CY1111073T1 - Φαρμακευτικα προϊοντα σε διαλυμα που περιεχουν αντισωμα - Google Patents

Φαρμακευτικα προϊοντα σε διαλυμα που περιεχουν αντισωμα

Info

Publication number
CY1111073T1
CY1111073T1 CY20111100012T CY111100012T CY1111073T1 CY 1111073 T1 CY1111073 T1 CY 1111073T1 CY 20111100012 T CY20111100012 T CY 20111100012T CY 111100012 T CY111100012 T CY 111100012T CY 1111073 T1 CY1111073 T1 CY 1111073T1
Authority
CY
Cyprus
Prior art keywords
solution
antibody
solution containing
containing antibody
organic acid
Prior art date
Application number
CY20111100012T
Other languages
English (en)
Inventor
Masaya Kakuta
Jun Kikuchi
Hidefumi Mizushima
Yoshimi Imaeda
Original Assignee
Chugai Seiyaku Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27678080&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1111073(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Seiyaku Kabushiki Kaisha filed Critical Chugai Seiyaku Kabushiki Kaisha
Publication of CY1111073T1 publication Critical patent/CY1111073T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Φαρμακοτεχνική μορφή σε διάλυμα που περιέχει αντίσωμα περιλαμβάνουσα οργανικό οξύ και ένα επιφανειοδραστικό σταθεροποιητή, μέθοδος καταστολής του σχηματισμού ορατής αδιάλυτης ύλης ή/και αδιάλυτων σωματιδίων λόγω της παρουσίας μεταλλικών ιόντων σε μία φαρμακοτεχνική μορφή σε διάλυμα περιέχουσα αντίσωμα, που περιλαμβάνει προσθήκη οργανικού οξέος στο διάλυμα, μέθοδος καταστολής του σχηματισμού ορατής αδιάλυτης ύλης ή/και αδιάλυτων σωματιδίων κατά την διάρκεια της ανακίνησης και της κατάψυξης-επανατήξης ενός διαλύματος που περιέχει αντίσωμα, που περιλαμβάνει προσθήκη επιφανειοδραστικού στο διάλυμα και μέθοδος σταθεροποίησης ενός διαλύματος που περιέχει αντίσωμα που περιλαμβάνει προσθήκη οργανικού οξέος και ενός επιφανειοδραστικού.
CY20111100012T 2002-02-14 2011-01-04 Φαρμακευτικα προϊοντα σε διαλυμα που περιεχουν αντισωμα CY1111073T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002036244 2002-02-14
PCT/JP2003/001563 WO2003068260A1 (en) 2002-02-14 2003-02-14 Antibody-containing solution pharmaceuticals

Publications (1)

Publication Number Publication Date
CY1111073T1 true CY1111073T1 (el) 2012-01-25

Family

ID=27678080

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20111100012T CY1111073T1 (el) 2002-02-14 2011-01-04 Φαρμακευτικα προϊοντα σε διαλυμα που περιεχουν αντισωμα
CY2011003C CY2011003I2 (el) 2002-02-14 2011-03-22 Φαρμακευτικα προϊοντα σε διαλυμα που περιεχουν αντισωμα

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY2011003C CY2011003I2 (el) 2002-02-14 2011-03-22 Φαρμακευτικα προϊοντα σε διαλυμα που περιεχουν αντισωμα

Country Status (25)

Country Link
US (4) US20050118163A1 (el)
EP (5) EP3192528A1 (el)
JP (4) JP4364645B2 (el)
KR (3) KR101080021B1 (el)
CN (3) CN101066450A (el)
AT (1) ATE485835T1 (el)
AU (3) AU2003211991B2 (el)
BR (1) BRPI0307702B8 (el)
CA (1) CA2474943C (el)
CO (1) CO5611163A2 (el)
CY (2) CY1111073T1 (el)
DE (1) DE60334678D1 (el)
DK (1) DK1475101T3 (el)
ES (2) ES2353496T3 (el)
HR (1) HRP20040710B1 (el)
IL (1) IL163354A (el)
MX (1) MXPA04007924A (el)
NO (1) NO333553B1 (el)
NZ (1) NZ534542A (el)
PL (1) PL213311B1 (el)
PT (1) PT1475101E (el)
RU (1) RU2335299C2 (el)
SI (1) SI1475101T1 (el)
WO (2) WO2003068260A1 (el)
ZA (1) ZA200406230B (el)

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US20050118163A1 (en) 2005-06-02
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