JPS6051189B2
(ja)
*
|
1980-07-21 |
1985-11-12 |
株式会社日立製作所 |
磁気バブル駆動回路
|
JPS60226873A
(ja)
*
|
1984-03-28 |
1985-11-12 |
Sankyo Co Ltd |
1,3−ベンゾオキサチオ−ル誘導体及びその製法
|
CN1003445B
(zh)
*
|
1984-10-03 |
1989-03-01 |
武田药品工业株式会社 |
噻唑烷二酮衍生物,其制备方法和用途
|
JPH0653738B2
(ja)
*
|
1985-02-26 |
1994-07-20 |
三共株式会社 |
チアゾリジン誘導体
|
DK173350B1
(da)
*
|
1985-02-26 |
2000-08-07 |
Sankyo Co |
Thiazolidinderivater, deres fremstilling og farmaceutisk paæparat indeholdende dem
|
WO1986007056A1
(en)
*
|
1985-05-21 |
1986-12-04 |
Pfizer Inc. |
Hypoglycemic thiazolidinediones
|
US4738972A
(en)
*
|
1985-05-21 |
1988-04-19 |
Pfizer Inc. |
Hypoglycemic thiazolidinediones
|
JPH06779B2
(ja)
*
|
1985-06-10 |
1994-01-05 |
武田薬品工業株式会社 |
チアゾリジオン誘導体およびそれを含んでなる医薬組成物
|
JPS62234085A
(ja)
*
|
1985-12-18 |
1987-10-14 |
Sankyo Co Ltd |
チアゾリジン誘導体を有効成分とする糖尿病性合併症治療剤
|
US4873255A
(en)
*
|
1987-02-04 |
1989-10-10 |
Sankyo Company Limited |
Thiazolidinone derivatives, their preparation and their use
|
JP2574845B2
(ja)
*
|
1987-02-04 |
1997-01-22 |
三共株式会社 |
チアゾリジン化合物
|
US4798835A
(en)
*
|
1987-12-02 |
1989-01-17 |
Pfizer Inc. |
dl-5-[(2-benzyl-3,4-dihydro-2H-benzopyran-6-yl)methyl]thiazolidine-2,4-dione as an anti-atherosclerosis agent
|
US4791125A
(en)
*
|
1987-12-02 |
1988-12-13 |
Pfizer Inc. |
Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents
|
US5132310A
(en)
*
|
1988-08-09 |
1992-07-21 |
Hoffmann-La Roche Inc. |
Pharmacologically active chromanes
|
US5015661A
(en)
*
|
1988-08-09 |
1991-05-14 |
Hoffmann-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
US5260294A
(en)
*
|
1988-08-09 |
1993-11-09 |
Hoffman-La Roche Inc. |
Chromanes and their pharmaceutical compositions and methods
|
GB8919417D0
(en)
|
1989-08-25 |
1989-10-11 |
Beecham Group Plc |
Novel compounds
|
US5053420A
(en)
*
|
1989-10-13 |
1991-10-01 |
Pershadsingh Harrihar A |
Thiazolidine derivatives for the treatment of hypertension
|
JP2826379B2
(ja)
*
|
1990-01-22 |
1998-11-18 |
三共株式会社 |
チアゾリジン誘導体を有効成分とする肥満性高血圧症治療剤
|
US5143930A
(en)
*
|
1990-02-07 |
1992-09-01 |
Sankyo Company, Limited |
Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
|
US5356913A
(en)
*
|
1990-02-09 |
1994-10-18 |
The Upjohn Company |
Use of insulin sensitizing agents to treat hypertension
|
WO1991012003A1
(en)
*
|
1990-02-09 |
1991-08-22 |
The Upjohn Company |
Use of insulin sensitizing agents to treat hypertension
|
EP0454501B1
(en)
*
|
1990-04-27 |
2001-09-05 |
Sankyo Company Limited |
Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides
|
GB9023584D0
(en)
*
|
1990-10-30 |
1990-12-12 |
Beecham Group Plc |
Novel compounds
|
CA2082003A1
(en)
*
|
1991-11-20 |
1993-05-21 |
David Laffan |
Process for the preparation of substituted pentaalkylchromenes
|
DE69222182T2
(de)
*
|
1991-12-18 |
1998-02-26 |
Warner Lambert Co |
Verfahren für die herstellung einer festen dispersion
|
NO302519B1
(no)
*
|
1991-12-26 |
1998-03-16 |
Sankyo Co |
Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
|
NO302471B1
(no)
*
|
1991-12-26 |
1998-03-09 |
Sankyo Co |
Tiazolidinforbindelser og farmasöytisk preparat
|
CA2089013A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2, 5, 7, 8- tetraalkyl-2-(4-aminophenoxymethyl) chromans
|
CA2089012A1
(en)
*
|
1992-02-21 |
1993-08-22 |
Josef Heveling |
Process for the preparation of 6-hydroxy-2,5,7,8-tetra- alkyl-2-(4-aminophenoxymethyl) chromans
|
ES2139633T3
(es)
|
1992-08-31 |
2000-02-16 |
Sankyo Co |
Derivados de oxazolidina con propiedades anti-diabetica y anti-obesidad, su preparacion y su utilizacion terapeutica.
