US3378587A
(en)
|
1963-03-14 |
1968-04-16 |
Du Pont |
3, 3'-diaminomethyl-1, 1'-biadamantane
|
NL127995C
(es)
|
1963-12-20 |
|
Geigy Ag J R |
|
US3341538A
(en)
|
1965-06-18 |
1967-09-12 |
Geigy Chem Corp |
Certain 2, 6-methano-3-benzazocines
|
DE2108954A1
(en)
|
1971-02-25 |
1972-09-07 |
Boehringer Sohn Ingelheim |
2-(furylmethyl)-6,7-benzomorphans - useful as cns active agents
|
DE1801556A1
(de)
|
1968-10-05 |
1970-05-21 |
Huels Chemische Werke Ag |
Verfahren zur Herstellung von substituierten Hexahydropyrimidinonen-(2)
|
GB1304175A
(es)
|
1969-03-31 |
1973-01-24 |
|
|
DE2105743C3
(de)
|
1971-02-08 |
1979-11-29 |
Boehringer Sohn Ingelheim |
2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung
|
US3681349A
(en)
*
|
1970-03-05 |
1972-08-01 |
Morton Norwich Products Inc |
1-(substituted benzyl) tetrahydro-2-(1h) pyrimidones
|
US4043927A
(en)
|
1972-03-07 |
1977-08-23 |
Sun Ventures, Inc. |
Friction or tractive drive containing ethers of adamantanes
|
DE2229695A1
(de)
|
1972-06-19 |
1974-01-31 |
Boehringer Sohn Ingelheim |
2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
|
DE2338369A1
(de)
|
1973-07-26 |
1975-02-13 |
Schering Ag |
Mikrobiologische hydroxylierung von 2,6-methano-3-benzazocinen
|
SU510999A3
(ru)
|
1973-10-27 |
1976-04-15 |
К.Х.Берингер Зон, (Фирма) |
Способ получени (метоксиметил-фурилметил)6,7-бензоморфанов илиморфинанов
|
US4009171A
(en)
|
1974-02-21 |
1977-02-22 |
Sterling Drug Inc. |
N-acylated-11-oxygenated-2,6-methano-3-benzazocine intermediates
|
DE2411382C3
(de)
|
1974-03-09 |
1979-09-06 |
C.H. Boehringer Sohn, 6507 Ingelheim |
2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung
|
US4136145A
(en)
|
1974-07-05 |
1979-01-23 |
Schering Aktiengesellschaft |
Medicament carriers in the form of film having active substance incorporated therein
|
US4136162A
(en)
|
1974-07-05 |
1979-01-23 |
Schering Aktiengesellschaft |
Medicament carriers in the form of film having active substance incorporated therein
|
DE2437610A1
(de)
|
1974-08-05 |
1976-02-26 |
Boehringer Sohn Ingelheim |
Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
|
GB1513961A
(en)
|
1975-02-25 |
1978-06-14 |
Acf Chemiefarma Nv |
6,7-benzomorphans method for their preparation and intermediates
|
US4108857A
(en)
|
1975-08-18 |
1978-08-22 |
Sterling Drug Inc. |
Imidazolylmethyl methanobenzazocines
|
DE2828039A1
(de)
|
1978-06-26 |
1980-01-10 |
Boehringer Sohn Ingelheim |
2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
|
CA2023492A1
(en)
|
1989-08-31 |
1991-03-01 |
Barry Clifford Lange |
Herbicidal glutarimides
|
US5393735A
(en)
|
1990-08-09 |
1995-02-28 |
Rohm And Haas Company |
Herbicidal glutarimides
|
US5098916A
(en)
|
1990-03-29 |
1992-03-24 |
G. D. Searle & Co. |
Propanobicyclic amine derivatives for cns disorders
|
EP0454444A1
(en)
|
1990-04-24 |
1991-10-30 |
Nissan Chemical Industries Ltd. |
Glutarimide derivatives and herbicides
|
US5089506A
(en)
|
1990-04-30 |
1992-02-18 |
G. D. Searle & Co. |
Ethanobicyclic amine derivatives for cns disorders
|
US5215992A
(en)
|
1990-04-30 |
1993-06-01 |
G. D. Searle & Co. |
Ethanobicyclic amine derivatives for CNS disorders
|
DK204291D0
(da)
|
1991-12-20 |
1991-12-20 |
Novo Nordisk As |
Heterocykliske forbindelser deres fremstilling og anvendelse
|
CA2049244A1
(en)
|
1990-08-16 |
1992-02-17 |
Steven H. Christiansen |
Process for absorption of sulfur compounds from fluids using heterocyclic compounds having at least one ring nitrogen atom
|
WO1992006971A1
(en)
|
1990-10-10 |
1992-04-30 |
Schering Corporation |
Pyridine and pyridine n-oxide derivatives of diaryl methyl piperidines or piperazines, and compositions and methods of use thereof
|
GB9023583D0
(en)
|
1990-10-30 |
1990-12-12 |
Beecham Group Plc |
Novel compounds
|
US5610294A
