CO4970829A1 - Polimorfo antifungico cristalino - Google Patents
Polimorfo antifungico cristalinoInfo
- Publication number
- CO4970829A1 CO4970829A1 CO98057733A CO98057733A CO4970829A1 CO 4970829 A1 CO4970829 A1 CO 4970829A1 CO 98057733 A CO98057733 A CO 98057733A CO 98057733 A CO98057733 A CO 98057733A CO 4970829 A1 CO4970829 A1 CO 4970829A1
- Authority
- CO
- Colombia
- Prior art keywords
- antifungal
- crystalline polymorph
- polymorph
- triazol
- phenyl
- Prior art date
Links
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 title 1
- -1 1H- 1,2,4-triazol-1-ylmethyl Chemical group 0.000 abstract 1
- 125000004215 2,4-difluorophenyl group Chemical group [H]C1=C([H])C(*)=C(F)C([H])=C1F 0.000 abstract 1
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- STTHYLJITRSSSN-JQWIXIFHSA-N C1(=CC=CC=C1)N1C(N(N=C1)[C@H]([C@H](C)O)CC)=O Chemical compound C1(=CC=CC=C1)N1C(N(N=C1)[C@H]([C@H](C)O)CC)=O STTHYLJITRSSSN-JQWIXIFHSA-N 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94618397A | 1997-10-07 | 1997-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4970829A1 true CO4970829A1 (es) | 2000-11-07 |
Family
ID=25484068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO98057733A CO4970829A1 (es) | 1997-10-07 | 1998-10-05 | Polimorfo antifungico cristalino |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1021439B1 (enEXAMPLES) |
| JP (4) | JP2001519346A (enEXAMPLES) |
| KR (1) | KR100626109B1 (enEXAMPLES) |
| CN (1) | CN1125067C (enEXAMPLES) |
| AR (1) | AR015947A1 (enEXAMPLES) |
| AT (1) | ATE263163T1 (enEXAMPLES) |
| AU (1) | AU759982B2 (enEXAMPLES) |
| BR (1) | BR9812866A (enEXAMPLES) |
| CA (1) | CA2305803C (enEXAMPLES) |
| CO (1) | CO4970829A1 (enEXAMPLES) |
| CZ (1) | CZ299835B6 (enEXAMPLES) |
| DE (1) | DE69822859T2 (enEXAMPLES) |
| DK (1) | DK1021439T3 (enEXAMPLES) |
| ES (1) | ES2217594T3 (enEXAMPLES) |
| HU (1) | HU225233B1 (enEXAMPLES) |
| ID (1) | ID29290A (enEXAMPLES) |
| IL (1) | IL135331A (enEXAMPLES) |
| IN (1) | IN1998CH02232A (enEXAMPLES) |
| MX (1) | MX225999B (enEXAMPLES) |
| MY (1) | MY130126A (enEXAMPLES) |
| NO (1) | NO318827B1 (enEXAMPLES) |
| NZ (1) | NZ503662A (enEXAMPLES) |
| PE (1) | PE120499A1 (enEXAMPLES) |
| PH (1) | PH11998002606B1 (enEXAMPLES) |
| PL (1) | PL189317B1 (enEXAMPLES) |
| PT (1) | PT1021439E (enEXAMPLES) |
| SK (1) | SK285190B6 (enEXAMPLES) |
| TW (1) | TW589310B (enEXAMPLES) |
| WO (1) | WO1999018097A1 (enEXAMPLES) |
| ZA (1) | ZA989063B (enEXAMPLES) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2130540A1 (en) * | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) * | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| US20120101277A1 (en) | 2009-07-09 | 2012-04-26 | Sandoz Ag | Crystalline form of posaconazole |
| RU2585683C2 (ru) | 2010-05-19 | 2016-06-10 | Сандоз Аг | Очистка позаконазола и промежуточных продуктов для синтеза позаконазола |
| JP5956980B2 (ja) | 2010-05-19 | 2016-07-27 | サンド・アクチエンゲゼルシヤフト | キラル化合物の調製の方法 |
| JP6013326B2 (ja) * | 2010-05-19 | 2016-10-25 | サンド・アクチエンゲゼルシヤフト | キラルトリアゾロンの調製のための方法 |
| WO2011144656A1 (en) | 2010-05-19 | 2011-11-24 | Sandoz Ag | Preparation of posaconazole intermediates |
| WO2012172015A1 (en) | 2011-06-16 | 2012-12-20 | Sandoz Ag | Process for the preparation of a chiral compound |
| WO2013042138A2 (en) | 2011-09-19 | 2013-03-28 | Msn Laboratories Limited | Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof |
| WO2015011224A1 (en) * | 2013-07-25 | 2015-01-29 | Sandoz Ag | Improved process for the preparation of crystalline form iv of posaconazole |
