BRPI0510093B8 - polímeros dendríticos - Google Patents

polímeros dendríticos

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Publication number
BRPI0510093B8
BRPI0510093B8 BRPI0510093A BRPI0510093A BRPI0510093B8 BR PI0510093 B8 BRPI0510093 B8 BR PI0510093B8 BR PI0510093 A BRPI0510093 A BR PI0510093A BR PI0510093 A BRPI0510093 A BR PI0510093A BR PI0510093 B8 BRPI0510093 B8 BR PI0510093B8
Authority
BR
Brazil
Prior art keywords
dendritic polymers
functionality
dendritic
polyfunctional
generation
Prior art date
Application number
BRPI0510093A
Other languages
English (en)
Inventor
A Tomalia Donald
R Swanson Douglas
Huang Baohua
Reddy Pulgam Veera
Original Assignee
Dendritic Nanotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dendritic Nanotechnologies Inc filed Critical Dendritic Nanotechnologies Inc
Publication of BRPI0510093A publication Critical patent/BRPI0510093A/pt
Publication of BRPI0510093A8 publication Critical patent/BRPI0510093A8/pt
Publication of BRPI0510093B1 publication Critical patent/BRPI0510093B1/pt
Publication of BRPI0510093B8 publication Critical patent/BRPI0510093B8/pt

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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F279/00Macromolecular compounds obtained by polymerising monomers on to polymers of monomers having two or more carbon-to-carbon double bonds as defined in group C08F36/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F279/00Macromolecular compounds obtained by polymerising monomers on to polymers of monomers having two or more carbon-to-carbon double bonds as defined in group C08F36/00
    • C08F279/02Macromolecular compounds obtained by polymerising monomers on to polymers of monomers having two or more carbon-to-carbon double bonds as defined in group C08F36/00 on to polymers of conjugated dienes
    • C08F279/04Vinyl aromatic monomers and nitriles as the only monomers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/14Polycondensates modified by chemical after-treatment
    • C08G59/1433Polycondensates modified by chemical after-treatment with organic low-molecular-weight compounds
    • C08G59/1477Polycondensates modified by chemical after-treatment with organic low-molecular-weight compounds containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/20Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the epoxy compounds used
    • C08G59/32Epoxy compounds containing three or more epoxy groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/20Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the epoxy compounds used
    • C08G59/32Epoxy compounds containing three or more epoxy groups
    • C08G59/3227Compounds containing acyclic nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G59/00Polycondensates containing more than one epoxy group per molecule; Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups
    • C08G59/18Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing
    • C08G59/40Macromolecules obtained by polymerising compounds containing more than one epoxy group per molecule using curing agents or catalysts which react with the epoxy groups ; e.g. general methods of curing characterised by the curing agents used
    • C08G59/50Amines
    • C08G59/5026Amines cycloaliphatic
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Epoxy Resins (AREA)
  • Medicinal Preparation (AREA)
  • Polyethers (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyamides (AREA)

Abstract

polímeros dendríticos com amplificação intensificada e funcionalidade interior. a presente invenção refere-se a polímeros dendríticos com amplificação intensificada e funcionalidade interior são descritos. estes polímeros dendríticos são feitos pelo uso de química de abertura de anel, reativa, rápida (ou outras reações rápidas) combinadas com o uso de reagentes de célula de ramificação em um modo controlado para rápida e precisamente construir estruturas de dendrímero, geração por geração, com estruturas precisas com química mais limpa, tipicamente produtos simples, excessos inferiores de reagentes, níveis inferiores de diluição, método de capacidade mais alta, escala mais fácil para dimensões comerciais, faixas novas de materiais e custo inferior. a composição de dendrímero preparada tem funcionalidade interna nova, maior estabilidade, exemplo, estabilidade térmica, e menos ou nenhuma reação de michael reversa, e que alcança densidades de superfície de encapsulação em gerações inferiores. inesperadamente, estas reações de reagentes de célula de ramificação polifuncionais com superfícies polifuncionais não criam materiais de gel. tais polímeros dendríticos são úteis como desemulsificantes para emulsões de óleo/água, agentes de resistência a úmido na fabricação de papel, descontaminantes de prótons, padrões de calibração para microscopia de elétron, fazer membranas seletivas em tamanho e agentes para modificar a viscosidade em formulações aquosas como pintura. quando estes polímeros dendríticos têm um material carregado associado com sua superfície e/ou interior, então estes dendríticos têm propriedades adicionais devido às únicas características do polímero dendrítico.
BRPI0510093A 2004-04-20 2005-04-20 polímeros dendríticos BRPI0510093B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56365904P 2004-04-20 2004-04-20
US60/563,659 2004-04-20
PCT/US2005/013864 WO2006065266A2 (en) 2004-04-20 2005-04-20 Dendritic polymers with enhanced amplification and interior functionality

Publications (4)

Publication Number Publication Date
BRPI0510093A BRPI0510093A (pt) 2007-10-16
BRPI0510093A8 BRPI0510093A8 (pt) 2017-12-12
BRPI0510093B1 BRPI0510093B1 (pt) 2018-04-10
BRPI0510093B8 true BRPI0510093B8 (pt) 2022-12-27

Family

ID=36588292

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0510093A BRPI0510093B8 (pt) 2004-04-20 2005-04-20 polímeros dendríticos
BRPI0512282A BRPI0512282A8 (pt) 2004-04-20 2005-12-21 Polímeros dendríticos com amplificação intensificada e funcionalidade interior

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0512282A BRPI0512282A8 (pt) 2004-04-20 2005-12-21 Polímeros dendríticos com amplificação intensificada e funcionalidade interior

Country Status (16)

Country Link
US (1) US7981444B2 (pt)
EP (2) EP1737899B1 (pt)
JP (2) JP4510881B2 (pt)
KR (1) KR100843362B1 (pt)
CN (2) CN1946772B (pt)
AU (1) AU2005317193A1 (pt)
BR (2) BRPI0510093B8 (pt)
CA (1) CA2564780C (pt)
DK (1) DK1737899T3 (pt)
ES (1) ES2547220T3 (pt)
HK (1) HK1104832A1 (pt)
IL (1) IL178715A (pt)
MX (1) MXPA06012207A (pt)
NZ (1) NZ550604A (pt)
PL (1) PL1737899T3 (pt)
WO (1) WO2006065266A2 (pt)

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