DE69222182T2 - Verfahren für die herstellung einer festen dispersion - Google Patents

Verfahren für die herstellung einer festen dispersion

Info

Publication number
DE69222182T2
DE69222182T2 DE1992622182 DE69222182T DE69222182T2 DE 69222182 T2 DE69222182 T2 DE 69222182T2 DE 1992622182 DE1992622182 DE 1992622182 DE 69222182 T DE69222182 T DE 69222182T DE 69222182 T2 DE69222182 T2 DE 69222182T2
Authority
DE
Germany
Prior art keywords
producing
method
solid dispersion
dispersion
solid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1992622182
Other languages
English (en)
Other versions
DE69222182D1 (de
Inventor
Isaac Ghebre-Sellassie
Robert Reisch
Riten Parikh
Mahdi Fawzi
Russell Nesbitt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US80965691A priority Critical
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Priority to PCT/US1992/009989 priority patent/WO1993011749A1/en
Application granted granted Critical
Publication of DE69222182T2 publication Critical patent/DE69222182T2/de
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
DE1992622182 1991-12-18 1992-11-18 Verfahren für die herstellung einer festen dispersion Expired - Lifetime DE69222182T2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US80965691A true 1991-12-18 1991-12-18
PCT/US1992/009989 WO1993011749A1 (en) 1991-12-18 1992-11-18 A process for the preparation of a solid dispersion

Publications (1)

Publication Number Publication Date
DE69222182T2 true DE69222182T2 (de) 1998-02-26

Family

ID=25201894

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1992622182 Expired - Fee Related DE69222182D1 (de) 1991-12-18 1992-11-18 Verfahren für die herstellung einer festen dispersion
DE1992622182 Expired - Lifetime DE69222182T2 (de) 1991-12-18 1992-11-18 Verfahren für die herstellung einer festen dispersion

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1992622182 Expired - Fee Related DE69222182D1 (de) 1991-12-18 1992-11-18 Verfahren für die herstellung einer festen dispersion

Country Status (17)

Country Link
US (3) US6677362B1 (de)
EP (1) EP0617612B1 (de)
JP (1) JP3722293B2 (de)
AT (1) AT157864T (de)
AU (1) AU671811B2 (de)
CA (1) CA2124821C (de)
DE (2) DE69222182D1 (de)
DK (1) DK0617612T3 (de)
ES (1) ES2109377T3 (de)
GR (1) GR3025501T3 (de)
IL (1) IL104179A (de)
MX (1) MX9207390A (de)
NZ (1) NZ245483A (de)
PT (1) PT101132B (de)
SG (1) SG43179A1 (de)
WO (1) WO1993011749A1 (de)
ZA (1) ZA9209789B (de)

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Also Published As

Publication number Publication date
AU3142693A (en) 1993-07-19
IL104179D0 (en) 1993-05-13
AU671811B2 (en) 1996-09-12
DE69222182D1 (de) 1997-10-16
PT101132B (pt) 2000-02-29
CA2124821A1 (en) 1993-06-24
NZ245483A (en) 1995-12-21
SG43179A1 (en) 1997-10-17
DK617612T3 (de)
EP0617612B1 (de) 1997-09-10
CA2124821C (en) 2003-10-07
WO1993011749A1 (en) 1993-06-24
ES2109377T3 (es) 1998-01-16
EP0617612A1 (de) 1994-10-05
US20010044409A1 (en) 2001-11-22
US20040110694A1 (en) 2004-06-10
ZA9209789B (en) 1993-06-23
US6677362B1 (en) 2004-01-13
JPH07504162A (de) 1995-05-11
AT157864T (de) 1997-09-15
MX9207390A (es) 1993-06-01
IL104179A (en) 1997-11-20
DK0617612T3 (da) 1998-04-14
GR3025501T3 (en) 1998-02-27
PT101132A (pt) 1994-03-31
JP3722293B2 (ja) 2005-11-30

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