AU2005321946B2 - Enzyme modulators and treatments - Google Patents

Enzyme modulators and treatments Download PDF

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Publication number
AU2005321946B2
AU2005321946B2 AU2005321946A AU2005321946A AU2005321946B2 AU 2005321946 B2 AU2005321946 B2 AU 2005321946B2 AU 2005321946 A AU2005321946 A AU 2005321946A AU 2005321946 A AU2005321946 A AU 2005321946A AU 2005321946 B2 AU2005321946 B2 AU 2005321946B2
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AU2005321946A1 (en
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Daniel L. Flynn
Peter A. Petillo
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Deciphera Pharmaceuticals LLC
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Deciphera Pharmaceuticals LLC
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    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2005321946A 2004-12-23 2005-12-23 Enzyme modulators and treatments Ceased AU2005321946B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US63908704P 2004-12-23 2004-12-23
US63898604P 2004-12-23 2004-12-23
US63898704P 2004-12-23 2004-12-23
US63896804P 2004-12-23 2004-12-23
US60/638,987 2004-12-23
US60/638,968 2004-12-23
US60/639,087 2004-12-23
US60/638,986 2004-12-23
PCT/US2005/047270 WO2006071940A2 (en) 2004-12-23 2005-12-23 Enzyme modulators and treatments

Publications (2)

Publication Number Publication Date
AU2005321946A1 AU2005321946A1 (en) 2006-07-06
AU2005321946B2 true AU2005321946B2 (en) 2012-08-16

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AU2005321946A Ceased AU2005321946B2 (en) 2004-12-23 2005-12-23 Enzyme modulators and treatments

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US (2) US20070078121A1 (https=)
EP (2) EP2942349A1 (https=)
JP (1) JP5197016B2 (https=)
AU (1) AU2005321946B2 (https=)
CA (1) CA2592118C (https=)
HK (1) HK1217482A1 (https=)
WO (1) WO2006071940A2 (https=)

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US7144911B2 (en) 2002-12-31 2006-12-05 Deciphera Pharmaceuticals Llc Anti-inflammatory medicaments
US20110275630A1 (en) * 2003-06-02 2011-11-10 Abbott Laboratories Isoindolinone kinase inhibitors
CA2592118C (en) 2004-12-23 2015-11-17 Deciphera Pharmaceuticals, Llc Urea derivatives as enzyme modulators
MX2007008008A (es) 2004-12-30 2007-11-12 Astex Therapeutics Ltd Compuestos de pirazol que modulan la actividad de las cinasas cdk, gsk y aurora.
DE102005015253A1 (de) * 2005-04-04 2006-10-05 Merck Patent Gmbh Pyrazolderivate
DK1940821T3 (da) 2005-10-19 2013-06-10 Gruenenthal Gmbh Nye vanilloid-receptorligander og deres anvendelse til fremstilling af lægemidler.
WO2007047919A2 (en) * 2005-10-20 2007-04-26 University Of South Florida Treatment of restenosis and stenosis with dasatinib
WO2007075650A2 (en) * 2005-12-21 2007-07-05 Bayer Healthcare Ag Substituted pyrimidine derivatives useful in the treatment of cancer and other disorders
US8399442B2 (en) 2005-12-30 2013-03-19 Astex Therapeutics Limited Pharmaceutical compounds
JP5523829B2 (ja) 2006-06-29 2014-06-18 アステックス、セラピューティックス、リミテッド 複合薬剤
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HK1217482A1 (en) 2017-01-13
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