MA46098A - Méthodes de prévention ou de traitement de l'allergie par administration d'un antagoniste d'il-4 r - Google Patents
Méthodes de prévention ou de traitement de l'allergie par administration d'un antagoniste d'il-4 rInfo
- Publication number
- MA46098A MA46098A MA046098A MA46098A MA46098A MA 46098 A MA46098 A MA 46098A MA 046098 A MA046098 A MA 046098A MA 46098 A MA46098 A MA 46098A MA 46098 A MA46098 A MA 46098A
- Authority
- MA
- Morocco
- Prior art keywords
- antagonist
- giving
- preventing
- methods
- treating allergy
- Prior art date
Links
- 206010020751 Hypersensitivity Diseases 0.000 title 1
- 108090000978 Interleukin-4 Proteins 0.000 title 1
- 208000026935 allergic disease Diseases 0.000 title 1
- 230000007815 allergy Effects 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Virology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662382501P | 2016-09-01 | 2016-09-01 | |
US201662425726P | 2016-11-23 | 2016-11-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA46098A true MA46098A (fr) | 2019-07-10 |
Family
ID=59923551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA046098A MA46098A (fr) | 2016-09-01 | 2017-08-31 | Méthodes de prévention ou de traitement de l'allergie par administration d'un antagoniste d'il-4 r |
Country Status (9)
Country | Link |
---|---|
US (2) | US11771743B2 (fr) |
EP (1) | EP3506931B1 (fr) |
JP (2) | JP2019531273A (fr) |
KR (3) | KR20220151021A (fr) |
CN (2) | CN109789196B (fr) |
CA (1) | CA3035202A1 (fr) |
MA (1) | MA46098A (fr) |
MX (2) | MX2019002344A (fr) |
WO (1) | WO2018045130A1 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102502640B1 (ko) | 2012-08-21 | 2023-02-23 | 사노피 바이오테크놀로지 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
TWI697334B (zh) | 2013-06-04 | 2020-07-01 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
JP6526037B2 (ja) | 2014-02-28 | 2019-06-05 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | Il−4rアンタゴニストを投与することによる皮膚感染を処置するための方法 |
IL303337A (en) | 2014-11-14 | 2023-08-01 | Regeneron Pharma | Methods for the treatment of chronic sinusitis with nasal polyps by adding an R4–IL antagonist |
CN107474134B (zh) | 2016-06-08 | 2021-07-27 | 苏州康乃德生物医药有限公司 | 用于结合白细胞介素4受体的抗体 |
KR20220151021A (ko) | 2016-09-01 | 2022-11-11 | 리제너론 파아마슈티컬스, 인크. | Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법 |
US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
PT3515465T (pt) | 2017-08-18 | 2024-03-04 | Regeneron Pharma | Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r |
AU2018359219A1 (en) | 2017-10-30 | 2020-04-23 | Regeneron Pharmaceuticals, Inc. | Methods for treating or preventing asthma by administering an IL-4R antagonist |
CN112153982A (zh) | 2018-05-13 | 2020-12-29 | 瑞泽恩制药公司 | 用于通过施用il-4r抑制剂治疗特应性皮炎的方法 |
CA3119090A1 (fr) * | 2018-11-07 | 2020-05-14 | Seasun Therapeutics | Composition pour la prevention ou le traitement de la dermatite atopique comprenant un complexe d'acide nucleique penetrant dans la peau en tant que principe actif |
US11312778B2 (en) | 2018-11-21 | 2022-04-26 | Brian C. Machler | Method for treating allergic contact dermatitis |
CN110746507B (zh) | 2018-12-25 | 2020-06-26 | 江苏荃信生物医药有限公司 | 抗人白介素4受体α单克隆抗体及其应用 |
CN113597328A (zh) | 2019-03-21 | 2021-11-02 | 瑞泽恩制药公司 | 用于治疗过敏症的il-4/il-13途径抑制剂和浆细胞消融的组合 |
