BR112015000530A2 - vacina de antígeno micobacteriano. - Google Patents
vacina de antígeno micobacteriano.Info
- Publication number
- BR112015000530A2 BR112015000530A2 BR112015000530A BR112015000530A BR112015000530A2 BR 112015000530 A2 BR112015000530 A2 BR 112015000530A2 BR 112015000530 A BR112015000530 A BR 112015000530A BR 112015000530 A BR112015000530 A BR 112015000530A BR 112015000530 A2 BR112015000530 A2 BR 112015000530A2
- Authority
- BR
- Brazil
- Prior art keywords
- antigen vaccine
- mycobacterial antigen
- mycobacterial
- vaccine
- antigen
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12305825 | 2012-07-10 | ||
EP12306539 | 2012-12-07 | ||
EP13305737 | 2013-06-03 | ||
PCT/EP2013/064624 WO2014009438A2 (en) | 2012-07-10 | 2013-07-10 | Mycobacterial antigen vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015000530A2 true BR112015000530A2 (pt) | 2018-08-28 |
Family
ID=48782326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015000530A BR112015000530A2 (pt) | 2012-07-10 | 2013-07-10 | vacina de antígeno micobacteriano. |
Country Status (17)
Country | Link |
---|---|
US (1) | US10357555B2 (pt) |
EP (1) | EP2872172B1 (pt) |
JP (1) | JP6333814B2 (pt) |
KR (1) | KR20150058152A (pt) |
CN (1) | CN104640564B (pt) |
BR (1) | BR112015000530A2 (pt) |
CA (1) | CA2878800A1 (pt) |
EA (1) | EA029492B1 (pt) |
HK (1) | HK1207962A1 (pt) |
IL (1) | IL236650B (pt) |
MX (1) | MX366206B (pt) |
MY (1) | MY173004A (pt) |
SG (1) | SG11201500171YA (pt) |
TW (1) | TWI638829B (pt) |
UA (1) | UA119228C2 (pt) |
WO (1) | WO2014009438A2 (pt) |
ZA (1) | ZA201500784B (pt) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014009438A2 (en) * | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterial antigen vaccine |
EP4176897A1 (en) * | 2013-06-25 | 2023-05-10 | International AIDS Vaccine Initiative, Inc. | Tuberculosis compositions and methods of using the same |
CN106103471B (zh) * | 2014-01-09 | 2020-01-07 | 特兰斯吉恩股份有限公司 | 异源寡聚分枝杆菌抗原的融合 |
GB201400819D0 (en) | 2014-01-17 | 2014-03-05 | Sec Dep For Health The | Mycobacterial antigen composition |
US20170056345A1 (en) * | 2014-02-18 | 2017-03-02 | Stc.Unm | Booster drug therapy for mycobacterium infections |
WO2016087457A1 (en) | 2014-12-01 | 2016-06-09 | Transgene Sa | Stable liquid vaccinia virus formulations |
WO2016131945A1 (en) | 2015-02-20 | 2016-08-25 | Transgene Sa | Combination product with autophagy modulator |
CN105601747B (zh) * | 2015-10-21 | 2019-05-28 | 中山大学 | 一种结核杆菌融合蛋白及其在诱导外周血单个核细胞产生细胞因子的应用 |
KR101631054B1 (ko) * | 2015-12-31 | 2016-06-16 | 중앙대학교 산학협력단 | 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편 |
CN105567660B (zh) * | 2016-01-08 | 2018-11-20 | 中国人民解放军第四军医大学 | 一种大肠杆菌重组表达结核分枝杆菌Rv2837c活性蛋白的方法及其应用 |
WO2017191147A1 (en) | 2016-05-04 | 2017-11-09 | Transgene Sa | Combination therapy with cpg tlr9 ligand |
JP2019521095A (ja) * | 2016-05-21 | 2019-07-25 | インフェクシャス ディズィーズ リサーチ インスティチュート | 二次性結核および非結核性マイコバクテリウム感染症を治療するための組成物および方法 |
CN109890411A (zh) | 2016-06-16 | 2019-06-14 | 国际艾滋病疫苗行动组织公司 | 结核病组合物和治疗或预防结核病的方法 |
US11091775B2 (en) * | 2016-06-22 | 2021-08-17 | Oregon Health And Science University | Recombinant cytomegalovirus vectors as vaccines for tuberculosis |
MX2019003035A (es) | 2016-09-16 | 2019-09-13 | Infectious Disease Res Inst | Vacunas que comprenden polipeptidos de mycobacterium leprae para la prevencion, el tratamiento y el diagnostico de la lepra. |
US20190328869A1 (en) | 2016-10-10 | 2019-10-31 | Transgene Sa | Immunotherapeutic product and mdsc modulator combination therapy |
