ES2788129T8 - Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales - Google Patents
Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronalesInfo
- Publication number
- ES2788129T8 ES2788129T8 ES16179214T ES16179214T ES2788129T8 ES 2788129 T8 ES2788129 T8 ES 2788129T8 ES 16179214 T ES16179214 T ES 16179214T ES 16179214 T ES16179214 T ES 16179214T ES 2788129 T8 ES2788129 T8 ES 2788129T8
- Authority
- ES
- Spain
- Prior art keywords
- tumors
- against various
- including brain
- neuronal
- immunotherapy against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000003174 Brain Neoplasms Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 210000004556 brain Anatomy 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
- 208000014500 neuronal tumor Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4634—Antigenic peptides; polypeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/605—MHC molecules or ligands thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20080017305 EP2172211B1 (en) | 2008-10-01 | 2008-10-01 | Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers |
EP08017921.1A EP2172212B1 (en) | 2008-10-01 | 2008-10-13 | Novel immunotherapy against several tumors including neuronal and brain tumors |
US10592808P | 2008-10-16 | 2008-10-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2788129T3 ES2788129T3 (es) | 2020-10-20 |
ES2788129T8 true ES2788129T8 (es) | 2020-11-04 |
Family
ID=40342382
Family Applications (12)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES08017305.7T Active ES2536465T3 (es) | 2008-10-01 | 2008-10-01 | Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres |
ES08017921.1T Active ES2607460T3 (es) | 2008-10-01 | 2008-10-13 | Nueva inmunoterapia contra varios tumores incluidos tumores neuronales y cerebrales |
ES16179174T Active ES2804723T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES09778750.1T Active ES2584245T3 (es) | 2008-10-01 | 2009-09-28 | Composición que comprende péptidos asociados a tumores y una vacuna para el tratamiento del glioblastoma y de otros tipos de cáncer |
ES16179169T Active ES2770090T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16179192T Active ES2819244T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16179226T Active ES2802227T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16165070T Active ES2710608T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16179241T Active ES2708654T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra varios tumores incluyendo tumores cerebrales y neuronales |
ES09778749.3T Active ES2612466T3 (es) | 2008-10-01 | 2009-09-28 | Composición de péptidos asociados a tumores y vacuna contra el cáncer relacionada con ellos para el tratamiento del glioblastoma (GBM) y de otros tipos de cáncer |
ES16179214T Active ES2788129T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16179163T Active ES2802226T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
Family Applications Before (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES08017305.7T Active ES2536465T3 (es) | 2008-10-01 | 2008-10-01 | Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres |
ES08017921.1T Active ES2607460T3 (es) | 2008-10-01 | 2008-10-13 | Nueva inmunoterapia contra varios tumores incluidos tumores neuronales y cerebrales |
ES16179174T Active ES2804723T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES09778750.1T Active ES2584245T3 (es) | 2008-10-01 | 2009-09-28 | Composición que comprende péptidos asociados a tumores y una vacuna para el tratamiento del glioblastoma y de otros tipos de cáncer |
ES16179169T Active ES2770090T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16179192T Active ES2819244T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16179226T Active ES2802227T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16165070T Active ES2710608T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
ES16179241T Active ES2708654T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra varios tumores incluyendo tumores cerebrales y neuronales |
ES09778749.3T Active ES2612466T3 (es) | 2008-10-01 | 2009-09-28 | Composición de péptidos asociados a tumores y vacuna contra el cáncer relacionada con ellos para el tratamiento del glioblastoma (GBM) y de otros tipos de cáncer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES16179163T Active ES2802226T3 (es) | 2008-10-01 | 2009-09-28 | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales |
Country Status (25)
Country | Link |
---|---|
US (19) | US8119139B2 (es) |
EP (12) | EP2172211B1 (es) |
JP (10) | JP5855940B2 (es) |
KR (6) | KR102392070B1 (es) |
CN (3) | CN106986919A (es) |
AU (2) | AU2009300088B2 (es) |
BR (2) | BRPI0920791B8 (es) |
CA (9) | CA2936868C (es) |
CY (11) | CY1116302T1 (es) |
DK (12) | DK2172211T3 (es) |
EA (3) | EA023013B1 (es) |
ES (12) | ES2536465T3 (es) |
HK (2) | HK1159526A1 (es) |
HR (12) | HRP20201025T8 (es) |
HU (11) | HUE031030T2 (es) |
LT (10) | LT2172212T (es) |
