DK1786759T3 - Nye derivater af 3,5-seco-4-nor-cholestan og deres anvendelser - Google Patents

Nye derivater af 3,5-seco-4-nor-cholestan og deres anvendelser

Info

Publication number
DK1786759T3
DK1786759T3 DK05798253.0T DK05798253T DK1786759T3 DK 1786759 T3 DK1786759 T3 DK 1786759T3 DK 05798253 T DK05798253 T DK 05798253T DK 1786759 T3 DK1786759 T3 DK 1786759T3
Authority
DK
Denmark
Prior art keywords
cholestane
seco
applications
new derivatives
derivatives
Prior art date
Application number
DK05798253.0T
Other languages
English (en)
Inventor
Thierry Bordet
Cyrille Drouot
Original Assignee
Trophos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trophos filed Critical Trophos
Application granted granted Critical
Publication of DK1786759T3 publication Critical patent/DK1786759T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK05798253.0T 2004-09-07 2005-08-19 Nye derivater af 3,5-seco-4-nor-cholestan og deres anvendelser DK1786759T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0409436A FR2874923B1 (fr) 2004-09-07 2004-09-07 Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
PCT/FR2005/002116 WO2006027454A1 (fr) 2004-09-07 2005-08-19 Nouveaux derives du 3,5-seco-4-nor-cholestane et leurs utilisations

Publications (1)

Publication Number Publication Date
DK1786759T3 true DK1786759T3 (da) 2012-10-15

Family

ID=34949389

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05798253.0T DK1786759T3 (da) 2004-09-07 2005-08-19 Nye derivater af 3,5-seco-4-nor-cholestan og deres anvendelser

Country Status (16)

Country Link
US (1) US9045393B2 (da)
EP (1) EP1786759B1 (da)
JP (1) JP5350630B2 (da)
KR (1) KR101190464B1 (da)
CN (1) CN101018762B (da)
AU (1) AU2005281640B2 (da)
BR (1) BRPI0514792A (da)
CA (1) CA2576393C (da)
DK (1) DK1786759T3 (da)
ES (1) ES2390462T3 (da)
FR (1) FR2874923B1 (da)
IL (1) IL181216A (da)
MX (1) MX2007002531A (da)
PL (1) PL1786759T3 (da)
RU (1) RU2398764C2 (da)
WO (1) WO2006027454A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2874923B1 (fr) 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
FR2919180B1 (fr) * 2007-07-25 2009-11-27 Trophos Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
FR2940650B1 (fr) * 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation
WO2012069150A2 (en) 2010-11-22 2012-05-31 Powerpore Gmbh Cytoprotectant agents for the prevention of drug-associated side-effects
FR2979239A1 (fr) * 2011-08-25 2013-03-01 Trophos Liposome comprenant au moins un derive de cholesterol

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2883424A (en) * 1956-06-20 1959-04-21 Monsanto Chemicals Dihydroxy steroid derivatives and method of preparing same
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
GB0117326D0 (en) * 2001-07-16 2001-09-05 Univ Aberdeen Napthoquinone-type inhibitors of protein aggregation
PT1601363E (pt) * 2003-03-11 2012-08-17 Trophos Aplicação como medicamentos de derivados da colest-4-en-3- ona, composições farmacêuticas que os contêm e novos derivados
FR2874923B1 (fr) 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
FR2894968B1 (fr) * 2005-12-20 2008-02-22 Trophos Sa Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2899108B1 (fr) * 2006-03-31 2012-02-03 Trophos Utilisation de derives du cholest-4-en-3-one pour l'obtention d'un medicament cytoprotecteur
FR2914188B1 (fr) * 2007-03-28 2012-06-22 Trophos Nouvelle composition a base d'oxime de cholest-4-en-3-one
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
FR2919180B1 (fr) * 2007-07-25 2009-11-27 Trophos Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
JP2011502112A (ja) * 2007-10-30 2011-01-20 トロフォ 抗ガン治療の副作用を治療するための新規組成物
FR2934596B1 (fr) * 2008-07-30 2015-04-10 Trophos Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2940650B1 (fr) * 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation

