HK1147271A1 - Rationally designed, synthetic antibody libraries and uses therefor - Google Patents

Rationally designed, synthetic antibody libraries and uses therefor

Info

Publication number
HK1147271A1
HK1147271A1 HK11101445.6A HK11101445A HK1147271A1 HK 1147271 A1 HK1147271 A1 HK 1147271A1 HK 11101445 A HK11101445 A HK 11101445A HK 1147271 A1 HK1147271 A1 HK 1147271A1
Authority
HK
Hong Kong
Prior art keywords
antibody libraries
synthetic antibody
rationally designed
uses therefor
therefor
Prior art date
Application number
HK11101445.6A
Other languages
English (en)
Chinese (zh)
Inventor
‧瓦斯克斯
‧費爾德豪斯
‧格恩格羅斯
‧維特拉普
Original Assignee
阿迪馬布有限責任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 阿迪馬布有限責任公司 filed Critical 阿迪馬布有限責任公司
Publication of HK1147271A1 publication Critical patent/HK1147271A1/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/10Libraries containing peptides or polypeptides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/06Biochemical methods, e.g. using enzymes or whole viable microorganisms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK11101445.6A 2007-09-14 2011-02-15 Rationally designed, synthetic antibody libraries and uses therefor HK1147271A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99378507P 2007-09-14 2007-09-14
PCT/US2008/076300 WO2009036379A2 (en) 2007-09-14 2008-09-12 Rationally designed, synthetic antibody libraries and uses therefor

Publications (1)

Publication Number Publication Date
HK1147271A1 true HK1147271A1 (en) 2011-08-05

Family

ID=40350153

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11101445.6A HK1147271A1 (en) 2007-09-14 2011-02-15 Rationally designed, synthetic antibody libraries and uses therefor

Country Status (11)

Country Link
US (4) US8691730B2 (de)
EP (3) EP3753947A1 (de)
JP (6) JP5933894B2 (de)
CN (1) CN101855242B (de)
AU (1) AU2008298603B2 (de)
BR (1) BRPI0816785A2 (de)
CA (3) CA3187687A1 (de)
DK (1) DK3124497T3 (de)
HK (1) HK1147271A1 (de)
MX (3) MX344415B (de)
WO (1) WO2009036379A2 (de)

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