MX2010002734A - Derivados de 1-amino-alquilciclohexano para el tratamiento y prevencion de perdida auditiva. - Google Patents
Derivados de 1-amino-alquilciclohexano para el tratamiento y prevencion de perdida auditiva.Info
- Publication number
- MX2010002734A MX2010002734A MX2010002734A MX2010002734A MX2010002734A MX 2010002734 A MX2010002734 A MX 2010002734A MX 2010002734 A MX2010002734 A MX 2010002734A MX 2010002734 A MX2010002734 A MX 2010002734A MX 2010002734 A MX2010002734 A MX 2010002734A
- Authority
- MX
- Mexico
- Prior art keywords
- amino
- treatment
- hearing loss
- prevention
- alkylcyclohexane derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Percussion Or Vibration Massage (AREA)
Abstract
La presente invenci?n se refiere al tratamiento de un individuo diagnosticado con p?rdida auditiva, que comprende administrar al individuo una cantidad efectiva de un derivado de 1-amino-alquilciclohexano.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99339607P | 2007-09-12 | 2007-09-12 | |
EP07253630 | 2007-09-12 | ||
US6708308P | 2008-02-25 | 2008-02-25 | |
US6693108P | 2008-02-25 | 2008-02-25 | |
US6702608P | 2008-02-25 | 2008-02-25 | |
EP08004776 | 2008-03-14 | ||
EP08004778 | 2008-03-14 | ||
EP08004777 | 2008-03-14 | ||
PCT/EP2008/007419 WO2009033650A1 (en) | 2007-09-12 | 2008-09-10 | 1-amino-alkylcyclohexane derivatives for the treatment and prevention of hearing loss |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010002734A true MX2010002734A (es) | 2010-04-01 |
Family
ID=40451596
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010002733A MX2010002733A (es) | 2007-09-12 | 2008-09-10 | Terapia de intervalo para el tratamiento de tinnitus. |
MX2010002734A MX2010002734A (es) | 2007-09-12 | 2008-09-10 | Derivados de 1-amino-alquilciclohexano para el tratamiento y prevencion de perdida auditiva. |
MX2010002736A MX2010002736A (es) | 2007-09-12 | 2008-09-10 | Derivados de 1-amino-alquilciclohexano para el tratamiento de tinnitus coclear. |
MX2010002735A MX2010002735A (es) | 2007-09-12 | 2008-09-10 | Envase de titulacion para neramexano y su uso en el tratamiento de un trastorno del oido interno. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010002733A MX2010002733A (es) | 2007-09-12 | 2008-09-10 | Terapia de intervalo para el tratamiento de tinnitus. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010002736A MX2010002736A (es) | 2007-09-12 | 2008-09-10 | Derivados de 1-amino-alquilciclohexano para el tratamiento de tinnitus coclear. |
MX2010002735A MX2010002735A (es) | 2007-09-12 | 2008-09-10 | Envase de titulacion para neramexano y su uso en el tratamiento de un trastorno del oido interno. |
Country Status (21)
Country | Link |
---|---|
US (6) | US20110086916A1 (es) |
EP (6) | EP2200598A1 (es) |
JP (6) | JP5613053B2 (es) |
KR (4) | KR20100052556A (es) |
CN (4) | CN101801366A (es) |
AR (3) | AR071728A1 (es) |
AT (1) | ATE532507T1 (es) |
AU (4) | AU2008298017B2 (es) |
BR (2) | BRPI0816690A2 (es) |
CA (4) | CA2699209A1 (es) |
DK (1) | DK2200600T3 (es) |
ES (5) | ES2510565T3 (es) |
HR (1) | HRP20120046T1 (es) |
MX (4) | MX2010002733A (es) |
PL (1) | PL2200600T3 (es) |
PT (1) | PT2200600E (es) |
RU (1) | RU2011137131A (es) |
SI (1) | SI2200600T1 (es) |
TW (3) | TW200918042A (es) |
WO (4) | WO2009033650A1 (es) |
ZA (4) | ZA201001262B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2200600T3 (pl) * | 2007-09-12 | 2012-04-30 | Merz Pharma Gmbh & Co Kgaa | Nerameksan do zastosowania w leczeniu podostrego szumu usznego |