(en)
|
1991-10-11 |
1997-03-11 |
The Du Pont Merck Pharmaceutical Company |
Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
|
DE69221309T2
(de)
|
1991-10-11 |
1997-12-11 |
The Du Pont Merck Pharmaceutical Co., Wilmington, Del. |
Cyclische harnstoffe und analoga verwendbar als retrovirale proteasehemmer
|
KR0146931B1
(ko)
|
1992-04-30 |
1998-08-17 |
고바야시 유끼오 |
옥사졸리딘 유도체 및 그의 약학적으로 허용가능한 염
|
GB9225377D0
(en)
|
1992-12-04 |
1993-01-27 |
Ici Plc |
Herbicides
|
US5521202A
(en)
|
1993-04-07 |
1996-05-28 |
Taiho Pharmaceutical Co., Ltd. |
Thiazolidine derivatives and pharmaceutical compositions containing the same
|
TW280812B
(es)
|
1993-07-02 |
1996-07-11 |
Bayer Ag |
|
EP0640594A1
(en)
|
1993-08-23 |
1995-03-01 |
Fujirebio Inc. |
Hydantoin derivative as metalloprotease inhibitor
|
DE19500118A1
(de)
|
1994-05-18 |
1995-11-23 |
Bayer Ag |
Substituierte Diazacyclohexandi(thi)one
|
JP3948744B2
(ja)
|
1994-11-04 |
2007-07-25 |
大日本住友製薬株式会社 |
新規なラクタム誘導体
|
US5780466A
(en)
|
1995-01-30 |
1998-07-14 |
Sanofi |
Substituted heterocyclic compounds method of preparing them and pharmaceutical compositions in which they are present
|
FR2729954B1
(fr)
|
1995-01-30 |
1997-08-01 |
Sanofi Sa |
Composes heterocycliques substitues, procede pour leur preparation et compositions pharmaceutiques les contenant
|
GB9510459D0
(en)
|
1995-05-24 |
1995-07-19 |
Zeneca Ltd |
Bicyclic amines
|
US5776959A
(en)
|
1995-06-05 |
1998-07-07 |
Washington University |
Anticonvulsant and anxiolytic lactam and thiolactam derivatives
|
GB9517622D0
(en)
|
1995-08-29 |
1995-11-01 |
Univ Edinburgh |
Regulation of intracellular glucocorticoid concentrations
|
AU717190B2
(en)
|
1996-04-03 |
2000-03-23 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
CA2262502C
(en)
|
1996-07-31 |
2002-11-26 |
Nikken Chemicals Co., Ltd. |
6-phenyltetrahydro-1,3-oxazin-2-one derivatives and pharmaceutical composition containing the same
|
US6794390B2
(en)
|
1996-08-02 |
2004-09-21 |
Cv Therapeutics, Inc. |
Purine inhibitors of cyclin dependent kinase 2 & ikappabalpha
|
US5866702A
(en)
|
1996-08-02 |
1999-02-02 |
Cv Therapeutics, Incorporation |
Purine inhibitors of cyclin dependent kinase 2
|
GB9623944D0
(en)
|
1996-11-15 |
1997-01-08 |
Zeneca Ltd |
Bicyclic amine derivatives
|
EP0988295A4
(en)
|
1997-06-18 |
2003-08-13 |
Synaptic Pharma Corp |
HETEROCYCLIC SUBSTITUTED PIPERIDINES AND USES THEREOF
|
US6159990A
(en)
|
1997-06-18 |
2000-12-12 |
Synaptic Pharmaceutical Corporation |
Oxazolidinones as α1A receptor antagonists
|
DE19731784A1
(de)
|
1997-07-24 |
1999-02-04 |
Bayer Ag |
Substituierte N-Aryl-N-thioxocarbonyl-sulfonamide
|
GB9715892D0
(en)
|
1997-07-29 |
1997-10-01 |
Zeneca Ltd |
Heterocyclic compounds
|
US5912114A
(en)
|
1997-09-12 |
1999-06-15 |
Johnson & Johnson Medical, Inc. |
Wound diagnosis by quantitating cortisol in wound fluids
|
US5936124A
(en)
|
1998-06-22 |
1999-08-10 |
Sepacor Inc. |
Fluoxetine process from benzoylpropionic acid
|
US7410995B1
(en)
|
1998-08-14 |
2008-08-12 |
Gpi Nil Holdings Inc. |
N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders
|
DE19918725A1
(de)
|
1999-04-24 |
2000-10-26 |
Bayer Ag |
Substituierte N-Cyano-sulfonsäureanilide
|
DE19929348A1
(de)
|
1999-06-26 |
2000-12-28 |
Bayer Ag |
Verfahren zur Herstellung von 2-Heterocyclylmethyl-benzoesäurederivaten
|
US7256005B2
(en)
|
1999-08-10 |
2007-08-14 |
The Chancellor, Masters And Scholars Of The University Of Oxford |
Methods for identifying iminosugar derivatives that inhibit HCV p7 ion channel activity
|
JP2003507424A
(ja)
|
1999-08-26 |
2003-02-25 |
ブリストル−マイヤーズ スクイブ カンパニー |
Npyアンタゴニスト:スピロイソキノリノン誘導体
|
IL150033A0
(en)
|
1999-12-17 |
2002-12-01 |
Schering Corp |
Selective neurokinin antagonists
|
US6436928B1
(en)
|
1999-12-17 |
