HK1247828A1 - 多功能兩性離子聚合物共軛物 - Google Patents

多功能兩性離子聚合物共軛物

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Publication number
HK1247828A1
HK1247828A1 HK18107293.9A HK18107293A HK1247828A1 HK 1247828 A1 HK1247828 A1 HK 1247828A1 HK 18107293 A HK18107293 A HK 18107293A HK 1247828 A1 HK1247828 A1 HK 1247828A1
Authority
HK
Hong Kong
Prior art keywords
polymer conjugates
zwitterionic polymer
multifunctional
multifunctional zwitterionic
conjugates
Prior art date
Application number
HK18107293.9A
Other languages
English (en)
Inventor
斯蒂芬‧A‧查爾斯
維克托‧D‧皮爾羅斯
萊恩‧A‧克利茲比
迪迪埃‧G‧貝努瓦
韋恩‧杜
Original Assignee
科迪亞克科技公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 科迪亞克科技公司 filed Critical 科迪亞克科技公司
Publication of HK1247828A1 publication Critical patent/HK1247828A1/zh

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    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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    • C08F220/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
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    • C08F2438/01Atom Transfer Radical Polymerization [ATRP] or reverse ATRP
HK18107293.9A 2009-12-18 2018-06-04 多功能兩性離子聚合物共軛物 HK1247828A1 (zh)

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EP (3) EP2512462B1 (zh)
JP (5) JP5760007B2 (zh)
KR (1) KR101852044B1 (zh)
CN (2) CN102811713B (zh)
AU (1) AU2010330727B2 (zh)
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CA (2) CA2783615C (zh)
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CO (1) CO6592052A2 (zh)
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HK (1) HK1247828A1 (zh)
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PT (2) PT2512462T (zh)
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US20100166700A1 (en) 2006-02-28 2010-07-01 Oligasis Corporation Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates and Their Preparation
CA2665493A1 (en) 2006-08-07 2008-02-14 University Of Washington Mixed charge copolymers and hydrogels
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