| ITMI20132118A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132117A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132114A1 (it) | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132115A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| CN104387374A (zh) * | 2014-10-21 | 2015-03-04 | 江苏恒盛药业有限公司 | 泊沙康唑晶型i的制备工艺 |
| CN104370894A (zh) * | 2014-10-21 | 2015-02-25 | 江苏恒盛药业有限公司 | 无定型泊沙康唑的制备工艺 |
| CA2965169C (en) | 2014-10-21 | 2021-11-16 | Ariad Pharmaceuticals, Inc. | Crystalline forms of 5-chloro-n4-[2-(dimethylphosphoryl)phenyl]-n2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrimidine-2,4-diamine |
| US11058682B2 (en) | 2015-08-08 | 2021-07-13 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant formulation containing posaconazole |
| AU2016375899B2 (en) | 2015-12-24 | 2021-05-13 | Takeda Pharmaceutical Company Limited | Cocrystal, production method thereof, and medicament containing cocrystal |
| EP3925601B1 (en) | 2016-02-26 | 2024-07-17 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor |
| CN105949278B (zh) * | 2016-03-30 | 2019-12-06 | 南京曼杰生物科技有限公司 | 一种取代的四氢呋喃水溶性衍生物及其应用 |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| TR201620462A2 (tr) | 2016-12-31 | 2018-07-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ |
| TR201722493A2 (tr) | 2017-12-28 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Posakonazol i̇çeren kati farmasöti̇k kompozi̇syon |
| US20240293399A1 (en) | 2020-08-13 | 2024-09-05 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant high-strength formulation containing posaconazole |
| WO2023012378A1 (en) | 2021-11-25 | 2023-02-09 | Alfred E. Tiefenbacher (Gmbh Und Co. Kg) | Granules containing posaconazole |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL103558A0 (en) * | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
| PL181193B1 (pl) * | 1993-12-21 | 2001-06-29 | Schering Corp | Nowe pochodne tetrahydrofuranowe o działaniu przeciwgrzybicznym, kompozycja farmaceutyczna do leczenia infekcji grzybiczych oraz sposób wytwarzania tych związków |
| CN1078210C (zh) * | 1994-01-24 | 2002-01-23 | 詹森药业有限公司 | 水溶性吡咯系杀真菌剂 |
| US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| AR002751A1 (es) * | 1995-06-02 | 1998-04-29 | Schering Corp | Antifungicos de tetrahidrofurano, composiciones farmaceuticas que los contienen y el uso de los compuestos para preparar composiciones farmaceuticas utiles para el tratamiento de infecciones fungicas |
-
1998
- 1998-10-05 PE PE1998000942A patent/PE120499A1/es not_active IP Right Cessation
- 1998-10-05 ZA ZA989063A patent/ZA989063B/xx unknown
- 1998-10-05 JP JP2000514908A patent/JP2001519346A/ja not_active Withdrawn
- 1998-10-05 SK SK512-2000A patent/SK285190B6/sk not_active IP Right Cessation
- 1998-10-05 EP EP98951994A patent/EP1021439B1/en not_active Expired - Lifetime
- 1998-10-05 NZ NZ503662A patent/NZ503662A/xx not_active IP Right Cessation
- 1998-10-05 CA CA002305803A patent/CA2305803C/en not_active Expired - Lifetime
- 1998-10-05 DK DK98951994T patent/DK1021439T3/da active
- 1998-10-05 ID IDW20000632A patent/ID29290A/id unknown
- 1998-10-05 KR KR20007003709A patent/KR100626109B1/ko not_active Expired - Lifetime
- 1998-10-05 ES ES98951994T patent/ES2217594T3/es not_active Expired - Lifetime
- 1998-10-05 AT AT98951994T patent/ATE263163T1/de active
- 1998-10-05 AR ARP980104957A patent/AR015947A1/es not_active Application Discontinuation
- 1998-10-05 BR BR9812866-3A patent/BR9812866A/pt not_active Application Discontinuation
- 1998-10-05 PT PT98951994T patent/PT1021439E/pt unknown
- 1998-10-05 PL PL98339659A patent/PL189317B1/pl unknown
- 1998-10-05 WO PCT/US1998/020476 patent/WO1999018097A1/en active IP Right Grant