MX (3) | MX2011003540A (es) |
NZ (4) | NZ624533A (es) |
PL (12) | PL2172211T3 (es) |
PT (12) | PT2172211E (es) |
RS (12) | RS53782B1 (es) |
SI (12) | SI2172211T1 (es) |
TR (2) | TR201900809T4 (es) |
UA (3) | UA110599C2 (es) |
WO (2) | WO2010037514A2 (es) |
Families Citing this family (107)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006023598A2 (en) | 2004-08-19 | 2006-03-02 | University Of Maryland, Baltimore | Prostate-specific antigen-derived mhc class ii-restricted peptides and their use in vaccines to treat or prevent prostate cancer |
WO2006034334A2 (en) | 2004-09-21 | 2006-03-30 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Peptide analogs capable of enhancing stimulation of a glioma-specific ctl response |
PT2660248E (pt) * | 2007-07-27 | 2015-10-12 | Immatics Biotechnologies Gmbh | Nova imunoterapia para tumores neuronais e cerebrais |
ATE462442T1 (de) * | 2008-04-30 | 2010-04-15 | Immatics Biotechnologies Gmbh | Neuartige formulierungen von tumor-assoziierten peptiden, welche an menschliche leukozytenantigene der klasse i oder ii für impfungen binden |
NO2119726T3 (es) | 2008-05-14 | 2015-05-23 | ||
EP2172211B1 (en) | 2008-10-01 | 2014-12-03 | Immatics Biotechnologies GmbH | Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers |
TW201124530A (en) * | 2009-12-01 | 2011-07-16 | Oncotherapy Science Inc | IMP-3 oligopeptides and vaccines including the same |
SE535982C2 (sv) * | 2009-12-15 | 2013-03-19 | Theravac Pharmaceuticals Ab | Ett nytt vaccin som angriper tumörkärl som ett effektivt redskap i tumörterapi |
GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
AU2015200751B2 (en) * | 2010-03-19 | 2016-11-10 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors including gastrointestinal and gastric cancer |
MX353165B (es) * | 2010-08-24 | 2017-12-20 | Univ Of Pittsburgh Of The Commonwealth System Of Higher Education Star | Vacunas contra el cancer cerebral basadas en peptido alfa 2 del receptor de interleucina 13. |
WO2012075490A2 (en) * | 2010-12-03 | 2012-06-07 | Duke University | Anti-podoplanin antibodies and methods of use |
NZ609916A (en) * | 2010-12-14 | 2015-03-27 | Immatics Biotechnologies Gmbh | Hla-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
WO2013052158A2 (en) * | 2011-04-26 | 2013-04-11 | William Marsh Rice University | Targeted nanovectors and their use for treatment of brain tumors |
ES2856091T3 (es) * | 2011-09-14 | 2021-09-27 | Univ Northwestern | Nanoconjugados capaces de atravesar la barrera hematoencefálica |
GB201120779D0 (en) * | 2011-12-02 | 2012-01-11 | Immodulon Therapeutics Ltd | Cancer therapy |
JP2015511936A (ja) * | 2012-01-20 | 2015-04-23 | ブラウン、デニス | 多形神経膠芽腫及び髄芽腫を含む新生物疾患及び癌幹細胞を処置するためのジアンヒドロガラクチトール及び類似体を含めた置換ヘキシトールの使用 |
US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
CN103372217B (zh) * | 2012-04-28 | 2014-12-10 | 中国科学院深圳先进技术研究院 | 聚合物纳米载体制剂及其制备方法和应用 |
DK3536334T3 (da) | 2012-05-16 | 2021-09-13 | Stemline Therapeutics Inc | Cancer stamcelle målrettede cancer vacciner |
CN112587658A (zh) * | 2012-07-18 | 2021-04-02 | 博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
TWI819228B (zh) * | 2013-08-05 | 2023-10-21 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(八) |
CN110041403B (zh) * | 2013-08-05 | 2023-03-10 | 伊玛提克斯生物技术有限公司 | 针对多种肿瘤例如包括nsclc在内的肺癌的新型免疫疗法 |
GB201319446D0 (en) | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
MX2019013161A (es) * | 2013-11-04 | 2020-02-03 | Immatics Biotechnologies Gmbh | Inmunoterapia personalizada contra diversos tumores cerebrales y neuronales. |
CN104698059B (zh) * | 2013-12-04 | 2017-07-21 | 苏州中赢医疗科技有限公司 | 一种脑胶质瘤肿瘤标志物及其应用 |
GB201322725D0 (en) | 2013-12-20 | 2014-02-05 | Immodulon Therapeutics Ltd | Cancer therapy |
US9725710B2 (en) | 2014-01-08 | 2017-08-08 | Flodesign Sonics, Inc. | Acoustophoresis device with dual acoustophoretic chamber |
KR101503341B1 (ko) * | 2014-03-12 | 2015-03-18 | 국립암센터 | 자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법 |
SG10201809379UA (en) | 2014-04-25 | 2018-11-29 | Bluebird Bio Inc | Mnd promoter chimeric antigen receptors |
JP6613526B2 (ja) * | 2014-05-28 | 2019-12-04 | 学校法人東京女子医科大学 | 膠芽腫の予測方法 |
JP2015227292A (ja) * | 2014-05-30 | 2015-12-17 | 国立大学法人高知大学 | 膵がん細胞浸潤転移抑制ワクチン |
US10479975B2 (en) | 2014-06-06 | 2019-11-19 | Bluebird Bio, Inc. | Methods of making T cell compositions |
JP6366379B2 (ja) * | 2014-06-20 | 2018-08-01 | キヤノン株式会社 | 被検体情報取得装置 |
CN106795217B (zh) | 2014-07-24 | 2021-08-06 | 蓝鸟生物公司 | Bcma嵌合抗原受体 |
KR102043725B1 (ko) * | 2014-11-06 | 2019-11-13 | 오제 이뮈노테라프틱스 | 뇌 전이 치료를 위한 치료용 다중 펩타이드 t 특이적 면역 요법 |
SG11201704727WA (en) | 2014-12-12 | 2017-07-28 | Bluebird Bio Inc | Bcma chimeric antigen receptors |
MD3236985T3 (ro) * | 2014-12-23 | 2023-03-31 | Immatics Biotechnologies Gmbh | Noi peptide și combinații de peptide pentru utilizare în imunoterapie împotriva carcinomului hepatocelular (HCC) și altor tipuri de cancere |
GB201501017D0 (en) * | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
