | 2017-05-18 |
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