PL441229A1 - Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych - Google Patents

Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych

Info

Publication number
PL441229A1
PL441229A1 PL441229A PL44122922A PL441229A1 PL 441229 A1 PL441229 A1 PL 441229A1 PL 441229 A PL441229 A PL 441229A PL 44122922 A PL44122922 A PL 44122922A PL 441229 A1 PL441229 A1 PL 441229A1
Authority
PL
Poland
Prior art keywords
treatment
methods
compositions containing
synthetic peptides
malignant gliomas
Prior art date
Application number
PL441229A
Other languages
English (en)
Inventor
Katarzyna POLESZAK
Maria Pasierbińska
Aleksandra ELLERT-MIKLASZEWSKA
Paulina PILANC-KUDLEK
Paweł Wiśniewski
Bożena Kamińska-Kaczmarek
Original Assignee
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk filed Critical Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk
Priority to PL441229A priority Critical patent/PL441229A1/pl
Priority to PCT/IB2023/055089 priority patent/WO2023223241A1/en
Priority to EP23738110.8A priority patent/EP4525904A1/en
Priority to US18/858,620 priority patent/US20250282829A1/en
Publication of PL441229A1 publication Critical patent/PL441229A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Przedmiotem zgłoszenia są zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania do leczenia nowotworów infiltrowanych makrofagami, takich jak złośliwe glejaki.
PL441229A 2022-05-19 2022-05-19 Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych PL441229A1 (pl)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PL441229A PL441229A1 (pl) 2022-05-19 2022-05-19 Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych
PCT/IB2023/055089 WO2023223241A1 (en) 2022-05-19 2023-05-17 Engineered synthetic peptides, compositions comprising same, and methods of use thereof for treating malignant gliomas
EP23738110.8A EP4525904A1 (en) 2022-05-19 2023-05-17 Engineered synthetic peptides, compositions comprising same, and methods of use thereof for treating malignant gliomas
US18/858,620 US20250282829A1 (en) 2022-05-19 2023-05-17 Engineered synthetic peptides, compositions comprising same, and methods of use thereof for treating malignant gliomas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL441229A PL441229A1 (pl) 2022-05-19 2022-05-19 Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych

Publications (1)

Publication Number Publication Date
PL441229A1 true PL441229A1 (pl) 2023-11-20

Family

ID=87136749

Family Applications (1)

Application Number Title Priority Date Filing Date
PL441229A PL441229A1 (pl) 2022-05-19 2022-05-19 Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych

Country Status (4)

Country Link
US (1) US20250282829A1 (pl)
EP (1) EP4525904A1 (pl)
PL (1) PL441229A1 (pl)
WO (1) WO2023223241A1 (pl)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110166072A1 (en) * 2006-12-26 2011-07-07 Woei-Jer Chuang Polypeptides Selective for avB3 Integrin, Including Pegylated Polypeptides, And Pharmaceutical Uses Thereof
WO2013072901A2 (en) * 2011-11-17 2013-05-23 Btm Mazowsze Sp. Zo.O. Compositions and methods for treating glioma
WO2020110117A1 (en) * 2018-11-28 2020-06-04 Glia Sp. Z O.O. Compositions and methods for treating glioma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2172211T3 (pl) * 2008-10-01 2015-05-29 Immatics Biotechnologies Gmbh Kompozycja związanych z guzem peptydów i związana z tym szczepionka przeciwrakowa do leczenia glejaka (GBM) i innych rodzajów raka

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110166072A1 (en) * 2006-12-26 2011-07-07 Woei-Jer Chuang Polypeptides Selective for avB3 Integrin, Including Pegylated Polypeptides, And Pharmaceutical Uses Thereof
WO2013072901A2 (en) * 2011-11-17 2013-05-23 Btm Mazowsze Sp. Zo.O. Compositions and methods for treating glioma
WO2020110117A1 (en) * 2018-11-28 2020-06-04 Glia Sp. Z O.O. Compositions and methods for treating glioma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ATAI NA, BANSAL M, LO C, BOSMAN J, TIGCHELAAR W, BOSCH KS, JONKER A, DE WITT HAMER PC, TROOST D, MCCULLOCH CA, EVERTS V, VAN NOORD: "Immunology. 2011 Jan;132(1):39-48.", OSTEOPONTIN IS UP-REGULATED AND ASSOCIATED WITH NEUTROPHIL AND MACROPHAGE INFILTRATION IN GLIOBLASTOMA. *
PILANC-KUDLEK P, POLESZAK K, ELLERT-MIKLASZEWSKA A, ET AL.: "Journal for ImmunoTherapy of Cancer 2021;9", 615 REACTIVATING ANTITUMOR IMMUNITY IN GLIOMAS WITH OSTEOPONTIN/INTEGRIN BLOCKING PEPTIDE *

Also Published As

Publication number Publication date
EP4525904A1 (en) 2025-03-26
WO2023223241A1 (en) 2023-11-23
US20250282829A1 (en) 2025-09-11

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