DK3334824T3 - Pd-1-antistoffer - Google Patents

Pd-1-antistoffer Download PDF

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Publication number
DK3334824T3
DK3334824T3 DK16834640.1T DK16834640T DK3334824T3 DK 3334824 T3 DK3334824 T3 DK 3334824T3 DK 16834640 T DK16834640 T DK 16834640T DK 3334824 T3 DK3334824 T3 DK 3334824T3
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antibodies
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DK16834640.1T
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Hemanta Baruah
Cheng Chen
Xiaolin Liu
Andy Tsun
Dechao M Yu
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Innovent Biologics Suzhou Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
DK16834640.1T 2015-08-10 2016-08-09 Pd-1-antistoffer DK3334824T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CN2015/086494 WO2017024465A1 (en) 2015-08-10 2015-08-10 Pd-1 antibodies
PCT/CN2016/094122 WO2017025016A1 (en) 2015-08-10 2016-08-09 Pd-1 antibodies

Publications (1)

Publication Number Publication Date
DK3334824T3 true DK3334824T3 (da) 2022-02-07

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK16834640.1T DK3334824T3 (da) 2015-08-10 2016-08-09 Pd-1-antistoffer

Country Status (27)

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US (1) US10316089B2 (da)
EP (1) EP3334824B1 (da)
JP (1) JP6513296B2 (da)
KR (1) KR102132100B1 (da)
CN (2) CN110003339B (da)
AR (1) AR105489A1 (da)
AU (1) AU2016307002B2 (da)
BR (1) BR112018002274B1 (da)
CA (1) CA2990492C (da)
CY (1) CY1124955T1 (da)
DK (1) DK3334824T3 (da)
ES (1) ES2904586T3 (da)
HK (1) HK1255195B (da)
HR (1) HRP20220111T1 (da)
HU (1) HUE058273T2 (da)
IL (1) IL256844B (da)
LT (1) LT3334824T (da)
MX (1) MX365390B (da)
MY (1) MY199019A (da)
NZ (1) NZ738979A (da)
PL (1) PL3334824T3 (da)
PT (1) PT3334824T (da)
RS (1) RS62897B1 (da)
RU (1) RU2686612C1 (da)
SI (1) SI3334824T1 (da)
TW (1) TWI674275B (da)
WO (2) WO2017024465A1 (da)

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MX2018001671A (es) 2018-09-26
IL256844B (en) 2022-08-01
ES2904586T3 (es) 2022-04-05
CA2990492C (en) 2021-11-23
CN110003339A (zh) 2019-07-12
CN110003339B (zh) 2022-06-28
RS62897B1 (sr) 2022-03-31
US10316089B2 (en) 2019-06-11
MX365390B (es) 2019-05-31
CN108473977A (zh) 2018-08-31
PT3334824T (pt) 2022-02-08
EP3334824A4 (en) 2019-01-23
KR20180030580A (ko) 2018-03-23
PL3334824T3 (pl) 2022-03-28
KR102132100B1 (ko) 2020-07-08
AR105489A1 (es) 2017-10-11
EP3334824B1 (en) 2021-11-17
CY1124955T1 (el) 2023-01-05
CN108473977B (zh) 2019-03-26
US20170044260A1 (en) 2017-02-16
BR112018002274A2 (pt) 2018-12-11
AU2016307002A1 (en) 2018-02-01
HUE058273T2 (hu) 2022-07-28
AU2016307002B2 (en) 2019-07-11
LT3334824T (lt) 2022-02-25
JP2018531986A (ja) 2018-11-01
BR112018002274B1 (pt) 2021-12-07
JP6513296B2 (ja) 2019-05-15
RU2686612C1 (ru) 2019-04-29
EP3334824A1 (en) 2018-06-20
WO2017025016A1 (en) 2017-02-16
HK1255195B (zh) 2020-04-09
SI3334824T1 (sl) 2022-04-29
WO2017024465A1 (en) 2017-02-16
IL256844A (en) 2018-03-29
CA2990492A1 (en) 2017-02-16
TW201713698A (en) 2017-04-16

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