GB201423361D0 (en) * | 2014-12-30 | 2015-02-11 | Immatics Biotechnologies Gmbh | Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides |
GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
GB201507719D0 (en) | 2015-05-06 | 2015-06-17 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers |
JP6985153B2 (ja) * | 2015-05-06 | 2021-12-22 | イマティクス バイオテクノロジーズ ゲーエムベーハー | 結腸直腸がん(crc)およびその他のがんに対する免疫療法で使用するための新規ペプチドおよびペプチドとそのスキャフォールドとの組み合わせ |
NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
WO2016200787A2 (en) | 2015-06-09 | 2016-12-15 | The Board Of Regents Of The University Of Oklahoma | Compositions and treatments for haemophilus influenzae |
MX2017016931A (es) | 2015-06-24 | 2018-09-26 | Immodulon Therapeutics Ltd | Inhibidor del punto de regulacion y un mycobaterium de celula entera para uso en la terapia del cancer. |
GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
PE20230321A1 (es) | 2015-07-01 | 2023-02-22 | Immatics Biotechnologies Gmbh | Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra el cancer de ovario y otros tipos de cancer |
CA3221001A1 (en) * | 2015-07-06 | 2017-01-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers |
GB201512369D0 (en) * | 2015-07-15 | 2015-08-19 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers |
GB201513921D0 (en) | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
TWI794761B (zh) | 2015-08-28 | 2023-03-01 | 德商英麥提克生物技術股份有限公司 | 用於多種癌症之免疫治療的新穎胜肽、胜肽的組合物及支架 |
GB201515321D0 (en) * | 2015-08-28 | 2015-10-14 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
EP3344276B1 (en) | 2015-09-03 | 2020-04-22 | The Board of Regents of the University of Oklahoma | Peptide inhibitors of clostridium difficile tcdb toxin |
CN108289909A (zh) | 2015-10-19 | 2018-07-17 | 巴尔的摩马里兰大学 | 用于产生工程改造的人原代血液树突细胞系的方法 |
US11479755B2 (en) | 2015-12-07 | 2022-10-25 | 2Seventy Bio, Inc. | T cell compositions |
GB201521746D0 (en) * | 2015-12-10 | 2016-01-27 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against CLL and other cancers |
CN108601731A (zh) | 2015-12-16 | 2018-09-28 | 磨石肿瘤生物技术公司 | 新抗原的鉴别、制造及使用 |
WO2017123996A1 (en) | 2016-01-15 | 2017-07-20 | City Of Hope | Targeting glioblastoma stem cells through the tlx-tet3 axis |
GB201603568D0 (en) * | 2016-03-01 | 2016-04-13 | Immatics Biotechnologies Gmbh | Efficient treatment options including peptides and combination of peptide and cell based medicaments for use in immunotherapy against urinary bladder cancer |
CN105664134B (zh) * | 2016-03-13 | 2019-04-26 | 浙江药苑生物科技有限公司 | 一种用于治疗骨癌的药物组合物 |
GB201604494D0 (en) | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Transfected T-Cells and T-Cell receptors for use in immunotherapy against cancers |
LT3430037T (lt) | 2016-03-16 | 2022-12-12 | Immatics Biotechnologies Gmbh | Transfekuotos t ląstelės ir t ląstelių receptoriai, skirti naudoti vėžio gydymui taikant imunoterapiją |
GB201604490D0 (en) * | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Peptides combination of peptides for use in immunotherapy against cancers |
BR112018070067A2 (pt) * | 2016-04-06 | 2019-02-12 | Immatics Biotechnologies Gmbh | peptídeos e combinações de peptídeos para uso em imunoterapia contra lma e outros cânceres |
US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
WO2017194170A1 (en) * | 2016-05-13 | 2017-11-16 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of proteins or protein fragments for immunotherapy |
KR101881300B1 (ko) | 2016-06-30 | 2018-07-25 | 영남대학교 산학협력단 | 아조피라졸 화합물 및 은 촉매 반응을 이용한 이의 신규한 합성방법 |
ES2950435T3 (es) * | 2016-10-03 | 2023-10-10 | Ottawa Hospital Res Inst | Composiciones y métodos para mejorar el crecimiento, la propagación y la eficacia oncolítica e inmunoterapéutica de virus oncolíticos de ARN |
MX2019005277A (es) | 2016-11-04 | 2019-09-27 | Bluebird Bio Inc | Composiciones de celulas t con car anti-bcma. |
DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
KR102639592B1 (ko) | 2016-12-08 | 2024-02-21 | 이매틱스 바이오테크놀로지스 게엠베하 | 짝짓기가 향상된 t 세포 수용체 |
AU2017379900A1 (en) * | 2016-12-22 | 2019-06-13 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
SG10201914064QA (en) | 2017-01-06 | 2020-03-30 | Eutilex Co Ltd | Anti-human 4-1 bb antibodies and use thereof |
GB201702863D0 (en) * | 2017-02-22 | 2017-04-05 | Evox Therapeutics Ltd | Improved loading of EVs with therapeutic proteins |
WO2018160498A1 (en) * | 2017-02-28 | 2018-09-07 | Lyten, Inc. | Mixed allotrope particulate carbon films and carbon fiber mats |
JP2020518648A (ja) * | 2017-05-08 | 2020-06-25 | グリットストーン オンコロジー インコーポレイテッド | アルファウイルス新生抗原ベクター |
CN107034305A (zh) * | 2017-06-19 | 2017-08-11 | 上海市第十人民医院 | 恶性胶质瘤的一种诊断标志物 |
CN107058596A (zh) * | 2017-06-19 | 2017-08-18 | 上海市第十人民医院 | 一种与恶性胶质瘤诊断相关的标志物及其应用 |
CA3078744A1 (en) | 2017-10-10 | 2019-04-18 | Gritstone Oncology, Inc. | Neoantigen identification using hotspots |
CA3083097A1 (en) | 2017-11-22 | 2019-05-31 | Gritstone Oncology, Inc. | Reducing junction epitope presentation for neoantigens |