|
JPH0631079U
(ja)
*
|
1992-09-22 |
1994-04-22 |
沖電線株式会社 |
シート付き小型smtコネクタ
|
US5594016A
(en)
*
|
1992-12-28 |
1997-01-14 |
Mitsubishi Chemical Corporation |
Naphthalene derivatives
|
AU6114794A
(en)
*
|
1993-02-24 |
1994-09-14 |
Sankyo Company Limited |
Arteriosclerosis remedy
|
USRE39384E1
(en)
|
1993-09-01 |
2006-11-07 |
Smithkline Beecham P.L.C. |
Substituted thiazolidinedione derivatives
|
US5874454A
(en)
*
|
1993-09-15 |
1999-02-23 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
US6046222A
(en)
*
|
1993-09-15 |
2000-04-04 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
US5478852C1
(en)
*
|
1993-09-15 |
2001-03-13 |
Sankyo Co |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
|
AU749416B2
(en)
*
|
1993-09-15 |
2002-06-27 |
Daiichi Sankyo Company, Limited |
Use of thiazolidinediones to prevent or delay onset of NIDDM
|
HU228260B1
(en)
*
|
1993-09-15 |
2013-02-28 |
Daiichi Sankyo Company |
Pharmaceutical compositions to treat impaired glucose tolerance
|
CA2157032C
(en)
*
|
1993-12-27 |
1999-09-28 |
Hisashi Shinkai |
Isoxazolidinedione derivative and use thereof
|
RU2151145C1
(ru)
*
|
1994-04-11 |
2000-06-20 |
Санкио Компани Лимитед |
Промежуточное соединение для получения гетероциклических соединений, обладающих антидиабетической активностью
|
US5594015A
(en)
*
|
1994-06-22 |
1997-01-14 |
Regents Of The University Of California |
Thiazolidine derivatives for the treatment of psoriasis
|
US5703096A
(en)
|
1994-10-07 |
1997-12-30 |
Sankyo Company, Limited |
Oxime derivatives, their preparation and their therapeutic use
|
US5708012A
(en)
*
|
1995-04-28 |
1998-01-13 |
Sankyo Company, Limited |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus
|
IL118474A
(en)
*
|
1995-06-01 |
2001-08-08 |
Sankyo Co |
Benzimideol derivatives and pharmaceutical preparations containing them
|
US5798375A
(en)
*
|
1995-07-03 |
1998-08-25 |
Sankyo Company, Limited |
Treatment of arteriosclerosis and xanthoma
|
NZ313874A
(en)
*
|
1995-08-10 |
2000-09-29 |
Warner Lambert Co |
Compounds used as medicaments useful in eliminating the amount of exogenous insulin administered to a patient having noninsulin-dependent diabetes mellitus
|
AU7604596A
(en)
*
|
1995-11-17 |
1997-06-11 |
Warner-Lambert Company |
A method of treating myotonic dystrophy
|
EP0783888A1
(en)
|
1995-12-26 |
1997-07-16 |
Sankyo Company Limited |
Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
|
IN182496B
(fi)
*
|
1996-02-20 |
1999-04-17 |
Reddy Research Foundation |
|
IL120443A
(en)
*
|
1996-03-18 |
2000-07-16 |
Sankyo Co |
Use of an insulin sensitizer for the manufacture of a medicament for the treatment or prophylaxis of pancreatitis
|
AU708919B2
(en)
*
|
1996-04-04 |
1999-08-19 |
Sankyo Company Limited |
Phenylalkylcarboxylic acid derivatives
|
ATE231136T1
(de)
*
|
1996-04-09 |
2003-02-15 |
Reddys Lab Ltd Dr |
Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven eigenschaften, verfahren zu deren herstellung und pharmazeutischen zusammenstellungen, die sie enthalten
|
ZA973850B
(en)
*
|
1996-05-06 |
1997-12-02 |
Reddy Research Foundation |
Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
|
US5801173A
(en)
*
|
1996-05-06 |
1998-09-01 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
ZA973848B
(en)
*
|
1996-05-06 |
1997-12-02 |
Reddy Research Foundation |
Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
|
US5919782A
(en)
*
|
1996-05-06 |
1999-07-06 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
AU3091197A
(en)
*
|
1996-05-16 |
1997-12-05 |
Boehringer Mannheim Gmbh |
New process for preparing troglitazone
|
DE19619819A1
(de)
*
|
1996-05-16 |
1997-11-20 |
Boehringer Mannheim Gmbh |
Neue Thiazolidindione, Verfahren zu ihrer Herstellung und diese enthaltenden Arzneimittel
|
CA2257284C
(en)
*
|
1996-05-31 |
2005-10-04 |
Sankyo Company Limited |
Remedy for autoimmune diseases
|
GB9611947D0
(en)
*
|
1996-06-07 |
1996-08-07 |
Glaxo Group Ltd |
Medicaments
|
EP0844997A1
(en)
*
|
1996-06-19 |
1998-06-03 |
Dr. Reddy's Research Foundation |
Novel polymorphic forms of troglitazone having enhanced anti-diabetic activity and a process for their preparation
|
US6372750B2
(en)
|
1996-07-01 |
2002-04-16 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
|
US5985884A
(en)
*
|
1996-07-01 |
1999-11-16 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
US6114526A
(en)
*
|
1996-07-01 |
2000-09-05 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
USRE39266E1
(en)
*
|
1996-07-01 |
2006-09-05 |
Dr. Reddy's Laboratories, Limited |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
US5885997A
(en)
*
|
1996-07-01 |
1999-03-23 |
Dr. Reddy's Research Foundation |
Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
|
TR199900056T2
(xx)
*
|
1996-07-12 |
1999-04-21 |
Smithkline Beecham P.L.C. |
Leptin direncinin yeni tedavisi.
|
CN1235543A
(zh)
*
|
1996-09-12 |
1999-11-17 |
三共株式会社 |
含有曲格列酮的谷胱甘肽还原酶活性增强剂
|
DE69738809D1
(de)
*
|
1996-11-08 |
2008-08-14 |
Nippon Chemiphar Co |
Mittel zur verringerung der eigeweidefette
|
JP2001514663A
(ja)
*
|
1997-03-12 |
2001-09-11 |
エスモンド,ロバート ダブリュー. |
アルツハイマー病を処置または予防するための方法
|
US6313113B1
(en)
|
1997-04-15 |
2001-11-06 |
Reddy-Cheminor, Inc. |
Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
|
US6011031A
(en)
*
|
1997-05-30 |
2000-01-04 |
Dr. Reddy's Research Foundation |
Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
|
SE9702305D0
(sv)
*
|
1997-06-17 |
1997-06-17 |
Astra Ab |
New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
|
AU8539398A
(en)
*
|
1997-06-18 |
1999-01-04 |
Smithkline Beecham Plc |
Treatment of diabetes with thiazolidinedione and metformin
|
AU8539298A
(en)
*
|
1997-06-18 |
1999-01-04 |
Smithkline Beecham Plc |
Treatment of diabetes with thiazolidinedione and sulphonylurea
|
GB9715306D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
GB9715295D0
(en)
*
|
1997-07-18 |
1997-09-24 |
Smithkline Beecham Plc |
Novel method of treatment
|
US6171856B1
(en)
|
1997-07-30 |
2001-01-09 |
Board Of Regents, The University Of Texas System |
Methods and compositions relating to no-mediated cytotoxicity
|
FR2766820B1
(fr)
*
|
1997-07-31 |
1999-10-22 |
Rhodia Chimie Sa |
