DE2518160A1 - Neue aminosaeurederivate und verfahren zu ihrer herstellung - Google Patents

Neue aminosaeurederivate und verfahren zu ihrer herstellung

Info

Publication number
DE2518160A1
DE2518160A1 DE19752518160 DE2518160A DE2518160A1 DE 2518160 A1 DE2518160 A1 DE 2518160A1 DE 19752518160 DE19752518160 DE 19752518160 DE 2518160 A DE2518160 A DE 2518160A DE 2518160 A1 DE2518160 A1 DE 2518160A1
Authority
DE
Germany
Prior art keywords
group
compounds
general formula
salts
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19752518160
Other languages
German (de)
English (en)
Other versions
DE2518160C2 (es
Inventor
Geb Dobay Erzsebet Bendefy
Laszlo Feuer
Arpad Furka
Geb Szepespataky Jolan Hercsel
Ferenc Sebestyen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU74FE00000928A external-priority patent/HU171576B/hu
Priority claimed from HU74CI1558A external-priority patent/HU174114B/hu
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of DE2518160A1 publication Critical patent/DE2518160A1/de
Application granted granted Critical
Publication of DE2518160C2 publication Critical patent/DE2518160C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE19752518160 1974-04-29 1975-04-24 Neue aminosaeurederivate und verfahren zu ihrer herstellung Granted DE2518160A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU74FE00000928A HU171576B (hu) 1974-04-29 1974-04-29 Sposob otdelenija gamma-l-glutamil-taurina
HU74CI1558A HU174114B (hu) 1975-03-26 1975-03-26 Sposob poluchenija novykh proizvodnykh aminokislot

Publications (2)

Publication Number Publication Date
DE2518160A1 true DE2518160A1 (de) 1975-11-20
DE2518160C2 DE2518160C2 (es) 1993-05-06

Family

ID=26318406

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2559989A Expired DE2559989C3 (de) 1974-04-29 1975-04-24 Polymere und Verfahren zu ihrer Herstellung
DE19752518160 Granted DE2518160A1 (de) 1974-04-29 1975-04-24 Neue aminosaeurederivate und verfahren zu ihrer herstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2559989A Expired DE2559989C3 (de) 1974-04-29 1975-04-24 Polymere und Verfahren zu ihrer Herstellung

Country Status (23)

Country Link
JP (1) JPS6012347B2 (es)
AR (3) AR218221A1 (es)
AT (6) AT361902B (es)
AU (1) AU499173B2 (es)
BE (1) BE828546A (es)
BG (4) BG26368A3 (es)
CA (1) CA1051802A (es)
CH (4) CH617183A5 (es)
CS (4) CS209855B2 (es)
DD (2) DD125070A5 (es)
DE (2) DE2559989C3 (es)
DK (10) DK155433C (es)
EG (1) EG11847A (es)
ES (4) ES436986A1 (es)
FI (1) FI65990C (es)
FR (1) FR2279388A1 (es)
GB (1) GB1504541A (es)
IL (1) IL47149A (es)
NL (1) NL183186C (es)
NO (2) NO146430C (es)
PL (2) PL111745B1 (es)
SE (2) SE430164B (es)
SU (1) SU747419A3 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2719351A1 (de) * 1976-05-06 1977-11-17 Chinoin Gyogyszer Es Vegyeszet Neue omega-aminocarbonsaeureamide und verfahren zu ihrer herstellung

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180443B (en) * 1979-04-02 1983-03-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing a pharmaceutical preparation with synergetic action against radiation
HU185632B (en) * 1981-03-27 1985-03-28 Chinoin Gyogyszer Es Vegyeszet New process for preparing gamma-glutamyl-taurine
CH665645A5 (fr) * 1981-07-09 1988-05-31 Michel Flork Derives de dipeptides et leur procede de preparation.
HU208072B (en) * 1990-02-28 1993-08-30 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical composition suitable for preventing and curing autoimmune diseases and skin affections caused by heat and light radiacion
JPH0680964A (ja) * 1991-12-27 1994-03-22 Sogo Yatsukou Kk 活性酸素消去剤
JPH11180846A (ja) * 1997-12-15 1999-07-06 Sogo Pharmaceut Co Ltd 化粧料
DE10133197A1 (de) * 2001-07-07 2003-01-23 Beiersdorf Ag Aminosäuren enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut
DK2089417T3 (en) * 2006-10-12 2015-03-23 Bhi Ltd Partnership Methods, Compounds, Compositions and Vehicles for Delivery of 3-Amion-1-Propanesulfonic Acid
US9662304B1 (en) * 2013-06-13 2017-05-30 Thermolife International, Llc Substituted glutaurine compounds and substituted glutaurine derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2234832A1 (de) * 1971-08-04 1973-04-05 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung von litoralon

