EA201690378A1 - Вакцинные композиции против наркотической зависимости - Google Patents

Вакцинные композиции против наркотической зависимости

Info

Publication number
EA201690378A1
EA201690378A1 EA201690378A EA201690378A EA201690378A1 EA 201690378 A1 EA201690378 A1 EA 201690378A1 EA 201690378 A EA201690378 A EA 201690378A EA 201690378 A EA201690378 A EA 201690378A EA 201690378 A1 EA201690378 A1 EA 201690378A1
Authority
EA
Eurasian Patent Office
Prior art keywords
vaccine compositions
compositions against
narcotic dependence
against narcotic
dependence
Prior art date
Application number
EA201690378A
Other languages
English (en)
Other versions
EA032441B1 (ru
Inventor
Кристофер Х. Клегг
Original Assignee
Иммьюн Дизайн Корп.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Иммьюн Дизайн Корп. filed Critical Иммьюн Дизайн Корп.
Publication of EA201690378A1 publication Critical patent/EA201690378A1/ru
Publication of EA032441B1 publication Critical patent/EA032441B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0013—Therapeutic immunisation against small organic molecules, e.g. cocaine, nicotine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]

Abstract

Настоящее изобретение в целом относится к вакцинам против наркотической зависимости. В частности, настоящее раскрытие относится к адъювантам для значительного усовершенствования иммунного ответа, возникающего против гаптенов аддиктивного вещества.
EA201690378A 2013-09-05 2014-09-04 Вакцинные композиции против никотиновой зависимости EA032441B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361874159P 2013-09-05 2013-09-05
US201462022490P 2014-07-09 2014-07-09
PCT/US2014/054038 WO2015035010A1 (en) 2013-09-05 2014-09-04 Vaccine compositions for drug addiction

Publications (2)

Publication Number Publication Date
EA201690378A1 true EA201690378A1 (ru) 2016-06-30
EA032441B1 EA032441B1 (ru) 2019-05-31

Family

ID=52628917

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201690378A EA032441B1 (ru) 2013-09-05 2014-09-04 Вакцинные композиции против никотиновой зависимости

Country Status (8)

Country Link
US (1) US20160193326A1 (ru)
EP (1) EP3041478A4 (ru)
JP (1) JP2016532712A (ru)
CN (1) CN105517555A (ru)
AU (1) AU2014315275A1 (ru)
EA (1) EA032441B1 (ru)
HK (1) HK1224187A1 (ru)
WO (1) WO2015035010A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017261687B2 (en) * 2016-05-10 2023-10-19 Hennepin Healthcare Research Institute Cytokine signaling immunomodulators and methods
CN108396011B (zh) * 2017-07-02 2020-11-27 杭州隆基生物技术有限公司 抗羟考酮单克隆抗体、杂交瘤细胞株的制备及其应用
CN110078734B (zh) * 2019-05-14 2020-07-31 深圳市易瑞生物技术股份有限公司 佐匹克隆半抗原、抗原、抗体、胶体金层析检测装置及其用途

Family Cites Families (23)

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US20020032316A1 (en) * 1995-03-31 2002-03-14 Cantab Pharmaceuticals Research Limited Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
DK1096954T3 (da) * 1998-07-14 2005-01-31 Wyeth Corp Adjuvans- og vaccinesammensætninger indeholdende monophosphoryllipid A
EP2392345A3 (en) * 2002-07-18 2012-03-07 Cytos Biotechnology AG Hapten-carrier conjugates comprising virus like particles and uses thereof
US20080206161A1 (en) * 2002-10-25 2008-08-28 Dov Tamarkin Quiescent foamable compositions, steroids, kits and uses thereof
PL2484375T3 (pl) * 2006-09-26 2018-09-28 Infectious Disease Research Institute Kompozycja szczepionki zawierająca syntetyczny adiuwant
WO2008059307A2 (en) * 2006-11-16 2008-05-22 Om Pharma Functionalized beta 1,6 glucosamine disaccharides and process for their preparation
CA2698668A1 (en) * 2007-09-07 2009-03-19 University Of Georgia Research Foundation, Inc. Synthetic lipid a derivative
WO2009109428A2 (en) * 2008-02-01 2009-09-11 Alpha-O Peptides Ag Self-assembling peptide nanoparticles useful as vaccines
EP2313108A4 (en) * 2008-06-30 2013-06-12 Us Army As Represented By The Secretary Of The Army ANTIPALUDE VACCINE OF SELF-ASSEMBLED POLYPEPTIDE NANOPARTICLES
JP2012502972A (ja) * 2008-09-18 2012-02-02 ノバルティス アーゲー ワクチンアジュバントの組み合わせ
TWI549688B (zh) * 2009-06-05 2016-09-21 美國疾病傳染研究機構 合成的葡萄吡喃糖基脂質佐劑
WO2011000889A1 (en) * 2009-06-30 2011-01-06 William Henry Topical vaccine formulations and methods of treating drug addiction using same
US20110305748A1 (en) * 2010-03-11 2011-12-15 Immune Design, Corp. Vaccines for Pandemic Influenza
TWI578997B (zh) * 2010-06-04 2017-04-21 輝瑞疫苗有限責任公司 用於預防或治療菸鹼成癮之共軛體
CA2810011A1 (en) * 2010-09-01 2012-03-08 Novartis Ag Adsorption of immunopotentiators to insoluble metal salts
TW201309799A (zh) * 2011-02-15 2013-03-01 Immune Design Corp 藉由載體化疫苗增強免疫原特異性免疫反應之方法
EA027236B1 (ru) * 2011-04-08 2017-07-31 Иммьюн Дизайн Корп. Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа
US8323662B1 (en) * 2012-03-30 2012-12-04 Immune Design Corp. Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
CA2888721A1 (en) * 2012-10-25 2014-05-01 Glaxosmithkline Biologicals Sa Nicotinamide as adjuvant
US9149522B2 (en) * 2013-09-25 2015-10-06 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9149521B2 (en) * 2013-09-25 2015-10-06 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
US9017698B2 (en) * 2013-09-25 2015-04-28 Sequoia Sciences, Inc. Compositions of vaccines and adjuvants and methods for the treatment of urinary tract infections
WO2015164798A1 (en) * 2014-04-25 2015-10-29 Tria Bioscience Corp. Synthetic hapten carrier compositions and methods

Also Published As

Publication number Publication date
EP3041478A4 (en) 2017-04-26
WO2015035010A1 (en) 2015-03-12
JP2016532712A (ja) 2016-10-20
AU2014315275A1 (en) 2016-03-10
EA032441B1 (ru) 2019-05-31
CN105517555A (zh) 2016-04-20
EP3041478A1 (en) 2016-07-13
US20160193326A1 (en) 2016-07-07
HK1224187A1 (zh) 2017-08-18

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM RU