Procede de preparation de 2h-1-benzopyranes et intermediaires de synthese utiles dans la mise en oeuvre du procede
|
ID24376A
(id)
|
1997-10-02 |
2000-07-13 |
Sankyo Co |
Turunan-turunan asam amidokarboksilat
|
EP0916665A1
(de)
*
|
1997-11-11 |
1999-05-19 |
Lonza A.G. |
Verfahren zur Herstellung von Chromanderivaten
|
KR100567183B1
(ko)
*
|
1997-11-14 |
2006-06-13 |
론자 아게 |
포르밀이미다졸의제조방법
|
HUP9902721A2
(hu)
*
|
1997-11-25 |
1999-12-28 |
The Procter & Gamble Co. |
Tömény textillágyító készítmény és ehhez alkalmazható magas telítetlenségű textillágyító vegyület
|
AU1507799A
(en)
*
|
1997-12-16 |
1999-07-05 |
Sankyo Company Limited |
Leukemia remedy
|
US20040058873A1
(en)
*
|
1998-03-12 |
2004-03-25 |
Esmond Robert W. |
Method for treating or preventing Alzheimer's disease
|
AU736951C
(en)
|
1998-03-19 |
2003-02-20 |
Bristol-Myers Squibb Company |
Biphasic controlled release delivery system for high solubility pharmaceuticals and method
|
WO2000007582A2
(en)
*
|
1998-08-06 |
2000-02-17 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives for the treatment or prevention of cataracts
|
WO2000010994A1
(en)
*
|
1998-08-19 |
2000-03-02 |
Sankyo Company, Limited |
Process for the preparation of 2-(aryloxymethyl)-2,5,7,8-tetramethylchroman-6-ols
|
WO2000015229A1
(en)
|
1998-09-17 |
2000-03-23 |
Bristol-Myers Squibb Company |
METHOD FOR TREATING DIABETES EMPLOYING AN aP2 INHIBITOR AND COMBINATION
|
US6028088A
(en)
*
|
1998-10-30 |
2000-02-22 |
The University Of Mississippi |
Flavonoid derivatives
|
AR023700A1
(es)
|
1998-11-12 |
2002-09-04 |
Smithkline Beecham Plc |
Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
|
KR100643833B1
(ko)
|
1998-11-12 |
2006-11-10 |
스미스클라인비이참피이엘시이 |
인슐린 감작제 및 다른 항당뇨병 약제의 개선된 방출을위한 제약 조성물
|
GB9824893D0
(en)
*
|
1998-11-12 |
1999-01-06 |
Smithkline Beckman Corp |
Novel method of treatment
|
CA2350599A1
(en)
*
|
1998-11-20 |
2000-06-02 |
Genentech, Inc. |
Method of inhibiting angiogenesis
|
US6191154B1
(en)
|
1998-11-27 |
2001-02-20 |
Case Western Reserve University |
Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
|
US5968960A
(en)
*
|
1999-01-14 |
1999-10-19 |
The Regents Of The University Of California |
Use of thiazolidinediones to ameliorate the adverse consequences of myocardial ischemia on myocardial function and metabolism
|
US6127394A
(en)
*
|
1999-03-08 |
2000-10-03 |
The University Of Mississippi |
1,2-Dithiolane derivatives
|
US6204288B1
(en)
|
1999-03-08 |
2001-03-20 |
The University Of Mississippi |
1,2-dithiolane derivatives
|
US6548529B1
(en)
|
1999-04-05 |
2003-04-15 |
Bristol-Myers Squibb Company |
Heterocyclic containing biphenyl aP2 inhibitors and method
|
US7041691B1
(en)
*
|
1999-06-30 |
2006-05-09 |
Amgen Inc. |
Compounds for the modulation of PPARγ activity
|
JP2001072592A
(ja)
|
1999-07-01 |
2001-03-21 |
Kyowa Hakko Kogyo Co Ltd |
テロメラーゼ阻害剤
|
AR028299A1
(es)
|
1999-09-17 |
2003-05-07 |
Novartis Ag |
Una composicion farmaceutica que comprende nateglinida, un proceso para su preparacion y el uso de dicha composicion para la preparacion de un medicamento para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con diabetes.
