ES2290436T3 - Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies. - Google Patents

Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies. Download PDF

Info

Publication number
ES2290436T3
ES2290436T3 ES03709767T ES03709767T ES2290436T3 ES 2290436 T3 ES2290436 T3 ES 2290436T3 ES 03709767 T ES03709767 T ES 03709767T ES 03709767 T ES03709767 T ES 03709767T ES 2290436 T3 ES2290436 T3 ES 2290436T3
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
formula
baselineskip
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03709767T
Other languages
English (en)
Spanish (es)
Inventor
Sophie Marquais-Bienewald
Werner Holzl
Wolfgang Haap
Andrea Preuss
Andreas Mehlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba Spezialitaetenchemie Holding AG
Ciba SC Holding AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Spezialitaetenchemie Holding AG, Ciba SC Holding AG filed Critical Ciba Spezialitaetenchemie Holding AG
Application granted granted Critical
Publication of ES2290436T3 publication Critical patent/ES2290436T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/541,3-Diazines; Hydrogenated 1,3-diazines
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/781,3-Thiazoles; Hydrogenated 1,3-thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Paints Or Removers (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
ES03709767T 2002-03-15 2003-03-10 Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies. Expired - Lifetime ES2290436T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02405201 2002-03-15
EP02405201 2002-03-15

Publications (1)

Publication Number Publication Date
ES2290436T3 true ES2290436T3 (es) 2008-02-16

Family

ID=27838195

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03709767T Expired - Lifetime ES2290436T3 (es) 2002-03-15 2003-03-10 Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies.

Country Status (9)

Country Link
US (1) US7731985B2 (https=)
EP (1) EP1484971B1 (https=)
JP (1) JP2005520821A (https=)
CN (1) CN1642422A (https=)
AT (1) ATE366045T1 (https=)
AU (1) AU2003214110A1 (https=)
DE (1) DE60314730T2 (https=)
ES (1) ES2290436T3 (https=)
WO (1) WO2003077656A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037916B2 (en) * 1999-07-15 2006-05-02 Pharmacopeia Drug Discovery, Inc. Pyrimidine derivatives as IL-8 receptor antagonists
MXPA05007485A (es) * 2003-01-14 2006-01-30 Arena Pharm Inc Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia.
SI1599468T1 (sl) 2003-01-14 2008-02-29 Arena Pharm Inc 1,2,3-trisubstituirani arilni in heteroarilni derivati kot modulatorji metabolizma ter profilaksa in zdravljenje motenj v zvezi z njim, kot diabetesain hiperglikemije
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
JP2007506746A (ja) 2003-09-24 2007-03-22 ワイス・ホールディングズ・コーポレイション 抗癌剤としての5−アリールピリミジン類
GB0323137D0 (en) 2003-10-03 2003-11-05 Chang Lisa C W 2,4,6- Trisubstituted pyrimidines and their different uses
WO2005099711A1 (en) * 2004-04-13 2005-10-27 Icagen, Inc. Polycyclic pyrimidines as potassium ion channel modulators
PH12013500547A1 (en) 2010-09-22 2013-06-10 Arena Pharm Inc Modulators of the gpr119 receptor and the treatment of disorders related thereto
JP6116554B2 (ja) * 2011-07-07 2017-04-19 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung がんの処置のための置換されたアザ複素環
AR090880A1 (es) 2012-04-30 2014-12-10 Janssen R & D Ireland Derivados de pirimidina
CA2896731A1 (en) 2012-12-28 2014-07-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Inhibitors of the usp1/uaf1 deubiquitinase complex and uses thereof
MX386419B (es) 2015-01-06 2025-03-18 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
EP3939965A1 (en) 2015-06-22 2022-01-19 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in sipi receptor-associated disorders
MA47504A (fr) 2017-02-16 2019-12-25 Arena Pharm Inc Composés et méthodes de traitement de l'angiocholite biliaire primitive
CA3058813A1 (en) * 2017-04-05 2018-10-11 University Of Utah Research Foundation Compositions and methods comprising a triaryl polyamine
CN108162528B (zh) * 2017-12-22 2020-07-10 宿迁市金田塑业有限公司 一种新型高性能抗菌防雾膜
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1
US11993580B1 (en) 2022-12-02 2024-05-28 Neumora Therapeutics, Inc. Methods of treating neurological disorders