2002-08-20 |
Schering Corporation |
Selective neurokinin antagonists
|
WO2001055063A1
(fr)
|
2000-01-25 |
2001-08-02 |
Idemitsu Petrochemical Co., Ltd. |
Nouveaux composes a base de bisadamantane, procedes de production et nouveaux derives de bisadamantane
|
GB0003397D0
(en)
|
2000-02-14 |
2000-04-05 |
Merck Sharp & Dohme |
Therapeutic agents
|
DE60114413T2
(de)
*
|
2000-05-25 |
2006-07-27 |
F. Hoffmann-La Roche Ag |
Substituierte 1-aminoalkyl-lactame und deren verwendung als muscarinrezeptor-antagonisten
|
DE10034623A1
(de)
|
2000-07-17 |
2002-01-31 |
Bayer Ag |
Heterocyclisch substituierte Pyridine als Cytokin-Inhibitoren
|
DE10034803A1
(de)
|
2000-07-18 |
2002-01-31 |
Bayer Ag |
Substituierte Sulfonsäureanilide
|
DE10034800A1
(de)
|
2000-07-18 |
2002-01-31 |
Bayer Ag |
Substituierte Benzostickstoffheterocyclen
|
DE10035927A1
(de)
|
2000-07-21 |
2002-03-07 |
Asta Medica Ag |
Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
|
DE10035908A1
(de)
|
2000-07-21 |
2002-03-07 |
Asta Medica Ag |
Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
|
DE10035928A1
(de)
|
2000-07-21 |
2002-03-07 |
Asta Medica Ag |
Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
|
BR0113300A
(pt)
|
2000-08-16 |
2004-01-13 |
Neurogen Corp |
Composto ou um sal deste farmaceuticamente aceitável, composição farmacêutica, método para o tratamento de uma doença ou distúrbio associados com o agonismo patogênico, agonismo inverso ou antagonismo do receptor de gabaa, uso de um composto ou um sal, é, métodos para localização dos receptores de gabaa em uma amostra de tecido, de inibição da ligação de um composto de benzodiazepina a um receptor de gabaa, e para a alteração da atividade de transdutora de sinal dos receptores de gabaa
|
JP2004509103A
(ja)
|
2000-09-11 |
2004-03-25 |
セプレイコー インコーポレイテッド |
モノアミン受容体及び輸送体のリガンドならびにその使用方法
|
US7294637B2
(en)
|
2000-09-11 |
2007-11-13 |
Sepracor, Inc. |
Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
|
JP2002179572A
(ja)
|
2000-10-06 |
2002-06-26 |
Nikken Chem Co Ltd |
アレルギー性眼疾患治療剤
|
US6841671B2
(en)
|
2000-10-26 |
2005-01-11 |
Pfizer Inc. |
Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors
|
US20030143668A1
(en)
|
2001-06-18 |
2003-07-31 |
National Institute Of Advanced Industrial |
Guanosine triphosphate-binding protein coupled receptors
|
JP3873115B2
(ja)
|
2001-09-25 |
2007-01-24 |
独立行政法人産業技術総合研究所 |
環状ウレタン製造方法
|
KR100687954B1
(ko)
|
2001-10-15 |
2007-02-27 |
쉐링 코포레이션 |
아데노신 A2a 수용체 길항제로서의이미다조(4,3-e)-1,2,4-트리아졸로(1,5-c) 피리미딘
|
AU2002349432A1
(en)
|
2001-11-22 |
2003-06-10 |
Ono Pharmaceutical Co., Ltd. |
Piperidin-2-one derivative compounds and drugs containing these compounds as the active ingredient
|
JP2005516964A
(ja)
|
2001-12-28 |
2005-06-09 |
バイエル・フアーマシユーチカルズ・コーポレーシヨン |
5−ht2cレセプターと関連する疾患における使用のための1h−ピラゾリル誘導体化合物
|
JP2003300884A
(ja)
|
2002-04-08 |
2003-10-21 |
Nikken Chem Co Ltd |
TNF−α産生阻害剤
|
CA2480092A1
(en)
|
2002-04-26 |
2003-11-06 |
Pfizer Products Inc. |
N-substituted-heteroaryloxy-aryl-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors
|
BR0309281A
(pt)
|
2002-04-26 |
2005-02-22 |
Pfizer Prod Inc |
Triaril-oxi-espiro-pirimidino-2,4,6-trionas inibidoras de metaloproteinases
|
AU2003229953A1
(en)
|
2002-04-30 |
2003-11-17 |
Kudos Pharmaceuticals Limited |
Phthalazinone derivatives
|
CA2486157C
(en)
|
2002-05-17 |
2013-04-16 |
Jenken Biosciences, Inc. |
Opioid and opioid-like compounds and uses thereof
|
ATE358482T1
(de)
|
2002-07-03 |
2007-04-15 |
Schering Corp |
1-amido-4-phenyl-4-benzyloxymethyl-piperidin derivative und verwandte verbindungen als neurokinin-1 (nk-1) antagonsisten zur behandlung von erbrechen, depressionen, angstzustände und husten
|
AU2003249812A1
(en)
|
2002-07-18 |
2004-02-09 |
Queen's University At Kingston |
