JPS6051189B2
(ja)
*
|
1980-07-21 |
1985-11-12 |
株式会社日立製作所 |
磁気バブル駆動回路
|
JPS60226873A
(ja)
*
|
1984-03-28 |
1985-11-12 |
Sankyo Co Ltd |
1,3−ベンゾオキサチオ−ル誘導体及びその製法
|
CN1003445B
(zh)
*
|
1984-10-03 |
1989-03-01 |
武田药品工业株式会社 |
噻唑烷二酮衍生物,其制备方法和用途
|
DK173350B1
(da)
|
1985-02-26 |
2000-08-07 |
Sankyo Co |
Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
|
JPH0653738B2
(ja)
*
|
1985-02-26 |
1994-07-20 |
三共株式会社 |
チアゾリジン誘導体
|
HU210339B
(en)
*
|
1985-05-21 |
1995-03-28 |
Pfizer |
Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect
|
US4738972A
(en)
*
|
1985-05-21 |
1988-04-19 |
Pfizer Inc. |
Hypoglycemic thiazolidinediones
|
JPH06779B2
(ja)
*
|
1985-06-10 |
1994-01-05 |
武田薬品工業株式会社 |
チアゾリジオン誘導体およびそれを含んでなる医薬組成物
|
JPS62234085A
(ja)
*
|
1985-12-18 |
1987-10-14 |
Sankyo Co Ltd |
チアゾリジン誘導体を有効成分とする糖尿病性合併症治療剤
|
US4873255A
(en)
*
|
1987-02-04 |
1989-10-10 |
Sankyo Company Limited |
Thiazolidinone derivatives, their preparation and their use
|
JP2574845B2
(ja)
*
|
1987-02-04 |
1997-01-22 |
三共株式会社 |
チアゾリジン化合物
|
US4791125A
(en)
*
|
1987-12-02 |
1988-12-13 |
Pfizer Inc. |
Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
|
US4798835A
(en)
*
|
1987-12-02 |
1989-01-17 |
Pfizer Inc. |
dl-5-[(2-benzyl-3,4-dihydro-2H-benzopyran-6-yl)methyl]thiazolidine-2,4-dione as an anti-atherosclerosis agent
|
US5132310A
(en)
*
|
1988-08-09 |
1992-07-21 |
Hoffmann-La Roche Inc. |
Pharmacologically active chromanes
|
US5015661A
(en)
*
|
1988-08-09 |
1991-05-14 |
Hoffmann-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
US5260294A
(en)
*
|
1988-08-09 |
1993-11-09 |
Hoffman-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
GB8919417D0
(en)
|
1989-08-25 |
1989-10-11 |
Beecham Group Plc |
Novel compounds
|
US5053420A
(en)
*
|
1989-10-13 |
1991-10-01 |
Pershadsingh Harrihar A |
Thiazolidine derivatives for the treatment of hypertension
|
JP2826379B2
(ja)
*
|
1990-01-22 |
1998-11-18 |
三共株式会社 |
チアゾリジン誘導体を有効成分とする肥満性高血圧症治療剤
|
US5143930A
(en)
*
|
1990-02-07 |
1992-09-01 |
Sankyo Company, Limited |
Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
|
DE69100282T3
(de)
*
|
1990-02-09 |
2001-01-11 |
Pharmacia & Upjohn Co., Kalamazoo |
Verwendung insulin-sensiblisierender wirkstoffe zur behandlung von hypertonie.