BR112022000581A2 (pt) | 2019-08-05 | 2022-03-03 | Regeneron Pharma | Métodos para tratamento de alergia e intensificação de imunoterapia específica dos alergénos através da administração de um antagonista de il-4r |
WO2021119028A1 (fr) | 2019-12-09 | 2021-06-17 | Sanofi Biotechnology | Méthodesde traitement de troubles associés à l'il-4/il-13 identifiés numériquement |
EP3992974A1 (fr) | 2020-11-02 | 2022-05-04 | Sanofi Biotechnology | Procédés pour le traitement de troubles liés à l'il-13/il-4 identifiés numériquement |
KR20230130681A (ko) * | 2021-01-08 | 2023-09-12 | 리제너론 파아마슈티컬스, 인크. | Il-4r 길항제 투여에 의한 땅콩 알레르기를 치료하는방법 및 땅콩 알레르기원 특이적 면역치료를 강화하는 방법 |
CN114805572B (zh) * | 2021-01-22 | 2022-12-13 | 上海济煜医药科技有限公司 | 抗原结合蛋白及其应用 |
KR20230111729A (ko) | 2022-01-19 | 2023-07-26 | 연세대학교 원주산학협력단 | 단삼 추출물을 유효성분으로 포함하는 알레르기 질환 예방 또는 치료용 조성물 |
WO2023208104A1 (fr) * | 2022-04-29 | 2023-11-02 | 中山康方生物医药有限公司 | Anticorps anti-ra de l'il-4 humaine et son application |
Family Cites Families (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8808015D0 (en) | 1988-04-06 | 1988-05-05 | Ritter M A | Chemical compounds |
AU643427B2 (en) | 1988-10-31 | 1993-11-18 | Immunex Corporation | Interleukin-4 receptors |
JPH06510750A (ja) | 1991-05-03 | 1994-12-01 | セラジェン インク | 炎症性関節炎治療を目的としてインタ−ロイキン受容体を標的にした分子 |
JP3315427B2 (ja) | 1992-03-05 | 2002-08-19 | 大日本除蟲菊株式会社 | 皮膚炎治療剤 |
US5714146A (en) | 1992-08-26 | 1998-02-03 | Board Of Regents Of The University Of Washington | IL-4 bone therapy |
EP0604693A1 (fr) | 1992-12-29 | 1994-07-06 | Schering-Plough | Anticorps monoclonaux contre le récepteur de l'interleukine-4 humain et hydridomes les produisant |
RU2162711C2 (ru) | 1993-09-07 | 2001-02-10 | Смитклайн Бичам Корпорейшн | Рекомбинантные il4-антитела, используемые для лечения нарушений, связанных с действием il4 |
EP1113818B1 (fr) | 1998-09-18 | 2006-05-17 | Dynavax Technologies Corporation | PROCEDES DE TRAITEMENT DE TROUBLES ASSOCIES A IgE ET COMPOSITIONS POUVANT ETRE UTILISEES A CET EFFET |
US6927044B2 (en) | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
EP3190126A1 (fr) | 2000-05-26 | 2017-07-12 | Immunex Corporation | Utilisation d'anticorps contre le recepteur d'interleukine-4 (il-4r) et compositions correspondantes |
US7879328B2 (en) | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
KR100572408B1 (ko) | 2000-07-26 | 2006-04-19 | 가부시키가이샤 호오도 | 진양성 조성물 및 창상치유촉진 조성물 |
IL156276A0 (en) | 2000-12-22 | 2004-01-04 | Nestle Sa | Induction of tolerance |
US20030103938A1 (en) | 2001-05-09 | 2003-06-05 | Alk-Abello A/S | Pharmaceutical compositions for preventing or treating Th1 and Th2 cell related diseases by modulating the Th1/Th2 ratio |
CA2446108A1 (fr) | 2001-05-11 | 2002-11-21 | Novartis Ag | Compositions permettant de traiter les troubles associes aux ige |
WO2002093998A2 (fr) | 2001-05-23 | 2002-11-28 | Duotol Ab | Suppression de reactions allergiques par administration intradermique d'allergenes conjugues avec des sous unites de toxine ou des fragments de celle-ci |
ATE517855T1 (de) | 2001-11-30 | 2011-08-15 | Biogen Idec Inc | Antikörper gegen chemotaktische monozytenproteine |
ES2327830T3 (es) | 2002-03-29 | 2009-11-04 | Schering Corporation | Anticuerpos monoclonales humanos anti-interleuquina-5 y metodos y composiciones que los contienen. |