Dihydrouracil compounds as anti-ictogenic or anti-epileptogenic agents
|
GB0218630D0
(en)
|
2002-08-10 |
2002-09-18 |
Tanabe Seiyaku Co |
Novel compounds
|
AR041198A1
(es)
|
2002-10-11 |
2005-05-04 |
Otsuka Pharma Co Ltd |
Compuesto 2,3-dihidro-6-nitroimidazo[2,1-b] oxaxol, y composiciones farmaceuticas que lo contienen
|
AU2003302027A1
(en)
|
2002-11-21 |
2004-06-15 |
Vicore Pharma Ab |
New tricyclic angiotensin ii agonists
|
GB0228410D0
(en)
|
2002-12-05 |
2003-01-08 |
Glaxo Group Ltd |
Novel Compounds
|
WO2004055008A1
(en)
|
2002-12-13 |
2004-07-01 |
Smithkline Beecham Corporation |
Compounds, compositions and methods
|
WO2004056744A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
|
DE602004028228D1
(de)
|
2003-03-26 |
2010-09-02 |
Merck Sharp & Dohme |
Bicyclische piperidin-derivate als melanocortin-4 rezeptor-agonisten
|
JP4629657B2
(ja)
|
2003-04-11 |
2011-02-09 |
ハイ・ポイント・ファーマスーティカルズ、エルエルシー |
11β−ヒドロキシステロイドデヒドロゲナーゼ1型化活性化合物
|
US7700583B2
(en)
|
2003-04-11 |
2010-04-20 |
High Point Pharmaceuticals, Llc |
11β-hydroxysteroid dehydrogenase type 1 active compounds
|
BRPI0410235A
(pt)
|
2003-04-16 |
2006-05-09 |
Memory Pharm Corp |
inibição de pde4, composto, composição farmacêutica, método para efetuar a inibição da enzima pde4, incrementar a cognição e/ou tratar a psicose em um paciente, método para o tratamento de um paciente que tem uma doença que envolve nìveis de camp diminuìdos, método para o tratamento de um paciente que sofre de uma doença alérgica ou inflamatória e método para o tratamento de um paciente que sofre de neurodegeneração resultante de uma doença ou de um ferimento
|
ITMI20031292A1
(it)
|
2003-06-25 |
2004-12-26 |
Nikem Research Srl |
Derivati biciclici nk-2 antagonisti selettivi.
|
DE10358004A1
(de)
|
2003-12-11 |
2005-07-14 |
Abbott Gmbh & Co. Kg |
Ketolactam-Verbindungen und ihre Verwendung
|
US7186844B2
(en)
|
2004-01-13 |
2007-03-06 |
Mitsubishi Gas Chemical Co., Inc. |
Method for producing cyclic carbamate ester
|
JP4324669B2
(ja)
|
2004-01-21 |
2009-09-02 |
独立行政法人産業技術総合研究所 |
環状ウレタンの製造方法
|
JP2005239670A
(ja)
|
2004-02-27 |
2005-09-08 |
Ono Pharmaceut Co Ltd |
含窒素複素環化合物およびその医薬用途
|
US7619086B2
(en)
|
2004-03-09 |
2009-11-17 |
Merck & Co., Inc. |
HIV integrase inhibitors
|
US8519158B2
(en)
|
2004-03-12 |
2013-08-27 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
JP2005272321A
(ja)
|
2004-03-23 |
2005-10-06 |
Ono Pharmaceut Co Ltd |
含窒素複素環化合物およびその医薬用途
|
NZ551077A
(en)
*
|
2004-05-07 |
2009-05-31 |
Janssen Pharmaceutica Nv |
Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
NZ551076A
(en)
|
2004-05-07 |
2009-05-31 |
Janssen Pharmaceutica Nv |
Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
GB0411404D0
(en)
|
2004-05-21 |
2004-06-23 |
Glaxo Group Ltd |
Novel compounds
|
BRPI0510394A
(pt)
|
2004-05-24 |
2007-11-13 |
Amgen Inc |
inibidores de 11-beta-hidroxiesteróide desidrogenase tipo 1
|
EA200700118A1
(ru)
|
2004-06-24 |
2007-08-31 |
Инсайт Корпорейшн |
Амидосоединения и их применение в качестве лекарственных средств
|
GB0414438D0
(en)
|
2004-06-28 |
2004-07-28 |
Syngenta Participations Ag |
Chemical compounds
|
DOP2005000123A
(es)
|
2004-07-02 |
2011-07-15 |
Merck Sharp & Dohme |
Inhibidores de cetp
|
EP1621536A1
(en)
|
2004-07-27 |
2006-02-01 |
Aventis Pharma S.A. |
Amino cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
|
EP1621535A1
(en)
|
2004-07-27 |
2006-02-01 |
Aventis Pharma S.A. |
Substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
|
EP1621539A1
(en)
|
2004-07-27 |
2006-02-01 |
Aventis Pharma S.A. |
Heterocycle -substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
|
AR050365A1
(es)
|
2004-08-02 |
2006-10-18 |
Osi Pharm Inc |
Compuestos inhibidores de multi- quinasa pirrolopirimidina aril- amino sustituidos.