|
US5356913A
(en)
*
|
1990-02-09 |
1994-10-18 |
The Upjohn Company |
Use of insulin sensitizing agents to treat hypertension
|
EP0839812A1
(de)
*
|
1990-04-27 |
1998-05-06 |
Sankyo Company Limited |
Herstellung von Benzylthiazolidinederivaten
|
GB9023584D0
(en)
*
|
1990-10-30 |
1990-12-12 |
Beecham Group Plc |
Novel compounds
|
CA2082003A1
(en)
*
|
1991-11-20 |
1993-05-21 |
David Laffan |
Process for the preparation of substituted pentaalkylchromenes
|
DE69222182T2
(de)
*
|
1991-12-18 |
1998-02-26 |
Warner Lambert Co |
Verfahren für die herstellung einer festen dispersion
|
NO302471B1
(no)
*
|
1991-12-26 |
1998-03-09 |
Sankyo Co |
Tiazolidinforbindelser og farmasöytisk preparat
|
NO302519B1
(no)
*
|
1991-12-26 |
1998-03-16 |
Sankyo Co |
Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
|
CA2089012A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2,5,7,8-tetra- alkyl-2-(4-aminophenoxymethyl) chromans
|
CA2089013A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2, 5, 7, 8- tetraalkyl-2-(4-aminophenoxymethyl) chromans
|
EP0590793B1
(de)
|
1992-08-31 |
1999-10-13 |
Sankyo Company Limited |
Oxazolidin-Derivate mit Antidiabetika und Anti-Fettleibigkeit-Eigenschaften, ihre Herstellung und therapeutische Verwendung
|
JPH0631079U
(ja)
*
|
1992-09-22 |
1994-04-22 |
沖電線株式会社 |
シート付き小型smtコネクタ
|
US5594016A
(en)
*
|
1992-12-28 |
1997-01-14 |
Mitsubishi Chemical Corporation |
Naphthalene derivatives
|
AU6114794A
(en)
*
|
1993-02-24 |
1994-09-14 |
Sankyo Company Limited |
Arteriosclerosis remedy
|
USRE39384E1
(en)
|
1993-09-01 |
2006-11-07 |
Smithkline Beecham P.L.C. |
Substituted thiazolidinedione derivatives
|
US5478852C1
(en)
*
|
1993-09-15 |
2001-03-13 |
Sankyo Co |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
|
AU749416B2
(en)
*
|
1993-09-15 |
2002-06-27 |
Daiichi Sankyo Company, Limited |
Use of thiazolidinediones to prevent or delay onset of NIDDM
|
US6046222A
(en)
*
|
1993-09-15 |
2000-04-04 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
US5874454A
(en)
*
|
1993-09-15 |
1999-02-23 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
RU2195282C2
(ru)
*
|
1993-09-15 |
2002-12-27 |
Санкио Компани Лимитед |
Применение тиазолидиндионов для предотвращения или отдаления наступления инсулиннезависимого сахарного диабета (niddm)
|
WO1995018125A1
(fr)
*
|
1993-12-27 |
1995-07-06 |
Japan Tobacco Inc. |
Derive d'isoxazolidinedione et son utilisation
|
CA2146701A1
(en)
*
|
1994-04-11 |
1995-10-12 |
Takashi Fujita |
Heterocyclic compounds having anti-diabetic activity, their preparation and their use
|
US5594015A
(en)
*
|
1994-06-22 |
1997-01-14 |
Regents Of The University Of California |
Thiazolidine derivatives for the treatment of psoriasis
|
CZ261095A3
(en)
*
|
1994-10-07 |
1996-04-17 |
Sankyo Co |
Oxime derivatives, process of their preparation, pharmaceutical composition containing thereof and their use
|
US5708012A
(en)
*
|
1995-04-28 |
1998-01-13 |
Sankyo Company, Limited |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus
|
CZ293016B6
(cs)
*
|
1995-06-01 |
2004-01-14 |
Sankyo Company Limited |
Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem
|
RU2158607C2
(ru)
*
|
1995-07-03 |
2000-11-10 |
Санкио Компани Лимитед |
Лечение артериосклероза и ксантомы
|
KR19990036290A
(ko)
*
|
1995-08-10 |
1999-05-25 |
로즈 암스트롱 |
비인슐린 의존성 진성 당뇨병 환자에 대한 외인성 인슐린 투여량의 감소 방법
|
WO1997018811A1
(en)
*
|
1995-11-17 |
1997-05-29 |
Warner-Lambert Company |
A method of treating myotonic dystrophy
|
