HK1226940A1 - 用拉喹莫德與醋酸格拉替雷的組合治療多發性硬化症 - Google Patents

用拉喹莫德與醋酸格拉替雷的組合治療多發性硬化症

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Publication number
HK1226940A1
HK1226940A1 HK16114575A HK16114575A HK1226940A1 HK 1226940 A1 HK1226940 A1 HK 1226940A1 HK 16114575 A HK16114575 A HK 16114575A HK 16114575 A HK16114575 A HK 16114575A HK 1226940 A1 HK1226940 A1 HK 1226940A1
Authority
HK
Hong Kong
Prior art keywords
laquinimod
treatment
combination
multiple sclerosis
glatiramer acetate
Prior art date
Application number
HK16114575A
Other languages
English (en)
Inventor
Gilgun Yossi
Tarcic Nora
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of HK1226940A1 publication Critical patent/HK1226940A1/zh

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035Blister-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
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    • A61K31/765Polymers containing oxygen
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61K9/0043Nose
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    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
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    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
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    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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  • Pain & Pain Management (AREA)
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  • Biochemistry (AREA)
  • Physiology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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HK16114575A 2011-07-28 2016-12-22 用拉喹莫德與醋酸格拉替雷的組合治療多發性硬化症 HK1226940A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161512808P 2011-07-28 2011-07-28

Publications (1)

Publication Number Publication Date
HK1226940A1 true HK1226940A1 (zh) 2017-10-13

Family

ID=47597714

Family Applications (2)

Application Number Title Priority Date Filing Date
HK14111812.7A HK1198279A1 (zh) 2011-07-28 2014-11-21 用拉喹莫德與醋酸格拉替雷的組合治療多發性硬化症
HK16114575A HK1226940A1 (zh) 2011-07-28 2016-12-22 用拉喹莫德與醋酸格拉替雷的組合治療多發性硬化症

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HK14111812.7A HK1198279A1 (zh) 2011-07-28 2014-11-21 用拉喹莫德與醋酸格拉替雷的組合治療多發性硬化症

Country Status (19)

Country Link
US (3) US20130029916A1 (zh)
EP (1) EP2736335A4 (zh)
JP (2) JP2014521658A (zh)
KR (1) KR20140054166A (zh)
CN (2) CN105944081A (zh)
AU (2) AU2012286699A1 (zh)
BR (1) BR112014002095A2 (zh)
CA (1) CA2843433A1 (zh)
CL (2) CL2014000209A1 (zh)
EA (1) EA201490377A1 (zh)
HK (2) HK1198279A1 (zh)
IL (1) IL251397A0 (zh)
IN (1) IN2014MN00333A (zh)
MX (1) MX2014001050A (zh)
PE (1) PE20142319A1 (zh)
SG (1) SG10201606191PA (zh)
UY (1) UY34358A (zh)
WO (1) WO2013016684A1 (zh)
ZA (1) ZA201401371B (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2234485T1 (sl) 2007-12-20 2014-03-31 Teva Pharmaceutical Industries Ltd. Stabilni lakvinimodni pripravki
SG183513A1 (en) 2010-03-03 2012-09-27 Teva Pharma Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate
MX337614B (es) * 2010-03-03 2016-03-10 Teva Pharma Tratamiento de lupus nefritis usando laquinimod.
EP2766020A4 (en) 2011-10-12 2015-04-01 Teva Pharma TREATMENT OF MULTIPLE SCLEROSIS BY COMBINING LAQUINIMOD AND FINGOLIMOD
SG11201404214QA (en) 2012-02-03 2014-08-28 Teva Pharma USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY
JP6215238B2 (ja) 2012-02-16 2017-10-18 テバ ファーマシューティカル インダストリーズ リミティド N−エチル−n−フェニル−1,2−ジヒドロ−4,5−ジ−ヒドロキシ−1−メチル−2−オキソ−3−キノリンカルボキサミド、その製剤、および使用
TW201350467A (zh) 2012-05-08 2013-12-16 Teva Pharma N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
TW201410244A (zh) 2012-08-13 2014-03-16 Teva Pharma 用於治療gaba媒介之疾病之拉喹莫德(laquinimod)
CA2890194A1 (en) 2012-11-07 2014-05-15 Teva Pharmaceutical Industries Ltd. Amine salts of laquinimod
US20160046582A1 (en) 2013-03-14 2016-02-18 Teva Pharmaceutical Industries Ltd. Crystals of laquinimod sodium and improved process for the manufacture thereof
WO2015038963A1 (en) * 2013-09-12 2015-03-19 Teva Pharmaceutical Industries, Ltd. Gene expression biomarkers of laquinimod responsiveness
CN105848653A (zh) * 2013-09-27 2016-08-10 梯瓦制药工业有限公司 用于治疗多发性硬化症的拉喹莫德联合治疗
CN105960238A (zh) * 2013-11-15 2016-09-21 梯瓦制药工业有限公司 使用拉喹莫德治疗青光眼
US20160331742A1 (en) * 2014-01-17 2016-11-17 Teva Pharmaceutical Industries, Ltd. Treatment of crohn's disease using low doses of laquinimod
SG11201608674UA (en) 2014-04-29 2016-11-29 Teva Pharma Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status
US20150361757A1 (en) * 2014-06-17 2015-12-17 Baker Hughes Incoporated Borehole shut-in system with pressure interrogation for non-penetrated borehole barriers
EP3193870A4 (en) * 2014-09-16 2018-04-25 Teva Pharmaceutical Industries Ltd. Treatment of neurodegenerative diseases with combination of laquinimod and fingolimod
US20170028013A1 (en) * 2015-07-30 2017-02-02 Teva Pharmaceutical Industries, Ltd. Combination formulation of laquinimod and glatiramer acetate with amino acids
CN112153967A (zh) * 2018-04-13 2020-12-29 莫迪凯·舍维龙 治疗脱髓鞘的组合物和方法
AU2020408179A1 (en) 2019-12-19 2022-06-30 Active Biotech Ab Compounds for treatment of eye diseases associated with excessive vascularisation
KR102350943B1 (ko) * 2021-07-12 2022-01-14 주식회사 바움디자인시스템즈 집적 회로에 대한 소비 전력을 예측하는 방법 및 이를 수행하는 소비 전력 예측 시스템