|
CN101080226A
(zh)
*
|
2004-08-10 |
2007-11-28 |
因塞特公司 |
酰氨基化合物及它们作为药物的用途
|
CN101217958A
(zh)
|
2004-08-23 |
2008-07-09 |
默克公司 |
Akt活性抑制剂
|
ATE445600T1
(de)
|
2004-08-30 |
2009-10-15 |
Janssen Pharmaceutica Nv |
Derivate von tricyclischem lactam als 11-beta- hydroxysteroid-dehydrogenase-inhibitoren
|
CA2576839C
(en)
|
2004-08-30 |
2013-07-02 |
Janssen Pharmaceutica N.V. |
N-2 adamantanyl-2-phenoxy-acetamide derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
|
AU2005285035B2
(en)
|
2004-09-10 |
2012-03-22 |
Janssen Pharmaceutica N.V. |
Novel imidazolidin-2-one derivatives as selective androgen receptor modulators (SARMS)
|
RU2383533C2
(ru)
*
|
2004-10-04 |
2010-03-10 |
Ф.Хоффманн-Ля Рош Аг |
Алкилированные производные пиридина в качестве ингибиторов 11-бета при диабете
|
WO2006040329A1
(en)
|
2004-10-12 |
2006-04-20 |
Novo Nordisk A/S |
1 ibeta- hydroxysteroid dehydrogenase type 1 active spiro compounds
|
JP2008515972A
(ja)
|
2004-10-13 |
2008-05-15 |
ニューロジェン・コーポレーション |
メラニン濃縮ホルモン受容体のリガンドとしてのアリール置換8−アザビシクロ[3.2.1]オクタン化合物
|
ATE419848T1
(de)
|
2004-10-29 |
2009-01-15 |
Lilly Co Eli |
Cycloalkyl-lactam-derivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1
|
MX2007005527A
(es)
|
2004-11-10 |
2007-07-09 |
Incyte Corp |
Compuestos de lactama y sus usos como farmaceuticos.
|
GT200500375A
(es)
|
2004-12-20 |
2006-11-28 |
|
Derivados de piperidina y su uso como agentes antiinflamatorios
|
EP1828163A2
(en)
|
2004-12-23 |
2007-09-05 |
CHIESI FARMACEUTICI S.p.A. |
Azole derivatives with antimuscarinic activity
|
ATE543821T1
(de)
|
2004-12-28 |
2012-02-15 |
Exelixis Inc |
Ä1h-pyrazoloä3,4-düpyrimidin-4-ylü-piperidin- oder piperazinverbindungen als serin-threonin- kinasemodulatoren (p70s6k, atk1 und atk2) zur behandlung von immunologischen, entzündlichen und proliferativen erkrankungen
|
CN101107245A
(zh)
|
2005-01-19 |
2008-01-16 |
神经能质公司 |
经杂芳基取代的哌嗪-吡啶类似物
|
AU2006214477A1
(en)
|
2005-02-16 |
2006-08-24 |
Pharmacopeia, Inc. |
Heterocyclic substituted piperazines with CXCR3 antagonist activity
|
EP1858895B1
(en)
|
2005-02-16 |
2012-06-20 |
Schering Corporation |
Piperazine-piperidines with cxcr3 antagonist activity
|
MX2007009947A
(es)
|
2005-02-16 |
2007-09-26 |
Schering Corp |
Piperazin-piperidinas sustituidas con pirazinilo con actividad antagonista de cxcr3.