WO2004047793A1 (fr) | 2002-11-26 | 2004-06-10 | Alk-Abelló A/S | Produit pharmaceutique comprenant des allergenes |
EP1592776A4 (fr) | 2003-02-01 | 2008-06-04 | Tanox Inc | Anticorps ige anti-humains a affinite elevee |
US7923209B2 (en) | 2003-03-14 | 2011-04-12 | Anergis, S.A. | Allergen peptide fragments and use thereof |
AU2004290017B2 (en) | 2003-11-07 | 2012-05-03 | Immunex Corporation | Antibodies that bind interleukin-4 receptor |
WO2005063817A2 (fr) | 2003-12-22 | 2005-07-14 | Amgen Inc. | Procédés d'identification d'anticorps fonctionnels |
CA2554596A1 (fr) | 2004-02-27 | 2005-09-15 | Regeneron Pharmaceuticals, Inc. | Polypeptides specifiques d'il-4/il-13 et utilisations therapeutiques associees |
US20090098142A1 (en) | 2004-06-09 | 2009-04-16 | Kasaian Marion T | Methods and compositions for treating and monitoring treatment of IL-13-associated disorders |
TWI307630B (en) | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
JP5234445B2 (ja) | 2004-10-05 | 2013-07-10 | 源一郎 杣 | 薬剤 |
US8030003B2 (en) | 2004-12-07 | 2011-10-04 | Children's Hospital Medical Center | Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3 |
TW200902555A (en) | 2005-01-03 | 2009-01-16 | Hoffmann La Roche | Antibodies against IL-13 receptor alpha 1 and uses thereof |
EP2301969B1 (fr) | 2005-05-06 | 2015-12-23 | ZymoGenetics, Inc. | Anticorps monoclonaux IL-31 et procédés d'utilisation |
US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
US8679545B2 (en) | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
MY147468A (en) | 2006-06-02 | 2012-12-14 | Regeneron Pharma | High affinity antibodies to human il-6 receptor |
JP4221018B2 (ja) | 2006-08-31 | 2009-02-12 | トヨタ自動車株式会社 | 頭部保護エアバッグ装置 |
CN101522716B (zh) | 2006-10-02 | 2013-03-20 | 瑞泽恩制药公司 | 抗人il-4受体的高亲和力人抗体 |
US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
KR101555068B1 (ko) | 2007-03-22 | 2015-10-06 | 제넨테크, 인크. | 막 결합형 ige에 결합하는 세포자멸성 항-ige 항체 |
EP2022507A1 (fr) | 2007-08-07 | 2009-02-11 | Universität Hamburg | Compositions d'anticorps spécifiques pour les épitopes des lgE, lgG4 et lgA en tant qu'outils pour la création de molécules hypoallergéniques pour l'immunothérapie spécifique |
US8637239B2 (en) | 2007-11-05 | 2014-01-28 | The Board Of Trustees Of The University Of Illinois | Minimally-invasive measurement of esophageal inflammation |
US8092804B2 (en) | 2007-12-21 | 2012-01-10 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (IL-4Rα)-173 |
DE202008006598U1 (de) | 2008-04-11 | 2008-10-02 | Alk-Abelló A/S | Allergie-Impfstoff-Formulierung zur mucosalen Verabreichung |
US20090264392A1 (en) | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
WO2010065557A2 (fr) | 2008-12-01 | 2010-06-10 | Cincinnati Children's Hospital Medical Center | Procédés de détermination de l'efficacité d'un traitement par glucocorticoïde de l'oesophagite à éosinophiles |
WO2010120524A2 (fr) | 2009-03-31 | 2010-10-21 | Altair Therapeutics, Inc. | Procédés de modulation d'une réponse immunitaire à une infection virale |
US8497528B2 (en) | 2010-05-06 | 2013-07-30 | Taiwan Semiconductor Manufacturing Company, Ltd. | Method for fabricating a strained structure |