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143167A (en) * 1967-01-25 1969-02-19 Ucb Sa Derivatives of pyrimidine
US3755583A (en) * 1970-06-05 1973-08-28 Chas0!nhx
US3707560A (en) * 1970-10-05 1972-12-26 Pfizer Certain 4-amino-6-aryl-pyrimidines
DE2202385A1 (de) * 1972-01-19 1973-07-26 Boehringer Mannheim Gmbh Nitrofuran-derivate
US4144338A (en) * 1977-02-17 1979-03-13 Merck & Co., Inc. N-pyrimidinyl-N-dialkylaminoalkyl ureas
JPS6059883B2 (ja) * 1978-05-08 1985-12-27 北興化学工業株式会社 農園芸用殺菌剤
MA18829A1 (fr) * 1979-05-18 1980-12-31 Ciba Geigy Ag Derives de la pyrimidine,procedes pour leur preparation,compositions pharmaceutiques contenant ces composes et leur utilisation therapeutique
JPS57126481A (en) * 1981-01-29 1982-08-06 Sankyo Co Ltd Aminopyrimidine derivative, fungicide, insecticide, and acaricide
PH20344A (en) * 1981-01-29 1986-12-04 Sankyo Co Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them
JPS57176967A (en) * 1981-04-21 1982-10-30 Sankyo Co Ltd Aminopyrimidine derivative and antibacterial, insecticidal and miticidal agent
JPS5936666A (ja) * 1982-07-23 1984-02-28 Sankyo Co Ltd アミノピリミジン誘導体
EP0136976A3 (de) * 1983-08-23 1985-05-15 Ciba-Geigy Ag Verwendung von Phenylpyrimidinen als Pflanzenregulatoren
GB8417852D0 (en) * 1984-07-13 1984-08-15 Fujisawa Pharmaceutical Co Pyrimidine derivatives
DE3642452A1 (de) * 1986-12-12 1988-06-23 Bayer Ag Substituierte 4-amino-pyrimidine
JPH01250363A (ja) * 1987-12-28 1989-10-05 Kumiai Chem Ind Co Ltd 4―ベンジルアミノピリミジン誘導体及び除草剤
JPH0745481B2 (ja) * 1988-01-07 1995-05-17 宇部興産株式会社 アルキルアミノピリミジン誘導体、その製造法ならびに該誘導体を有効成分とする殺虫剤、殺ダニ剤および殺菌剤
US4931455A (en) * 1988-01-07 1990-06-05 Ube Industries, Ltd. Alkylaminopyrimidine derivative and insecticide, acaricide and fungicide containing the same as active ingredient
DE3922735A1 (de) * 1989-07-11 1991-01-24 Hoechst Ag Aminopyrimidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide
JPH0368563A (ja) * 1989-08-09 1991-03-25 Kumiai Chem Ind Co Ltd (S)―α―メチルベンジルアミノピリミジン誘導体及び除草剤
EP0424125A3 (en) * 1989-10-18 1991-10-09 Ube Industries, Ltd. Aralkylamine derivatives, preparation method thereof and fungicides containing the same
US5589477A (en) * 1990-08-31 1996-12-31 Nippon Shinyaku Company, Limited Pyrimidine derivatives and drugs
DE4031798A1 (de) * 1990-10-08 1992-04-09 Hoechst Ag Pyridylpyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide
DE4034762A1 (de) * 1990-11-02 1992-05-07 Hoechst Ag Pyridylpyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide
ATE176226T1 (de) * 1990-11-19 1999-02-15 Du Pont Insektizide, akarizide und fungizide aminopyrimidine
EP0519211A1 (de) * 1991-05-17 1992-12-23 Hoechst Schering AgrEvo GmbH Substituierte 4-Aminopyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
JPH05194418A (ja) * 1992-01-23 1993-08-03 Kirin Brewery Co Ltd 2−アミノピリミジン誘導体及びその用途
JP3086316B2 (ja) * 1992-01-31 2000-09-11 アグロカネショウ株式会社 フェニルカーバメート誘導体、その製造法及び該誘導体を有効成分とする農園芸用殺菌剤
JP2649119B2 (ja) * 1992-04-21 1997-09-03 宇部興産株式会社 アルキルアミノピリミジン化合物、その製法及び有害生物防除剤
US5354738A (en) * 1992-09-04 1994-10-11 G. D. Searle & Co. Platelet aggregation inhibitors
AU7551894A (en) 1993-09-09 1995-03-27 E.I. Du Pont De Nemours And Company Fungicidal, miticidal and arthropodicidal aminopyrimidines
AU7938994A (en) * 1993-10-25 1995-05-22 Shell Internationale Research Maatschappij B.V. Pyrimidine derivatives
JPH08283246A (ja) * 1994-06-01 1996-10-29 Nippon Soda Co Ltd ピリミジン誘導体、その製造方法及び有害生物防除剤
DE19511562A1 (de) * 1995-03-29 1996-10-02 Hoechst Schering Agrevo Gmbh Cyclohexylamino- und alkoxy-Stickstoff-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel und Fungizide
DE19600934A1 (de) * 1996-01-12 1997-07-17 Basf Ag Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung
US6011029A (en) * 1996-02-26 2000-01-04 Bristol-Myers Squibb Company Inhibitors of farnesyl protein transferase
DE19613329A1 (de) * 1996-04-03 1997-10-09 Hoechst Schering Agrevo Gmbh Substituierte Pyridine/Pyrimidine, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
JPH10130149A (ja) * 1996-07-12 1998-05-19 Sankyo Co Ltd Tnf産生抑制剤
JPH11246528A (ja) * 1997-12-05 1999-09-14 Tomono Agrica Co Ltd 含窒素芳香族化合物およびその塩
PT1091957E (pt) 1998-05-23 2005-05-31 Altana Pharma Ag Derivados de pirimidino-aminometil-piridina, sua preparacao e sua utilizacao no comtrolo de bacterias helicobacter
GB9816729D0 (en) * 1998-08-01 1998-09-30 Hoechst Schering Agrevo Gmbh Substituted cyclohexylaminopyrimidines
DE19836697A1 (de) 1998-08-13 2000-02-17 Hoechst Marion Roussel De Gmbh Substituierte 4-Amino-2-aryl-pyrimidine, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
JP2001139561A (ja) * 1999-11-17 2001-05-22 Dainippon Pharmaceut Co Ltd 5−ハロゲノ−6−(4−トリフルオロメチルフェニル)−4−アミノピリミジン誘導体
JP2001247411A (ja) * 2000-03-09 2001-09-11 Tomono Agrica Co Ltd 有害生物防除剤
GB0018951D0 (en) * 2000-08-03 2000-09-20 Smithkline Beecham Plc Novel compounds
CN1473156A (zh) * 2000-11-10 2004-02-04 - 嘧啶衍生物及其作为神经肽y受体配体的用途
US20020137755A1 (en) * 2000-12-04 2002-09-26 Bilodeau Mark T. Tyrosine kinase inhibitors
PL364625A1 (en) * 2001-02-23 2004-12-13 Merck & Co, Inc. N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
DE60204509T2 (de) * 2001-04-20 2006-03-16 Ciba Speciality Chemicals Holding Inc. 4-Amino-2-(2-pyridinyl)pyrimidine als mikrobizide Wirksubstanzen
EP1254903B1 (en) * 2001-04-20 2005-06-08 Ciba SC Holding AG 4-Amino-2-(pyridin-2-yl)pyrimidine as microbicidal active substances
DE10131543A1 (de) * 2001-06-29 2003-01-16 Abbott Lab Pyrimidinoxyalkylpiperazine und ihre therapeutische Verwendung
WO2003026661A1 (fr) * 2001-09-14 2003-04-03 Yamanouchi Pharmaceutical Co., Ltd. Accelerateur de secretion de l'insuline et nouveau derive de pyrimidine
GB0226724D0 (en) * 2002-11-15 2002-12-24 Merck Sharp & Dohme Therapeutic agents
US7423148B2 (en) * 2002-11-21 2008-09-09 Chiron Corporation Small molecule PI 3-kinase inhibitors and methods of their use

