EE04676B1 - Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine - Google Patents

Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine

Info

Publication number
EE04676B1
EE04676B1 EEP200000626A EEP200000626A EE04676B1 EE 04676 B1 EE04676 B1 EE 04676B1 EE P200000626 A EEP200000626 A EE P200000626A EE P200000626 A EEP200000626 A EE P200000626A EE 04676 B1 EE04676 B1 EE 04676B1
Authority
EE
Estonia
Prior art keywords
imidazopidine
derivatives
preparation
gastric acid
acid secretion
Prior art date
Application number
EEP200000626A
Other languages
English (en)
Estonian (et)
Inventor
Amin Kosrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of EE200000626A publication Critical patent/EE200000626A/xx
Publication of EE04676B1 publication Critical patent/EE04676B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000626A 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine EE04676B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000662 WO1999055705A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (2)

Publication Number Publication Date
EE200000626A EE200000626A (et) 2002-04-15
EE04676B1 true EE04676B1 (et) 2006-08-15

Family

ID=20411154

Family Applications (2)

Application Number Title Priority Date Filing Date
EEP200000626A EE04676B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni, protsess nende valmistamiseks ning nende kasutamine
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Family Applications After (1)

Application Number Title Priority Date Filing Date
EEP200000664A EE04916B1 (et) 1998-04-29 1999-04-23 Imidasopridiini derivaadid, mis inhibeerivad maohappesekretsiooni

Country Status (33)

Country Link
US (2) US6313136B1 (cs)
EP (4) EP1491542B1 (cs)
JP (2) JP3692034B2 (cs)
KR (3) KR100650472B1 (cs)
CN (2) CN1174980C (cs)
AR (2) AR015768A1 (cs)
AT (4) ATE312101T1 (cs)
AU (2) AU769108B2 (cs)
BR (2) BR9909995B1 (cs)
CA (2) CA2329921A1 (cs)
CZ (2) CZ292567B6 (cs)
DE (4) DE69927803T2 (cs)
DK (2) DK1073657T3 (cs)
EE (2) EE04676B1 (cs)
ES (2) ES2252975T3 (cs)
HU (2) HUP0102313A3 (cs)
ID (2) ID27530A (cs)
IL (4) IL139297A0 (cs)
IS (2) IS5683A (cs)
MY (2) MY121389A (cs)
NO (2) NO318203B1 (cs)
NZ (2) NZ507638A (cs)
PL (2) PL343797A1 (cs)
RU (2) RU2238271C2 (cs)
SA (2) SA99200064B1 (cs)
SE (1) SE9801526D0 (cs)
SI (1) SI1073656T1 (cs)
SK (2) SK285768B6 (cs)
TR (4) TR200102612T2 (cs)
TW (2) TWI250159B (cs)
UA (2) UA66846C2 (cs)
WO (2) WO1999055705A1 (cs)
ZA (2) ZA200005796B (cs)