US20110294890A1 (en) * | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
WO2011160839A1 (en) | 2010-06-24 | 2011-12-29 | Merz Pharma Gmbh & Co. Kgaa | Neramexane multiple unit dosage form |
US20130296427A1 (en) * | 2011-01-20 | 2013-11-07 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss |
CA2904055A1 (en) * | 2013-03-06 | 2014-09-12 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure |
CN106535883A (zh) * | 2014-04-28 | 2017-03-22 | 杏林制药株式会社 | 耳鸣患者的治疗用药剂 |
EP3138559A4 (en) * | 2014-04-28 | 2017-10-25 | Kyorin Pharmaceutical Co., Ltd. | Drug for treatment of tinnitus patients |
CA2999467C (en) | 2014-10-23 | 2023-10-10 | Arena Pharmaceuticals, Inc. | Method of treating conditions related to the pgi2 receptor |
PL3297628T3 (pl) * | 2015-05-18 | 2021-12-06 | Sensorion | Azasetron do stosowania w leczeniu niedosłuchu |
KR101893604B1 (ko) | 2015-08-27 | 2018-08-30 | 경희대학교 산학협력단 | 칸디다 유틸리스 추출물을 포함하는 난청의 예방 또는 치료용 조성물 |
CN105924362B (zh) * | 2016-02-05 | 2018-08-17 | 上海龙翔生物医药开发有限公司 | 芳香环丙基胺类化合物、其药学上可接受的盐、其制备方法及其用途 |
CN110582271B (zh) | 2017-03-01 | 2022-06-14 | 阿瑞那制药公司 | 包含pgi2受体激动剂的组合物及其制备方法 |
KR102268893B1 (ko) | 2020-01-16 | 2021-06-24 | 경북대학교 산학협력단 | 림노트릭스 속 knua002 균주를 포함하는 난청의 예방 또는 치료용 조성물 |
CN111477199B (zh) * | 2020-04-02 | 2021-11-30 | 北京瑞迪欧文化传播有限责任公司 | 一种嵌入式音乐控制系统 |
Family Cites Families (34)
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US5811128A (en) | 1986-10-24 | 1998-09-22 | Southern Research Institute | Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor |
US4849222A (en) | 1987-03-24 | 1989-07-18 | The Procter & Gamble Company | Mixtures for treating hypercholesterolemia |
JP2670680B2 (ja) | 1988-02-24 | 1997-10-29 | 株式会社ビーエムジー | 生理活性物質含有ポリ乳酸系微小球およびその製造法 |
US5288502A (en) | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
CA2172509C (en) | 1993-10-22 | 2010-08-24 | Jeffrey L. Cleland | Methods and compositions for microencapsulation of antigens for use as vaccines |
DE19528388A1 (de) * | 1995-08-02 | 1997-02-06 | Hans Peter Prof Dr Med Zenner | Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs |
AU4424697A (en) * | 1996-09-11 | 1998-04-02 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | The use of functional n-methyl-d-aspartate antagonists to ameliorate or prevent aminoglycoside-induced ototoxicity |
EP1009732B1 (en) * | 1997-06-30 | 2003-05-21 | MERZ + CO. GmbH & Co. | 1-amino-alkylcyclohexane nmda receptor antagonists |
US6071966A (en) * | 1997-06-30 | 2000-06-06 | Merz + Co. Gmbh & Co. | 1-amino-alkylcyclohexane NMDA receptor antagonists |
JP2003531187A (ja) * | 2000-04-26 | 2003-10-21 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | サブタイプ選択的nmda受容体アンタゴニストとしてのシクロヘキシルアミン誘導体 |
DE10048969A1 (de) * | 2000-08-23 | 2002-03-14 | Mueller Schwefe Gerhard | Verwendung von Flupirtin zur Tinnitusbehandlung |
US20030236288A1 (en) * | 2002-02-28 | 2003-12-25 | Karl Schoenafinger | Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase |
JP2004021734A (ja) | 2002-06-18 | 2004-01-22 | Nokia Corp | キーパッドおよびキーパッドシステム |
US7086532B2 (en) * | 2003-07-16 | 2006-08-08 | Allergan, Inc. | Titration/compliance pack with increasing doses |
EP1545551A4 (en) * | 2002-09-06 | 2008-10-22 | Durect Corp | DISTRIBUTION OF MODULATORS OF THE GLUTAMAT-MEDIATED NEUROTRANSMISSION TO THE INNER EAR |
DE10252665A1 (de) | 2002-11-11 | 2004-06-03 | Grünenthal GmbH | 4-Aminomethyl-1-aryl-cyclohexylamin-Derivate |
EA010430B1 (ru) * | 2003-05-27 | 2008-08-29 | Форест Лэборэтериз, Инк. | Сочетание антагониста nmda-рецептора и селективного ингибитора обратного захвата серотонина для лечения депрессии и других психических расстройств |