CN106546737A (zh) * | 2016-10-24 | 2017-03-29 | 广州迪澳医疗科技有限公司 | 一种体外检测活动性结核的方法 |
CN107236023B (zh) * | 2017-05-12 | 2021-05-07 | 苏州创澜生物科技有限公司 | 一种用于检测结核感染的抗原组合物及其应用 |
EP3697806A4 (en) | 2017-10-17 | 2021-10-27 | International AIDS Vaccine Initiative, Inc. | TUBERCULOSIS ANTIGEN CASSETTES |
WO2019210282A2 (en) * | 2018-04-26 | 2019-10-31 | Children's National Medical Center | Mycobacterial antigen compositions and methods of use |
CN109536431A (zh) * | 2018-12-04 | 2019-03-29 | 江苏省农业科学院 | 复合生化复苏因子组合物及其应用 |
KR102135328B1 (ko) * | 2018-12-19 | 2020-07-17 | 대한민국 | 결핵 2가 항원을 발현하는 약독화된 재조합 백시니아 바이러스 및 이를 포함하는 결핵 예방용 조성물 |
KR102157770B1 (ko) * | 2019-01-11 | 2020-09-18 | 주식회사 파이지노믹스 | 가축의 결핵 진단을 위한 항원 펩타이드 조성물 및 이의 용도 |
CN109970183B (zh) * | 2019-03-31 | 2021-01-15 | 浙江大学 | 一种复苏促进因子在印染废水处理中的应用及处理方法 |
BR112021025172A2 (pt) * | 2019-06-14 | 2022-01-25 | Statens Seruminstitut | Proteínas de fusão para vacinas de tuberculose |
CN110590958B (zh) * | 2019-09-11 | 2021-04-13 | 中国人民解放军总医院第八医学中心 | 一种串联多肽及其在抗结核分枝杆菌的免疫保护中的应用 |
CN110590957B (zh) * | 2019-09-11 | 2021-06-01 | 中国人民解放军总医院第八医学中心 | 一种融合蛋白及其在抗结核分枝杆菌的免疫保护中的应用 |
RU2724896C1 (ru) * | 2019-11-14 | 2020-06-26 | федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации | Полиантигенная вакцина для профилактики и вспомогательного лечения туберкулеза |
CN111443208B (zh) * | 2020-03-23 | 2024-01-19 | 中国医学科学院北京协和医院 | 鉴别活动性结核病和潜伏性结核病的组合物 |
WO2024023790A1 (en) * | 2022-07-29 | 2024-02-01 | University Of Cape Town | Vaccine constructs comprising tuberculosis antigens |
WO2024028445A1 (en) * | 2022-08-03 | 2024-02-08 | BioNTech SE | Rna for preventing or treating tuberculosis |
WO2024027910A1 (en) * | 2022-08-03 | 2024-02-08 | BioNTech SE | Rna for preventing or treating tuberculosis |
CN116162141B (zh) * | 2022-11-30 | 2024-04-12 | 中国疾病预防控制中心传染病预防控制所 | 一种结核分枝杆菌抗原epcra013及其应用 |
CN116041543B (zh) * | 2022-12-07 | 2023-12-26 | 中国疾病预防控制中心传染病预防控制所 | 结核分枝杆菌多抗原融合蛋白及其编码基因和应用 |
CN116063418B (zh) * | 2022-12-08 | 2024-04-12 | 中国疾病预防控制中心传染病预防控制所 | 结核分枝杆菌抗原组合物epdpa015及其制备方法与应用 |
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EP1711518B1 (en) | 2004-01-23 | 2009-11-18 | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. | Chimpanzee adenovirus vaccine carriers |
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BRPI0606165A2 (pt) | 2005-01-05 | 2009-06-02 | Isis Innovation | método de indução de uma resposta imunológica de célula t de memória contra pelo menos um antìgeno em um paciente humano, uso de uma composição imunogênica que compreende um vetor de vìrus de infecção virulenta não-replicante ou emparelhado de replicação que expressa o produto de tradução de um gene de ag85a micobacterial, uso de um antìgeno na manufatura de um medicamento para o tratamento de uma doença em um paciente mediante a indução de uma resposta imunológica de célula t de memória central e vacina vetorada |
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CN100999550B (zh) * | 2006-01-10 | 2010-10-06 | 中国人民解放军第三○九医院 | 结核分枝杆菌融合蛋白及其应用 |
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MX351247B (es) * | 2007-04-04 | 2017-10-05 | Infectious Disease Res Institute Star | Composiciones inmunogenicas que comprenden polipeptidos de mycobacterium tuberculosis y fusiones de los mismos. |
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BRPI0811787B1 (pt) | 2007-07-03 | 2018-10-09 | Transgene Sa | usos de uma célula imortalizada e processo para imortalizar uma célula aviária |