JP5879265B2 (ja) | 2009-09-07 | 2016-03-08 | デベヴェ・テクノロジーズ | 好酸球性食道炎を処置する方法 |
US8993347B2 (en) | 2009-12-17 | 2015-03-31 | Cornell University | Methods for detecting antibodies in mucosal samples and device for sampling mucosal material |
EP3970726A1 (fr) | 2010-06-24 | 2022-03-23 | ViroPharma Biologics LLC | Procédés de traitement de l'inflammation de l' sophage |
EA028945B1 (ru) | 2010-10-06 | 2018-01-31 | Ридженерон Фармасьютикалз, Инк. | СТАБИЛЬНЫЕ ЖИДКИЕ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ АНТИТЕЛА К АЛЬФА РЕЦЕПТОРУ ЧЕЛОВЕЧЕСКОГО ИНТЕРЛЕЙКИНА-4 (hIL-4Rα) |
TR201802772T4 (tr) | 2010-11-17 | 2018-03-21 | Chugai Pharmaceutical Co Ltd | Kan pıhtılaşma faktörü VIII in işlevi için alternatif işleve sahip multi-spesifik antijen bağlayıcı molekül. |
RU2453303C1 (ru) | 2010-12-23 | 2012-06-20 | Общество с ограниченной ответственностью "ЦитоНИР" (ООО "ЦитоНИР") | Фармацевтическая композиция для лечения атопического дерматита |
CA2824043A1 (fr) | 2011-01-06 | 2012-07-12 | Marc E. Rothenberg | Profils d'expression de cytokine oesophagienne dans l'oesophagite a eosinophiles |
US20130052190A1 (en) | 2011-02-22 | 2013-02-28 | Oxagen Limited | CRTH2 Antagonists for Treatment of Eosinophilic Diseases and Conditions |
WO2012177945A2 (fr) | 2011-06-21 | 2012-12-27 | Children's Hospital Medical Center | Méthodes de diagnostic pour œsophagite à éosinophiles |
US8790651B2 (en) | 2011-07-21 | 2014-07-29 | Zoetis Llc | Interleukin-31 monoclonal antibody |
CN103974706A (zh) | 2011-10-06 | 2014-08-06 | N·V·努特里奇亚 | 嗜酸细胞性食管炎的治疗 |
WO2013088109A1 (fr) | 2011-12-16 | 2013-06-20 | Oxagen Limited | Combinaison d'un antagoniste de crth2 et d'un inhibiteur de pompe à protons pour le traitement de l'œsophagite à éosinophiles |
BR112014018471A2 (pt) | 2012-01-31 | 2017-07-04 | Genentech Inc | anticorpos anti-ige m1' e métodos para o seu uso |
WO2013155010A1 (fr) | 2012-04-09 | 2013-10-17 | Children's Hospital Medical Center | Biomarqueurs non invasifs pour l'œsophagite éosinophile |
KR102502640B1 (ko) * | 2012-08-21 | 2023-02-23 | 사노피 바이오테크놀로지 | Il-4r 길항제의 투여에 의한 천식의 치료 또는 예방 방법 |
LT2892927T (lt) | 2012-09-07 | 2018-09-10 | Regeneron Pharmaceuticals, Inc. | Atopinio dermatito gydymo būdai, skiriant il-4r antagonistą |
US10132809B2 (en) | 2012-10-10 | 2018-11-20 | Rhote Island Hospital | Differential expression of protein markers for the diagnosis and treatment of eosinophilic esophagitis |
EP2953974B1 (fr) | 2013-02-05 | 2017-12-20 | EngMab Sàrl | Anticorps bispécifiques contre cd3 et bcma |
TWI697334B (zh) | 2013-06-04 | 2020-07-01 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
WO2014205365A1 (fr) | 2013-06-21 | 2014-12-24 | Sanofi | Méthodes de traitement de la polypose nasale par administration d'un antagoniste d'il-4 r |
TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
RU2552929C1 (ru) | 2013-11-14 | 2015-06-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний |
JP6673840B2 (ja) | 2014-02-21 | 2020-03-25 | サノフィ・バイオテクノロジー | Il−4r拮抗薬の投与により喘息を処置または予防するための方法 |
JP6526037B2 (ja) | 2014-02-28 | 2019-06-05 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. | Il−4rアンタゴニストを投与することによる皮膚感染を処置するための方法 |
IL303337A (en) | 2014-11-14 | 2023-08-01 | Regeneron Pharma | Methods for the treatment of chronic sinusitis with nasal polyps by adding an R4–IL antagonist |