AR046314A1 (es) * | 2003-11-05 | 2005-11-30 | Merz Pharma Gmbh & Co Kgaa | Composiciones que comprenden ciclohexilaminas y aminoadamantanos |
US20060002999A1 (en) | 2004-06-17 | 2006-01-05 | Forest Laboratories, Inc. | Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane |
KR20090033410A (ko) | 2004-06-17 | 2009-04-02 | 메르츠 파마 게엠베하 운트 코. 카가아 | 메만타인 또는 네라멕산의 직접 압축으로 제조된 마실수 있는 즉시 방출형 제제 |
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US20060264897A1 (en) * | 2005-01-24 | 2006-11-23 | Neurosystec Corporation | Apparatus and method for delivering therapeutic and/or other agents to the inner ear and to other tissues |
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CN1896729A (zh) | 2005-07-15 | 2007-01-17 | 复旦大学附属中山医院 | 纳米药物自组装双稳态量子线阵列及其制备方法 |
US20070141148A1 (en) * | 2005-11-30 | 2007-06-21 | Merz Pharma Gmbh & Co. Kgaa | Neramexane MR matrix tablet |
TW200819458A (en) * | 2006-06-23 | 2008-05-01 | Merz Pharma Gmbh & Co Kgaa | Metabotropic glutamate receptor modulators |
PL2200600T3 (pl) * | 2007-09-12 | 2012-04-30 | Merz Pharma Gmbh & Co Kgaa | Nerameksan do zastosowania w leczeniu podostrego szumu usznego |
TW201010691A (en) * | 2008-06-12 | 2010-03-16 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders |
TW201006463A (en) * | 2008-06-26 | 2010-02-16 | Merz Pharma Gmbh & Co Kgaa | Pharmaceutical compositions comprising aminocyclohexane derivatives |
AU2009291244A1 (en) * | 2008-09-10 | 2010-03-18 | Merz Pharma Gmbh & Co. Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of cognitive impairment in tinnitus |
US20110294890A1 (en) * | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
US20130296427A1 (en) * | 2011-01-20 | 2013-11-07 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss |
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2008
- 2008-09-10 PL PL08801987T patent/PL2200600T3/pl unknown
- 2008-09-10 CN CN200880106973A patent/CN101801366A/zh active Pending
- 2008-09-10 EP EP08801984A patent/EP2200598A1/en not_active Withdrawn
- 2008-09-10 JP JP2010524392A patent/JP5613053B2/ja not_active Expired - Fee Related
- 2008-09-10 CN CN200880106975A patent/CN101795679A/zh active Pending
- 2008-09-10 MX MX2010002733A patent/MX2010002733A/es not_active Application Discontinuation
- 2008-09-10 US US12/733,577 patent/US20110086916A1/en not_active Abandoned
- 2008-09-10 WO PCT/EP2008/007419 patent/WO2009033650A1/en active Application Filing
- 2008-09-10 EP EP11005567.0A patent/EP2386299B1/en active Active
- 2008-09-10 US US12/733,646 patent/US9498450B2/en not_active Expired - Fee Related
- 2008-09-10 CA CA2699209A patent/CA2699209A1/en not_active Abandoned
- 2008-09-10 CA CA2699213A patent/CA2699213A1/en not_active Abandoned
- 2008-09-10 CA CA2699210A patent/CA2699210A1/en not_active Abandoned
- 2008-09-10 ES ES08801986.4T patent/ES2510565T3/es active Active
- 2008-09-10 US US12/733,582 patent/US9468610B2/en not_active Expired - Fee Related
- 2008-09-10 EP EP08801986.4A patent/EP2203163B1/en active Active
- 2008-09-10 AR ARP080103938A patent/AR071728A1/es not_active Application Discontinuation
- 2008-09-10 WO PCT/EP2008/007420 patent/WO2009033651A1/en active Application Filing
- 2008-09-10 EP EP08801987A patent/EP2200600B1/en active Active
- 2008-09-10 AU AU2008298017A patent/AU2008298017B2/en not_active Ceased
- 2008-09-10 EP EP08801985.6A patent/EP2200599B1/en active Active
- 2008-09-10 KR KR1020107007786A patent/KR20100052556A/ko not_active Application Discontinuation