EP0783888A1
(de)
*
|
1995-12-26 |
1997-07-16 |
Sankyo Company Limited |
Verwendung von Troglitazone und verwandten Thiazolidinedionen zur Herstellung eines Medikaments für die Behandlung und Vorbeugung der Osteoporose
|
IN182496B
(de)
*
|
1996-02-20 |
1999-04-17 |
Reddy Research Foundation |
|
IL120443A
(en)
*
|
1996-03-18 |
2000-07-16 |
Sankyo Co |
Use of an insulin sensitizer for the manufacture of a medicament for the treatment or prophylaxis of pancreatitis
|
CZ318098A3
(cs)
*
|
1996-04-04 |
1999-01-13 |
Sankyo Company, Limited |
Deriváty fenylalkylkarboxylové kyseliny, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje
|
EP0801063B1
(de)
*
|
1996-04-09 |
2003-01-15 |
Dr. Reddy's Laboratories Ltd. |
Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven Eigenschaften, Verfahren zu deren Herstellung und pharmazeutischen Zusammenstellungen, die sie enthalten
|
ZA973850B
(en)
*
|
1996-05-06 |
1997-12-02 |
Reddy Research Foundation |
Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
|
US5889032A
(en)
*
|
1996-05-06 |
1999-03-30 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
US5801173A
(en)
*
|
1996-05-06 |
1998-09-01 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
US5919782A
(en)
*
|
1996-05-06 |
1999-07-06 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
DE19619819A1
(de)
*
|
1996-05-16 |
1997-11-20 |
Boehringer Mannheim Gmbh |
Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltenden Arzneimittel
|
WO1997043283A1
(de)
*
|
1996-05-16 |
1997-11-20 |
Boehringer Mannheim Gmbh |
Neues verfahren zur herstellung von troglitazone
|
CA2257284C
(en)
*
|
1996-05-31 |
2005-10-04 |
Sankyo Company Limited |
Remedy for autoimmune diseases
|
GB9611947D0
(en)
*
|
1996-06-07 |
1996-08-07 |
Glaxo Group Ltd |
Medicaments
|
EP0844997A1
(de)
*
|
1996-06-19 |
1998-06-03 |
Dr. Reddy's Research Foundation |
Neue polymorphe formen des troglitazons die eine erhöhte anti-diabetische wirkung besitzen und verfahren zu ihrer herstellung
|
USRE39266E1
(en)
*
|
1996-07-01 |
2006-09-05 |
Dr. Reddy's Laboratories, Limited |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
US6114526A
(en)
|
1996-07-01 |
2000-09-05 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
KR100579765B1
(ko)
*
|
1996-07-01 |
2006-12-28 |
닥터 레디스 레보러터리즈 리미티드 |
신규헤테로고리형화합물의제조방법,이를함유하는약제조성물및당뇨병및이와관련된질병의치료에있어서그의용도
|
US6372750B2
(en)
|
1996-07-01 |
2002-04-16 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
|
US5885997A
(en)
*
|
1996-07-01 |
1999-03-23 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
JP2000514807A
(ja)
*
|
1996-07-12 |
2000-11-07 |
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー |
レプチン耐性の新規な治療
|
HUP0002941A3
(en)
*
|
1996-09-12 |
2001-11-28 |
Sankyo Company Ltd Chuo Ku |
Glutathione reductase activity potentiator containing troglitazone
|
EP0974348B1
(de)
*
|
1996-11-08 |
2008-07-02 |
Nippon Chemiphar Co., Ltd. |
Mittel zur verringerung der eigeweidefette
|
WO1998039967A1
(en)
*
|
1997-03-12 |
1998-09-17 |
The General Hospital Corporation |
A method for treating or preventing alzheimer's disease
|
US6011036A
(en)
*
|
1997-04-15 |
2000-01-04 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them
|
US6011031A
(en)
*
|
1997-05-30 |
2000-01-04 |
Dr. Reddy's Research Foundation |
Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
|
SE9702305D0
(sv)
*
|
1997-06-17 |
1997-06-17 |
Astra Ab |
New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
|
IL133142A0
(en)
*
|
1997-06-18 |
2001-03-19 |
