CN109803673A - 非蛋白质梭菌毒素组合物 - Google Patents

非蛋白质梭菌毒素组合物 Download PDF

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Publication number
CN109803673A
CN109803673A CN201780063116.1A CN201780063116A CN109803673A CN 109803673 A CN109803673 A CN 109803673A CN 201780063116 A CN201780063116 A CN 201780063116A CN 109803673 A CN109803673 A CN 109803673A
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CN
China
Prior art keywords
composition
trehalose
methionine
edta
sucrose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780063116.1A
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English (en)
Chinese (zh)
Inventor
M·阿比阿德
B·达尼
E·沙拉耶夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
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Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59974865&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN109803673(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Priority to CN202410133706.9A priority Critical patent/CN117959415A/zh
Publication of CN109803673A publication Critical patent/CN109803673A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
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    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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    • C—CHEMISTRY; METALLURGY
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
CN201780063116.1A 2016-09-13 2017-09-13 非蛋白质梭菌毒素组合物 Pending CN109803673A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410133706.9A CN117959415A (zh) 2016-09-13 2017-09-13 非蛋白质梭菌毒素组合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662394009P 2016-09-13 2016-09-13
US62/394,009 2016-09-13
PCT/US2017/051369 WO2018053004A2 (en) 2016-09-13 2017-09-13 Non-protein clostridial toxin compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202410133706.9A Division CN117959415A (zh) 2016-09-13 2017-09-13 非蛋白质梭菌毒素组合物

Publications (1)

Publication Number Publication Date
CN109803673A true CN109803673A (zh) 2019-05-24

Family

ID=59974865

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201780063116.1A Pending CN109803673A (zh) 2016-09-13 2017-09-13 非蛋白质梭菌毒素组合物
CN201780061279.6A Pending CN109803672A (zh) 2016-09-13 2017-09-13 稳定的非蛋白质梭菌毒素组合物
CN202410133706.9A Pending CN117959415A (zh) 2016-09-13 2017-09-13 非蛋白质梭菌毒素组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201780061279.6A Pending CN109803672A (zh) 2016-09-13 2017-09-13 稳定的非蛋白质梭菌毒素组合物
CN202410133706.9A Pending CN117959415A (zh) 2016-09-13 2017-09-13 非蛋白质梭菌毒素组合物

Country Status (28)

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US (10) US10369190B2 (enExample)
EP (4) EP3432916B1 (enExample)
JP (4) JP7217700B2 (enExample)
KR (6) KR102480965B1 (enExample)
CN (3) CN109803673A (enExample)
AU (4) AU2017327369A1 (enExample)
BR (2) BR112019004929A2 (enExample)
CA (2) CA3035473A1 (enExample)
CL (1) CL2019000586A1 (enExample)
CO (1) CO2019003630A2 (enExample)
CY (2) CY1122263T1 (enExample)
DK (2) DK3432916T3 (enExample)
ES (2) ES2755815T3 (enExample)
HR (1) HRP20191966T4 (enExample)
HU (2) HUE046449T2 (enExample)
IL (2) IL265109B2 (enExample)
LT (1) LT3436054T (enExample)
MX (2) MX2019002835A (enExample)
PH (1) PH12019500501A1 (enExample)
PL (2) PL3432916T3 (enExample)
PT (2) PT3436054T (enExample)
RS (1) RS59600B2 (enExample)
RU (2) RU2762607C2 (enExample)
SA (1) SA519401298B1 (enExample)
SI (2) SI3436054T2 (enExample)
SM (1) SMT201900625T1 (enExample)
TW (2) TWI773686B (enExample)
WO (2) WO2018053021A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118697853A (zh) * 2024-06-27 2024-09-27 河北封章生物科技有限公司 一种稳定性提高的肉毒素制剂

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
HUE046449T2 (hu) * 2016-09-13 2020-03-30 Allergan Inc Stabilizált, nem fehérje eredetû, clostridiális toxin készítmények
KR102646145B1 (ko) 2018-05-31 2024-03-11 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 모공 축소용 조성물
KR102058961B1 (ko) 2018-07-28 2019-12-24 주식회사 엑소코바이오 엑소좀의 동결건조 방법
KR102163806B1 (ko) 2018-07-30 2020-10-07 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물
US20200108129A1 (en) * 2018-09-13 2020-04-09 Allergan, Inc. Clostridial toxin - hyaluronic acid compositions
KR102259423B1 (ko) * 2018-11-30 2021-06-02 주식회사 휴온스바이오파마 보툴리눔 독소의 안정화 액상 조성물
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