CH624085A5 - - Google Patents

Download PDF

Info

Publication number
CH624085A5
CH624085A5 CH7780A CH7780A CH624085A5 CH 624085 A5 CH624085 A5 CH 624085A5 CH 7780 A CH7780 A CH 7780A CH 7780 A CH7780 A CH 7780A CH 624085 A5 CH624085 A5 CH 624085A5
Authority
CH
Switzerland
Prior art keywords
optically active
coch
viii
demethoxy
acid
Prior art date
Application number
CH7780A
Other languages
German (de)
English (en)
Inventor
Federico Arcamone
Luigi Bernardi
Bianca Patelli
Aurelio Di Marco
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of CH624085A5 publication Critical patent/CH624085A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH7780A 1975-01-22 1980-01-07 CH624085A5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2691/75A GB1500421A (en) 1975-01-22 1975-01-22 Optically active anthracyclinones

Publications (1)

Publication Number Publication Date
CH624085A5 true CH624085A5 (es) 1981-07-15

Family

ID=9744103

Family Applications (3)

Application Number Title Priority Date Filing Date
CH74276A CH622486A5 (es) 1975-01-22 1976-01-21
CH7880A CH622530A5 (es) 1975-01-22 1980-01-07
CH7780A CH624085A5 (es) 1975-01-22 1980-01-07

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH74276A CH622486A5 (es) 1975-01-22 1976-01-21
CH7880A CH622530A5 (es) 1975-01-22 1980-01-07

Country Status (18)

Country Link
US (1) US4077988A (es)
JP (4) JPS6033819B2 (es)
AT (1) AT342035B (es)
AU (1) AU500067B2 (es)
BE (1) BE837756A (es)
CA (1) CA1064920A (es)
CH (3) CH622486A5 (es)
DE (2) DE2601785C2 (es)
DK (1) DK155518C (es)
ES (1) ES444494A1 (es)
FR (4) FR2320105A1 (es)
GB (1) GB1500421A (es)
HK (1) HK1082A (es)
MX (1) MX4278E (es)
NL (1) NL179724C (es)
SE (4) SE435498B (es)
SU (5) SU683613A3 (es)
ZA (1) ZA76292B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318308A1 (de) * 1982-08-13 1984-02-16 Farmitalia Carlo Erba S.p.A., 20159 Milano Naphthacenchinon-derivate und verfahren zu ihrer herstellung

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070382A (en) * 1975-11-18 1978-01-24 Research Corporation Intermediates for polycyclic quinoid antibiotics
GB1527050A (en) * 1976-06-19 1978-10-04 Farmaceutici Italia Optically active anthracyclinones
US4134903A (en) * 1976-08-07 1979-01-16 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and their preparation
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
GB1573036A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
US4296105A (en) * 1978-08-03 1981-10-20 Institut International De Pathologie Cellulaire Et Moleculaire Derivatives of doxorubicine, their preparation and use
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
US4259476A (en) * 1979-04-02 1981-03-31 Kende Andrew S Novel heterocyclic anthracycline compounds
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
JPS5673039A (en) * 1979-08-20 1981-06-17 Hoffmann La Roche Naphthacene derivative
GB2071084B (en) * 1980-01-22 1984-02-29 Hoffmann La Roche Polycylic compounds
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
ES514486A0 (es) * 1981-07-29 1983-08-16 Sumitomo Chemical Co Un procedimiento para la preparacion de derivados de aminonaftaceno.
US4489206A (en) * 1983-05-13 1984-12-18 Adria Laboratories, Inc. Synthesis of (+)-4-demethoxydaunomycinone
US4831019A (en) * 1983-10-31 1989-05-16 Adria Laboratories, Inc. Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
AU622105B2 (en) * 1987-03-11 1992-04-02 Austin Research Institute, The Immunoglobulin conjugates
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8824947D0 (en) * 1988-10-25 1988-11-30 Erba Carlo Spa New 4-substituted anthracyclinones & process for preparing them
NL9001834A (nl) * 1990-08-16 1992-03-16 Pharmachemie Bv Nieuwe antracyclineverbindingen met anti-tumorwerkzaamheid, nieuwe tussenverbindingen voor de bereiding van deze antracyclineverbindingen, alsmede preparaten die de aktieve antracyclineverbindingen bevatten.
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
IT1317106B1 (it) * 2000-11-16 2003-05-26 Menarini Ricerche Spa Processo per la sintesi di antracicline otticamente attive.
DE10155016A1 (de) * 2001-11-07 2003-05-15 Knoell Hans Forschung Ev Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904632A (en) * 1972-05-08 1975-09-09 Hoffmann La Roche (')-di-o-isopropylidene-2-keto-l-gulonates
JPS5840556A (ja) * 1981-09-04 1983-03-09 Ricoh Co Ltd 電子写真圧力定着転写紙及びその転写紙用原紙の製造法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318308A1 (de) * 1982-08-13 1984-02-16 Farmitalia Carlo Erba S.p.A., 20159 Milano Naphthacenchinon-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DE2660848C2 (de) 1986-02-06
ZA76292B (en) 1977-01-26
SE461525B (sv) 1990-02-26
US4077988A (en) 1978-03-07
FR2320085B1 (es) 1978-11-03
JPS6033819B2 (ja) 1985-08-05
JPS5198264A (en) 1976-08-30
DK155518C (da) 1989-08-28
CH622530A5 (es) 1981-04-15
FR2320086A1 (fr) 1977-03-04
BE837756A (fr) 1976-07-22
SE461529B (sv) 1990-02-26
SU683613A3 (ru) 1979-08-30
SU646914A3 (ru) 1979-02-05
FR2320086B1 (es) 1978-11-03
JPS59231038A (ja) 1984-12-25
NL179724C (nl) 1986-11-03
FR2333769A1 (fr) 1977-07-01
SE8201013L (sv) 1982-02-18
SE435498B (sv) 1984-10-01
SE8201015L (sv) 1982-02-18
FR2320105A1 (fr) 1977-03-04
JPS59231098A (ja) 1984-12-25
MX4278E (es) 1982-03-11
FR2333769B1 (es) 1979-07-06
SE453185B (sv) 1988-01-18
AU500067B2 (en) 1979-05-10
ES444494A1 (es) 1977-05-16
CH622486A5 (es) 1981-04-15
DE2601785C2 (de) 1985-10-03
NL7600075A (nl) 1976-07-26
AT342035B (de) 1978-03-10
DE2601785A1 (de) 1976-07-29
ATA30676A (de) 1977-07-15
CA1064920A (en) 1979-10-23
HK1082A (en) 1982-01-22
FR2320105B1 (es) 1982-07-23
SE8201014L (sv) 1982-02-18
SU724087A3 (ru) 1980-03-25
JPH036157B2 (es) 1991-01-29
FR2320085A1 (fr) 1977-03-04
DK155518B (da) 1989-04-17
GB1500421A (en) 1978-02-08
NL179724B (nl) 1986-06-02
SU650498A3 (ru) 1979-02-28
JPS59231037A (ja) 1984-12-25
DK20376A (da) 1976-08-02
AU1043276A (en) 1977-07-28
SE7600563L (sv) 1976-07-23
SU776557A3 (ru) 1980-10-30