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002076503A1 (en) * 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
AU2005218625A1 (en) * 2004-03-03 2005-09-15 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and riluzole
DK2035001T3 (da) * 2006-06-12 2012-02-27 Teva Pharma Stabile laquinimod-tilberedninger
ES2329327B1 (es) * 2008-03-19 2010-09-17 Proyecto De Biomedicina Cima, S.L. Combinaciones sinergicas de 5'-metiltioadenosina.
WO2010028015A2 (en) * 2008-09-03 2010-03-11 Auspex Pharmaceuticals, Inc 2-oxo-1,2-dihydro-quinoline modulators of immune function
AR073295A1 (es) * 2008-09-16 2010-10-28 Genentech Inc Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion.
EP2376456A2 (en) * 2008-12-17 2011-10-19 Actavis Group Ptc Ehf Highly pure laquinimod or a pharmaceutically acceptable salt thereof
ES2548999T3 (es) * 2009-06-19 2015-10-22 Teva Pharmaceutical Industries Ltd. Tratamiento de la esclerosis múltiple con laquinimod
AU2010282948C1 (en) * 2009-08-10 2017-03-02 Active Biotech, Ab Treatment of BDNF-related disorders using laquinimod
AR078785A1 (es) * 2009-10-27 2011-11-30 Wyeth Llc Formulaciones de bazedoxifeno con antioxidantes
WO2011086470A1 (en) * 2010-01-13 2011-07-21 Ramot At Tel-Aviv University Ltd Treatment of multiple sclerosis

Also Published As

Publication number Publication date
ZA201401371B (en) 2015-08-26
PE20142319A1 (es) 2015-01-24
MX2014001050A (es) 2014-04-14
BR112014002095A2 (pt) 2017-02-21
JP2014521658A (ja) 2014-08-28
KR20140054166A (ko) 2014-05-08
JP2017081930A (ja) 2017-05-18
WO2013016684A1 (en) 2013-01-31
AU2012286699A1 (en) 2014-03-13
IN2014MN00333A (zh) 2015-09-25
CL2014000209A1 (es) 2014-08-22
HK1198279A1 (zh) 2015-03-27
CL2016002132A1 (es) 2017-06-09
US20160361352A1 (en) 2016-12-15
IL251397A0 (en) 2017-05-29
EP2736335A4 (en) 2015-01-07
EP2736335A1 (en) 2014-06-04
US20160038532A1 (en) 2016-02-11
AU2016204777A1 (en) 2016-07-28
EA201490377A1 (ru) 2014-11-28
CN103781354A (zh) 2014-05-07
US20130029916A1 (en) 2013-01-31
CN105944081A (zh) 2016-09-21
UY34358A (es) 2014-02-28
SG10201606191PA (en) 2016-09-29
CA2843433A1 (en) 2013-01-31

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