WO2019118921A1 (en) | 2017-12-14 | 2019-06-20 | Flodesign Sonics, Inc. | Acoustic transducer drive and controller |
EP3724327A4 (en) * | 2017-12-14 | 2022-01-12 | EZY Biotech LLC | SUBJECT-SPECIFIC TUMOR-INHIBITING CELLS AND THEIR USE |
WO2019197567A2 (en) * | 2018-04-11 | 2019-10-17 | Enterome S.A. | Antigenic peptides for prevention and treatment of cancer |
CN108715832B (zh) * | 2018-06-01 | 2020-11-10 | 段海峰 | 一种抑制肿瘤生长的间充质干细胞及制备方法和应用 |
WO2020110154A1 (en) * | 2018-11-30 | 2020-06-04 | Bharat Biotech International Limited | A chimeric therapeutic vaccine |
RU2706554C1 (ru) * | 2018-12-13 | 2019-11-19 | Российская Федерация, от имени которой выступает ФОНД ПЕРСПЕКТИВНЫХ ИССЛЕДОВАНИЙ | Способ создания противоинфекционной иммунологической защиты к Salmonella typhimurium и Listeria monocytogenes с помощью трансгенеза Т-лимфоцитов |
CN109796536B (zh) * | 2019-02-22 | 2021-09-17 | 上海尚泰生物技术有限公司 | 一种靶向胶质母细胞瘤多种抗原表位的ctl的制备方法 |
JP2022527629A (ja) | 2019-04-05 | 2022-06-02 | アーリー・インコーポレイテッド | 合成バイオマーカーのための改良された方法及び組成物 |
US10937541B2 (en) | 2019-05-28 | 2021-03-02 | PAIGE.AI, Inc. | Systems and methods for processing images to prepare slides for processed images for digital pathology |
SG11202113187WA (en) | 2019-05-30 | 2021-12-30 | Gritstone Bio Inc | Modified adenoviruses |
CN110579457B (zh) * | 2019-09-20 | 2021-11-02 | 郑州大学第一附属医院 | 波形蛋白特异响应性荧光探针及其制备方法和应用 |
CN112824427B (zh) * | 2019-11-18 | 2022-06-24 | 杨小骏 | 一种抑制胶质瘤的短肽及其应用 |
CN113318225B (zh) * | 2020-02-28 | 2024-01-19 | 无锡派列博生物医药科技有限公司 | 肿瘤免疫增强剂及其制法和应用 |
CN113444149A (zh) * | 2020-03-18 | 2021-09-28 | 北京鼎成肽源生物技术有限公司 | 一种乳腺癌靶标抗原、乳腺癌靶标抗原刺激培养的ctl细胞及其应用 |
MX2022012295A (es) * | 2020-03-31 | 2023-03-06 | Walking Fish Therapeutics | Celulas b modificadas y metodos de uso de las mismas. |
EP4127188A4 (en) | 2020-03-31 | 2024-08-21 | Walking Fish Therapeutics | MODIFIED B CELLS AND METHODS OF USE THEREOF |
WO2022032196A2 (en) | 2020-08-06 | 2022-02-10 | Gritstone Bio, Inc. | Multiepitope vaccine cassettes |
KR102711471B1 (ko) | 2020-08-14 | 2024-09-30 | 서울대학교산학협력단 | B형 간염 바이러스 유래 폴리펩티드를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
CA3190707A1 (en) * | 2020-08-28 | 2022-03-03 | Torigen Pharmaceuticals, Inc. | Immune memory enhanced preparations and uses thereof |
US11058751B1 (en) | 2020-11-20 | 2021-07-13 | Think Therapeutics, Inc. | Compositions for optimized RAS peptide vaccines |
US11421015B2 (en) | 2020-12-07 | 2022-08-23 | Think Therapeutics, Inc. | Method of compact peptide vaccines using residue optimization |
US11464842B1 (en) | 2021-04-28 | 2022-10-11 | Think Therapeutics, Inc. | Compositions and method for optimized peptide vaccines using residue optimization |
WO2023192820A2 (en) * | 2022-03-30 | 2023-10-05 | Iogenetics, Llc | Tumor-associated antigens in brain tumors |
PL441229A1 (pl) * | 2022-05-19 | 2023-11-20 | Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk | Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych |
Family Cites Families (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4440859A (en) | 1977-05-27 | 1984-04-03 | The Regents Of The University Of California | Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms |
US4704362A (en) | 1977-11-08 | 1987-11-03 | Genentech, Inc. | Recombinant cloning vehicle microbial polypeptide expression |
ES487106A0 (es) | 1978-12-22 | 1981-05-16 | Biogen Nv | Un metodo para producir al menos un polipeptido que muestra antigenicidad de hbv |
US4530901A (en) | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
US4342566A (en) | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
US4678751A (en) | 1981-09-25 | 1987-07-07 | Genentech, Inc. | Hybrid human leukocyte interferons |
US4766075A (en) | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
US4582800A (en) | 1982-07-12 | 1986-04-15 | Hoffmann-La Roche Inc. | Novel vectors and method for controlling interferon expression |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4757006A (en) | 1983-10-28 | 1988-07-12 | Genetics Institute, Inc. | Human factor VIII:C gene and recombinant methods for production |
US4677063A (en) | 1985-05-02 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
US4810648A (en) | 1986-01-08 | 1989-03-07 | Rhone Poulenc Agrochimie | Haloarylnitrile degrading gene, its use, and cells containing the gene |
US4897445A (en) | 1986-06-27 | 1990-01-30 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide bond |
US5338839A (en) * | 1988-04-12 | 1994-08-16 | Massachusetts Institute Of Technology | DNA encoding nestin protein |
KR100235089B1 (en) | 1992-05-14 | 1999-12-15 | Mitsui Chemicals Inc | Ptp or blister packaging articles and packaging material therefor |
GB2267257A (en) | 1992-05-14 | 1993-12-01 | Ford Motor Co | A vehicle load compartment liner. |
ES2108460T3 (es) | 1993-06-03 | 1997-12-16 | Therapeutic Antibodies Inc | Fragmentos de anticuerpos en terapeutica. |