Also Published As

Publication number Publication date
US7731985B2 (en) 2010-06-08
EP1484971B1 (en) 2007-07-04
DE60314730D1 (de) 2007-08-16
DE60314730T2 (de) 2008-06-05
US20050143387A1 (en) 2005-06-30
AU2003214110A1 (en) 2003-09-29
JP2005520821A (ja) 2005-07-14
WO2003077656A1 (en) 2003-09-25
EP1484971A1 (en) 2004-12-15
CN1642422A (zh) 2005-07-20
ATE366045T1 (de) 2007-07-15

Similar Documents

Publication Publication Date Title
ES2290436T3 (es) Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies.
ES2242839T3 (es) 4-amino-2- (piridin-2-il)pirimidina como sustancias activas microbicidas.
KR100702814B1 (ko) 살균 활성 물질로서 사용되는 하이드록시스틸벤 화합물 및 이의 제조방법
ES2260202T3 (es) Empleo de derivados de feniletilamina para el tratamiento antimicrobiano de superficies.
TWI329640B (en) Use of substituted 2,4-bis(alkylamino)pyrimidines
ES2215872T3 (es) Nuevos compuestos de diamonio-cuaternario.
JP2005520829A (ja) ベンジルアルコール誘導体
ES2599378T3 (es) Derivados del ácido amino-salicílico antimicrobianos
MXPA02004723A (es) Uso de absorbentes de uv de benzotriazol.
ES2300319T3 (es) Procedimiento para la obtencion de (-)-guaiol y uso de este.
CN100537562C (zh) 作为杀菌活性物质的吡啶基-三嗪衍生物
JP2003226678A (ja) アルコキシベンジルアミン
ES2231564T3 (es) Tetrahidrocarbozoles, un procedimiento para la preparacion de estos compuestos y su empleo.
EP1103180B1 (de) Hydroxyphenylvinylthiazole
JP2006503907A (ja) ビスアルキルベンジルアミン
JP2982873B2 (ja) 1,2−二置換ベンゼンカルボキサミド誘導体及び養毛剤、皮膚外用剤
JP2007526252A (ja) アルコキシフェニルカルボン酸誘導体
KR20060059977A (ko) 3-아릴-2-시아노-3-히드록시-아크릴산 유도체
MXPA01003187A (en) Hydroxystilbene compounds used as microbicidal active substances
MXPA06001069A (en) 3-aryl-2-cyano-3-hydroxy-acrylic acid derivatives
EP1300402A1 (de) Alkoxybenzylamine mit antimikrobiellen Eigenschaften