|
ATE523506T1
(de)
|
2005-02-16 |
2011-09-15 |
Schering Corp |
Amingebundene pyridyl- und phenylsubstituierte piperazin-piperidine mit cxcr3-antagonistischer aktivität
|
WO2006088840A1
(en)
|
2005-02-16 |
2006-08-24 |
Schering Corporation |
Novel heterocyclic substituted pyridine or phenyl compounds with cxcr3 antagonist activity
|
CA2598457A1
(en)
|
2005-02-16 |
2006-08-24 |
Schering Corporation |
Pyridyl and phenyl substituted piperazine-piperidines with cxcr3 antagonist activity
|
KR100890886B1
(ko)
|
2005-02-24 |
2009-03-31 |
니혼노야쿠가부시키가이샤 |
신규 할로알킬설폰아닐리드 유도체, 제초제 및 이의 이용방법
|
JPWO2006104280A1
(ja)
|
2005-03-31 |
2008-09-11 |
武田薬品工業株式会社 |
糖尿病の予防・治療剤
|
AU2006235706B2
(en)
|
2005-04-12 |
2012-03-08 |
Vicore Pharma Ab |
New tricyclic angiotensin II agonists
|
WO2007008529A2
(en)
|
2005-07-08 |
2007-01-18 |
Kalypsys, Inc |
Celullar cholesterol absorption modifiers
|
CA2619881A1
(en)
|
2005-08-16 |
2007-02-22 |
Genzyme Corporation |
Chemokine receptor binding compounds
|
ATE546445T1
(de)
|
2005-10-11 |
2012-03-15 |
Schering Corp |
Substituierte heterocyclische verbindungen mit cxcr3-antagonistischer wirkung
|
US7943605B2
(en)
|
2005-10-27 |
2011-05-17 |
Ucb Pharma S.A. |
Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
|
WO2007051810A2
(en)
|
2005-11-01 |
2007-05-10 |
Transtech Pharma |
Pharmaceutical use of substituted amides
|
JP2007140188A
(ja)
|
2005-11-18 |
2007-06-07 |
Fujifilm Corp |
ポジ型感光性組成物及びそれを用いたパターン形成方法
|
US8541592B2
(en)
|
2005-11-22 |
2013-09-24 |
Amgen Inc. |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1
|
US8193207B2
(en)
|
2005-12-05 |
2012-06-05 |
Incyte Corporation |
Lactam compounds and methods of using the same
|
EP1801098A1
(en)
|
2005-12-16 |
2007-06-27 |
Merck Sante |
2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors
|
WO2007076055A2
(en)
|
2005-12-22 |
2007-07-05 |
Entremed, Inc. |
Compositions and methods comprising proteinase activated receptor antagonists
|
DE102005062990A1
(de)
|
2005-12-28 |
2007-07-05 |
Grünenthal GmbH |
Substituierte Thiazole und ihre Verwendung zur Herstellung von Arzneimitteln
|
EP1973546B1
(en)
|
2005-12-30 |
2012-06-13 |
Merck Sharp & Dohme Corp. |
Cholesteryl ester transfer protein inhibitors
|
AU2006335108B2
(en)
|
2005-12-30 |
2011-04-07 |
Merck Sharp & Dohme Corp. |
CETP inhibitors
|
WO2007081571A2
(en)
|
2005-12-30 |
2007-07-19 |
Merck & Co., Inc. |
Cetp inhibitors
|
NZ568904A
(en)
|
2005-12-30 |
2011-05-27 |
Merck Sharp & Dohme |
1,3-oxazolidin-2-one derivatives useful as CETP inhibitors
|
US7998959B2
(en)
|
2006-01-12 |
2011-08-16 |
Incyte Corporation |
Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
CA2643163C
(en)
|
2006-02-27 |
2020-01-28 |
Bayer Healthcare Llc |
Temperature-adjusted analyte determination for biosensor systems
|
TW200808807A
(en)
|
2006-03-02 |
2008-02-16 |
Incyte Corp |
Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
WO2007103719A2
(en)
|
2006-03-03 |
2007-09-13 |
Incyte Corporation |
MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
|
WO2007109456A2
(en)
|
2006-03-16 |
2007-09-27 |
Pharmacopeia, Inc. |
Substituted biphenyl isoxazole sulfonamides as dual angiotensin endothelin receptor antagonists
|
JP2007254409A
(ja)
|
2006-03-24 |
2007-10-04 |
Taisho Pharmaceut Co Ltd |
イミダゾリジノン誘導体
|
US7435833B2
(en)
|
2006-04-07 |
2008-10-14 |
Abbott Laboratories |
Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
|
WO2007123853A2
(en)
|
2006-04-20 |
2007-11-01 |
E. I. Du Pont De Nemours And Company |
Five-membered heterocyclic invertebrate pest control agents
|
EA014717B1
(ru)
|
2006-04-21 |
2011-02-28 |
Эли Лилли Энд Компани |
ПРОИЗВОДНЫЕ ЛАКТАМА ЦИКЛОГЕКСИЛИМИДАЗОЛА В КАЧЕСТВЕ ИНГИБИТОРОВ 11-β-ГИДРОКСИСТЕРОИД ДЕГИДРОГЕНАЗЫ 1
|
ES2435115T3
(es)
|
2006-04-21 |
2013-12-18 |
Eli Lilly And Company |
Derivados de bifenilamida-lactama como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1
|
KR101055576B1
(ko)
|
2006-04-21 |
2011-08-08 |
일라이 릴리 앤드 캄파니 |
11-베타-히드록시스테로이드 데히드로게나제 1의 억제제로서의 시클로헥실피라졸-락탐 유도체