AUPM322393A0 (en) | 1993-12-24 | 1994-01-27 | Austin Research Institute, The | Mucin carbohydrate compounds and their use in immunotherapy |
PT879282E (pt) | 1996-01-17 | 2003-11-28 | Imp College Innovations Ltd | Imunoterapia utilizando linfocitos t citotoxicos (ctl) |
US5849589A (en) | 1996-03-11 | 1998-12-15 | Duke University | Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells |
IL120561A0 (en) * | 1996-04-24 | 1997-07-13 | Akzo Nobel Nv | Peptides suitable for use in immunosuppressive therapy |
EP0942748A4 (en) * | 1996-07-22 | 2004-12-08 | Univ Rockefeller | ENV-GLYCOPROTEIN VACCINE FOR PROTECTION AGAINST HTLV-I AND HTLV-II INFECTIONS |
AU6240798A (en) | 1997-01-15 | 1998-08-07 | Zymogenetics Inc. | Zppar6, human tailless nuclear hormone receptor (tlx receptor) |
JPH11507845A (ja) * | 1997-02-13 | 1999-07-13 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | 神経細胞付着分子スプライシング変種 |
US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
AU750358B2 (en) * | 1997-12-02 | 2002-07-18 | Medarex, Inc. | Cells expressing anti-Fc receptor binding components |
US7258860B2 (en) * | 1998-03-18 | 2007-08-21 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
AU3762699A (en) * | 1998-04-27 | 1999-11-16 | Pacific Northwest Cancer Foundation | (nr-cam) gene, nucleic acids and nucleic acid products for therapeutic and diagnostic uses for tumors |
US6960651B2 (en) * | 1999-06-29 | 2005-11-01 | Millennium Pharmaceuticals, Inc. | TANGO 332 polypeptides |
US20020090672A1 (en) * | 2000-01-31 | 2002-07-11 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
WO2001055208A1 (en) * | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
AU785493B2 (en) | 2000-03-27 | 2008-01-03 | Technion Research & Development Foundation Ltd. | Single chain class I major histo-compatibility complexes, constructs encoding same and methods of generating same |
US20040191260A1 (en) | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
AU2001279581A1 (en) * | 2000-09-06 | 2002-03-22 | Friederike Muller | Medicament comprising a dna sequence, which codes for the rna-binding koc protein, and comprising a koc protein or dna sequence of the koc promoter |
US7919467B2 (en) * | 2000-12-04 | 2011-04-05 | Immunotope, Inc. | Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
AU2002226030A1 (en) * | 2000-12-04 | 2002-06-18 | Argonex Pharmaceuticals | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
WO2002046767A2 (en) * | 2000-12-08 | 2002-06-13 | Oxford Glycosciences (Uk) Ltd. | Diagnosis and treatment of alzheimer's disease |
US20030109434A1 (en) * | 2001-03-19 | 2003-06-12 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of kidney cancer |
CA2364106A1 (fr) * | 2001-11-30 | 2003-05-30 | Christopher Gillberg | Polynucleotide et proteine impliques dans la synaptogenese, variants de ceux-ci, et leurs applications therapeutiques et diagnostiques |
US6589642B1 (en) | 2001-12-21 | 2003-07-08 | Kloeckner Pentaplast Of America, Inc. | Three part high moisture barrier for packages |
US7892559B2 (en) * | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
US6992176B2 (en) | 2002-02-13 | 2006-01-31 | Technion Research & Development Foundation Ltd. | Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease |
CA2476625A1 (en) | 2002-02-20 | 2003-08-28 | Dyax Corp. | Mhc-peptide complex binding ligands |
AU2003258134A1 (en) * | 2002-08-09 | 2004-02-25 | Applera Corporation | Lung cancer target proteins and use thereof |
JP4721633B2 (ja) * | 2002-10-11 | 2011-07-13 | 財団法人癌研究会 | 血小板凝集促進活性を有する物質 |
WO2004067029A1 (fr) * | 2002-12-27 | 2004-08-12 | Shenzhen Tsinghua Yuanxing Bio-Pharm Science & Technology Co., Ltd. | Procede de preparation d'un vaccin et vaccins antitumoraux |
US7273980B2 (en) | 2004-01-13 | 2007-09-25 | Wardle Scott A | Position and velocity transducer using a phonograph disc and turntable |
US7655751B2 (en) * | 2004-01-23 | 2010-02-02 | Green Peptide Co., Ltd. | Epidermal growth factor receptor-derived peptides |
DE102004026135A1 (de) * | 2004-05-25 | 2006-01-05 | Immatics Biotechnologies Gmbh | An MHC-Moleküle bindende Tumor-assoziierte Peptide |
US20080280317A1 (en) * | 2004-08-27 | 2008-11-13 | Northeastern University | Comprehensive Characterization Of Complex Proteins At Trace Levels |
DE602004019215D1 (de) * | 2004-10-02 | 2009-03-12 | Immatics Biotechnologies Gmbh | Immunogene T-Helfer Epitope von menschlichen Tumorantigenen und deren Verwendung in immunotherapeutischen Methoden |
US7902143B2 (en) * | 2004-12-07 | 2011-03-08 | Toray Industries, Inc. | Cancer antigen peptide and the use thereof |
KR100809410B1 (ko) * | 2005-07-06 | 2008-03-05 | 주식회사 브레인가드 | 줄기세포 분화 유도용 조성물 및 그의 용도 |
DK1760089T3 (da) * | 2005-09-05 | 2009-11-16 | Immatics Biotechnologies Gmbh | Tumor-associeret peptides bindende til human leukocyte antigen (HLA) class I eller II molecules og relateret anti-cancer vaccine |
DK1806359T3 (da) | 2005-09-05 | 2010-06-14 | Immatics Biotechnologies Gmbh | Tumorassocierede peptider, der bindes promiskuøst til Humant Leukocyt-Antigen (HLA) klasse II molekyler |