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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
ATE324871T1 (de) * 2001-02-13 2006-06-15 Astrazeneca Ab Neue formulierung mit modifizierter freisetzung
EE05234B1 (et) * 2001-03-08 2009-12-15 Astrazeneca Ab 6-karboksamidoimidaso[1,2-a] pridiinihendite kasutamine ravimi p?hjustatud maohaavandi v„ltimiseks
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
TWI351405B (en) 2002-09-19 2011-11-01 Schering Corp Novel imidazopyridines as cyclin dependent kinase
RS20050377A (en) 2002-11-19 2007-11-15 Altana Pharma Ag., 8-substituted imidazopyridines
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
ES2502490T3 (es) 2003-02-26 2014-10-03 Sugen, Inc. Compuestos aminoheteroarílicos como inhibidores de proteín quinasas
RS52908B (en) 2003-03-10 2014-02-28 Takeda Gmbh NEW PROCEDURE FOR OBTAINING ROFLUMILAST
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20080280944A1 (en) * 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
WO2005070927A2 (en) * 2004-01-26 2005-08-04 Altana Pharma Ag 1,2,4-triazolo[1,5-a] pyridines as gastric acid secretion inhibitors
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
DE602005009257D1 (de) * 2004-12-17 2008-10-02 Pfizer Chroman-derivate als säurepumpenantagonisten
JP5383183B2 (ja) 2005-03-16 2014-01-08 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング ロフルミラストを含有する矯味された剤形
EP1863811B1 (en) * 2005-03-21 2014-03-12 MEI Pharma, Inc. Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
EP1861095A1 (en) * 2005-03-24 2007-12-05 Glaxo Group Limited Derivatives of imidazo(1,2-a)pyridine useful as medicaments for treating gastrointestinal diseases
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
WO2007066187A2 (en) 2005-12-05 2007-06-14 Pfizer Products Inc. Method of treating abnormal cell growth
US8217057B2 (en) 2005-12-05 2012-07-10 Pfizer Inc. Polymorphs of a c-MET/HGFR inhibitor
KR20080108129A (ko) * 2006-03-17 2008-12-11 라퀄리아 파마 인코포레이티드 크로메인 유도체
EP2054036B1 (en) 2006-07-24 2019-12-18 Singh-Broemer and Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
GB2471619B (en) * 2008-03-31 2012-10-31 Council Scient Ind Res Method for the simultaneous preparation of 3-acetoxy-17-acetamdo-16-formyl-androst-5,16-diene and 3-acetoxy-2'-chloro-5-androsteno[17,6-B]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
RU2403904C1 (ru) * 2009-02-26 2010-11-20 Федеральное государственное учреждение "Научно-исследовательский институт по изучению лепры Федерального агентства по здравоохранению и социальному развитию Росздрава" Способ профилактики острых гастродуоденальных язв у больных колоректальным раком в раннем послеоперационном периоде
BRPI1013288A2 (pt) 2009-07-09 2016-03-29 Raqualia Pharma Inc uso de um composto, método de composição farmacêutica para o tratamento de doenças em que a motilidade gastrointestinal anormal está envolvida, kit e embalagem comercial que compreende uma composição farmacêutica contendo o composto
EP3013345B1 (en) * 2013-06-25 2017-11-22 F. Hoffmann-La Roche AG Compounds for treating spinal muscular atrophy
KR102430072B1 (ko) 2013-12-16 2022-08-10 에이비에스 디벨롭먼트 원 인코포레이티드 P2x3 및/또는 p2x2/3 화합물 및 방법
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CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) * 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
MX2020010636A (es) 2018-04-10 2020-10-28 Bayer Ag Proceso para la produccion de acidos 2,6-dialquilfenilaceticos.
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
AU2020377451A1 (en) 2019-11-04 2022-05-26 Cinclus Pharma Holding AB Oral formulation of X842
MX2024005463A (es) 2021-11-05 2024-05-22 Cinclus Pharma Holding Ab Publ Polimorfos de la sal de mesilato de glurato de linaprazan.
AU2022381536A1 (en) 2021-11-05 2024-05-02 Cinclus Pharma Holding AB (publ) Polymorphs of the hydrochloride salt of linaprazan glurate
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
CN120457131A (zh) 2023-01-11 2025-08-08 辛克鲁斯制药控股有限公司 （Publ） 戊二酸利那拉生酯的氢溴酸盐的多晶型物
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GB9107513D0 (en) * 1991-04-10 1991-05-29 Fujisawa Pharmaceutical Co Pyrazolopyridine compound and processes for preparation thereof

