HK1217482A1 - Enzyme modulators and therapies - Google Patents

Enzyme modulators and therapies Download PDF

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Publication number
HK1217482A1
HK1217482A1 HK16105411.2A HK16105411A HK1217482A1 HK 1217482 A1 HK1217482 A1 HK 1217482A1 HK 16105411 A HK16105411 A HK 16105411A HK 1217482 A1 HK1217482 A1 HK 1217482A1
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HK
Hong Kong
Prior art keywords
c6alkyl
group
phenyl
butyl
pyrazol
Prior art date
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HK16105411.2A
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English (en)
Chinese (zh)
Inventor
L. Flynn Daniel
A. Petillo Peter
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Deciphera Pharmaceuticals, Llc
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Publication of HK1217482A1 publication Critical patent/HK1217482A1/en

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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D471/04—Ortho-condensed systems

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK16105411.2A 2004-12-23 2016-05-11 Enzyme modulators and therapies HK1217482A1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US63908704P 2004-12-23 2004-12-23
US63896804P 2004-12-23 2004-12-23
US63898704P 2004-12-23 2004-12-23
US63898604P 2004-12-23 2004-12-23
US20040638987P 2004-12-23
US20040638986P 2004-12-23
US20040639087P 2004-12-23
US20040638968P 2004-12-23

Publications (1)

Publication Number Publication Date
HK1217482A1 true HK1217482A1 (en) 2017-01-13

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HK16105411.2A HK1217482A1 (en) 2004-12-23 2016-05-11 Enzyme modulators and therapies

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US (2) US20070078121A1 (https=)
EP (2) EP2942349A1 (https=)
JP (1) JP5197016B2 (https=)
AU (1) AU2005321946B2 (https=)
CA (1) CA2592118C (https=)
HK (1) HK1217482A1 (https=)
WO (1) WO2006071940A2 (https=)

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WO2006071940A2 (en) 2004-12-23 2006-07-06 Deciphera Pharmaceuticals, Llc Enzyme modulators and treatments
EP1833819A1 (en) 2004-12-30 2007-09-19 Astex Therapeutics Limited Pyrazole compounds that modulate the activity of cdk, gsk and aurora kinases
DE102005015253A1 (de) * 2005-04-04 2006-10-05 Merck Patent Gmbh Pyrazolderivate
PE20110285A1 (es) 2005-10-19 2011-06-04 Gruenenthal Chemie Derivados de sulfonamidofenil propionamida como ligandos del receptor vaniloide del subtipo 1
WO2007047919A2 (en) 2005-10-20 2007-04-26 University Of South Florida Treatment of restenosis and stenosis with dasatinib
US8580798B2 (en) * 2005-12-21 2013-11-12 Bayer Intellectual Property Gmbh Substituted pyrimidine derivatives useful in the treatment of cancer and other disorders
EP1968579A1 (en) 2005-12-30 2008-09-17 Astex Therapeutics Limited Pharmaceutical compounds
EP2049119A2 (en) 2006-06-29 2009-04-22 Astex Therapeutics Limited Pharmaceutical combinations of 1-cyclopropyl-3-[3-(5-morphoolin-4-ylmethyl-1h-benzoimidazol-2-yl)-1h-1-pyrazol-4-yl]-urea
US8188113B2 (en) * 2006-09-14 2012-05-29 Deciphera Pharmaceuticals, Inc. Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
US7897762B2 (en) * 2006-09-14 2011-03-01 Deciphera Pharmaceuticals, Llc Kinase inhibitors useful for the treatment of proliferative diseases
US7790756B2 (en) * 2006-10-11 2010-09-07 Deciphera Pharmaceuticals, Llc Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
EA200900573A1 (ru) * 2006-10-20 2009-10-30 АйАрЭм ЭлЭлСи Композиции и способы для модуляции рецепторов c-kit и pdgfr
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AU2005321946B2 (en) 2012-08-16
EP1835934A2 (en) 2007-09-26
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WO2006071940A3 (en) 2009-04-23
AU2005321946A1 (en) 2006-07-06
US8163756B2 (en) 2012-04-24
CA2592118A1 (en) 2006-07-06
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EP1835934A4 (en) 2010-07-28
US20080113967A1 (en) 2008-05-15

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