Smithkline Beecham Plc |
Treatment of diabetes with thiazolidinedione and metformin
|
EP1671637A3
(de)
*
|
1997-06-18 |
2007-12-19 |
SmithKline Beecham P.L.C. |
Behandlung der Diabetes mit Thiazolidindione und Sulphonylurea
|
GB9715295D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
GB9715306D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
US6171856B1
(en)
|
1997-07-30 |
2001-01-09 |
Board Of Regents, The University Of Texas System |
Methods and compositions relating to no-mediated cytotoxicity
|
FR2766820B1
(fr)
*
|
1997-07-31 |
1999-10-22 |
Rhodia Chimie Sa |
Procede de preparation de 2h-1-benzopyranes et intermediaires de synthese utiles dans la mise en oeuvre du procede
|
KR20010030881A
(ko)
*
|
1997-10-02 |
2001-04-16 |
가와무라 요시부미 |
아미도카르복실산 유도체
|
EP0916665A1
(de)
*
|
1997-11-11 |
1999-05-19 |
Lonza A.G. |
Verfahren zur Herstellung von Chromanderivaten
|
KR100567183B1
(ko)
*
|
1997-11-14 |
2006-06-13 |
론자 아게 |
포르밀이미다졸의제조방법
|
HUP9902721A2
(hu)
|
1997-11-25 |
1999-12-28 |
The Procter & Gamble Co. |
Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
|
AU1507799A
(en)
*
|
1997-12-16 |
1999-07-05 |
Sankyo Company Limited |
Leukemia remedy
|
US20040058873A1
(en)
*
|
1998-03-12 |
2004-03-25 |
Esmond Robert W. |
Method for treating or preventing Alzheimer's disease
|
ID26082A
(id)
|
1998-03-19 |
2000-11-23 |
Briston Myers Squib Company |
Sistem pengiriman lepas terkendali dwifasa untuk zat-zat farmasi kelarutan tinggi dan metodenya
|
WO2000007582A2
(en)
*
|
1998-08-06 |
2000-02-17 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives for the treatment or prevention of cataracts
|
WO2000010994A1
(en)
*
|
1998-08-19 |
2000-03-02 |
Sankyo Company, Limited |
Process for the preparation of 2-(aryloxymethyl)-2,5,7,8-tetramethylchroman-6-ols
|
CN1319012A
(zh)
|
1998-09-17 |
2001-10-24 |
布里斯托尔-迈尔斯斯奎布公司 |
用aP2抑制剂及其联合形式治疗糖尿病的方法
|
US6028088A
(en)
*
|
1998-10-30 |
2000-02-22 |
The University Of Mississippi |
Flavonoid derivatives
|
AR023699A1
(es)
|
1998-11-12 |
2002-09-04 |
Smithkline Beecham Corp |
Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica
|
GB9824893D0
(en)
*
|
1998-11-12 |
1999-01-06 |
Smithkline Beckman Corp |
Novel method of treatment
|
WO2000028989A1
(en)
|
1998-11-12 |
2000-05-25 |
Smithkline Beecham P.L.C. |
Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
|
CA2350599A1
(en)
*
|
1998-11-20 |
2000-06-02 |
Genentech, Inc. |
Method of inhibiting angiogenesis
|
US6191154B1
(en)
|
1998-11-27 |
2001-02-20 |
Case Western Reserve University |
Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
|
US5968960A
(en)
*
|
1999-01-14 |
1999-10-19 |
The Regents Of The University Of California |
Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism
|
US6127394A
(en)
*
|
1999-03-08 |
2000-10-03 |
The University Of Mississippi |
1,2-Dithiolane derivatives
|
US6204288B1
(en)
|
1999-03-08 |
2001-03-20 |
The University Of Mississippi |
1,2-dithiolane derivatives
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
US7041691B1
(en)
*
|
1999-06-30 |
2006-05-09 |
Amgen Inc. |
Compounds for the modulation of PPARγ activity
|
JP2001072592A
(ja)
|
1999-07-01 |
2001-03-21 |
Kyowa Hakko Kogyo Co Ltd |
テロメラーゼ阻害剤
|
AR028299A1
(es)
|
1999-09-17 |
2003-05-07 |
Novartis Ag |
Una composicion farmaceutica que comprende nateglinida, un proceso para su preparacion y el uso de dicha composicion para la preparacion de un medicamento para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con diabetes.
