ATA30676A - Verfahren zur optischen trennung von racemischem 1,4-dimethoxy-6-hydroxy-6-acetyltetralin - Google Patents
Verfahren zur optischen trennung von racemischem 1,4-dimethoxy-6-hydroxy-6-acetyltetralinInfo
- Publication number
- ATA30676A ATA30676A AT30676A AT30676A ATA30676A AT A30676 A ATA30676 A AT A30676A AT 30676 A AT30676 A AT 30676A AT 30676 A AT30676 A AT 30676A AT A30676 A ATA30676 A AT A30676A
- Authority
- AT
- Austria
- Prior art keywords
- acetyltetralin
- dimethoxy
- racemic
- hydroxy
- optical separation
- Prior art date
Links
- AGUPHKGJZBMPMX-UHFFFAOYSA-N 1-(2-hydroxy-5,8-dimethoxy-5,6,7,8-tetrahydro-1h-naphthalen-2-yl)ethanone Chemical compound C1C(O)(C(C)=O)C=CC2=C1C(OC)CCC2OC AGUPHKGJZBMPMX-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT193477A AT346838B (de) | 1975-01-22 | 1976-01-19 | Verfahren zur herstellung von neuen optisch aktiven anthracyclinonen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2691/75A GB1500421A (en) | 1975-01-22 | 1975-01-22 | Optically active anthracyclinones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA30676A true ATA30676A (de) | 1977-07-15 |
| AT342035B AT342035B (de) | 1978-03-10 |
Family
ID=9744103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT30676A AT342035B (de) | 1975-01-22 | 1976-01-19 | Verfahren zur optischen trennung von racemischem 1,4-dimethoxy-6-hydroxy-6-acetyltetralin |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4077988A (de) |
| JP (4) | JPS6033819B2 (de) |
| AT (1) | AT342035B (de) |
| AU (1) | AU500067B2 (de) |
| BE (1) | BE837756A (de) |
| CA (1) | CA1064920A (de) |
| CH (3) | CH622486A5 (de) |
| DE (2) | DE2601785C2 (de) |
| DK (1) | DK155518C (de) |
| ES (1) | ES444494A1 (de) |
| FR (4) | FR2320105A1 (de) |
| GB (1) | GB1500421A (de) |
| HK (1) | HK1082A (de) |
| MX (1) | MX4278E (de) |
| NL (1) | NL179724C (de) |
| SE (4) | SE435498B (de) |
| SU (5) | SU683613A3 (de) |
| ZA (1) | ZA76292B (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4070382A (en) * | 1975-11-18 | 1978-01-24 | Research Corporation | Intermediates for polycyclic quinoid antibiotics |
| GB1527050A (en) * | 1976-06-19 | 1978-10-04 | Farmaceutici Italia | Optically active anthracyclinones |
| US4134903A (en) * | 1976-08-07 | 1979-01-16 | Societa Farmaceutici Italia S.P.A. | Anthracycline ethers and their preparation |
| GB1573037A (en) * | 1977-05-05 | 1980-08-13 | Farmaceutici Italia | Anthracyclines |
| GB1573036A (en) * | 1977-05-05 | 1980-08-13 | Farmaceutici Italia | Anthracyclines |
| US4296105A (en) * | 1978-08-03 | 1981-10-20 | Institut International De Pathologie Cellulaire Et Moleculaire | Derivatives of doxorubicine, their preparation and use |
| NL8001417A (nl) * | 1979-03-17 | 1980-09-19 | Erba Farmitalia | Antitumorglycosiden. |
| US4259476A (en) * | 1979-04-02 | 1981-03-31 | Kende Andrew S | Novel heterocyclic anthracycline compounds |
| GB2056443B (en) * | 1979-08-20 | 1984-01-18 | Hoffmann La Roche | Cyclic compounds |
| JPS5673039A (en) * | 1979-08-20 | 1981-06-17 | Hoffmann La Roche | Naphthacene derivative |
| GB2071084B (en) * | 1980-01-22 | 1984-02-29 | Hoffmann La Roche | Polycylic compounds |
| JPS5756494A (en) * | 1980-09-22 | 1982-04-05 | Microbial Chem Res Found | New anthracyclin derivative |
| ES514486A0 (es) * | 1981-07-29 | 1983-08-16 | Sumitomo Chemical Co | Un procedimiento para la preparacion de derivados de aminonaftaceno. |
| BE896743A (fr) * | 1982-08-13 | 1983-09-16 | Erba Farmitalia | Synthese de naphtacenequinone. |
| US4489206A (en) * | 1983-05-13 | 1984-12-18 | Adria Laboratories, Inc. | Synthesis of (+)-4-demethoxydaunomycinone |
| US4831019A (en) * | 1983-10-31 | 1989-05-16 | Adria Laboratories, Inc. | Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines |
| US4496485A (en) * | 1983-11-25 | 1985-01-29 | G. D. Searle & Co. | Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones |
