ES2536465T3 - Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres - Google Patents

Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres Download PDF

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Publication number
ES2536465T3
ES2536465T3 ES08017305.7T ES08017305T ES2536465T3 ES 2536465 T3 ES2536465 T3 ES 2536465T3 ES 08017305 T ES08017305 T ES 08017305T ES 2536465 T3 ES2536465 T3 ES 2536465T3
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Prior art keywords
cancer
peptide
tumor
peptides
expression
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ES08017305.7T
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English (en)
Spanish (es)
Inventor
Oliver Schoor
Norbert Hilf
Toni Weinschenk
Claudia Trautwein
Steffen Walter
Harpreet Singh
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Immatics Biotechnologies GmbH
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Immatics Biotechnologies GmbH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/34Antigenic peptides
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • C12N5/0638Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis
    • G01N33/5759
    • AHUMAN NECESSITIES
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    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
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    • A61K2039/55516Proteins; Peptides
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    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • A61K2039/6093Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
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    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
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    • C07KPEPTIDES
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Immunology (AREA)
  • Public Health (AREA)
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  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
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ES08017305.7T 2008-10-01 2008-10-01 Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres Active ES2536465T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20080017305 EP2172211B1 (en) 2008-10-01 2008-10-01 Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers

Publications (1)

Publication Number Publication Date
ES2536465T3 true ES2536465T3 (es) 2015-05-25

Family

ID=40342382

Family Applications (12)

Application Number Title Priority Date Filing Date
ES08017305.7T Active ES2536465T3 (es) 2008-10-01 2008-10-01 Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres
ES08017921.1T Active ES2607460T3 (es) 2008-10-01 2008-10-13 Nueva inmunoterapia contra varios tumores incluidos tumores neuronales y cerebrales
ES16179192T Active ES2819244T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16165070T Active ES2710608T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179174T Active ES2804723T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179163T Active ES2802226T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179226T Active ES2802227T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179214T Active ES2788129T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES09778750.1T Active ES2584245T3 (es) 2008-10-01 2009-09-28 Composición que comprende péptidos asociados a tumores y una vacuna para el tratamiento del glioblastoma y de otros tipos de cáncer
ES16179169T Active ES2770090T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179241T Active ES2708654T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra varios tumores incluyendo tumores cerebrales y neuronales
ES09778749.3T Active ES2612466T3 (es) 2008-10-01 2009-09-28 Composición de péptidos asociados a tumores y vacuna contra el cáncer relacionada con ellos para el tratamiento del glioblastoma (GBM) y de otros tipos de cáncer

Family Applications After (11)

Application Number Title Priority Date Filing Date
ES08017921.1T Active ES2607460T3 (es) 2008-10-01 2008-10-13 Nueva inmunoterapia contra varios tumores incluidos tumores neuronales y cerebrales
ES16179192T Active ES2819244T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16165070T Active ES2710608T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179174T Active ES2804723T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179163T Active ES2802226T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179226T Active ES2802227T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179214T Active ES2788129T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES09778750.1T Active ES2584245T3 (es) 2008-10-01 2009-09-28 Composición que comprende péptidos asociados a tumores y una vacuna para el tratamiento del glioblastoma y de otros tipos de cáncer
ES16179169T Active ES2770090T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179241T Active ES2708654T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra varios tumores incluyendo tumores cerebrales y neuronales
ES09778749.3T Active ES2612466T3 (es) 2008-10-01 2009-09-28 Composición de péptidos asociados a tumores y vacuna contra el cáncer relacionada con ellos para el tratamiento del glioblastoma (GBM) y de otros tipos de cáncer

Country Status (24)

Country Link
US (19) US8318677B2 (enExample)
EP (12) EP2172211B1 (enExample)
JP (10) JP5855940B2 (enExample)
KR (6) KR102133402B1 (enExample)
CN (3) CN102170901B (enExample)
AU (2) AU2009300087B2 (enExample)
BR (2) BRPI0920759A2 (enExample)
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