DK1940821T3 - Nye vanilloid-receptorligander og deres anvendelse til fremstilling af lægemidler. - Google Patents
Nye vanilloid-receptorligander og deres anvendelse til fremstilling af lægemidler.Info
- Publication number
- DK1940821T3 DK1940821T3 DK06806372.6T DK06806372T DK1940821T3 DK 1940821 T3 DK1940821 T3 DK 1940821T3 DK 06806372 T DK06806372 T DK 06806372T DK 1940821 T3 DK1940821 T3 DK 1940821T3
- Authority
- DK
- Denmark
- Prior art keywords
- drugs
- manufacture
- receptor ligands
- vanilloid receptor
- novel vanilloid
- Prior art date
Links
- 102000011040 TRPV Cation Channels Human genes 0.000 title 1
- 108010062740 TRPV Cation Channels Proteins 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
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- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
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- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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DE102005055486 | 2005-11-18 | ||
PCT/EP2006/010057 WO2007045462A2 (de) | 2005-10-19 | 2006-10-19 | Neue vanilloid-rezeptor liganden und ihre verwendung zur herstellung von arzneimitteln |
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PT (1) | PT1940821E (da) |
SI (1) | SI1940821T1 (da) |
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CN1209016C (zh) | 1999-08-18 | 2005-07-06 | 阿方蒂农科有限公司 | 杀真菌剂 |
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BRPI0618417A2 (pt) | 2005-10-19 | 2012-07-31 | Gruenenthal Chemie | novos ligandos de receptores de vanilàide e seu uso para produzir medicamentos |
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- 2006-10-19 PE PE2006001265A patent/PE20070528A1/es not_active Application Discontinuation
- 2006-10-19 JP JP2008535966A patent/JP5323485B2/ja not_active Expired - Fee Related
- 2006-10-19 CN CN2013101402854A patent/CN103382176A/zh active Pending
- 2006-10-19 NZ NZ567936A patent/NZ567936A/en not_active IP Right Cessation
- 2006-10-19 EP EP11006751A patent/EP2388258A1/de not_active Withdrawn
- 2006-10-19 EP EP06806372A patent/EP1940821B1/de active Active
- 2006-10-19 AR ARP060104575A patent/AR056875A1/es unknown
- 2006-10-19 CN CN200680047690XA patent/CN101331124B/zh not_active Expired - Fee Related
- 2006-10-19 KR KR1020087011879A patent/KR101347102B1/ko not_active IP Right Cessation
- 2006-10-19 AU AU2006303437A patent/AU2006303437B2/en not_active Ceased
- 2006-10-19 PE PE2011000141A patent/PE20110285A1/es not_active Application Discontinuation
- 2006-10-19 DK DK06806372.6T patent/DK1940821T3/da active
-
2008
- 2008-04-07 IL IL190654A patent/IL190654A/en not_active IP Right Cessation
- 2008-05-08 NO NO20082160A patent/NO20082160L/no not_active Application Discontinuation
-
2012
- 2012-04-24 IL IL219380A patent/IL219380A/en not_active IP Right Cessation
- 2012-05-29 AU AU2012203162A patent/AU2012203162A1/en not_active Abandoned
-
2013
- 2013-05-24 HR HRP20130454TT patent/HRP20130454T1/hr unknown
-
2014
- 2014-02-25 US US14/190,007 patent/US20140179686A1/en not_active Abandoned
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