ATE517855T1 - Antikörper gegen chemotaktische monozytenproteine - Google Patents
Antikörper gegen chemotaktische monozytenproteineInfo
- Publication number
- ATE517855T1 ATE517855T1 AT02792310T AT02792310T ATE517855T1 AT E517855 T1 ATE517855 T1 AT E517855T1 AT 02792310 T AT02792310 T AT 02792310T AT 02792310 T AT02792310 T AT 02792310T AT E517855 T1 ATE517855 T1 AT E517855T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- monocyte proteins
- chemotactic
- chemotactic monocyte
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34339101P | 2001-11-30 | 2001-11-30 | |
| US38327702P | 2002-05-24 | 2002-05-24 | |
| US40046902P | 2002-08-01 | 2002-08-01 | |
| PCT/US2002/038229 WO2003048083A2 (en) | 2001-11-30 | 2002-11-27 | Antibodies against monocyte chemotactic proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE517855T1 true ATE517855T1 (de) | 2011-08-15 |
Family
ID=27407563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02792310T ATE517855T1 (de) | 2001-11-30 | 2002-11-27 | Antikörper gegen chemotaktische monozytenproteine |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US7405277B2 (de) |
| EP (3) | EP1461300B1 (de) |
| AR (1) | AR037456A1 (de) |
| AT (1) | ATE517855T1 (de) |
| AU (1) | AU2002357770B2 (de) |
| CA (1) | CA2468733C (de) |
| DK (1) | DK1461300T3 (de) |
| WO (1) | WO2003048083A2 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1461300T3 (da) * | 2001-11-30 | 2011-10-24 | Biogen Idec Inc | Antistoffer mod kemotaktiske monocytproteiner |
| WO2004016767A2 (en) * | 2002-08-19 | 2004-02-26 | The President And Fellows Of Harvard College | Evolving new molecular function |
| GB0228832D0 (en) * | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
| WO2004045525A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
| WO2004050836A2 (en) * | 2002-11-27 | 2004-06-17 | Biogen Idec Ma Inc. | Humanized antibodies against monocyte chemotactic proteins |
| GB0321997D0 (en) * | 2003-09-19 | 2003-10-22 | Novartis Ag | Organic compound |
| EP1684703A4 (de) * | 2003-11-05 | 2008-10-01 | Centocor Inc | Verfahren und zusammensetzungen zur behandlung von erkrankungen im zusammenhang mit mcp-1 |
| ATE447020T1 (de) * | 2004-03-22 | 2009-11-15 | Nuevolution As | Ligationscodierung unter verwendung von oligonukleotidbausteinen |
| AU2011265315B2 (en) * | 2004-05-12 | 2014-08-28 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods related to the treatment of neurodegenerative and inflammatory conditions |
| CA2566445C (en) | 2004-05-12 | 2016-02-02 | The Government Of The United States As Represented By The Secretary, Department Of Health And Human Services | Methods related to the treatment of neurodegenerative and inflammatory conditions |
| EP1784425A4 (de) * | 2004-06-30 | 2009-02-18 | Centocor Inc | Anti-mcp-1-antikörper, zusammensetzungen, verfahren und verwendung |
| PE20110071A1 (es) * | 2005-05-19 | 2011-01-31 | Centocor Inc | Anticuerpos anti-mcp-1, composiciones y metodos |
| US8114964B2 (en) | 2005-05-19 | 2012-02-14 | Centocor, Inc. | Anti-MCP-1 antibodies, compositions, methods and uses |
| US20070099239A1 (en) * | 2005-06-24 | 2007-05-03 | Raymond Tabibiazar | Methods and compositions for diagnosis and monitoring of atherosclerotic cardiovascular disease |
| US20100267145A1 (en) * | 2006-06-05 | 2010-10-21 | Hiroshima University | Immunocompetent cell having anti-cd38 antibody on its cell surface |
| US20080076120A1 (en) * | 2006-09-14 | 2008-03-27 | Millennium Pharmaceuticals, Inc. | Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders |
| US7608693B2 (en) | 2006-10-02 | 2009-10-27 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human IL-4 receptor |
| WO2008054606A2 (en) * | 2006-10-02 | 2008-05-08 | Regeneron Pharmaceuticals, Inc. | High affinity human antibodies to human il-4 receptor |
| JP5403752B2 (ja) * | 2007-06-22 | 2014-01-29 | 北海道公立大学法人 札幌医科大学 | 移植片対宿主疾患の検査および治療方法 |
| US8710191B2 (en) | 2008-08-18 | 2014-04-29 | Pfizer Inc. | Antibodies to CCR2 |
| CA2779683A1 (en) * | 2009-11-10 | 2011-05-19 | Amgen Inc. | Anti-c-mpl antibodies |