Also Published As

Publication number Publication date
US9045393B2 (en) 2015-06-02
EP1786759B1 (fr) 2012-07-04
IL181216A0 (en) 2007-07-04
CA2576393C (fr) 2013-06-11
ES2390462T3 (es) 2012-11-13
CN101018762B (zh) 2011-12-21
CN101018762A (zh) 2007-08-15
RU2007112950A (ru) 2008-10-20
WO2006027454A1 (fr) 2006-03-16
KR101190464B1 (ko) 2012-10-12
FR2874923B1 (fr) 2006-10-27
EP1786759A1 (fr) 2007-05-23
AU2005281640A1 (en) 2006-03-16
MX2007002531A (es) 2007-05-23
BRPI0514792A (pt) 2008-06-24
PL1786759T3 (pl) 2012-11-30
JP5350630B2 (ja) 2013-11-27
IL181216A (en) 2013-07-31
US20080275130A1 (en) 2008-11-06
JP2008512368A (ja) 2008-04-24
RU2398764C2 (ru) 2010-09-10
FR2874923A1 (fr) 2006-03-10
CA2576393A1 (fr) 2006-03-16
AU2005281640B2 (en) 2011-02-03
KR20070101218A (ko) 2007-10-16

Similar Documents

Publication Publication Date Title
NO20054083D0 (no) Nye sammenkoblede triazoloner og deres anvendelse
DK2057153T3 (da) (3-aryl-piperazin-1-yl)-derivater af 6,7 dialkoxyquinazolin, 6,7- dialkoxyphtalazin og 6,7-dialkoxyisoquinolin
DK1651644T3 (da) Substituerede derivater af thiazol-benzoisothiazoldioxid, fremgangsmåde deraf og deres anvendelse
DK1928886T3 (da) Pyridin-derivater og deres anvendelse i behandlingen af psykotiske lidelser
DK1802579T3 (da) Derivater af 3-arylaminopyridin
NO20054224D0 (no) Nye 2-pyridinkarboksamidderivater
DK1937824T3 (da) Sammensætninger af tRNA og anvendelser deraf
DK1789401T3 (da) Isoxazolinderivater og deres anvendelse som herbicider
DK2332909T3 (da) Hydroxybenzamidderivater og deres anvendelse som inhibitorer af hsp90
DK1954140T3 (da) Glycerollevulinatketaler og deres anvendelse
DK1751087T3 (da) Levodopa-derivater og sammensætninger og anvendelser deraf
DK1480955T3 (da) O-cyclopropyl-carboxanilider og deres anvendelse som fungicider
NO20055219D0 (no) Nye forbindelser
DK1891571T3 (da) Hæmning af spredning af uønskede koder og data
NO20044432L (no) Nye forbindelser
NO20053569L (no) Substituerte 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazinderivater og deres anvendelse som nevrokininantagonister
DK1636228T3 (da) Nye pyridopyraziner og deres anvendelse som kinasemodulatorer
DK2046715T3 (da) Substituerede 1,3-diphenylpropanderivater, præparater og anvendelser deraf
DK1888595T3 (da) Spiro-oxindolforbindelser og deres anvendelser som terapeutiske midler
IS7344A (is) Stýrð efnasmíði síprasídóns og samsetninga af því
NO20054135D0 (no) Kipolinon/benzoksazin derivater og anvendelser derav
DK2094842T3 (da) Nye laccaser, sammensætninger og anvendelsesfremgangsmåder
IS8178A (is) Oxazólidinon fúkalyf setin með sýklóprópýlhóp og afleiður þeirra
ATE405573T1 (de) Amid-prodrug von gemcitabin, zusammensetzungen und verwendung damit
DK1786759T3 (da) Nye derivater af 3,5-seco-4-nor-cholestan og deres anvendelser