|
US6559188B1
(en)
|
1999-09-17 |
2003-05-06 |
Novartis Ag |
Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
|
US6878749B2
(en)
|
1999-09-17 |
2005-04-12 |
Novartis Ag |
Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
|
US6586438B2
(en)
|
1999-11-03 |
2003-07-01 |
Bristol-Myers Squibb Co. |
Antidiabetic formulation and method
|
PL356769A1
(en)
|
1999-12-03 |
2004-07-12 |
Kyoto Pharmaceutical Industries, Ltd. |
Novel heterocyclic compounds and salts thereof and medicinal use of the same
|
ES2433476T3
(es)
|
2000-01-21 |
2013-12-11 |
Novartis Ag |
Combinaciones que contienen inhibidores de la dipeptidilpeptidasa-IV y agentes 5 antidiabéticos
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
US6680387B2
(en)
*
|
2000-04-24 |
2004-01-20 |
Aryx Therapeutics |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
US6958355B2
(en)
*
|
2000-04-24 |
2005-10-25 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
US6653332B2
(en)
*
|
2000-05-03 |
2003-11-25 |
Tularik Inc. |
Combination therapeutic compositions and method of use
|
GB0014969D0
(en)
|
2000-06-19 |
2000-08-09 |
Smithkline Beecham Plc |
Novel method of treatment
|
US20030171399A1
(en)
*
|
2000-06-28 |
2003-09-11 |
Tularik Inc. |
Quinolinyl and benzothiazolyl modulators
|
SK2102003A3
(en)
|
2000-08-07 |
2003-08-05 |
Ranbaxy Signature Llc |
Liquid formulation of metformin
|
AU2001294673A1
(en)
*
|
2000-09-21 |
2002-04-02 |
Aryx Therapeutics |
Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, andatherosclerosis
|
FR2816840B1
(fr)
*
|
2000-11-17 |
2004-04-09 |
Flamel Tech Sa |
Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
|
US6452014B1
(en)
|
2000-12-22 |
2002-09-17 |
Geron Corporation |
Telomerase inhibitors and methods of their use
|
AU2002254567B2
(en)
|
2001-04-11 |
2007-10-11 |
Bristol-Myers Squibb Company |
Amino acid complexes of C-aryl glucosides for treatment of diabetes and method
|
US20060047000A1
(en)
*
|
2001-04-24 |
2006-03-02 |
Aryx Therapeutics, Inc. |
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
|
EP1398313A4
(en)
*
|
2001-05-29 |
2005-11-16 |
Kyoto Pharma Ind |
NEW HETEROCYCLIC DERIVATIVES AND THEIR MEDICAL USE
|
PL367639A1
(en)
*
|
2001-05-29 |
2005-03-07 |
Kyoto Pharmaceutical Industries, Ltd. |
Novel heterocyclic compound and medicinal use thereof
|
JP4152641B2
(ja)
*
|
2001-08-07 |
2008-09-17 |
クラシエ製薬株式会社 |
チアゾリジン誘導体の副作用軽減剤
|
US8101209B2
(en)
*
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
FR2830447B1
(fr)
*
|
2001-10-09 |
2004-04-16 |
Flamel Tech Sa |
Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
AU2002348276A1
(en)
*
|
2001-11-16 |
2003-06-10 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
US7015345B2
(en)
*
|
2002-02-21 |
2006-03-21 |
Asahi Kasei Pharma Corporation |
Propionic acid derivatives
|
IL163666A0
(en)
|
2002-02-22 |
2005-12-18 |
New River Pharmaceuticals Inc |
Active agent delivery systems and methods for protecting and administering active agents
|
CA2480826C
(fr)
|
2002-04-09 |
2012-02-07 |
Flamel Technologies |
Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
|
IL164221A0
(en)
*
|
2002-04-09 |
2005-12-18 |
Flamel Tech Sa |
Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillim
|
CN100471047C
(zh)
*
|
2002-05-14 |
2009-03-18 |
西门子公司 |
用于产生发射信号的方法
|
US8268352B2
(en)
*
|
2002-08-05 |
2012-09-18 |
Torrent Pharmaceuticals Limited |
Modified release composition for highly soluble drugs
|
US8216609B2
(en)
*
|
2002-08-05 |
2012-07-10 |
Torrent Pharmaceuticals Limited |
Modified release composition of highly soluble drugs
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
WO2004066929A2
(en)
*
|
2003-01-24 |
2004-08-12 |
Bristol-Myers Squibb Company |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
US7723509B2
(en)
|
2003-04-17 |
2010-05-25 |
Alnylam Pharmaceuticals |
IRNA agents with biocleavable tethers
|
US7851615B2
(en)
*
|
2003-04-17 |
2010-12-14 |
Alnylam Pharmaceuticals, Inc. |
Lipophilic conjugated iRNA agents
|
US8796436B2
(en)
|
2003-04-17 |