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2234832A1 (de) * 1971-08-04 1973-04-05 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung von litoralon

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemie in unserer Zeit, 14.Jhg. 1980, Nr.6, S.183 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2719351A1 (de) * 1976-05-06 1977-11-17 Chinoin Gyogyszer Es Vegyeszet Neue omega-aminocarbonsaeureamide und verfahren zu ihrer herstellung
US4102948A (en) * 1976-05-06 1978-07-25 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. ω-Aminocarboxylic acid amide phosphates

Also Published As

Publication number Publication date
IL47149A0 (en) 1975-06-25
AT361902B (de) 1981-04-10
NL7505075A (nl) 1975-10-31
ES436986A1 (es) 1977-06-16
CH617183A5 (es) 1980-05-14
CH621333A5 (es) 1981-01-30
DK158676C (da) 1991-01-14
SU747419A3 (ru) 1980-07-23
CS209855B2 (en) 1981-12-31
DK442877A (da) 1977-10-06
FI65990B (fi) 1984-04-30
CH624098A5 (es) 1981-07-15
DK155520C (da) 1989-10-16
DK182875A (da) 1975-10-30
DK155433B (da) 1989-04-10
FR2279388A1 (fr) 1976-02-20
DK442477A (da) 1977-10-06
DK158676B (da) 1990-07-02
DK159654B (da) 1990-11-12
DK245783A (da) 1983-05-31
JPS6012347B2 (ja) 1985-04-01
DK159267C (da) 1991-02-18
NO149036B (no) 1983-10-24
CS209856B2 (en) 1981-12-31
NO146430C (no) 1982-09-29
ATA624777A (de) 1980-03-15
DE2559989C3 (de) 1981-11-19
AU8056475A (en) 1976-11-04
ATA314075A (de) 1980-09-15
DK442977A (da) 1977-10-06
BG26369A4 (es) 1979-03-15
EG11847A (en) 1979-06-30
NO751504L (es) 1975-10-30
ATA323179A (de) 1982-09-15
ATA323079A (de) 1983-09-15
NO810816L (no) 1975-10-30
PL111746B1 (en) 1980-09-30
ES453305A1 (es) 1977-11-16
DE2518160C2 (es) 1993-05-06
DK442777A (da) 1977-10-06
AT359085B (de) 1980-10-27
SE7504828L (sv) 1975-10-30
SE430164B (sv) 1983-10-24
AT370724B (de) 1983-04-25
JPS514121A (es) 1976-01-14
AT374484B (de) 1984-04-25
DK442677A (da) 1977-10-06
ATA624977A (de) 1978-12-15
FI65990C (fi) 1984-08-10
DK245783D0 (da) 1983-05-31
DE2559989B1 (de) 1981-02-05
CH621334A5 (es) 1981-01-30
BG26370A4 (es) 1979-03-15
SE7812884L (sv) 1978-12-14
ES453306A1 (es) 1977-11-16
AT359084B (de) 1980-10-27
BG26368A3 (es) 1979-03-15
DK159654C (da) 1991-04-08
AR218221A1 (es) 1980-05-30
NL183186C (nl) 1988-08-16
AT351007B (de) 1979-07-10
FR2279388B1 (es) 1978-07-28
AU499173B2 (en) 1979-04-05
AR218222A1 (es) 1980-05-30
PL111745B1 (en) 1980-09-30
DK155672C (da) 1989-10-09
ATA624877A (de) 1980-03-15
CA1051802A (en) 1979-04-03
DK442577A (da) 1977-10-06
DK155520B (da) 1989-04-17
ES453304A1 (es) 1977-11-16
DK443077A (da) 1977-10-06
CS209857B2 (en) 1981-12-31
NO146430B (no) 1982-06-21
DK442377A (da) 1977-10-06
DK155732C (da) 1989-10-02
DD122377A5 (es) 1976-10-05
BG26517A4 (es) 1979-04-12
GB1504541A (en) 1978-03-22
FI751256A (es) 1975-10-30
DK155732B (da) 1989-05-08
NO149036C (no) 1984-02-01
IL47149A (en) 1979-05-31
BE828546A (fr) 1975-08-18
CS209858B2 (en) 1981-12-31
AR217236A1 (es) 1980-03-14
DK155433C (da) 1989-10-16
SE441356B (sv) 1985-09-30
DK159267B (da) 1990-09-24
DD125070A5 (es) 1977-03-30
DK155672B (da) 1989-05-01

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Legal Events

Date Code Title Description
OI Miscellaneous see part 1
OI Miscellaneous see part 1
8128 New person/name/address of the agent

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