|
US6878749B2
(en)
|
1999-09-17 |
2005-04-12 |
Novartis Ag |
Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
|
US6559188B1
(en)
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
US6586438B2
(en)
|
1999-11-03 |
2003-07-01 |
Bristol-Myers Squibb Co. |
Antidiabetic formulation and method
|
KR100716525B1
(ko)
|
1999-12-03 |
2007-05-10 |
교토 야쿠힝 고교 가부시키가이샤 |
신규한 헤테로시클릭 화합물과 이의 염 및 이들의 의약 용도
|
DK1741445T3
(da)
|
2000-01-21 |
2013-11-04 |
Novartis Ag |
Kombinationer omfattende dipeptidylpeptidase-IV-inhibitorer og antidiabetiske midler
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
US6680387B2
(en)
*
|
2000-04-24 |
2004-01-20 |
Aryx Therapeutics |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
US6958355B2
(en)
*
|
2000-04-24 |
2005-10-25 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
WO2001082916A2
(en)
*
|
2000-05-03 |
2001-11-08 |
Tularik Inc. |
Combination therapeutic compositions and methods of use
|
GB0014969D0
(en)
|
2000-06-19 |
2000-08-09 |
Smithkline Beecham Plc |
Novel method of treatment
|
US20030171399A1
(en)
*
|
2000-06-28 |
2003-09-11 |
Tularik Inc. |
Quinolinyl and benzothiazolyl modulators
|
MXPA03001157A
(es)
*
|
2000-08-07 |
2004-02-17 |
Ranbaxy Signature Llc |
Formulacion liquida de metformina.
|
AU2001294673A1
(en)
|
2000-09-21 |
2002-04-02 |
Aryx Therapeutics |
Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, andatherosclerosis
|
FR2816840B1
(fr)
*
|
2000-11-17 |
2004-04-09 |
Flamel Tech Sa |
Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
|
US6452014B1
(en)
|
2000-12-22 |
2002-09-17 |
Geron Corporation |
Telomerase inhibitors and methods of their use
|
US6774112B2
(en)
|
2001-04-11 |
2004-08-10 |
Bristol-Myers Squibb Company |
Amino acid complexes of C-aryl glucosides for treatment of diabetes and method
|
US20060047000A1
(en)
*
|
2001-04-24 |
2006-03-02 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
WO2002096880A1
(fr)
*
|
2001-05-29 |
2002-12-05 |
Kyoto Pharmaceutical Industries, Ltd. |
Nouveau compose heterocyclique et son utilisation medicinale
|
KR100874677B1
(ko)
*
|
2001-05-29 |
2008-12-18 |
교토 야쿠힝 고교 가부시키가이샤 |
신규 복소환 유도체 및 그 의약 용도
|
JP4152641B2
(ja)
*
|
2001-08-07 |
2008-09-17 |
クラシエ製薬株式会社 |
チアゾリジン誘導体の副作用軽減剤
|
US8101209B2
(en)
*
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
FR2830447B1
(fr)
*
|
2001-10-09 |
2004-04-16 |
Flamel Tech Sa |
Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
AU2002348276A1
(en)
*
|
2001-11-16 |
2003-06-10 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
US7015345B2
(en)
*
|
2002-02-21 |
2006-03-21 |
Asahi Kasei Pharma Corporation |
Propionic acid derivatives
|
IL163666A0
(en)
|
2002-02-22 |
2005-12-18 |
New River Pharmaceuticals Inc |
Active agent delivery systems and methods for protecting and administering active agents
|
ES2314227T7
(es)
*
|
2002-04-09 |
2012-11-19 |
Flamel Technologies |
Formulacion farmaceutica oral en forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxilicina.
