CA2812704C - Formulations for bovine granulocyte colony stimulating factor and variants thereof - Google Patents

Formulations for bovine granulocyte colony stimulating factor and variants thereof Download PDF

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Publication number
CA2812704C
CA2812704C CA2812704A CA2812704A CA2812704C CA 2812704 C CA2812704 C CA 2812704C CA 2812704 A CA2812704 A CA 2812704A CA 2812704 A CA2812704 A CA 2812704A CA 2812704 C CA2812704 C CA 2812704C
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CA
Canada
Prior art keywords
formulation
arginine
csf
animal
buffer
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CA2812704A
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English (en)
French (fr)
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CA2812704A1 (en
Inventor
Juan Davagnino
Catherine Ngan Kha
Alan Voskamp Klotz
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Elanco US Inc
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Eli Lilly and Co
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Publication of CA2812704A1 publication Critical patent/CA2812704A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2812704A 2010-09-23 2011-09-22 Formulations for bovine granulocyte colony stimulating factor and variants thereof Active CA2812704C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38562910P 2010-09-23 2010-09-23
US61/385,629 2010-09-23
PCT/US2011/052692 WO2012040421A1 (en) 2010-09-23 2011-09-22 Formulations for bovine granulocyte colony stimulating factor and variants thereof

Publications (2)

Publication Number Publication Date
CA2812704A1 CA2812704A1 (en) 2012-03-29
CA2812704C true CA2812704C (en) 2016-03-15

Family

ID=44721111

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2812704A Active CA2812704C (en) 2010-09-23 2011-09-22 Formulations for bovine granulocyte colony stimulating factor and variants thereof

Country Status (33)

Country Link
US (3) US11273202B2 (https=)
EP (1) EP2618830B1 (https=)
JP (1) JP5798628B2 (https=)
KR (2) KR20130055665A (https=)
CN (1) CN103096916B (https=)
AR (1) AR083006A1 (https=)
AU (1) AU2011305386B2 (https=)
BR (1) BR112013005697B1 (https=)
CA (1) CA2812704C (https=)
CL (1) CL2013000771A1 (https=)
CO (1) CO6690780A2 (https=)
CR (1) CR20130067A (https=)
DK (1) DK2618830T3 (https=)
EA (1) EA026073B1 (https=)
ES (1) ES2540862T3 (https=)
HR (1) HRP20150476T1 (https=)
IL (1) IL224848A (https=)
MA (1) MA34585B1 (https=)
ME (1) ME02103B (https=)
MX (1) MX342624B (https=)
MY (1) MY161665A (https=)
NZ (1) NZ608164A (https=)
PE (1) PE20131339A1 (https=)
PH (1) PH12013500538A1 (https=)
PL (1) PL2618830T3 (https=)
PT (1) PT2618830E (https=)
RS (1) RS53962B1 (https=)
SG (1) SG188287A1 (https=)
SI (1) SI2618830T1 (https=)
TW (1) TWI480288B (https=)
UA (1) UA110799C2 (https=)
WO (1) WO2012040421A1 (https=)
ZA (1) ZA201301208B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI480288B (zh) * 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
AU2018348138A1 (en) * 2017-10-11 2020-04-23 Ambrx, Inc. Porcine G-CSF variants and their uses

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CO6690780A2 (es) 2013-06-17
KR101563852B1 (ko) 2015-10-27
CA2812704A1 (en) 2012-03-29
JP5798628B2 (ja) 2015-10-21
MX342624B (es) 2016-10-05
US11273202B2 (en) 2022-03-15
BR112013005697A2 (pt) 2018-05-08
EP2618830A1 (en) 2013-07-31
AU2011305386B2 (en) 2014-06-12
UA110799C2 (uk) 2016-02-25
AU2011305386A1 (en) 2013-03-14
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CN103096916A (zh) 2013-05-08
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US20250134960A1 (en) 2025-05-01
US20120082641A1 (en) 2012-04-05
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