|
JP5189078B2
(ja)
*
|
2006-04-24 |
2013-04-24 |
イーライ リリー アンド カンパニー |
11−β−ヒドロキシステロイドデヒドロゲナーゼ1の阻害剤
|
US7968585B2
(en)
|
2006-04-25 |
2011-06-28 |
Eli Lilly And Company |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
US8178005B2
(en)
|
2006-06-20 |
2012-05-15 |
Chemtura Corporation |
Liquid phosphite compositions having different alkyl groups
|
TW200811170A
(en)
|
2006-06-27 |
2008-03-01 |
Sanofi Aventis |
Urea derivatives of tropane, their preparation and their therapeutic application
|
WO2008012622A2
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Azabenzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
WO2008012623A1
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Benzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
US7618989B2
(en)
*
|
2006-08-15 |
2009-11-17 |
Wyeth |
Tricyclic oxazolidone derivatives useful as PR modulators
|
US7649007B2
(en)
*
|
2006-08-15 |
2010-01-19 |
Wyeth Llc |
Oxazolidine derivatives as PR modulators
|
US7538107B2
(en)
*
|
2006-08-15 |
2009-05-26 |
Wyeth |
Oxazinan-2-one derivatives useful as PR modulators
|
US8927715B2
(en)
|
2006-08-25 |
2015-01-06 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11β-hydroxysteroid dehydrogenase type 1
|
CA2663280A1
(en)
|
2006-09-14 |
2008-03-20 |
Neuromed Pharmaceuticals Ltd. |
Diaryl piperidine compounds as calcium channel blockers
|
CN101516877B
(zh)
|
2006-09-22 |
2013-09-11 |
诺瓦提斯公司 |
杂环有机化合物
|
DE102007005799B4
(de)
|
2006-10-18 |
2018-01-25 |
Heinz-Jürgen Mühlen |
Verfahren zur Erzeugung eines wasserstoffreichen Produktgases
|
AU2007312391B2
(en)
*
|
2006-10-19 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Imidazolone and imidazolidinone derivatives as 11b-HSD1 inhibitors for diabetes
|
TW200829171A
(en)
|
2006-11-17 |
2008-07-16 |
Nihon Nohyaku Co Ltd |
Haloalkyl sulfonanilide derivatives or salts thereof, herbicide using it as effective constituent and use-method thereof
|
EP1935420A1
(en)
|
2006-12-21 |
2008-06-25 |
Merck Sante |
2-Adamantyl-butyramide derivatives as selective 11beta-HSD1 inhibitors
|
CA2678577A1
(en)
*
|
2007-02-26 |
2008-09-04 |
Vitae Pharmaceuticals, Inc. |
Cyclic urea and carbamate inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
|
JP2010522174A
(ja)
|
2007-03-23 |
2010-07-01 |
シェーリング コーポレイション |
Hcvns3−プロテアーゼ阻害剤としてのヒドラジド−ペプチド
|
WO2008119663A1
(en)
*
|
2007-03-29 |
2008-10-09 |
F. Hoffmann-La Roche Ag |
Heterocyclic antiviral compounds
|
CA2697168A1
(en)
|
2007-07-26 |
2009-02-05 |
Vitae Pharmaceuticals, Inc. |
Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
|
WO2009020140A1
(ja)
|
2007-08-06 |
2009-02-12 |
Dainippon Sumitomo Pharma Co., Ltd. |
アダマンチルウレア誘導体
|
JP2009110842A
(ja)
|
2007-10-31 |
2009-05-21 |
Sumitomo Chemical Co Ltd |
ボタンスイッチ被覆用積層樹脂体
|
AR069207A1
(es)
|
2007-11-07 |
2010-01-06 |
Vitae Pharmaceuticals Inc |
Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
|
JP5769970B2
(ja)
|
2007-11-16 |
2015-08-26 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
|
US8440658B2
(en)
|
2007-12-11 |
2013-05-14 |
Vitae Pharmaceuticals, Inc. |
Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
KR101460359B1
(ko)
|
2007-12-13 |
2014-11-10 |
삼성전자주식회사 |
이동통신 시스템에서의 핸드오버 방법 및 장치
|
TW200934490A
(en)
|
2008-01-07 |
2009-08-16 |
Vitae Pharmaceuticals Inc |
Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
|
JP5490020B2
(ja)
|
2008-01-24 |
2014-05-14 |
ヴァイティー ファーマシューティカルズ,インコーポレイテッド |
11β−ヒドロキシステロイドデヒドロゲナーゼ1の環状カルバゼート及びセミカルバジドインヒビター
|
CA2714532A1
(en)
|
2008-02-11 |
2009-08-20 |
Vitae Pharmaceuticals, Inc. |
1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
|
ATE531696T1
(de)
|
2008-02-12 |
2011-11-15 |
Boehringer Ingelheim Int |
Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung
|
US8598160B2
(en)
|
2008-02-15 |
2013-12-03 |
Vitae Pharmaceuticals, Inc. |
Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
|
JP5108557B2
(ja)
|
2008-02-27 |
2012-12-26 |
東京エレクトロン株式会社 |
ロードロック装置および基板冷却方法
|
CA2716128A1
(en)
|
2008-02-27 |