Similar Documents

Publication Publication Date Title
CH624085A5 (es)
DE2760005C2 (de) Optisch aktive Norpinene und Verfahren zu ihrer Herstellung
DE3219380C2 (de) Desmethoxy-anthracyclinglycoside, Verfahren zu deren Herstellung sowie pharmazeutische Mittel, die diese enthalten
EP0045837B1 (de) Reaktive Derivate des 3-Oxa-bicyclo(4.3.0)-non-1-en-9-ons, Verfahren zu ihrer Herstellung und deren Verwendung
CH630888A5 (de) Verfahren zur herstellung eines regioisomerengemisches von naphthacentetraonverbindungen.
EP0153615A1 (de) Verfahren zur Herstellung von Tetronsäure
DE2651773A1 (de) Neue derivate des daunorubicins, ihre herstellung und die sie enthaltenden zusammensetzungen
EP0053823B1 (de) Optisch reine Bicyclo(2.2.2)oct-5-en-2-one, Verfahren zu ihrer Herstellung und ihre Verwendung
AT343812B (de) Verfahren zur herstellung von neuen optisch aktiven daunosaminylderivaten von anthracyclinonen
AT343811B (de) Verfahren zur herstellung von neuen optisch aktiven anthracyclinonen
DE2453649B2 (de) Verfahren zur Herstellung von Coformycin und Zwischenprodukte zu seiner Herstellung
DE3014685A1 (de) Polycyclische verbindungen und verfahren zu deren herstellung
AT346838B (de) Verfahren zur herstellung von neuen optisch aktiven anthracyclinonen
DE2702807A1 (de) Verfahren zur herstellung von racemischem oder optisch aktivem 5beta- halogen-2beta-hydroxymethyl-cyclopentan-3alpha-hydroxy-1 alpha-essigsaeure (1' pfeil nach rechts 3) delta-lacton
DE2613701C2 (es)
CH646968A5 (de) 1,4-dioxaspiro(4,5)decen-verbindungen sowie verfahren zur herstellung von 2-hydroxy-3-substituierten propylarylaethern.
CH638487A5 (en) Novel substituted di(phenylethyl)amines
DE3100968A1 (de) Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2625671A1 (de) Verfahren zur herstellung von optisch aktiven indolochinolizinen
DE1958646B2 (de) In 4-SteUung substituierte 3,5-Dimethylisoxazole und deren Herstellung
DE3511716A1 (de) 6,6-aethylendioxy-22r-hydroxy-2r,3s-isopropylidendioxy-5(alpha)-cholest-23-in
CH639082A5 (de) Bicyclische lactol-methyl-aether und ein verfahren zu ihrer herstellung.
DE3101665A1 (de) Verfahren zur herstellung von tetrahydronaphthacenderivaten
DE3529794A1 (de) Anthracyclinglykoside
DE1906781A1 (de) Substituierte 3-Benzazocin-6-one und Verfahren zu ihrer Herstellung

Legal Events

Date Code Title Description
PL Patent ceased