AR092177A1 - Metodos para tratar o prevenir asma administrando un antagonista de il-4r - Google Patents

Metodos para tratar o prevenir asma administrando un antagonista de il-4r

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Publication number
AR092177A1
AR092177A1 ARP130102945A ARP130102945A AR092177A1 AR 092177 A1 AR092177 A1 AR 092177A1 AR P130102945 A ARP130102945 A AR P130102945A AR P130102945 A ARP130102945 A AR P130102945A AR 092177 A1 AR092177 A1 AR 092177A1
Authority
AR
Argentina
Prior art keywords
antagonist
methods
treat
asthma
managing
Prior art date
Application number
ARP130102945A
Other languages
English (en)
Original Assignee
Sanofi Sa
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50148186&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR092177(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Sa, Regeneron Pharma filed Critical Sanofi Sa
Publication of AR092177A1 publication Critical patent/AR092177A1/es

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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A—HUMAN NECESSITIES
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/247—IL-4
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/6854—Immunoglobulins
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

Métodos para tratar o prevenir asma y afecciones asociadas en un paciente. Los métodos de la presente comprenden administrar a un sujeto que lo necesite una composición terapéutica que comprende un antagonista del receptor de interleucina-4 (IL-4R), tal como un anticuerpo anti-IL-4R. Reivindicación 108: Un antagonista de IL-4R para su uso en el tratamiento y/o prevención de asma y afecciones relacionadas. Reivindicación 109: Una composición farmacéutica que comprende un antagonista de anticuerpo anti-IL4R o un fragmento de unión a antígeno del mismo para su uso en el tratamiento y/o prevención de asma y afecciones relacionadas.
ARP130102945A 2012-08-21 2013-08-20 Metodos para tratar o prevenir asma administrando un antagonista de il-4r AR092177A1 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261691625P 2012-08-21 2012-08-21
US201361758097P 2013-01-29 2013-01-29
US201361761279P 2013-02-06 2013-02-06
US201361783796P 2013-03-14 2013-03-14
US201361805797P 2013-03-27 2013-03-27
FR1356994 2013-07-16

Publications (1)

Publication Number Publication Date
AR092177A1 true AR092177A1 (es) 2015-03-25

Family

ID=50148186

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130102945A AR092177A1 (es) 2012-08-21 2013-08-20 Metodos para tratar o prevenir asma administrando un antagonista de il-4r

Country Status (27)

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US (2) US9574004B2 (es)
EP (4) EP4011915B8 (es)
JP (3) JP6306588B2 (es)
KR (4) KR20230028592A (es)
CN (2) CN104755495A (es)
AR (1) AR092177A1 (es)
AU (3) AU2013305945B2 (es)
BR (1) BR112015003590A8 (es)
CA (1) CA2882416A1 (es)
DK (1) DK2888281T3 (es)
ES (2) ES2900342T3 (es)
HK (1) HK1211605A1 (es)
HR (1) HRP20181963T1 (es)
IL (2) IL293398A (es)
IN (1) IN2015KN00414A (es)
LT (1) LT2888281T (es)
MX (1) MX371344B (es)
NZ (3) NZ631562A (es)
PL (3) PL4011915T3 (es)
PT (2) PT4011915T (es)
RS (1) RS58091B1 (es)
RU (1) RU2690675C2 (es)
SG (2) SG10201701331SA (es)
SI (1) SI2888281T1 (es)
TW (1) TWI656880B (es)
UY (1) UY34984A (es)
WO (1) WO2014031610A1 (es)

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