| JP5786020B2 (ja) * | 2010-04-16 | 2015-09-30 | アボットジャパン株式会社 | 関節リウマチを診断する方法および試薬 |
| GB201205739D0 (en) * | 2012-03-30 | 2012-05-16 | Ucl Business Plc | Treatment of acute inflammation in the respiratory tract |
| IN2014DN09951A (de) * | 2012-05-22 | 2015-08-14 | Shire Human Genetic Therapies | |
| WO2014031610A1 (en) | 2012-08-21 | 2014-02-27 | Sanofi | Methods for treating or preventing asthma by administering an il-4r antagonist |
| HRP20181227T1 (hr) | 2012-09-07 | 2018-10-05 | Regeneron Pharmaceuticals, Inc. | Metode za liječenje atopijskog dermatitisa primjenom antagonista il-4r |
| EA201591993A1 (ru) * | 2013-05-23 | 2016-05-31 | Шир Хьюман Дженетик Терапис, Инк. | Лечение склеродермии с применением комбинированной терапии антителами анти-ccl2 и анти-loxl2 |
| TWI755763B (zh) | 2013-06-04 | 2022-02-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| TWI634900B (zh) | 2013-07-11 | 2018-09-11 | 再生元醫藥公司 | 藉由投與il-4r抑制劑治療嗜酸性食道炎的方法 |
| RU2704999C2 (ru) | 2014-02-28 | 2019-11-01 | Ридженерон Фармасьютикалз, Инк. | Способ лечения кожной инфекции путем введения антагониста il-4r |
| US10066017B2 (en) | 2014-11-14 | 2018-09-04 | Sanofi Biotechnology | Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist |
| ES2764840T3 (es) | 2015-01-28 | 2020-06-04 | Univ Bordeaux | Uso de plerixafor para tratar y/o prevenir exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica |
| JP6947372B2 (ja) * | 2015-05-26 | 2021-10-13 | 学校法人東京薬科大学 | 炎症性腸疾患を抑制する抗体および該抗体を含む医薬組成物 |
| CN109789196B (zh) | 2016-09-01 | 2024-03-19 | 瑞泽恩制药公司 | 用于通过施用il-4r拮抗剂来预防或治疗变态反应的方法 |
| WO2019028367A1 (en) | 2017-08-04 | 2019-02-07 | Regeneron Pharmaceuticals, Inc. | METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES |
| PT3515465T (pt) | 2017-08-18 | 2024-03-04 | Regeneron Pharma | Métodos para o tratamento de uma dermatite atópica grave mediante a administração de um inibidor de il-4r |
| PL3703818T3 (pl) | 2017-10-30 | 2024-03-25 | Sanofi Biotechnology | Antagonista IL-4R do zastosowania w sposobie leczenia lub zapobiegania astmie |
| EP3793597A1 (de) | 2018-05-13 | 2021-03-24 | Regeneron Pharmaceuticals, Inc. | Verfahren zur behandlung atopischer dermatitis durch verabreichung eines il-4r-inhibitors |
| WO2020074704A1 (en) * | 2018-10-11 | 2020-04-16 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Means and methods for detecting soy allergens |
| MA55372A (fr) | 2019-03-21 | 2022-01-26 | Regeneron Pharma | Combinaison d'inhibiteurs de la voie il-4/il-13 et d'ablation de plasmocytes pour traiter une allergie |
| MX2021012163A (es) | 2019-04-17 | 2022-01-31 | Univ Hiroshima | Agente terapeutico para cancer urologico que se caracteriza por ser administrado con un inhibidor de il-6 y un inhibidor de ccr2 en combinacion. |
| JP7592064B2 (ja) | 2019-07-16 | 2024-11-29 | サノフィ・バイオテクノロジー | Il-4rアンタゴニストを投与することにより喘息を治療するまたは予防するための方法 |
| AU2020326713A1 (en) | 2019-08-05 | 2022-02-17 | Regeneron Pharmaceuticals, Inc. | Methods for treating atopic dermatitis by administering an il-4r antagonist |
| CN114173819A (zh) | 2019-08-05 | 2022-03-11 | 瑞泽恩制药公司 | 通过施用il-4r拮抗剂治疗过敏和增强过敏原特异性免疫疗法的方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4704362A (en) | 1977-11-08 | 1987-11-03 | Genentech, Inc. | Recombinant cloning vehicle microbial polypeptide expression |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0154316B1 (de) | 1984-03-06 | 1989-09-13 | Takeda Chemical Industries, Ltd. | Chemisch modifizierte Lymphokine und Verfahren zu ihrer Herstellung |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (de) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimäre Rezeptoren durch Verbindung und Expression von DNS |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| EP0832981A1 (de) | 1987-02-17 | 1998-04-01 | Pharming B.V. | DNA-Sequenzen die Proteine zwecks effizienter Abscheidung zur Milchdrüse leiten |
| JP2989002B2 (ja) | 1988-12-22 | 1999-12-13 | キリン―アムジエン・インコーポレーテツド | 化学修飾顆粒球コロニー刺激因子 |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5633076A (en) | 1989-12-01 | 1997-05-27 | Pharming Bv | Method of producing a transgenic bovine or transgenic bovine embryo |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| EP0940468A1 (de) | 1991-06-14 | 1999-09-08 | Genentech, Inc. | Änderliches Gebiet einer humanisierter Antikörper |
| JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化b−b10 |
| US5714350A (en) | 1992-03-09 | 1998-02-03 | Protein Design Labs, Inc. | Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region |
| US5510264A (en) * | 1993-09-28 | 1996-04-23 | Insight Biotech Inc. | Antibodies which bind meningitis related homologous antigenic sequences |
| US5827690A (en) | 1993-12-20 | 1998-10-27 | Genzyme Transgenics Corporatiion | Transgenic production of antibodies in milk |
| GB9424449D0 (en) | 1994-12-02 | 1995-01-18 | Wellcome Found | Antibodies |
| JPH0967399A (ja) | 1995-08-30 | 1997-03-11 | Mitsui Toatsu Chem Inc | 抗mcp−1ヒトモノクローナル抗体 |
| SE9600820D0 (sv) * | 1996-03-01 | 1996-03-01 | Pharmacia Ab | Antibodies and their use |
| US6312689B1 (en) | 1998-07-23 | 2001-11-06 | Millennium Pharmaceuticals, Inc. | Anti-CCR2 antibodies and methods of use therefor |
| MXPA02007449A (es) | 2000-02-03 | 2003-04-14 | Millennium Pharm Inc | Anticuerpos anti-ccr2 humanizados y metodos para el uso de los mismos. |
| WO2001089565A1 (en) | 2000-05-19 | 2001-11-29 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for reducing tumor growth and metastasis by inhibiting mcp-1 activity |
| AU2001258836A1 (en) | 2000-05-26 | 2001-12-03 | Kensuke Egashira | Preventives and remedies for pulmonary hypertension |
| GB0016138D0 (en) | 2000-06-30 | 2000-08-23 | Novartis Ag | Organic compounds |
| DK1461300T3 (da) | 2001-11-30 | 2011-10-24 | Biogen Idec Inc | Antistoffer mod kemotaktiske monocytproteiner |
| WO2004050836A2 (en) * | 2002-11-27 | 2004-06-17 | Biogen Idec Ma Inc. | Humanized antibodies against monocyte chemotactic proteins |
| IT1395574B1 (it) | 2009-09-14 | 2012-10-16 | Guala Dispensing Spa | Dispositivo di erogazione |
-
2002
- 2002-11-27 DK DK02792310.1T patent/DK1461300T3/da active
- 2002-11-27 WO PCT/US2002/038229 patent/WO2003048083A2/en not_active Ceased
- 2002-11-27 AR ARP020104579A patent/AR037456A1/es not_active Application Discontinuation
- 2002-11-27 EP EP02792310A patent/EP1461300B1/de not_active Expired - Lifetime
- 2002-11-27 AT AT02792310T patent/ATE517855T1/de not_active IP Right Cessation
- 2002-11-27 AU AU2002357770A patent/AU2002357770B2/en not_active Expired
- 2002-11-27 CA CA2468733A patent/CA2468733C/en not_active Expired - Lifetime
- 2002-11-27 EP EP10180666.9A patent/EP2298717B1/de not_active Expired - Lifetime
- 2002-11-27 EP EP15185855.2A patent/EP2990394A1/de not_active Withdrawn
-
2004
- 2004-05-27 US US10/855,013 patent/US7405277B2/en not_active Expired - Lifetime
-
2008
- 2008-07-11 US US12/171,791 patent/US7632501B2/en not_active Expired - Lifetime
-
2009
- 2009-11-04 US US12/612,087 patent/US7972597B2/en not_active Expired - Lifetime
-
2011
- 2011-06-09 US US13/156,959 patent/US8431125B2/en not_active Expired - Lifetime
-
2013
- 2013-04-16 US US13/863,574 patent/US9096665B2/en not_active Expired - Lifetime
-
2015
- 2015-06-22 US US14/746,555 patent/US20160185846A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1461300A4 (de) | 2005-12-28 |
| US20160185846A1 (en) | 2016-06-30 |
| US20120039873A1 (en) | 2012-02-16 |
| US20050025768A1 (en) | 2005-02-03 |
| US20100166757A1 (en) | 2010-07-01 |
| AU2002357770A1 (en) | 2003-06-17 |
| AU2002357770B2 (en) | 2008-07-31 |
| CA2468733A1 (en) | 2003-06-12 |
| EP2990394A1 (de) | 2016-03-02 |
| EP2298717B1 (de) | 2015-10-28 |
| US7972597B2 (en) | 2011-07-05 |
| AR037456A1 (es) | 2004-11-10 |
| EP1461300A2 (de) | 2004-09-29 |
| EP1461300B1 (de) | 2011-07-27 |
| CA2468733C (en) | 2013-06-11 |
| US9096665B2 (en) | 2015-08-04 |
| US7405277B2 (en) | 2008-07-29 |
| WO2003048083A2 (en) | 2003-06-12 |
| DK1461300T3 (da) | 2011-10-24 |
| US20140178382A1 (en) | 2014-06-26 |
| US8431125B2 (en) | 2013-04-30 |
| WO2003048083A3 (en) | 2004-01-15 |
| US7632501B2 (en) | 2009-12-15 |
| US20090017028A1 (en) | 2009-01-15 |
| EP2298717A1 (de) | 2011-03-23 |
| HK1155720A1 (en) | 2012-05-25 |
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