MX2018009990A (es) | 2016-02-19 | 2018-12-17 | Regeneron Pharma | Metodos para mejorar la eficacia de una vacuna mediante la administracion de un antagonista il-4r. |
TWI728172B (zh) | 2016-08-18 | 2021-05-21 | 美商愛戴爾製藥股份有限公司 | 治療嗜伊紅性食道炎之方法 |
KR20220151021A (ko) | 2016-09-01 | 2022-11-11 | 리제너론 파아마슈티컬스, 인크. | Il-4r 길항제를 투여함에 의해 알레르기를 예방하거나 치료하기 위한 방법 |
AU2017332732B2 (en) | 2016-09-22 | 2024-03-14 | Regeneron Pharmaceuticals, Inc. | Methods for treating severe atopic dermatitis by administering an IL-4R inhibitor |
CA3052779A1 (fr) | 2017-02-17 | 2018-08-23 | Fred Hutchinson Cancer Research Center | Traitements d'association pour le traitement de cancers associes a bcma et de troubles auto-immuns |
EP3615068A1 (fr) | 2017-04-28 | 2020-03-04 | Novartis AG | Agent ciblant le bcma et polythérapie incluant un inhibiteur de gamma-sécrétase |
US11053309B2 (en) | 2017-08-04 | 2021-07-06 | Regeneron Pharmaceuticals, Inc. | Methods for treating active eosinophilic esophagitis |
PT3515465T (pt) | 2017-08-18 | 2024-03-04 | Regeneron Pharma | Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r |
AU2018359219A1 (en) | 2017-10-30 | 2020-04-23 | Regeneron Pharmaceuticals, Inc. | Methods for treating or preventing asthma by administering an IL-4R antagonist |
CN112153982A (zh) | 2018-05-13 | 2020-12-29 | 瑞泽恩制药公司 | 用于通过施用il-4r抑制剂治疗特应性皮炎的方法 |
EP4406975A2 (fr) | 2018-06-14 | 2024-07-31 | Ajinomoto Co., Inc. | Composé ayant une substance d'affinité pour un anticorps et un groupe fonctionnel bioorthogonal, ou un sel de celui-ci |
CN113597328A (zh) | 2019-03-21 | 2021-11-02 | 瑞泽恩制药公司 | 用于治疗过敏症的il-4/il-13途径抑制剂和浆细胞消融的组合 |
KR20220004708A (ko) | 2019-05-01 | 2022-01-11 | 사노피 바이오테크놀로지 | Il-33 길항제를 투여하여 천식을 치료 또는 예방하는 방법 |
MX2022001247A (es) | 2019-08-05 | 2022-04-25 | Regeneron Pharma | Metodos para tratar dermatitis atopica mediante la administracion de un antagonista il-4r. |
BR112022000581A2 (pt) | 2019-08-05 | 2022-03-03 | Regeneron Pharma | Métodos para tratamento de alergia e intensificação de imunoterapia específica dos alergénos através da administração de um antagonista de il-4r |
WO2021119028A1 (fr) | 2019-12-09 | 2021-06-17 | Sanofi Biotechnology | Méthodesde traitement de troubles associés à l'il-4/il-13 identifiés numériquement |
KR20220158821A (ko) | 2020-03-27 | 2022-12-01 | 리제너론 파아마슈티컬스, 인크. | Il-4r 길항제를 투여함에 의해 아토피 피부염을 치료하기 위한 방법 |
BR112022022235A2 (pt) | 2020-05-22 | 2023-03-28 | Regeneron Pharma | Métodos para tratamento de esofagite eosinofílica através da administração de inibidor de il-4r |
KR20230130681A (ko) | 2021-01-08 | 2023-09-12 | 리제너론 파아마슈티컬스, 인크. | Il-4r 길항제 투여에 의한 땅콩 알레르기를 치료하는방법 및 땅콩 알레르기원 특이적 면역치료를 강화하는 방법 |
-
2017
- 2017-08-31 KR KR1020227037662A patent/KR20220151021A/ko not_active IP Right Cessation
- 2017-08-31 EP EP17771619.8A patent/EP3506931B1/fr active Active
- 2017-08-31 KR KR1020247014525A patent/KR20240065318A/ko active Search and Examination
- 2017-08-31 KR KR1020197009282A patent/KR102462039B1/ko active IP Right Grant
- 2017-08-31 CN CN201780053319.2A patent/CN109789196B/zh active Active
- 2017-08-31 CN CN202410243164.0A patent/CN118141914A/zh active Pending
- 2017-08-31 US US16/329,184 patent/US11771743B2/en active Active
