ES8308301A1 - Un procedimiento para la preparacion de derivados de aminonaftaceno. - Google Patents
Un procedimiento para la preparacion de derivados de aminonaftaceno.Info
- Publication number
- ES8308301A1 ES8308301A1 ES514486A ES514486A ES8308301A1 ES 8308301 A1 ES8308301 A1 ES 8308301A1 ES 514486 A ES514486 A ES 514486A ES 514486 A ES514486 A ES 514486A ES 8308301 A1 ES8308301 A1 ES 8308301A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- ring
- hydrogen atom
- atom
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LOGJGBXRYQHJQT-UHFFFAOYSA-N tetracen-1-amine Chemical class C1=CC=C2C=C(C=C3C(N)=CC=CC3=C3)C3=CC2=C1 LOGJGBXRYQHJQT-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- -1 ethylenedioxy group Chemical group 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN PROCEDIMIENTO PAR LA PREPARACION DE DERIVADOS DE AMINONAFTACENO. SE HACE REACCIONAR EL COMPUESTO (II) CON UN COMPUESTO HALOGENANTE, PARA DAR EL COMPUESTO (III), EL CUAL A SU VEZ SE HACE REACCIONAR CON LA AMINA R>5-HN-R>6 PARA DAR EL 7-AMINO DE FORMULA GENERAL (I), DEL CUAL SE PUEDE ELIMINAR EL GRUPO ACETAL DE LA POSICION 13 PARA DAR EL 7-AMINO CORRESPONDIENTE; R ES UN ATOMO DE HIDROGENO, UN GRUPO HIDROXILO O UN GRUPO ALCOXI INFERIOR; R>2 ES UN ATOMO DE HIDROGENO O UN GRUPO HIDROXILO; R>5 Y R>6 SON CADA UNO DE ELLOS UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO INFERIOR U OTROS. ACTIVIDAD ANTITUMORAL.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11994981A JPS5821652A (ja) | 1981-07-29 | 1981-07-29 | アミノナフタセン誘導体とその製法 |
| JP1213482A JPS58128350A (ja) | 1982-01-27 | 1982-01-27 | 光学活性なアミノナフタセン誘導体とその製法 |
| JP7952582A JPS58198448A (ja) | 1982-05-11 | 1982-05-11 | アミノナフタセン誘導体とその製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8308301A1 true ES8308301A1 (es) | 1983-08-16 |
| ES514486A0 ES514486A0 (es) | 1983-08-16 |
Family
ID=27279716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES514486A Granted ES514486A0 (es) | 1981-07-29 | 1982-07-28 | Un procedimiento para la preparacion de derivados de aminonaftaceno. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4610986A (es) |
| EP (1) | EP0071483B1 (es) |
| CA (1) | CA1184902A (es) |
| DE (1) | DE3261765D1 (es) |
| ES (1) | ES514486A0 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58194845A (ja) * | 1982-05-07 | 1983-11-12 | Sumitomo Chem Co Ltd | アミノナフタセン誘導体とその製法 |
| US5077636A (en) * | 1989-11-30 | 1991-12-31 | Taiyo Yuden Co., Ltd. | Solid dielectric capacitor and method of manufacture |
| AT514868B1 (de) * | 2013-10-04 | 2015-11-15 | Genialistix Gmbh | Selbstschließender Ausgießer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI51808C (fi) * | 1968-07-15 | 1977-04-12 | Rhone Poulenc Sa | Menetelmä uusien kasvainten naftaseenijohdannaisten valmistamiseksi. |
| GB1461190A (en) * | 1974-09-20 | 1977-01-13 | Farmaceutici Italia | Anthracycline preparation |
| GB1500421A (en) * | 1975-01-22 | 1978-02-08 | Farmaceutici Italia | Optically active anthracyclinones |
| US4089872A (en) * | 1977-03-09 | 1978-05-16 | The Upjohn Company | Antibiotics steffimycinol and 7-deoxysteffimycinol and process for preparing the same |
| DE3100968A1 (de) * | 1980-01-16 | 1982-01-14 | Farmitalia Carlo Erba S.p.A., 20159 Milano | Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1982
- 1982-07-28 ES ES514486A patent/ES514486A0/es active Granted
- 1982-07-29 CA CA000408400A patent/CA1184902A/en not_active Expired
- 1982-07-29 EP EP82304021A patent/EP0071483B1/en not_active Expired
- 1982-07-29 DE DE8282304021T patent/DE3261765D1/de not_active Expired
-
1984
- 1984-10-12 US US06/660,039 patent/US4610986A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0071483B1 (en) | 1985-01-02 |
| DE3261765D1 (en) | 1985-02-14 |
| CA1184902A (en) | 1985-04-02 |
| EP0071483A2 (en) | 1983-02-09 |
| US4610986A (en) | 1986-09-09 |
| ES514486A0 (es) | 1983-08-16 |
| EP0071483A3 (en) | 1983-03-09 |
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