MA44238B1 - Procédés d'augmentation de l'efficacité d'un vaccin par administration d'un antagoniste d'il-4r - Google Patents
Procédés d'augmentation de l'efficacité d'un vaccin par administration d'un antagoniste d'il-4rInfo
- Publication number
- MA44238B1 MA44238B1 MA44238A MA44238A MA44238B1 MA 44238 B1 MA44238 B1 MA 44238B1 MA 44238 A MA44238 A MA 44238A MA 44238 A MA44238 A MA 44238A MA 44238 B1 MA44238 B1 MA 44238B1
- Authority
- MA
- Morocco
- Prior art keywords
- methods
- antagonist
- administration
- vaccine
- vaccine efficacy
- Prior art date
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Abstract
La présente invention concerne des procédés d'amélioration de l'efficacité et/ou la sécurité d'un vaccin. Dans certains modes de réalisation, l'invention concerne des procédés d'augmentation ou de potentialisation de la réponse immunitaire à un vaccin chez un sujet en ayant besoin. Les procédés de la présente invention comprennent l'administration à un sujet en ayant besoin d'un antagoniste de récepteur d'interleukine 4 (IL-4R) tel qu'un anticorps anti-IL-4R en combinaison avec ledit vaccin. Dans certains modes de réalisation, les procédés de la présente invention sont utilisés pour obtenir une protection améliorée contre une maladie infectieuse telle que la coqueluche.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662297257P | 2016-02-19 | 2016-02-19 | |
| US201662409936P | 2016-10-19 | 2016-10-19 | |
| PCT/US2017/018487 WO2017143270A1 (fr) | 2016-02-19 | 2017-02-17 | Procédés d'augmentation de l'efficacité d'un vaccin par administration d'un antagoniste d'il-4r |
| EP17708398.7A EP3416685B1 (fr) | 2016-02-19 | 2017-02-17 | Procédés d'augmentation de l'efficacité d'un vaccin par administration d'un antagoniste d'il-4r |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA44238A MA44238A (fr) | 2018-12-26 |
| MA44238B1 true MA44238B1 (fr) | 2024-07-31 |
Family
ID=58192407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA44238A MA44238B1 (fr) | 2016-02-19 | 2017-02-17 | Procédés d'augmentation de l'efficacité d'un vaccin par administration d'un antagoniste d'il-4r |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US10314904B2 (fr) |
| EP (2) | EP3416685B1 (fr) |
| JP (3) | JP7597500B2 (fr) |
| KR (1) | KR102868264B1 (fr) |
| CN (1) | CN109069625A (fr) |
| AU (2) | AU2017220184B2 (fr) |
| CA (1) | CA3014202A1 (fr) |
| ES (1) | ES2983475T3 (fr) |
| HU (1) | HUE067673T2 (fr) |
| IL (1) | IL261025A (fr) |
| MA (1) | MA44238B1 (fr) |
| MX (2) | MX2018009990A (fr) |
| PL (1) | PL3416685T3 (fr) |
| PT (1) | PT3416685T (fr) |
| RU (1) | RU2753869C2 (fr) |
| WO (1) | WO2017143270A1 (fr) |
| ZA (1) | ZA201805295B (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| WO2014031610A1 (fr) | 2012-08-21 | 2014-02-27 | Sanofi | Procédés permettant de traiter ou d'empêcher l'asthme par administration d'un antagoniste du récepteur à l'interleukine 4 (il-4r) |
| HRP20181227T1 (hr) | 2012-09-07 | 2018-10-05 | Regeneron Pharmaceuticals, Inc. | Metode za liječenje atopijskog dermatitisa primjenom antagonista il-4r |
| TWI755763B (zh) | 2013-06-04 | 2022-02-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