2014-08-05 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
US8017762B2
(en)
*
|
2003-04-17 |
2011-09-13 |
Alnylam Pharmaceuticals, Inc. |
Modified iRNA agents
|
ES2702942T3
(es)
*
|
2003-04-17 |
2019-03-06 |
Alnylam Pharmaceuticals Inc |
Agentes de ARNi modificados
|
US20050004179A1
(en)
*
|
2003-05-22 |
2005-01-06 |
Pedersen Ward A. |
Methods and materials for treating, detecting, and reducing the risk of developing Alzheimer's Disease
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
US7371759B2
(en)
*
|
2003-09-25 |
2008-05-13 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
US7223761B2
(en)
*
|
2003-10-03 |
2007-05-29 |
Amgen Inc. |
Salts and polymorphs of a potent antidiabetic compound
|
PL1689757T3
(pl)
*
|
2003-11-12 |
2015-05-29 |
Sino Med Int Alliance Inc |
Heterocykliczne związki kwasu boronowego
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7420059B2
(en)
*
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
EP1778220A1
(en)
*
|
2004-07-12 |
2007-05-02 |
Phenomix Corporation |
Constrained cyano compounds
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
KR20070086007A
(ko)
*
|
2004-12-13 |
2007-08-27 |
다이이찌 산쿄 가부시키가이샤 |
당뇨병의 치료를 위한 의약 조성물
|
US7317024B2
(en)
|
2005-01-13 |
2008-01-08 |
Bristol-Myers Squibb Co. |
Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
WO2006086464A2
(en)
*
|
2005-02-10 |
2006-08-17 |
Bristol-Myers Squibb Company |
Dihydroquinazolinones as 5ht modulators
|
US20070269486A1
(en)
*
|
2005-03-14 |
2007-11-22 |
Conor Medsystems, Llc. |
Methods and Devices for Reducing Tissue Damage After Ischemic Injury
|
EP1858845A2
(en)
*
|
2005-03-18 |
2007-11-28 |
Orchid Chemicals and Pharmaceuticals Limited |
Novel tyrosine derivatives
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7888381B2
(en)
|
2005-06-14 |
2011-02-15 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity, and use thereof
|
AU2006275694A1
(en)
*
|
2005-07-28 |
2007-02-08 |
Bristol-Myers Squibb Company |
Substituted tetrahydro-1H-pyrido(4,3,b)indoles as serotonin receptor agonists and antagonists
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
US20080064884A1
(en)
*
|
2006-05-10 |
2008-03-13 |
Astrazeneca Ab |
Novel Process 1
|
EP2089389A2
(en)
|
2006-11-01 |
2009-08-19 |
Bristol-Myers Squibb Company |
Heterocyclic compounds as modulators of glucocorticoid receptor, ap-1, and/or nf-kappa-b activity
|
WO2008057862A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
|
EP2099767A1
(en)
|
2006-11-01 |
2009-09-16 |
Brystol-Myers Squibb Company |
Modulators of glucocorticoid receptor, ap-1, and/or nf- b activity and use thereof
|
CN104163864B
(zh)
|
2007-03-30 |
2017-08-01 |
Ambrx公司 |
经修饰fgf‑21多肽和其用途
|
US20160331729A9
(en)
|
2007-04-11 |
2016-11-17 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
US11241420B2
(en)
|
2007-04-11 |
2022-02-08 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
EP3053440B1
(en)
|
2007-04-11 |
2020-08-12 |
Omeros Corporation |
Compositions and methods for prophylaxis and treatment of addictions
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
MX354786B
(es)
|
2007-06-04 |
2018-03-21 |
Synergy Pharmaceuticals Inc |
Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
|
ES2448839T3
(es)
|
2007-11-01 |
2014-03-17 |
Bristol-Myers Squibb Company |
Compuestos no esteroideos útiles como moderadores de la actividad del receptor de glucocorticoides AP-1 y/o NF-kappa b y uso de los mismos
|
CA2726917C
(en)
|
2008-06-04 |
2018-06-26 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
WO2010009319A2
(en)
|
2008-07-16 |
2010-01-21 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
SG172363A1
(en)
|
2008-12-23 |
2011-07-28 |
Pharmasset Inc |
Synthesis of purine nucleosides
|
CL2009002207A1
(es)
|
2008-12-23 |
2011-02-18 |
Gilead Pharmasset Llc |
Compuestos derivados de 3-hidroxi-5-(9h-purin-9-il)tetrahidrofuran-2-il, inhibidor de la replicacion de arn viral dependiente de arn; composicion farmaceutica; uso para el tratamiento de hepatitis c.