|
EP1492511B3
(de)
|
2002-04-09 |
2012-05-02 |
Flamel Technologies |
Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
|
EP1504525A2
(de)
*
|
2002-05-14 |
2005-02-09 |
Siemens Aktiengesellschaft |
Verfahren zum erzeugen eines sendesignals
|
US8268352B2
(en)
*
|
2002-08-05 |
2012-09-18 |
Torrent Pharmaceuticals Limited |
Modified release composition for highly soluble drugs
|
US8216609B2
(en)
*
|
2002-08-05 |
2012-07-10 |
Torrent Pharmaceuticals Limited |
Modified release composition of highly soluble drugs
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
US20040176425A1
(en)
*
|
2003-01-24 |
2004-09-09 |
Washburn William N. |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
US8017762B2
(en)
*
|
2003-04-17 |
2011-09-13 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
EP1620544B1
(de)
*
|
2003-04-17 |
2018-09-19 |
Alnylam Pharmaceuticals Inc. |
Modifizierte irna-agentien
|
US7851615B2
(en)
*
|
2003-04-17 |
2010-12-14 |
Alnylam Pharmaceuticals, Inc. |
Lipophilic conjugated iRNA agents
|
US7723509B2
(en)
|
2003-04-17 |
2010-05-25 |
Alnylam Pharmaceuticals |
IRNA agents with biocleavable tethers
|
US8796436B2
(en)
|
2003-04-17 |
2014-08-05 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
US20050004179A1
(en)
*
|
2003-05-22 |
2005-01-06 |
Pedersen Ward A. |
Methods and materials for treating, detecting, and reducing the risk of developing Alzheimer's Disease
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
US7371759B2
(en)
*
|
2003-09-25 |
2008-05-13 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7223761B2
(en)
|
2003-10-03 |
2007-05-29 |
Amgen Inc. |
Salts and polymorphs of a potent antidiabetic compound
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
AR046778A1
(es)
|
2003-11-12 |
2005-12-21 |
Phenomix Corp |
Compuestos heterociclicos de acido boronico. metodos de obtencion y composiciones farmaceuticas.
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7420059B2
(en)
*
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
CA2573848A1
(en)
*
|
2004-07-12 |
2006-02-16 |
Phenomix Corporation |
Constrained cyano compounds
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
CN101119748A
(zh)
*
|
2004-12-13 |
2008-02-06 |
第一三共株式会社 |
用于治疗糖尿病的药物组合物
|
US7317024B2
(en)
|
2005-01-13 |
2008-01-08 |
Bristol-Myers Squibb Co. |
Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
WO2006086464A2
(en)
*
|
2005-02-10 |
2006-08-17 |
Bristol-Myers Squibb Company |
Dihydroquinazolinones as 5ht modulators
|
US20070269486A1
(en)
*
|
2005-03-14 |
2007-11-22 |
Conor Medsystems, Llc. |
Methods and Devices for Reducing Tissue Damage After Ischemic Injury
|
US20080319031A1
(en)
*
|
2005-03-18 |
2008-12-25 |
Orchid Chemicals & Pharmaceuticals Limited |
Novel Tyrosine Derivatives
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7888381B2
(en)
|
2005-06-14 |
2011-02-15 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
|
MX2008000811A
(es)
*
|
2005-07-28 |
2008-03-18 |
Squibb Bristol Myers Co |
Tetrahidro-1h-pitido[4,3-b]indoles substituidos como agonistas y antagonistas del receptor de serotonina.
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
US20080064884A1
(en)
*
|
2006-05-10 |
2008-03-13 |
Astrazeneca Ab |
Novel Process 1
|
EP2099767A1
(de)
|
2006-11-01 |
2009-09-16 |
Brystol-Myers Squibb Company |
Modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-b-aktivität und deren verwendung
|
EP2089355A2
(de)
|
2006-11-01 |
2009-08-19 |
Brystol-Myers Squibb Company |
Modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-kappa-b-aktivität und deren verwendung
|
US7994190B2
(en)
|
2006-11-01 |
2011-08-09 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
BRPI0809583B1
(pt)
|
2007-03-30 |
2022-02-22 |
Ambrx, Inc |
Polipeptídeo fgf-21 modificado, composição compreendendo o mesmo, método para produzir o referido polipetídeo fgf-21 e célula compreendendo um polinucleotídeo