- 2008-09-10 PT PT08801987T patent/PT2200600E/pt unknown
- 2008-09-10 AT AT08801987T patent/ATE532507T1/de active
- 2008-09-10 ES ES11005567.0T patent/ES2596262T3/es active Active
- 2008-09-10 TW TW097134699A patent/TW200918042A/zh unknown
- 2008-09-10 CA CA2699207A patent/CA2699207A1/en not_active Abandoned
- 2008-09-10 ES ES08801985.6T patent/ES2604945T3/es active Active
- 2008-09-10 JP JP2010524394A patent/JP5563460B2/ja not_active Expired - Fee Related
- 2008-09-10 WO PCT/EP2008/007421 patent/WO2009033652A1/en active Application Filing
- 2008-09-10 BR BRPI0816690A patent/BRPI0816690A2/pt not_active IP Right Cessation
- 2008-09-10 MX MX2010002734A patent/MX2010002734A/es not_active Application Discontinuation
- 2008-09-10 CN CN200880106925A patent/CN101801365A/zh active Pending
- 2008-09-10 BR BRPI0816712A patent/BRPI0816712A2/pt not_active IP Right Cessation
- 2008-09-10 CN CN200880106404A patent/CN101835469A/zh active Pending
- 2008-09-10 MX MX2010002736A patent/MX2010002736A/es not_active Application Discontinuation
- 2008-09-10 SI SI200830530T patent/SI2200600T1/sl unknown
- 2008-09-10 ES ES12006826.7T patent/ES2562709T3/es active Active
- 2008-09-10 KR KR1020107007787A patent/KR20100052557A/ko not_active Application Discontinuation
- 2008-09-10 TW TW097134705A patent/TW200922544A/zh unknown
- 2008-09-10 WO PCT/EP2008/007418 patent/WO2009033649A1/en active Application Filing
- 2008-09-10 US US12/733,645 patent/US8877814B2/en not_active Expired - Fee Related
- 2008-09-10 MX MX2010002735A patent/MX2010002735A/es unknown
- 2008-09-10 KR KR1020107007793A patent/KR20100052558A/ko not_active Application Discontinuation
- 2008-09-10 JP JP2010524393A patent/JP5612473B2/ja not_active Expired - Fee Related
- 2008-09-10 ES ES08801987T patent/ES2377253T3/es active Active
- 2008-09-10 AU AU2008298018A patent/AU2008298018C1/en not_active Ceased
- 2008-09-10 JP JP2010524395A patent/JP5563461B2/ja not_active Expired - Fee Related
- 2008-09-10 AR ARP080103936A patent/AR070025A1/es not_active Application Discontinuation
- 2008-09-10 KR KR1020107007795A patent/KR20100052559A/ko not_active Application Discontinuation
- 2008-09-10 AU AU2008298016A patent/AU2008298016B2/en not_active Ceased
- 2008-09-10 TW TW097134701A patent/TW200927087A/zh unknown
- 2008-09-10 AU AU2008298015A patent/AU2008298015B2/en not_active Ceased
- 2008-09-10 DK DK08801987.2T patent/DK2200600T3/da active
- 2008-09-10 EP EP12006826.7A patent/EP2548552B1/en active Active
- 2008-09-10 AR ARP080103937A patent/AR070026A1/es not_active Application Discontinuation
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2010
- 2010-02-22 ZA ZA2010/01262A patent/ZA201001262B/en unknown
- 2010-02-22 ZA ZA2010/01261A patent/ZA201001261B/en unknown
- 2010-02-22 ZA ZA2010/01264A patent/ZA201001264B/en unknown
- 2010-02-22 ZA ZA2010/01263A patent/ZA201001263B/en unknown
-
2011
- 2011-09-08 RU RU2011137131/15A patent/RU2011137131A/ru not_active Application Discontinuation
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2012
- 2012-01-16 HR HR20120046T patent/HRP20120046T1/hr unknown
-
2014
- 2014-06-12 JP JP2014121268A patent/JP5784188B2/ja not_active Expired - Fee Related
- 2014-06-12 JP JP2014121269A patent/JP5784189B2/ja not_active Expired - Fee Related
- 2014-09-30 US US14/501,438 patent/US20150018425A1/en not_active Abandoned
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2016
- 2016-10-12 US US15/291,527 patent/US20170027885A1/en not_active Abandoned
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