- 1998-10-05 DE DE69822859T patent/DE69822859T2/de not_active Expired - Lifetime
- 1998-10-05 CO CO98057733A patent/CO4970829A1/es unknown
- 1998-10-05 AU AU97803/98A patent/AU759982B2/en not_active Expired
- 1998-10-05 CZ CZ20001264A patent/CZ299835B6/cs not_active IP Right Cessation
- 1998-10-05 HU HU0004899A patent/HU225233B1/hu unknown
- 1998-10-05 IL IL13533198A patent/IL135331A/xx not_active IP Right Cessation
- 1998-10-05 CN CN98811886A patent/CN1125067C/zh not_active Expired - Lifetime
- 1998-10-06 TW TW087116562A patent/TW589310B/zh not_active IP Right Cessation
- 1998-10-06 IN IN2232CH1998 patent/IN1998CH02232A/en unknown
- 1998-10-06 MY MYPI98004576A patent/MY130126A/en unknown
- 1998-10-06 PH PH11998002606A patent/PH11998002606B1/en unknown
-
2000
- 2000-04-06 NO NO20001779A patent/NO318827B1/no not_active IP Right Cessation
- 2000-04-06 MX MXPA00003404 patent/MX225999B/es active IP Right Grant
-
2008
- 2008-01-04 JP JP2008000110A patent/JP2008106075A/ja not_active Withdrawn
-
2012
- 2012-05-18 JP JP2012114724A patent/JP2012153729A/ja active Pending
- 2012-05-18 JP JP2012114725A patent/JP2012153730A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO4970829A1 (es) | Polimorfo antifungico cristalino | |
| NO986087L (no) | Oralt preparat omfattende en antifungal triazolforbindelse | |
| KR920006323A (ko) | 아자사이클릭 화합물 | |
| NO1997006I1 (no) | Anastrozol/<alfa>,<alfa>,<alfa>',<alfa>'-tetrametyl-5(1H-1,2,4-triazol-1-ylmetyl)-m-benzendiatonitril | |
| KR910021398A (ko) | 트리아졸 항진균제 | |
| BR0007500A (pt) | Composto triazol, fármaco, e, uso do composto | |
| KR890006593A (ko) | 아르마타제 억제4(5)- 이미다졸 | |
| PE20110930A1 (es) | 3,5-bis(3,4-dihidroxifenil)-1,2,4-triazol y la composicion que lo comprende | |
| ES537182A0 (es) | Procedimiento de obtencion de compuestos de 1-aril-2-(3-(4-trifluormetilestiril)-1,2,4-triazol-1-il)-1-c 1,2,4,-triazol-1-il-metil) etanol de efecto antifugal. | |
| JP2001519346A5 (enEXAMPLES) | ||
| KR920008017A (ko) | 피페라진 유도체 | |
| KR920019781A (ko) | 벤즈이미다졸류로부터 유도된 항진정 항히스타민제 | |
| BR0008221A (pt) | Compostos heterocìclicos debenzenosulfonamidas como antagonistasbradykinina | |
| PE20000328A1 (es) | Azoles | |
| ZA794850B (en) | Halogenated loweralkenyl benzimidazoles | |
| PE20050950A1 (es) | Derivados de triazol sustituidos como antagonistas de oxitocina | |
| DE59200199D1 (de) | Fungizide Mischung. | |
| MY118988A (en) | Antifungal composition with enhanced bioavailability | |
| BRPI0610423B8 (pt) | sal de mono-lisina de di-hidrogênio fosfato de ((2r, 3r)-3-(4-(4-cianofenil)-tiazol-2-il)-2-(2,4-difluorofenil)-1-(1h-1,2,4-triazol-1-il)butan-2-iloxi)metila, solvatos do mesmo, composição farma-cêutica compreendendo os mesmos, uso do dito sal para tratar infecções fúngicas e processos para preparar ditos sal e sol- vato | |
| DE69026311D1 (de) | 4-[4-[4-[4-[[2-(2,4-Difluorphenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]triazolone und Imidazolone zur Bekämpfung von Pilzen | |
| DK24884D0 (da) | 1-heterocyclyl-2-phenyl-3-(1,2,4-triazol-1-yl)propan-2-ol-forbindelser og farmaceutisk acceptable salte deraf samt farmaceutisk praeparat indeholdende disse forbindelser | |
| BR0212536A (pt) | Inseticida de 3-(fenil 2,6-dissubstituìdo)-5-[4- ou 5-ariltien-2- ou -3-il]-1,2,4-triazóis | |
| BR0210701A (pt) | Derivados de halofenila intermediária e seu uso em um processo para a preparação de derivados de azol | |
| DE60205239D1 (de) | Azol- oder triazol-derivate, verfahren zu deren herstellung und ihre verwendung als antifungale arzneimittel | |
| AR043250A1 (es) | Derivados de triazol como agentes insecticidas y antihelminticos |