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WO2014009438A2 (en) * | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterial antigen vaccine |
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EP4176897A1 (en) * | 2013-06-25 | 2023-05-10 | International AIDS Vaccine Initiative, Inc. | Tuberculosis compositions and methods of using the same |
TWI654200B (zh) * | 2013-08-30 | 2019-03-21 | 環球免疫公司 | 治療或預防結核病的組合物及方法 |
CN106103471B (zh) * | 2014-01-09 | 2020-01-07 | 特兰斯吉恩股份有限公司 | 异源寡聚分枝杆菌抗原的融合 |
GB201400819D0 (en) * | 2014-01-17 | 2014-03-05 | Sec Dep For Health The | Mycobacterial antigen composition |
BR112016023778A2 (pt) * | 2014-04-24 | 2017-10-17 | Statens Seruminstitut | proteína de fusão ou coquetel antígeno, uso de uma proteína de fusão ou coquetel antígeno, vacina, e método para a imunização de um animal, incluindo um ser humano, contra a tuberculose causada por micobactérias virulentas |
MX2017003017A (es) * | 2014-09-09 | 2018-02-19 | Virginia Tech Intellectual Properties Inc | Vacuna multivalente de brucella para la proteccion contra infecciones micobacterianas y metodos para su uso. |
CN109890411A (zh) * | 2016-06-16 | 2019-06-14 | 国际艾滋病疫苗行动组织公司 | 结核病组合物和治疗或预防结核病的方法 |
US11091775B2 (en) * | 2016-06-22 | 2021-08-17 | Oregon Health And Science University | Recombinant cytomegalovirus vectors as vaccines for tuberculosis |
-
2013
- 2013-07-10 WO PCT/EP2013/064624 patent/WO2014009438A2/en active Application Filing
- 2013-07-10 JP JP2015520979A patent/JP6333814B2/ja not_active Expired - Fee Related
- 2013-07-10 SG SG11201500171YA patent/SG11201500171YA/en unknown
- 2013-07-10 TW TW102124693A patent/TWI638829B/zh not_active IP Right Cessation
- 2013-07-10 MX MX2015000449A patent/MX366206B/es active IP Right Grant
- 2013-07-10 EA EA201590184A patent/EA029492B1/ru not_active IP Right Cessation
- 2013-07-10 CN CN201380046981.7A patent/CN104640564B/zh not_active Expired - Fee Related
- 2013-07-10 EP EP13735275.3A patent/EP2872172B1/en not_active Not-in-force
- 2013-07-10 MY MYPI2015000055A patent/MY173004A/en unknown
- 2013-07-10 KR KR1020157003607A patent/KR20150058152A/ko active IP Right Grant
- 2013-07-10 US US14/413,565 patent/US10357555B2/en not_active Expired - Fee Related
- 2013-07-10 CA CA2878800A patent/CA2878800A1/en not_active Abandoned
- 2013-07-10 BR BR112015000530A patent/BR112015000530A2/pt not_active Application Discontinuation
- 2013-10-07 UA UAA201501068A patent/UA119228C2/uk unknown
-
2015
- 2015-01-11 IL IL236650A patent/IL236650B/en not_active IP Right Cessation
- 2015-02-03 ZA ZA2015/00784A patent/ZA201500784B/en unknown
- 2015-09-01 HK HK15108554.4A patent/HK1207962A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SG11201500171YA (en) | 2015-02-27 |
CN104640564A (zh) | 2015-05-20 |
IL236650A0 (en) | 2015-02-26 |
UA119228C2 (uk) | 2019-05-27 |
MX2015000449A (es) | 2015-07-14 |
WO2014009438A2 (en) | 2014-01-16 |
TWI638829B (zh) | 2018-10-21 |
IL236650B (en) | 2019-09-26 |
EP2872172A2 (en) | 2015-05-20 |
ZA201500784B (en) | 2020-07-29 |
CA2878800A1 (en) | 2014-01-16 |
JP2015524794A (ja) | 2015-08-27 |
TW201408691A (zh) | 2014-03-01 |
HK1207962A1 (en) | 2016-02-19 |
MY173004A (en) | 2019-12-18 |
EA029492B1 (ru) | 2018-04-30 |
KR20150058152A (ko) | 2015-05-28 |
EA201590184A1 (ru) | 2015-06-30 |
US20150165014A1 (en) | 2015-06-18 |
EP2872172B1 (en) | 2018-11-14 |
CN104640564B (zh) | 2020-08-04 |
JP6333814B2 (ja) | 2018-05-30 |
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MX366206B (es) | 2019-07-02 |
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