AU2006304605A1 (en) | 2005-10-17 | 2007-04-26 | Institute For Systems Biology | Tissue-and serum-derived glycoproteins and methods of their use |
US20070248628A1 (en) * | 2005-12-06 | 2007-10-25 | Keller Lorraine H | Immunogens in cancer stem cells |
WO2007072494A1 (en) | 2005-12-23 | 2007-06-28 | Naik Praful Ramchandra | Metallized packaging blister container |
CA2665816C (en) * | 2006-09-21 | 2016-07-12 | Vaxil Biotherapeutics Ltd. | Antigen specific multi epitope vaccines |
CA2700573C (en) * | 2006-09-26 | 2016-11-22 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
CA2679743A1 (en) * | 2007-03-06 | 2008-09-12 | Barry G. Arnason | Methods and compositions involving polymeric immunoglobulin fusion proteins |
US8747855B2 (en) * | 2008-04-09 | 2014-06-10 | Technion Research & Development Foundation Limited | Anti human immunodeficiency antibodies and uses thereof |
KR101184869B1 (ko) * | 2008-04-24 | 2012-09-20 | 이매틱스 바이오테크놀로지스 게엠베하 | 백신을 위한 인간 조직 적합성 항원(hla) 종류 i 또는 ii 분자에 결합하는 종양 관련 펩티드의 신규한 제형 |
ATE462442T1 (de) * | 2008-04-30 | 2010-04-15 | Immatics Biotechnologies Gmbh | Neuartige formulierungen von tumor-assoziierten peptiden, welche an menschliche leukozytenantigene der klasse i oder ii für impfungen binden |
EP2172211B1 (en) | 2008-10-01 | 2014-12-03 | Immatics Biotechnologies GmbH | Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers |
GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
GB201021289D0 (en) | 2010-12-15 | 2011-01-26 | Immatics Biotechnologies Gmbh | Novel biomarkers for a prediction of the outcome of an immunotherapy against cancer |
MX2016015457A (es) * | 2014-05-28 | 2017-06-30 | Nono Inc | Sal de cloruro de tat-nr2b9c. |
AU2017253549B2 (en) * | 2016-04-21 | 2021-01-21 | Immatics Biotechnologies Gmbh | Immunotherapy against melanoma and other cancers |
JP7382310B2 (ja) * | 2017-09-06 | 2023-11-16 | カリフォルニア インスティチュート オブ テクノロジー | シグナリング及び抗原提示の2機能性レセプター(sabr) |
-
2008
- 2008-10-01 EP EP20080017305 patent/EP2172211B1/en active Active
- 2008-10-01 PL PL08017305T patent/PL2172211T3/pl unknown
- 2008-10-01 PT PT80173057T patent/PT2172211E/pt unknown
- 2008-10-01 DK DK08017305T patent/DK2172211T3/en active
- 2008-10-01 RS RS20150094A patent/RS53782B1/en unknown
- 2008-10-01 SI SI200831373T patent/SI2172211T1/sl unknown
- 2008-10-01 ES ES08017305.7T patent/ES2536465T3/es active Active
- 2008-10-13 DK DK08017921.1T patent/DK2172212T3/da active
- 2008-10-13 SI SI200831695A patent/SI2172212T1/sl unknown
- 2008-10-13 RS RS20161019A patent/RS55543B1/sr unknown
- 2008-10-13 HU HUE08017921A patent/HUE031030T2/en unknown
- 2008-10-13 LT LTEP08017921.1T patent/LT2172212T/lt unknown
- 2008-10-13 ES ES08017921.1T patent/ES2607460T3/es active Active
- 2008-10-13 EP EP08017921.1A patent/EP2172212B1/en active Active
- 2008-10-13 PT PT80179211T patent/PT2172212T/pt unknown
- 2008-10-13 PL PL08017921T patent/PL2172212T3/pl unknown
-
2009
- 2009-09-28 PL PL16179169T patent/PL3132801T3/pl unknown
- 2009-09-28 CN CN201610831523.XA patent/CN106986919A/zh active Pending
- 2009-09-28 CA CA2936868A patent/CA2936868C/en active Active
- 2009-09-28 CA CA2936982A patent/CA2936982C/en active Active
- 2009-09-28 MX MX2011003540A patent/MX2011003540A/es active IP Right Grant
- 2009-09-28 HU HUE16179241A patent/HUE042115T2/hu unknown
- 2009-09-28 HR HRP20201025TT patent/HRP20201025T8/hr unknown
- 2009-09-28 ES ES16179174T patent/ES2804723T3/es active Active
- 2009-09-28 UA UAA201103611A patent/UA110599C2/uk unknown
- 2009-09-28 DK DK16179241.1T patent/DK3111952T3/en active
- 2009-09-28 CA CA2936920A patent/CA2936920C/en active Active
- 2009-09-28 CA CA2936924A patent/CA2936924C/en active Active
- 2009-09-28 CA CA2936869A patent/CA2936869C/en active Active
- 2009-09-28 PT PT97787493T patent/PT2331118T/pt unknown
- 2009-09-28 PL PL16179214T patent/PL3124043T3/pl unknown
- 2009-09-28 PL PL16179163T patent/PL3106175T3/pl unknown
- 2009-09-28 DK DK16179192.6T patent/DK3120869T3/da active
- 2009-09-28 EP EP16179192.6A patent/EP3120869B1/en active Active
- 2009-09-28 RS RS20200692A patent/RS60385B1/sr unknown
- 2009-09-28 PT PT161791694T patent/PT3132801T/pt unknown
- 2009-09-28 EP EP16179241.1A patent/EP3111952B1/en active Active
- 2009-09-28 ES ES09778750.1T patent/ES2584245T3/es active Active
- 2009-09-28 BR BRPI0920791A patent/BRPI0920791B8/pt active IP Right Grant
- 2009-09-28 RS RS20161160A patent/RS55531B1/sr unknown
- 2009-09-28 SI SI200932065T patent/SI3120868T1/sl unknown
- 2009-09-28 PT PT16179241T patent/PT3111952T/pt unknown
- 2009-09-28 EP EP16179174.4A patent/EP3120868B1/en active Active
- 2009-09-28 EA EA201100586A patent/EA023013B1/ru unknown
- 2009-09-28 PL PL09778749T patent/PL2331118T3/pl unknown
- 2009-09-28 SI SI200932083T patent/SI3120869T1/sl unknown
- 2009-09-28 PT PT161792148T patent/PT3124043T/pt unknown
- 2009-09-28 PT PT97787501T patent/PT2341927T/pt unknown