- 2017-08-31 MX MX2019002344A patent/MX2019002344A/es unknown
- 2017-08-31 WO PCT/US2017/049538 patent/WO2018045130A1/fr unknown
- 2017-08-31 JP JP2019511889A patent/JP2019531273A/ja active Pending
- 2017-08-31 CA CA3035202A patent/CA3035202A1/fr active Pending
- 2017-08-31 MA MA046098A patent/MA46098A/fr unknown
-
2019
- 2019-02-27 MX MX2023004306A patent/MX2023004306A/es unknown
-
2022
- 2022-08-26 JP JP2022134609A patent/JP2022169718A/ja active Pending
-
2023
- 2023-08-18 US US18/452,155 patent/US20240082353A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN118141914A (zh) | 2024-06-07 |
KR20240065318A (ko) | 2024-05-14 |
US20240082353A1 (en) | 2024-03-14 |
CA3035202A1 (fr) | 2018-03-08 |
CN109789196B (zh) | 2024-03-19 |
EP3506931B1 (fr) | 2024-07-31 |
JP2019531273A (ja) | 2019-10-31 |
KR20190042702A (ko) | 2019-04-24 |
MX2019002344A (es) | 2019-09-06 |
KR20220151021A (ko) | 2022-11-11 |
JP2022169718A (ja) | 2022-11-09 |
US20190183973A1 (en) | 2019-06-20 |
US11771743B2 (en) | 2023-10-03 |
EP3506931A1 (fr) | 2019-07-10 |
WO2018045130A1 (fr) | 2018-03-08 |
MX2023004306A (es) | 2023-05-04 |
CN109789196A (zh) | 2019-05-21 |
KR102462039B1 (ko) | 2022-11-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA46098A (fr) | Méthodes de prévention ou de traitement de l'allergie par administration d'un antagoniste d'il-4 r | |
MA45192A (fr) | Traitement d'association | |
MA52371A (fr) | Méthodes de traitement d'infections dues aux coronaviridae | |
MA46954A (fr) | Méthodes de traitement d'états inflammatoires | |
DK3698847T3 (da) | Magnetisk stimuleringsudstyr til terapeutisk behandling | |
MA40867A (fr) | Méthodes pour le traitement d'infections virales à filoviridae | |
EA201692316A1 (ru) | Производные холана для применения при лечении и/или профилактике fxr и tgr5/gpbar1-опосредованных заболеваний | |
MA48996A (fr) | Méthodes de traitement de maladies neurodégénératives | |
DK3169328T3 (da) | Quinolinderivater til behandling af inflammationssygdomme | |
MA44234A (fr) | Procédés de traitement ou de prévention de l'athérosclérose par administration d'un inhibiteur d'angptl3 | |
EA201890185A1 (ru) | Способы лечения опосредованных гепсидином нарушений | |
DK3393579T3 (da) | Øjenbehandlingssystem | |
MA45675A (fr) | Méthodes et compositions permettant le traitement du cancer | |
EA201791454A1 (ru) | Лекарственные формы для трансдермального введения | |
MA42999A (fr) | Polythérapie pour le traitement de malignités | |
DK3430143T3 (da) | Inhibitorer af SRSF1 til behandlingen af neurodegenerative sygdomme | |
MA53568A (fr) | Médicaments pour le traitement de maladies ophtalmiques | |
ES2893126T8 (es) | Métodos de tratamiento de afecciones oculares | |
MA45226A (fr) | Compositions et méthodes de traitement ou de prévention d'affections liées à l'oxalate | |
DK3451886T3 (da) | Gulvbehandlingssystem | |
DK3236983T3 (da) | Hidtil ukendt pi3k-gamma-inhibitorpeptid til behandling af sygdomme i åndedrætssystemet | |
DK3578562T3 (da) | L-valinatamidbenzoxaborolderivater til behandling af parasitiske sygdomme | |
MA51525A (fr) | Traitement de minéraux | |
MA47595A (fr) | Méthodes de traitement d'affections neurodégénératives | |
FR3022139B1 (fr) | Nouvelles compositions pour le traitement des rougeurs cutanees et de la rosacee |