| GB8519452D0 (en) * | 1985-08-02 | 1985-09-11 | Erba Farmitalia | Injectable solutions |
| MY103231A (en) * | 1987-03-11 | 1993-05-29 | Univ Melbourne | Immunoglobulin conjugates |
| NZ224252A (en) * | 1987-04-21 | 1991-09-25 | Erba Carlo Spa | An anthracycline glycoside and its preparation |
| GB8803301D0 (en) * | 1988-02-12 | 1988-03-09 | Erba Carlo Spa | Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin |
| GB8824947D0 (en) * | 1988-10-25 | 1988-11-30 | Erba Carlo Spa | New 4-substituted anthracyclinones & process for preparing them |
| NL9001834A (nl) * | 1990-08-16 | 1992-03-16 | Pharmachemie Bv | Nieuwe antracyclineverbindingen met anti-tumorwerkzaamheid, nieuwe tussenverbindingen voor de bereiding van deze antracyclineverbindingen, alsmede preparaten die de aktieve antracyclineverbindingen bevatten. |
| GB9418260D0 (en) * | 1994-09-09 | 1994-10-26 | Erba Carlo Spa | Anthracycline derivatives |
| IT1317106B1 (it) * | 2000-11-16 | 2003-05-26 | Menarini Ricerche Spa | Processo per la sintesi di antracicline otticamente attive. |
| DE10155016A1 (de) * | 2001-11-07 | 2003-05-15 | Knoell Hans Forschung Ev | Neue Chinon-Verbindung, Verfahren zur Herstellung und deren Verwendung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904632A (en) * | 1972-05-08 | 1975-09-09 | Hoffmann La Roche | (')-di-o-isopropylidene-2-keto-l-gulonates |
| JPS5840556A (ja) * | 1981-09-04 | 1983-03-09 | Ricoh Co Ltd | 電子写真圧力定着転写紙及びその転写紙用原紙の製造法 |
-
1975
- 1975-01-22 GB GB2691/75A patent/GB1500421A/en not_active Expired
-
1976
- 1976-01-06 NL NLAANVRAGE7600075,A patent/NL179724C/xx not_active IP Right Cessation
- 1976-01-16 US US05/649,825 patent/US4077988A/en not_active Expired - Lifetime
- 1976-01-19 ZA ZA292A patent/ZA76292B/xx unknown
- 1976-01-19 MX MX763633U patent/MX4278E/es unknown
- 1976-01-19 AT AT30676A patent/AT342035B/de not_active IP Right Cessation
- 1976-01-20 DE DE2601785A patent/DE2601785C2/de not_active Expired
- 1976-01-20 CA CA243,860A patent/CA1064920A/en not_active Expired
- 1976-01-20 AU AU10432/76A patent/AU500067B2/en not_active Expired
- 1976-01-20 DK DK020376A patent/DK155518C/da not_active IP Right Cessation
- 1976-01-20 JP JP51005803A patent/JPS6033819B2/ja not_active Expired
- 1976-01-20 DE DE2660848A patent/DE2660848C2/de not_active Expired
- 1976-01-20 SE SE7600563A patent/SE435498B/xx not_active IP Right Cessation
- 1976-01-21 FR FR7601535A patent/FR2320105A1/fr active Granted
- 1976-01-21 SU SU762311601A patent/SU683613A3/ru active
- 1976-01-21 CH CH74276A patent/CH622486A5/de not_active IP Right Cessation
- 1976-01-21 ES ES444494A patent/ES444494A1/es not_active Expired
- 1976-01-21 BE BE163665A patent/BE837756A/xx not_active IP Right Cessation
- 1976-09-24 FR FR7628763A patent/FR2320085A1/fr active Granted
- 1976-09-24 FR FR7628762A patent/FR2333769A1/fr active Granted
- 1976-09-24 FR FR7628764A patent/FR2320086A1/fr active Granted
- 1976-12-03 SU SU762425700A patent/SU646914A3/ru active
-
1977
- 1977-10-11 SU SU772530649A patent/SU724087A3/ru active
- 1977-10-11 SU SU772532447A patent/SU650498A3/ru active
- 1977-10-11 SU SU772532450A patent/SU776557A3/ru active
-
1980
- 1980-01-07 CH CH7780A patent/CH624085A5/de not_active IP Right Cessation
- 1980-01-07 CH CH7880A patent/CH622530A5/de not_active IP Right Cessation
-
1982
- 1982-01-14 HK HK10/82A patent/HK1082A/xx unknown
- 1982-02-18 SE SE8201013A patent/SE453185B/sv not_active IP Right Cessation
- 1982-02-18 SE SE8201014A patent/SE461525B/sv not_active IP Right Cessation
- 1982-02-18 SE SE8201015A patent/SE461529B/sv not_active IP Right Cessation
-
1984
- 1984-04-13 JP JP59073132A patent/JPS59231037A/ja active Pending
- 1984-04-13 JP JP59073134A patent/JPS59231098A/ja active Granted
- 1984-04-13 JP JP59073133A patent/JPS59231038A/ja active Pending
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties | ||
| EIH | Change in the person of patent owner | ||
| ELA | Expired due to lapse of time |