|
WO2010075517A2
(en)
*
|
2008-12-23 |
2010-07-01 |
Pharmasset, Inc. |
Nucleoside analogs
|
BRPI1009141A2
(pt)
|
2009-03-11 |
2016-03-08 |
Omeros Corp |
composições e métodos para profilaxia e tratamento de vícios
|
AU2011207210A1
(en)
|
2010-01-22 |
2012-08-16 |
Dana-Farber Cancer Institute, Inc. |
Compositions,kits, and methods for identification, assessment, prevention, and therapy of metabolic disorders
|
AP3515A
(en)
|
2010-03-31 |
2016-01-11 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
JP6042330B2
(ja)
|
2010-07-09 |
2016-12-14 |
ビーエイチヴィ ファーマ、インコーポレイテッド |
レモグリフロジンを含めた半減期が短い医薬品のための組合せ即時/遅延放出送達システム
|
US20130156720A1
(en)
|
2010-08-27 |
2013-06-20 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
US20120094959A1
(en)
|
2010-10-19 |
2012-04-19 |
Bonnie Blazer-Yost |
Treatment of cystic diseases
|
WO2014057522A1
(en)
|
2012-10-12 |
2014-04-17 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
WO2014068397A1
(en)
|
2012-11-05 |
2014-05-08 |
Commissariat A L'energie Atomique Et Aux Energies Atlternatives (Cea) |
Combination of an anti-cancer agent such as a tyrosinekinase inhibitor and a stat5 antagonist, preferably a thiazolidinedione, for eliminating hematologic cancer stem cells in vivo and for preventing hematologic cancer relapse
|
SG11201507288UA
(en)
|
2013-03-15 |
2015-10-29 |
Mochida Pharm Co Ltd |
Compositions and methods for treating non-alcoholic steatohepatitis
|
WO2014151200A2
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
US10441560B2
(en)
|
2013-03-15 |
2019-10-15 |
Mochida Pharmaceutical Co., Ltd. |
Compositions and methods for treating non-alcoholic steatohepatitis
|
EP2970384A1
(en)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
JP6606491B2
(ja)
|
2013-06-05 |
2019-11-13 |
シナジー ファーマシューティカルズ インコーポレイテッド |
グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法
|
WO2015027021A1
(en)
|
2013-08-22 |
2015-02-26 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
CA2926685A1
(en)
|
2013-10-09 |
2015-04-16 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines
|
PL3412302T3
(pl)
|
2014-10-24 |
2021-11-02 |
Bristol-Myers Squibb Company |
Zmodyfikowane polipeptydy fgf-21 i ich zastosowania
|
WO2016071727A1
(en)
|
2014-11-04 |
2016-05-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
|
AU2019304032B2
(en)
|
2018-07-19 |
2021-12-09 |
Astrazeneca Ab |
Methods of treating HFpEF employing dapagliflozin and compositions comprising the same
|
WO2022022865A1
(en)
|
2020-07-27 |
2022-02-03 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
CN118510504A
(zh)
|
2022-01-26 |
2024-08-16 |
阿斯利康(瑞典)有限公司 |
用于在治疗糖尿病前期或降低发展2型糖尿病的风险中使用的达格列净
|