- 2009-09-28 HU HUE16179163A patent/HUE049367T2/hu unknown
- 2009-09-28 ES ES16179169T patent/ES2770090T3/es active Active
- 2009-09-28 HU HUE16165070A patent/HUE041446T2/hu unknown
- 2009-09-28 PT PT16165070T patent/PT3069728T/pt unknown
- 2009-09-28 CA CA2739384A patent/CA2739384C/en not_active Expired - Fee Related
- 2009-09-28 RS RS20181585A patent/RS58229B1/sr unknown
- 2009-09-28 CA CA2936870A patent/CA2936870C/en active Active
- 2009-09-28 LT LTEP09778749.3T patent/LT2331118T/lt unknown
- 2009-09-28 CN CN200980139419.2A patent/CN102170900B/zh active Active
- 2009-09-28 PL PL16179192T patent/PL3120869T3/pl unknown
- 2009-09-28 LT LTEP16165070.0T patent/LT3069728T/lt unknown
- 2009-09-28 DK DK09778750.1T patent/DK2341927T3/en active
- 2009-09-28 RS RS20200691A patent/RS60381B1/sr unknown
- 2009-09-28 LT LTEP16179174.4T patent/LT3120868T/lt unknown
- 2009-09-28 RS RS20200973A patent/RS60656B1/sr unknown
- 2009-09-28 JP JP2011529472A patent/JP5855940B2/ja not_active Expired - Fee Related
- 2009-09-28 EP EP16179163.7A patent/EP3106175B1/en active Active
- 2009-09-28 NZ NZ624533A patent/NZ624533A/en unknown
- 2009-09-28 HU HUE09778750A patent/HUE029360T2/en unknown
- 2009-09-28 PL PL16179241T patent/PL3111952T3/pl unknown
- 2009-09-28 KR KR1020207019579A patent/KR102392070B1/ko active IP Right Grant
- 2009-09-28 JP JP2011529471A patent/JP5753783B2/ja not_active Expired - Fee Related
- 2009-09-28 RS RS20190118A patent/RS58443B1/sr unknown
- 2009-09-28 SI SI200931573A patent/SI2331118T1/sl unknown
- 2009-09-28 ES ES16179192T patent/ES2819244T3/es active Active
- 2009-09-28 RS RS20200085A patent/RS60006B1/sr unknown
- 2009-09-28 EA EA201401104A patent/EA032437B1/ru unknown
- 2009-09-28 PL PL09778750.1T patent/PL2341927T3/pl unknown
- 2009-09-28 UA UAA201500916A patent/UA125277C2/uk unknown
- 2009-09-28 WO PCT/EP2009/006980 patent/WO2010037514A2/en active Application Filing
- 2009-09-28 ES ES16179226T patent/ES2802227T3/es active Active
- 2009-09-28 ES ES16165070T patent/ES2710608T3/es active Active
- 2009-09-28 SI SI200932064T patent/SI3120870T1/sl unknown
- 2009-09-28 SI SI200931902T patent/SI3111952T1/sl unknown
- 2009-09-28 NZ NZ591855A patent/NZ591855A/xx unknown
- 2009-09-28 RS RS20200693A patent/RS60386B1/sr unknown
- 2009-09-28 ES ES16179241T patent/ES2708654T3/es active Active
- 2009-09-28 EP EP16165070.0A patent/EP3069728B1/en active Active
- 2009-09-28 NZ NZ603016A patent/NZ603016A/en not_active IP Right Cessation
- 2009-09-28 MX MX2012012047A patent/MX338294B/es unknown
- 2009-09-28 EP EP16179226.2A patent/EP3120870B1/en active Active
- 2009-09-28 RS RS20200512A patent/RS60338B1/sr unknown
- 2009-09-28 EP EP16179169.4A patent/EP3132801B1/en active Active
- 2009-09-28 LT LTEP16179214.8T patent/LT3124043T/lt unknown
- 2009-09-28 EP EP16179214.8A patent/EP3124043B1/en active Active
- 2009-09-28 EA EA201100587A patent/EA023378B1/ru unknown
- 2009-09-28 HU HUE16179192A patent/HUE050428T2/hu unknown
- 2009-09-28 CN CN200980139420.5A patent/CN102170901B/zh not_active Expired - Fee Related
- 2009-09-28 AU AU2009300088A patent/AU2009300088B2/en not_active Ceased
- 2009-09-28 HU HUE16179169A patent/HUE047365T2/hu unknown
- 2009-09-28 LT LTEP16179192.6T patent/LT3120869T/lt unknown
- 2009-09-28 SI SI200931464A patent/SI2341927T1/sl unknown
- 2009-09-28 SI SI200932034T patent/SI3132801T1/sl unknown
- 2009-09-28 LT LTEP16179226.2T patent/LT3120870T/lt unknown
- 2009-09-28 ES ES09778749.3T patent/ES2612466T3/es active Active
- 2009-09-28 DK DK09778749.3T patent/DK2331118T5/da active
- 2009-09-28 PL PL16179226T patent/PL3120870T3/pl unknown
- 2009-09-28 KR KR1020117010000A patent/KR101687840B1/ko active IP Right Grant
- 2009-09-28 TR TR2019/00809T patent/TR201900809T4/tr unknown
- 2009-09-28 PT PT161791744T patent/PT3120868T/pt unknown
- 2009-09-28 DK DK16179163.7T patent/DK3106175T3/da active
- 2009-09-28 PL PL16179174T patent/PL3120868T3/pl unknown
- 2009-09-28 TR TR2019/00852T patent/TR201900852T4/tr unknown
- 2009-09-28 KR KR1020167022929A patent/KR101883426B1/ko active IP Right Grant
- 2009-09-28 SI SI200932063T patent/SI3106175T1/sl unknown
- 2009-09-28 MX MX2011003539A patent/MX2011003539A/es active IP Right Grant
- 2009-09-28 KR KR1020117010003A patent/KR101756488B1/ko active IP Right Grant
- 2009-09-28 NZ NZ591882A patent/NZ591882A/xx not_active IP Right Cessation
- 2009-09-28 PL PL16165070T patent/PL3069728T3/pl unknown
- 2009-09-28 UA UAA201103612A patent/UA103202C2/ru unknown
- 2009-09-28 DK DK16179169.4T patent/DK3132801T3/da active
- 2009-09-28 PT PT161791637T patent/PT3106175T/pt unknown
- 2009-09-28 DK DK16179226.2T patent/DK3120870T3/da active
- 2009-09-28 CA CA2936887A patent/CA2936887C/en active Active
- 2009-09-28 HU HUE16179226A patent/HUE049364T2/hu unknown
- 2009-09-28 AU AU2009300087A patent/AU2009300087B2/en not_active Ceased
- 2009-09-28 DK DK16179174.4T patent/DK3120868T3/da active
- 2009-09-28 WO PCT/EP2009/006979 patent/WO2010037513A1/en active Application Filing