| RU2704999C2 (ru) | 2014-02-28 | 2019-11-01 | Ридженерон Фармасьютикалз, Инк. | Способ лечения кожной инфекции путем введения антагониста il-4r |
| US10066017B2 (en) | 2014-11-14 | 2018-09-04 | Sanofi Biotechnology | Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist |
| US12070492B2 (en) * | 2016-05-10 | 2024-08-27 | Hennepin Healthcare Research Institute | Therapeutic compositions and methods with cytokine signaling immunomodulators |
| CN109789196B (zh) * | 2016-09-01 | 2024-03-19 | 瑞泽恩制药公司 | 用于通过施用il-4r拮抗剂来预防或治疗变态反应的方法 |
| WO2019028367A1 (fr) | 2017-08-04 | 2019-02-07 | Regeneron Pharmaceuticals, Inc. | Méthodes de traitement de l'oesophagite à éosinophiles active |
| PT3515465T (pt) | 2017-08-18 | 2024-03-04 | Regeneron Pharma | Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r |
| PL3703818T3 (pl) | 2017-10-30 | 2024-03-25 | Sanofi Biotechnology | Antagonista IL-4R do zastosowania w sposobie leczenia lub zapobiegania astmie |
| EP3793597A1 (fr) | 2018-05-13 | 2021-03-24 | Regeneron Pharmaceuticals, Inc. | Méthodes de traitement de la dermatite atopique par administration d'un inhibiteur de l'il-4r |
| WO2020092015A1 (fr) | 2018-11-02 | 2020-05-07 | University Of Rochester | Atténuation thérapeutique d'une infection épithéliale |
| SG11202109003QA (en) * | 2019-03-06 | 2021-09-29 | Regeneron Pharma | Il-4/il-13 pathway inhibitors for enhanced efficacy in treating cancer |
| MA55372A (fr) | 2019-03-21 | 2022-01-26 | Regeneron Pharma | Combinaison d'inhibiteurs de la voie il-4/il-13 et d'ablation de plasmocytes pour traiter une allergie |
| JP7592064B2 (ja) | 2019-07-16 | 2024-11-29 | サノフィ・バイオテクノロジー | Il-4rアンタゴニストを投与することにより喘息を治療するまたは予防するための方法 |
| CN114173819A (zh) | 2019-08-05 | 2022-03-11 | 瑞泽恩制药公司 | 通过施用il-4r拮抗剂治疗过敏和增强过敏原特异性免疫疗法的方法 |
| AU2020326713A1 (en) | 2019-08-05 | 2022-02-17 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r antagonist |
| EP3992974A1 (fr) | 2020-11-02 | 2022-05-04 | Sanofi Biotechnology | Procédés pour le traitement de troubles liés à l'il-13/il-4 identifiés numériquement |
| EP4073810A1 (fr) | 2019-12-09 | 2022-10-19 | Sanofi Biotechnology | Méthodes de traitement de troubles associés à l'il-4/il-13 identifiés numériquement |
| WO2021195530A1 (fr) * | 2020-03-27 | 2021-09-30 | Regeneron Pharmaceuticals, Inc. | Méthodes de traitement de la dermatite atopique par administration d'un antagoniste de l'il-4r |
| US20240336688A1 (en) * | 2021-07-22 | 2024-10-10 | Icahn School Of Medicine At Mount Sinai | Dual-blockade of il-4 signaling and immune checkpoint proteins for treating cancer |
| JP2024532263A (ja) * | 2021-08-23 | 2024-09-05 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Il-4rアンタゴニストを投与することによってアトピー性皮膚炎を治療する方法 |
| CN118717989A (zh) * | 2024-05-27 | 2024-10-01 | 中国人民解放军军事科学院军事医学研究院 | Il-4r拮抗剂在制备预防和/或治疗流感病毒感染的药物中的应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE16192152T1 (de) | 2000-05-26 | 2020-08-06 | Immunex Corporation | Verwendung von interleukin-4 rezeptor (il-4r) antikörpern und zusammensetzungen davon |
| US20030139364A1 (en) * | 2001-10-12 | 2003-07-24 | University Of Iowa Research Foundation | Methods and products for enhancing immune responses using imidazoquinoline compounds |
| GB0217920D0 (en) * | 2002-04-23 | 2002-09-11 | Aventis Pharm Prod Inc | Interleukin-4 Gene Expression inhibitors |