Also Published As

Publication number Publication date
EP1073656A1 (en) 2001-02-07
ID26819A (id) 2001-02-15
CZ20003981A3 (cs) 2001-03-14
DE69937076T2 (de) 2008-05-29
SA99200065B1 (ar) 2006-11-07
CN1165535C (zh) 2004-09-08
TWI250159B (en) 2006-03-01
DE69927803D1 (de) 2006-03-02
SA99200065A (ar) 2005-12-03
KR20010043133A (ko) 2001-05-25
HUP0102313A2 (hu) 2001-12-28
CN1307577A (zh) 2001-08-08
ATE312101T1 (de) 2005-12-15
IL139297A0 (en) 2001-11-25
SK14922000A3 (sk) 2001-06-11
EP1073657B1 (en) 2005-12-07
JP3692034B2 (ja) 2005-09-07
NO20005450L (no) 2000-12-22
EE200000626A (et) 2002-04-15
CZ293977B6 (cs) 2004-09-15
JP2002513025A (ja) 2002-05-08
HUP0102425A2 (hu) 2001-11-28
AU4300699A (en) 1999-11-16
KR20050121760A (ko) 2005-12-27
RU2235725C2 (ru) 2004-09-10
BR9909995B1 (pt) 2010-07-13
BR9909996A (pt) 2000-12-26
HK1033317A1 (en) 2001-08-24
JP2002513024A (ja) 2002-05-08
EE200000664A (et) 2002-04-15
EP1491542B1 (en) 2007-09-05
DE69937077T2 (de) 2008-05-29
HK1033457A1 (en) 2001-08-31
ID27530A (id) 2001-04-12
WO1999055706A1 (en) 1999-11-04
EP1491542A3 (en) 2005-01-05
EP1073656B1 (en) 2005-10-19
UA66846C2 (uk) 2004-06-15
CA2329921A1 (en) 1999-11-04
ES2252975T3 (es) 2006-05-16
NZ507638A (en) 2003-10-31
IS5683A (is) 2000-10-25
DE69937077D1 (de) 2007-10-18
RU2238271C2 (ru) 2004-10-20
KR100650472B1 (ko) 2006-11-28
NZ507639A (en) 2004-01-30
TR200102728T2 (tr) 2002-06-21
HUP0102313A3 (en) 2002-10-28
NO318203B1 (no) 2005-02-14
JP3883383B2 (ja) 2007-02-21
NO20005450D0 (no) 2000-10-27
US6313137B1 (en) 2001-11-06
EP1491543B1 (en) 2007-09-05
IL139297A (en) 2007-06-03
SK285768B6 (sk) 2007-07-06
AU769190B2 (en) 2004-01-22
CZ292567B6 (cs) 2003-10-15
SK14912000A3 (sk) 2001-06-11
CA2329922A1 (en) 1999-11-04
EP1491543A1 (en) 2004-12-29
KR20010043134A (ko) 2001-05-25
CN1174980C (zh) 2004-11-10
UA67769C2 (uk) 2004-07-15
HK1071139A1 (en) 2005-07-08
WO1999055705A1 (en) 1999-11-04
HK1036981A1 (en) 2002-01-25
DE69937076D1 (de) 2007-10-18
DE69927803T2 (de) 2006-07-06
KR100595805B1 (ko) 2006-07-03
SI1073656T1 (sl) 2006-02-28
BR9909995A (pt) 2000-12-26
HK1036984A1 (en) 2002-01-25
SE9801526D0 (sv) 1998-04-29
MY121389A (en) 2006-01-28
CA2329922C (en) 2006-04-11
CZ20003982A3 (cs) 2001-02-14
DE69928792D1 (de) 2006-01-12
DE69928792T2 (de) 2006-07-20
ATE372340T1 (de) 2007-09-15
DK1073656T3 (da) 2006-01-16
EP1073657A1 (en) 2001-02-07
EP1491542A2 (en) 2004-12-29
NO20005451L (no) 2000-12-27
MY121379A (en) 2006-01-28
PL343801A1 (en) 2001-09-10
AU4300799A (en) 1999-11-16
DK1073657T3 (da) 2006-03-13
IS5684A (is) 2000-10-25
PL195000B1 (pl) 2007-07-31
CN1306533A (zh) 2001-08-01
IL139200A (en) 2010-04-29
TR200003176T2 (tr) 2001-03-21
TR200102612T2 (tr) 2002-06-21
AR015768A1 (es) 2001-05-16
SA99200064B1 (ar) 2006-10-11
TR200003149T2 (tr) 2001-03-21
EE04916B1 (et) 2007-10-15
NO20005451D0 (no) 2000-10-27
PL343797A1 (en) 2001-09-10
HUP0102425A3 (en) 2002-12-28
NO317262B1 (no) 2004-09-27
KR100595806B1 (ko) 2006-07-03
ATE372339T1 (de) 2007-09-15
ZA200005797B (en) 2002-01-18
BR9909996B1 (pt) 2010-08-24
ES2249913T3 (es) 2006-04-01
US6313136B1 (en) 2001-11-06
WO1999055706A9 (en) 2000-03-16
ZA200005796B (en) 2002-01-18
AU769108B2 (en) 2004-01-15
TW490466B (en) 2002-06-11
ATE307130T1 (de) 2005-11-15
AR015769A1 (es) 2001-05-16
IL139200A0 (en) 2001-11-25

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