2009-09-03 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11.beta.-hydroxysteroid dehydrogenase type 1
|
CA2718264A1
(en)
|
2008-03-18 |
2009-09-24 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
|
TW200944526A
(en)
|
2008-04-22 |
2009-11-01 |
Vitae Pharmaceuticals Inc |
Carbamate and urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
AU2009241727B2
(en)
|
2008-05-01 |
2013-05-02 |
Vitae Pharmaceuticals, Inc |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
US8242111B2
(en)
|
2008-05-01 |
2012-08-14 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
|
EP2291370B1
(en)
|
2008-05-01 |
2013-11-27 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
EP2291371B1
(en)
|
2008-05-01 |
2015-06-10 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
TW200950780A
(en)
|
2008-05-13 |
2009-12-16 |
Boehringer Ingelheim Int |
Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
|
US20110224242A1
(en)
|
2008-07-23 |
2011-09-15 |
Bioalliance Pharma |
Styrlyquinolines, their process of preparation and their therapeutic uses
|
WO2010010149A1
(en)
|
2008-07-23 |
2010-01-28 |
Bioalliance Pharma |
Styrylquinolines, their process of preparation and their therapeutic uses
|
US8309597B2
(en)
|
2008-07-25 |
2012-11-13 |
Boehringer Ingelheim International Gmbh |
1,1′-diadamantyl carboxylic acids, medicaments containing such compounds and their use
|
KR20110050459A
(ko)
|
2008-07-25 |
2011-05-13 |
비타이 파마슈티컬즈, 인코포레이티드 |
11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
|
TW201016691A
(en)
|
2008-07-25 |
2010-05-01 |
Boehringer Ingelheim Int |
Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
US8487094B2
(en)
|
2008-07-25 |
2013-07-16 |
Boehringer Ingelheim International Gmbh |
Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1
|
EP2318403B1
(en)
|
2008-08-25 |
2015-12-23 |
Boehringer Ingelheim International GmbH |
Aryl- and heteroarylcarbonyl derivatives of substituted nortropanes, medicaments containing such compounds and their use
|
TW201022266A
(en)
|
2008-10-23 |
2010-06-16 |
Boehringer Ingelheim Int |
Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use
|
WO2010091067A2
(en)
|
2009-02-04 |
2010-08-12 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
EP2393807B1
(en)
|
2009-02-04 |
2013-08-14 |
Boehringer Ingelheim International GmbH |
Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1
|
WO2010104830A1
(en)
|
2009-03-09 |
2010-09-16 |
Bristol-Myers Squibb Company |
Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
|
US20100331320A1
(en)
|
2009-04-30 |
2010-12-30 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
US8680093B2
(en)
|
2009-04-30 |
2014-03-25 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
AR076936A1
(es)
|
2009-06-02 |
2011-07-20 |
Vitae Pharmaceuticals Inc |
Inhibidores de carbamato y urea de la 11 beta hidroxiesteroide deshidrogenasa 1
|
WO2010139673A1
(en)
|
2009-06-02 |
2010-12-09 |
Boehringer Ingelheim International Gmbh |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
US8927539B2
(en)
|
2009-06-11 |
2015-01-06 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
|
WO2011002910A1
(en)
|
2009-07-01 |
2011-01-06 |
Vitae Pharmaceuticals, Inc. |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
SG179083A1
(en)
|
2009-09-11 |
2012-04-27 |
Cylene Pharmaceuticals Inc |
Pharmaceutically useful heterocycle-substituted lactams
|
JP5750449B2
(ja)
|
2009-11-05 |
2015-07-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
新規キラルリンリガンド
|
UY33001A
(es)
|
2009-11-06 |
2011-05-31 |
Boehringer Ingelheim Int |
Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
|
US8933072B2
(en)
|
2010-06-16 |
2015-01-13 |
Vitae Pharmaceuticals, Inc. |
Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
|
WO2011161128A1
(en)
|
2010-06-25 |
2011-12-29 |
Boehringer Ingelheim International Gmbh |
Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
|
CA2813671A1
(en)
|
2010-11-02 |
2012-05-10 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical combinations for the treatment of metabolic disorders
|