HK1147271A1 - Rationally designed, synthetic antibody libraries and uses therefor - Google Patents
Rationally designed, synthetic antibody libraries and uses thereforInfo
- Publication number
- HK1147271A1 HK1147271A1 HK11101445.6A HK11101445A HK1147271A1 HK 1147271 A1 HK1147271 A1 HK 1147271A1 HK 11101445 A HK11101445 A HK 11101445A HK 1147271 A1 HK1147271 A1 HK 1147271A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- antibody libraries
- synthetic antibody
- rationally designed
- uses therefor
- therefor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99378507P | 2007-09-14 | 2007-09-14 | |
| PCT/US2008/076300 WO2009036379A2 (en) | 2007-09-14 | 2008-09-12 | Rationally designed, synthetic antibody libraries and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1147271A1 true HK1147271A1 (en) | 2011-08-05 |
Family
ID=40350153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK11101445.6A HK1147271A1 (en) | 2007-09-14 | 2011-02-15 | Rationally designed, synthetic antibody libraries and uses therefor |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US8691730B2 (de) |
| EP (3) | EP2193146B1 (de) |
| JP (6) | JP5933894B2 (de) |
| CN (1) | CN101855242B (de) |
| AU (1) | AU2008298603B2 (de) |
| BR (1) | BRPI0816785A2 (de) |
| CA (3) | CA3187687A1 (de) |
| DK (1) | DK3124497T3 (de) |
| HK (1) | HK1147271A1 (de) |
| MX (3) | MX2010002661A (de) |
| WO (1) | WO2009036379A2 (de) |
Families Citing this family (203)
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| US8877688B2 (en) | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
| US8067339B2 (en) | 2008-07-09 | 2011-11-29 | Merck Sharp & Dohme Corp. | Surface display of whole antibodies in eukaryotes |
| WO2010059315A1 (en) | 2008-11-18 | 2010-05-27 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
| JP2013504602A (ja) * | 2009-09-14 | 2013-02-07 | ダイアックス コーポレーション | 新しく設計したｈｃｃｄｒ３を含む遺伝子パッケージライブラリー |
| WO2011035205A2 (en) | 2009-09-18 | 2011-03-24 | Calmune Corporation | Antibodies against candida, collections thereof and methods of use |
| US9051375B2 (en) | 2010-12-21 | 2015-06-09 | The University Of Western Ontario | Alkali-resistant variants of protein A and their use in affinity chromatography |
| WO2012094653A2 (en) | 2011-01-07 | 2012-07-12 | Massachusetts Institute Of Technology | Compositions and methods for macromolecular drug delivery |
| SG186552A1 (en) | 2011-06-08 | 2013-01-30 | Emd Millipore Corp | Chromatography matrices including novel staphylococcus aureus protein a based ligands |
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2008
- 2008-09-12 CA CA3187687A patent/CA3187687A1/en active Pending
- 2008-09-12 EP EP08830652.7A patent/EP2193146B1/de active Active
- 2008-09-12 MX MX2010002661A patent/MX2010002661A/es active IP Right Grant
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- 2008-09-12 EP EP20161796.6A patent/EP3753947A1/de active Pending
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- 2008-09-12 BR BRPI0816785A patent/BRPI0816785A2/pt not_active Application Discontinuation
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- 2008-09-12 WO PCT/US2008/076300 patent/WO2009036379A2/en active Application Filing
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