|
US11241420B2
(en)
|
2007-04-11 |
2022-02-08 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
EP2141989B1
(de)
|
2007-04-11 |
2013-09-11 |
Omeros Corporation |
Zusammensetzungen und verfahren zur vorbeugung und behandlung von suchtkrankheiten
|
US20160331729A9
(en)
*
|
2007-04-11 |
2016-11-17 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
MX354786B
(es)
|
2007-06-04 |
2018-03-21 |
Synergy Pharmaceuticals Inc |
Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
JP2011503081A
(ja)
|
2007-11-01 |
2011-01-27 |
ブリストル−マイヤーズ スクイブ カンパニー |
グルココルチコイド受容体、AP−1および/またはNF−κB活性の調節剤として有用な非ステロイド性化合物、並びにその使用
|
JP2011522828A
(ja)
|
2008-06-04 |
2011-08-04 |
シナジー ファーマシューティカルズ インコーポレイテッド |
胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
EP3241839B1
(de)
|
2008-07-16 |
2019-09-04 |
Bausch Health Ireland Limited |
Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
|
EP2376515A1
(de)
|
2008-12-23 |
2011-10-19 |
Pharmasset, Inc. |
Synthese von purinnukleosiden
|
SG172361A1
(en)
*
|
2008-12-23 |
2011-07-28 |
Pharmasset Inc |
Nucleoside analogs
|
AR074897A1
(es)
|
2008-12-23 |
2011-02-23 |
Pharmasset Inc |
Fosforamidatos de nucleosidos
|
EP3398599A1
(de)
|
2009-03-11 |
2018-11-07 |
Omeros Corporation |
Zusammensetzungen und verfahren zur vorbeugung und behandlung von suchtkrankheiten
|
US10429384B2
(en)
|
2010-01-22 |
2019-10-01 |
Dana-Farber Cancer Institute, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of metabolic disorders
|
PT3290428T
(pt)
|
2010-03-31 |
2021-12-27 |
Gilead Pharmasset Llc |
Comprimido compreendendo 2-(((s)-(((2r,3r,4r,5r)-5-(2,4-dioxo-3,4-dihidropirimidin-1-(2h)-il)¿4¿fluoro¿3¿hidroxi¿4¿metiltetrahidrofuran¿2¿il)metoxi) (fenoxi)fosforil)amino)propanoato de (s)- isopropil cristalino
|
BR112013000626B1
(pt)
|
2010-07-09 |
2019-11-26 |
Bhv Pharma Inc |
formulação farmacêutica e método para preparar uma forma de dosagem da mesma
|
US20130156720A1
(en)
|
2010-08-27 |
2013-06-20 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
US20120094959A1
(en)
|
2010-10-19 |
2012-04-19 |
Bonnie Blazer-Yost |
Treatment of cystic diseases
|
US9486433B2
(en)
|
2012-10-12 |
2016-11-08 |
Mochida Pharmaceuticals Co. Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
DK2914250T3
(en)
|
2012-11-05 |
2018-06-18 |
Commissariat Energie Atomique |
COMBINATION OF ANTICANCER SUCH AS A TYROSINKINASE INHIBITOR AND A STAT5 ANTAGONIST, PRIOR TO A THIAZOLIDE INDION FOR ELIMINATING HEMATOLOGICAL CANCER STAM CELLS IN VIVO AND FOR THE PREVENTION OF RECIDIVISM OF RECIDIVES
|
EP2968245B1
(de)
|
2013-03-15 |
2021-05-05 |
Mochida Pharmaceutical Co., Ltd. |
Zusammensetzungen und verfahren zur behandlung nichtalkoholischer steatohepatitis
|
US10441560B2
(en)
|
2013-03-15 |
2019-10-15 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
WO2014151206A1
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
US9486494B2
(en)
|
2013-03-15 |
2016-11-08 |
Synergy Pharmaceuticals, Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
EA201592263A1
(ru)
|
2013-06-05 |
2016-05-31 |
Синерджи Фармасьютикалз, Инк. |
Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
US20160235807A1
(en)
|
2013-10-09 |
2016-08-18 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines
|
WO2016065326A2
(en)
|
2014-10-24 |
2016-04-28 |
Bristol-Myers Squibb Company |
Modified fgf-21 polypeptides and uses thereof
|
US10034868B2
(en)
|
2014-11-04 |
2018-07-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
|
MX2021000601A
(es)
|
2018-07-19 |
2021-04-13 |
Astrazeneca Ab |
Metodos de tratamiento de hfpef empleando dapagliflozina y composiciones que comprenden la misma.
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
WO2023144722A1
(en)
|
2022-01-26 |
2023-08-03 |
Astrazeneca Ab |
Dapagliflozin for use in the treatment of prediabetes or reducing the risk of developing type 2 diabetes
|