PL1786759T3 - Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie - Google Patents

Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie

Info

Publication number
PL1786759T3
PL1786759T3 PL05798253T PL05798253T PL1786759T3 PL 1786759 T3 PL1786759 T3 PL 1786759T3 PL 05798253 T PL05798253 T PL 05798253T PL 05798253 T PL05798253 T PL 05798253T PL 1786759 T3 PL1786759 T3 PL 1786759T3
Authority
PL
Poland
Prior art keywords
norcholestane
seco
novel derivatives
derivatives
novel
Prior art date
Application number
PL05798253T
Other languages
English (en)
Inventor
Thierry Bordet
Cyrille Drouot
Original Assignee
Trophos
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trophos filed Critical Trophos
Publication of PL1786759T3 publication Critical patent/PL1786759T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/34Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/487Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
PL05798253T 2004-09-07 2005-08-19 Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie PL1786759T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0409436A FR2874923B1 (fr) 2004-09-07 2004-09-07 Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
PCT/FR2005/002116 WO2006027454A1 (fr) 2004-09-07 2005-08-19 Nouveaux derives du 3,5-seco-4-nor-cholestane et leurs utilisations
EP05798253A EP1786759B1 (fr) 2004-09-07 2005-08-19 Nouveaux derives du 3,5-seco-4-nor-cholestane et leurs utilisations

Publications (1)

Publication Number Publication Date
PL1786759T3 true PL1786759T3 (pl) 2012-11-30

Family

ID=34949389

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05798253T PL1786759T3 (pl) 2004-09-07 2005-08-19 Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie

Country Status (16)

Country Link
US (1) US9045393B2 (pl)
EP (1) EP1786759B1 (pl)
JP (1) JP5350630B2 (pl)
KR (1) KR101190464B1 (pl)
CN (1) CN101018762B (pl)
AU (1) AU2005281640B2 (pl)
BR (1) BRPI0514792A (pl)
CA (1) CA2576393C (pl)
DK (1) DK1786759T3 (pl)
ES (1) ES2390462T3 (pl)
FR (1) FR2874923B1 (pl)
IL (1) IL181216A (pl)
MX (1) MX2007002531A (pl)
PL (1) PL1786759T3 (pl)
RU (1) RU2398764C2 (pl)
WO (1) WO2006027454A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2874923B1 (fr) 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
FR2898272B1 (fr) * 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2919182B1 (fr) * 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
FR2919180B1 (fr) * 2007-07-25 2009-11-27 Trophos Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
FR2940650B1 (fr) * 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation
WO2012069150A2 (en) 2010-11-22 2012-05-31 Powerpore Gmbh Cytoprotectant agents for the prevention of drug-associated side-effects
FR2979239A1 (fr) * 2011-08-25 2013-03-01 Trophos Liposome comprenant au moins un derive de cholesterol

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2883424A (en) * 1956-06-20 1959-04-21 Monsanto Chemicals Dihydroxy steroid derivatives and method of preparing same
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
GB0117326D0 (en) * 2001-07-16 2001-09-05 Univ Aberdeen Napthoquinone-type inhibitors of protein aggregation
PT1601363E (pt) 2003-03-11 2012-08-17 Trophos Aplicação como medicamentos de derivados da colest-4-en-3- ona, composições farmacêuticas que os contêm e novos derivados
FR2874923B1 (fr) 2004-09-07 2006-10-27 Trophos Sa Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
FR2894968B1 (fr) 2005-12-20 2008-02-22 Trophos Sa Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2898272B1 (fr) 2006-03-09 2008-07-04 Trophos Sa Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur
FR2899108B1 (fr) 2006-03-31 2012-02-03 Trophos Utilisation de derives du cholest-4-en-3-one pour l'obtention d'un medicament cytoprotecteur
FR2914188B1 (fr) 2007-03-28 2012-06-22 Trophos Nouvelle composition a base d'oxime de cholest-4-en-3-one
FR2919180B1 (fr) 2007-07-25 2009-11-27 Trophos Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants
FR2919182B1 (fr) 2007-07-25 2009-11-13 Trophos Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants
MX2010004859A (es) 2007-10-30 2010-06-21 Trophos Nueva composicion para tratar los efectos secundarios del tratamiento anticanceroso.
FR2934596B1 (fr) 2008-07-30 2015-04-10 Trophos Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
FR2940650B1 (fr) 2008-12-29 2017-01-27 Trophos Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation

Also Published As

Publication number Publication date
WO2006027454A1 (fr) 2006-03-16
RU2007112950A (ru) 2008-10-20
KR101190464B1 (ko) 2012-10-12
CN101018762B (zh) 2011-12-21
ES2390462T3 (es) 2012-11-13
JP2008512368A (ja) 2008-04-24
IL181216A0 (en) 2007-07-04
US20080275130A1 (en) 2008-11-06
AU2005281640B2 (en) 2011-02-03
IL181216A (en) 2013-07-31
CA2576393C (fr) 2013-06-11
JP5350630B2 (ja) 2013-11-27
US9045393B2 (en) 2015-06-02
EP1786759A1 (fr) 2007-05-23
FR2874923A1 (fr) 2006-03-10
KR20070101218A (ko) 2007-10-16
DK1786759T3 (da) 2012-10-15
MX2007002531A (es) 2007-05-23
CA2576393A1 (fr) 2006-03-16
RU2398764C2 (ru) 2010-09-10
CN101018762A (zh) 2007-08-15
FR2874923B1 (fr) 2006-10-27
AU2005281640A1 (en) 2006-03-16
BRPI0514792A (pt) 2008-06-24
EP1786759B1 (fr) 2012-07-04

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