CA3178452A1 - Sustained-release dosage forms of ruxolitinib - Google Patents

Sustained-release dosage forms of ruxolitinib

Info

Publication number
CA3178452A1
CA3178452A1 CA3178452A CA3178452A CA3178452A1 CA 3178452 A1 CA3178452 A1 CA 3178452A1 CA 3178452 A CA3178452 A CA 3178452A CA 3178452 A CA3178452 A CA 3178452A CA 3178452 A1 CA3178452 A1 CA 3178452A1
Authority
CA
Canada
Prior art keywords
disease
cancer
sustained
ruxolitinib
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3178452A
Other languages
English (en)
French (fr)
Inventor
Yong Ni
Bhavnish Parikh
Krishnaswamy Yeleswaram
Susan Erickson-Viitanen
William V. Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Holdings Corp
Original Assignee
Incyte Holdings Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49681181&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3178452(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Holdings Corp filed Critical Incyte Holdings Corp
Publication of CA3178452A1 publication Critical patent/CA3178452A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
CA3178452A 2012-11-15 2013-11-14 Sustained-release dosage forms of ruxolitinib Pending CA3178452A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261726893P 2012-11-15 2012-11-15
US61/726,893 2012-11-15
US201361769408P 2013-02-26 2013-02-26
US61/769,408 2013-02-26
CA2890755A CA2890755C (en) 2012-11-15 2013-11-14 Sustained-release dosage forms of ruxolitinib

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2890755A Division CA2890755C (en) 2012-11-15 2013-11-14 Sustained-release dosage forms of ruxolitinib

Publications (1)

Publication Number Publication Date
CA3178452A1 true CA3178452A1 (en) 2014-05-22

Family

ID=49681181

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3178452A Pending CA3178452A1 (en) 2012-11-15 2013-11-14 Sustained-release dosage forms of ruxolitinib
CA2890755A Active CA2890755C (en) 2012-11-15 2013-11-14 Sustained-release dosage forms of ruxolitinib

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2890755A Active CA2890755C (en) 2012-11-15 2013-11-14 Sustained-release dosage forms of ruxolitinib

Country Status (34)

Country Link
US (9) US10166191B2 (https=)
EP (2) EP3949953A1 (https=)
JP (4) JP2015537030A (https=)
KR (3) KR20220162825A (https=)
CN (3) CN113384546A (https=)
AR (1) AR093490A1 (https=)
AU (4) AU2013344780B2 (https=)
BR (1) BR112015010663B1 (https=)
CA (2) CA3178452A1 (https=)
CL (1) CL2015001286A1 (https=)
CR (2) CR20190073A (https=)
CY (1) CY1124446T1 (https=)
DK (1) DK2919766T3 (https=)
EA (1) EA201590930A1 (https=)
ES (1) ES2880814T3 (https=)
HR (1) HRP20211158T1 (https=)
HU (1) HUE055894T2 (https=)
IL (4) IL291391B (https=)
LT (1) LT2919766T (https=)
MX (3) MX380147B (https=)
MY (1) MY191357A (https=)
NZ (2) NZ708157A (https=)
PE (2) PE20200175A1 (https=)
PH (2) PH12020551186B1 (https=)
PL (1) PL2919766T3 (https=)
PT (1) PT2919766T (https=)
RS (1) RS62329B1 (https=)
SG (3) SG10201703685UA (https=)
SI (1) SI2919766T1 (https=)
SM (1) SMT202100436T1 (https=)
TW (4) TW201922255A (https=)
UA (1) UA120834C2 (https=)
WO (1) WO2014078486A1 (https=)
ZA (1) ZA202202711B (https=)

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EP3070090B1 (en) 2007-06-13 2018-12-12 Incyte Holdings Corporation Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
SG176111A1 (en) 2009-05-22 2011-12-29 Incyte Corp 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
JP5775070B2 (ja) 2009-05-22 2015-09-09 インサイト・コーポレイションＩｎｃｙｔｅ Ｃｏｒｐｏｒａｔｉｏｎ ヤヌスキナーゼ阻害剤としてのピラゾール−４−イル−ピロロ［２，３−ｄ］ピリミジンおよびピロール−３−イル−ピロロ［２，３−ｄ］ピリミジンのＮ−（ヘテロ）アリール−ピロリジン誘導体
PT3354652T (pt) 2010-03-10 2020-07-20 Incyte Holdings Corp Derivados de piperidin-4-ilazetidina como inibidores de jak1
RS54824B1 (sr) 2010-05-21 2016-10-31 Incyte Holdings Corp Topikalna formulacija za inhibiciju jak-a
CA2818542A1 (en) 2010-11-19 2012-05-24 Incyte Corporation Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
MY165963A (en) 2011-06-20 2018-05-18 Incyte Holdings Corp Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
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CN113384546A (zh) 2012-11-15 2021-09-14 因赛特公司 鲁索利替尼的缓释剂型
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PH12020552277A1 (en) 2014-04-08 2023-07-17 Incyte Holdings Corp Treatment of b-cell malignancies by a combination jak and pi3k inhibitor
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