- 2009-09-28 LT LTEP16179241.1T patent/LT3111952T/lt unknown
- 2009-09-28 ES ES16179214T patent/ES2788129T3/es active Active
- 2009-09-28 EP EP09778750.1A patent/EP2341927B1/en active Active
- 2009-09-28 HU HUE09778749A patent/HUE030296T2/en unknown
- 2009-09-28 LT LTEP16179163.7T patent/LT3106175T/lt unknown
- 2009-09-28 PT PT161791926T patent/PT3120869T/pt unknown
- 2009-09-28 HU HUE16179174A patent/HUE049366T2/hu unknown
- 2009-09-28 RS RS20160553A patent/RS55043B1/sr unknown
- 2009-09-28 HU HUE16179214A patent/HUE051030T2/hu unknown
- 2009-09-28 SI SI200931921T patent/SI3069728T1/sl unknown
- 2009-09-28 KR KR1020227013879A patent/KR20220058655A/ko not_active Application Discontinuation
- 2009-09-28 CA CA2739387A patent/CA2739387C/en active Active
- 2009-09-28 BR BRPI0920759A patent/BRPI0920759A2/pt not_active Application Discontinuation
- 2009-09-28 LT LTEP16179169.4T patent/LT3132801T/lt unknown
- 2009-09-28 SI SI200932056T patent/SI3124043T1/sl unknown
- 2009-09-28 ES ES16179163T patent/ES2802226T3/es active Active
- 2009-09-28 PT PT161792262T patent/PT3120870T/pt unknown
- 2009-09-28 EP EP09778749.3A patent/EP2331118B1/en active Active
- 2009-09-28 KR KR1020187021349A patent/KR102133402B1/ko active IP Right Grant
- 2009-09-28 DK DK16179214.8T patent/DK3124043T3/da active
- 2009-09-28 DK DK16165070.0T patent/DK3069728T3/en active
- 2009-10-01 US US12/571,776 patent/US8119139B2/en active Active
- 2009-10-01 US US12/571,602 patent/US8318677B2/en active Active
-
2012
- 2012-01-09 US US13/346,598 patent/US8961985B2/en active Active
- 2012-01-10 HK HK12100262.7A patent/HK1159526A1/zh unknown
- 2012-02-21 HK HK12101677.4A patent/HK1161106A1/xx not_active IP Right Cessation
- 2012-08-17 US US13/588,206 patent/US8653035B2/en active Active
-
2013
- 2013-03-15 US US13/841,013 patent/US8895514B2/en active Active
-
2014
- 2014-06-19 JP JP2014126001A patent/JP5883476B2/ja active Active
- 2014-12-05 US US14/562,156 patent/US10227381B2/en active Active
-
2015
- 2015-02-12 CY CY20151100139T patent/CY1116302T1/el unknown
- 2015-02-26 HR HRP20150223TT patent/HRP20150223T8/hr unknown
- 2015-10-08 JP JP2015200021A patent/JP6150859B2/ja active Active
-
2016
- 2016-02-05 JP JP2016021002A patent/JP6214066B2/ja not_active Expired - Fee Related
- 2016-07-11 JP JP2016136518A patent/JP6294914B2/ja active Active
- 2016-07-11 JP JP2016136517A patent/JP6294913B2/ja active Active
- 2016-07-11 JP JP2016136515A patent/JP6367266B2/ja active Active
- 2016-07-11 JP JP2016136516A patent/JP2017029135A/ja active Pending
- 2016-07-11 JP JP2016136519A patent/JP6297632B2/ja active Active
- 2016-07-20 HR HRP20160915TT patent/HRP20160915T1/hr unknown
- 2016-08-02 US US15/226,206 patent/US10047124B2/en active Active
- 2016-08-02 CY CY20161100759T patent/CY1119744T1/el unknown
- 2016-08-02 US US15/226,126 patent/US10919931B2/en active Active
- 2016-08-02 US US15/226,161 patent/US10941181B2/en active Active
- 2016-08-02 US US15/226,038 patent/US10100085B2/en active Active
- 2016-08-02 US US15/226,098 patent/US10906936B2/en active Active
- 2016-08-02 US US15/226,081 patent/US10046037B2/en active Active
- 2016-08-02 US US15/226,002 patent/US10047123B2/en active Active
- 2016-11-15 HR HRP20161504TT patent/HRP20161504T1/hr unknown
-
2017
- 2017-01-24 HR HRP20170115TT patent/HRP20170115T1/hr unknown
- 2017-01-26 CY CY20171100124T patent/CY1118702T1/el unknown
- 2017-06-30 US US15/638,806 patent/US9993540B2/en active Active
-
2018
- 2018-09-19 US US16/136,008 patent/US20190010190A1/en not_active Abandoned
- 2018-12-18 HR HRP20182151TT patent/HRP20182151T1/hr unknown
- 2018-12-28 CY CY181101403T patent/CY1121098T1/el unknown
-
2019
- 2019-01-31 HR HRP20190202TT patent/HRP20190202T1/hr unknown
- 2019-02-12 CY CY20191100182T patent/CY1121258T1/el unknown
-
2020
- 2020-01-23 HR HRP20200110TT patent/HRP20200110T1/hr unknown
- 2020-01-28 CY CY20201100073T patent/CY1122677T1/el unknown
- 2020-05-05 HR HRP20200722TT patent/HRP20200722T1/hr unknown
- 2020-05-15 CY CY20201100449T patent/CY1122913T1/el unknown
- 2020-06-19 HR HRP20200988TT patent/HRP20200988T1/hr unknown
- 2020-06-26 CY CY20201100594T patent/CY1123089T1/el unknown
- 2020-06-26 HR HRP20201015TT patent/HRP20201015T8/hr unknown
- 2020-06-30 CY CY20201100606T patent/CY1123098T1/el unknown
- 2020-07-03 CY CY20201100613T patent/CY1123113T1/el unknown
- 2020-08-06 HR HRP20201228TT patent/HRP20201228T1/hr unknown
- 2020-10-19 CY CY20201100984T patent/CY1123526T1/el unknown
-
2021
- 2021-04-23 US US17/238,840 patent/US11136352B2/en active Active
- 2021-04-23 US US17/238,806 patent/US20210238227A1/en active Pending
- 2021-04-23 US US17/238,787 patent/US20210261614A1/en active Pending
- 2021-07-23 US US17/384,152 patent/US11208434B2/en active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2788129T8 (es) | Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales | |
BRPI0813621A2 (pt) | imunoterapia contra tumores neuronais e cerebrais |