| GEP20104991B (en) | 2003-11-07 | 2010-05-25 | Immunex Corp | Antibodies that bind interleukin-4 receptor |
| WO2008054606A2 (fr) | 2006-10-02 | 2008-05-08 | Regeneron Pharmaceuticals, Inc. | Anticorps humains à haute affinité vis-à-vis du récepteur il-4 humain |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| RU2490278C2 (ru) | 2007-12-21 | 2013-08-20 | Медиммун Лимитед | ЭЛЕМЕНТ, СВЯЗЫВАЮЩИЙСЯ С α-РЕЦЕПТОРОМ ИНТЕРЛЕЙКИНА-4 (IL-4Rα)-173 |
| US8092804B2 (en) | 2007-12-21 | 2012-01-10 | Medimmune Limited | Binding members for interleukin-4 receptor alpha (IL-4Rα)-173 |
| EP2414520A2 (fr) * | 2009-03-31 | 2012-02-08 | Altair Therapeutics, Inc. | Procédés de modulation d'une réponse immunitaire à une infection virale |
| PL2624865T3 (pl) | 2010-10-06 | 2018-11-30 | Regeneron Pharmaceuticals, Inc. | Stabilizowane preparaty zawierające przeciwciała przeciwko receptorowi interleukiny-4 (IL-4R) |
| SG11201408101TA (en) * | 2012-06-05 | 2015-01-29 | Univ Australian | Vaccination with interleukin-4 antagonists |
| HRP20181227T1 (hr) | 2012-09-07 | 2018-10-05 | Regeneron Pharmaceuticals, Inc. | Metode za liječenje atopijskog dermatitisa primjenom antagonista il-4r |
| TWI755763B (zh) * | 2013-06-04 | 2022-02-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| PT3613432T (pt) | 2014-05-07 | 2025-10-29 | Regeneron Pharma | Métodos para tratar a polipose nasal através da administração de um antagonista de il-4r |
| KR20190062142A (ko) * | 2017-11-28 | 2019-06-05 | (주)비티엔 | 면역 증강 활성을 가지는 아미노산 미네랄 복합체 및 이를 포함하는 식품, 약학 또는 사료용 조성물 |
| US20210361700A1 (en) * | 2020-05-22 | 2021-11-25 | Trustees Of Tufts College | Nutritional supplement to combat covid-19 and aid vaccination |
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2017
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- 2017-02-17 HU HUE17708398A patent/HUE067673T2/hu unknown
- 2017-02-17 AU AU2017220184A patent/AU2017220184B2/en active Active
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- 2017-02-17 JP JP2018543637A patent/JP7597500B2/ja active Active
- 2017-02-17 WO PCT/US2017/018487 patent/WO2017143270A1/fr not_active Ceased
- 2017-02-17 RU RU2018133011A patent/RU2753869C2/ru active
- 2017-02-17 EP EP17708398.7A patent/EP3416685B1/fr not_active Revoked
- 2017-02-17 PT PT177083987T patent/PT3416685T/pt unknown
- 2017-02-17 EP EP24174931.6A patent/EP4420733A3/fr not_active Withdrawn
- 2017-02-17 CN CN201780014809.1A patent/CN109069625A/zh active Pending
- 2017-02-17 CA CA3014202A patent/CA3014202A1/fr active Pending
- 2017-02-17 US US15/436,032 patent/US10314904B2/en active Active
- 2017-02-17 KR KR1020187026017A patent/KR102868264B1/ko active Active
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2018
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2019
- 2019-04-29 US US16/398,143 patent/US20190321457A1/en not_active Abandoned
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2022
- 2022-09-26 JP JP2022152120A patent/JP7813209B2/ja active Active
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2023
- 2023-07-05 US US18/218,459 patent/US20240082380A1/en not_active Abandoned
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