IT1277596B1 - Composti macromolecolari di tipo dendrimerico - Google Patents

Composti macromolecolari di tipo dendrimerico

Info

Publication number
IT1277596B1
IT1277596B1 IT95MI001929A ITMI951929A IT1277596B1 IT 1277596 B1 IT1277596 B1 IT 1277596B1 IT 95MI001929 A IT95MI001929 A IT 95MI001929A IT MI951929 A ITMI951929 A IT MI951929A IT 1277596 B1 IT1277596 B1 IT 1277596B1
Authority
IT
Italy
Prior art keywords
macromolecular compounds
dendrimeric
type
dendrimeric type
dendra
Prior art date
Application number
IT95MI001929A
Other languages
English (en)
Inventor
Luigia Gozzini
Monica Muttoni
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Publication of ITMI951929A0 publication Critical patent/ITMI951929A0/it
Priority to IT95MI001929A priority Critical patent/IT1277596B1/it
Priority to DE69612987T priority patent/DE69612987T2/de
Priority to KR1019980701845A priority patent/KR19990044595A/ko
Priority to PCT/EP1996/003934 priority patent/WO1997010281A1/en
Priority to EP96931048A priority patent/EP0850262B1/en
Priority to AT96931048T priority patent/ATE201425T1/de
Priority to CA002231840A priority patent/CA2231840A1/en
Priority to AU69881/96A priority patent/AU717922B2/en
Priority to JP9511637A priority patent/JPH11514396A/ja
Priority to US08/713,832 priority patent/US5807971A/en
Priority to ZA9607759A priority patent/ZA967759B/xx
Publication of ITMI951929A1 publication Critical patent/ITMI951929A1/it
Application granted granted Critical
Publication of IT1277596B1 publication Critical patent/IT1277596B1/it
Priority to NO19981092A priority patent/NO315658B1/no
Priority to US09/075,167 priority patent/US5994495A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002Dendritic macromolecules
    • C08G83/003Dendrimers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/16Dendrimers and dendritic polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Polyamides (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
IT95MI001929A 1995-09-15 1995-09-15 Composti macromolecolari di tipo dendrimerico IT1277596B1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT95MI001929A IT1277596B1 (it) 1995-09-15 1995-09-15 Composti macromolecolari di tipo dendrimerico
CA002231840A CA2231840A1 (en) 1995-09-15 1996-09-09 Selectively functionalizable desdendrimers
JP9511637A JPH11514396A (ja) 1995-09-15 1996-09-09 選択的に官能化しうるデスデンドリマー類
PCT/EP1996/003934 WO1997010281A1 (en) 1995-09-15 1996-09-09 Selectively functionalizable desdendrimers
EP96931048A EP0850262B1 (en) 1995-09-15 1996-09-09 Selectively functionalizable desdendrimers
AT96931048T ATE201425T1 (de) 1995-09-15 1996-09-09 Selektiv funktionalisierbare desdendrimere
DE69612987T DE69612987T2 (de) 1995-09-15 1996-09-09 Selektiv funktionalisierbare desdendrimere
AU69881/96A AU717922B2 (en) 1995-09-15 1996-09-09 Selectively functionalizable desdendrimers
KR1019980701845A KR19990044595A (ko) 1995-09-15 1996-09-09 선택적으로 관능화 가능한 데스덴드리머
US08/713,832 US5807971A (en) 1995-09-15 1996-09-13 Selectively functionalizable desdendrimers
ZA9607759A ZA967759B (en) 1995-09-15 1996-09-13 Selectively functionalizable desdendrimers.
NO19981092A NO315658B1 (no) 1995-09-15 1998-03-12 Selektivt funksjonelle desdendrimere makromolekyler, fremgangsmåte for fremstilling av de samme og deres anvendelse
US09/075,167 US5994495A (en) 1995-09-15 1998-05-11 Selectively functionalizable desdendrimers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95MI001929A IT1277596B1 (it) 1995-09-15 1995-09-15 Composti macromolecolari di tipo dendrimerico

Publications (3)

Publication Number Publication Date
ITMI951929A0 ITMI951929A0 (it) 1995-09-15
ITMI951929A1 ITMI951929A1 (it) 1997-03-15
IT1277596B1 true IT1277596B1 (it) 1997-11-11

Family

ID=11372253

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95MI001929A IT1277596B1 (it) 1995-09-15 1995-09-15 Composti macromolecolari di tipo dendrimerico

Country Status (12)

Country Link
US (2) US5807971A (it)
EP (1) EP0850262B1 (it)
JP (1) JPH11514396A (it)
KR (1) KR19990044595A (it)
AT (1) ATE201425T1 (it)
AU (1) AU717922B2 (it)
CA (1) CA2231840A1 (it)
DE (1) DE69612987T2 (it)
IT (1) IT1277596B1 (it)
NO (1) NO315658B1 (it)
WO (1) WO1997010281A1 (it)
ZA (1) ZA967759B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277596B1 (it) * 1995-09-15 1997-11-11 Bracco Spa Composti macromolecolari di tipo dendrimerico
US6310043B1 (en) 1998-08-07 2001-10-30 Governors Of The University Of Alberta Treatment of bacterial infections
US5962423A (en) * 1998-08-07 1999-10-05 The Governors Of The University Of Alberta Treatment of bacterial dysentery
EP1179026A4 (en) 1998-11-05 2003-04-02 Univ Illinois BRANCHED AND HYPERRAMIFIED POLYETHERIMIDES FROM STABLE MONOMERS A1BN, AB, AA AND BB AND AM TERMINAL HAIRDRESSING AGENTS
US6258896B1 (en) 1998-12-18 2001-07-10 3M Innovative Properties Company Dendritic polymer dispersants for hydrophobic particles in water-based systems
US6262207B1 (en) 1998-12-18 2001-07-17 3M Innovative Properties Company ABN dispersants for hydrophobic particles in water-based systems
US6395804B1 (en) 1998-12-18 2002-05-28 3M Innovative Properties Company Polyelectrolyte dispersants for hydrophobic particles in water-based systems
AU6386000A (en) 1999-07-29 2001-02-19 Epix Pharmaceuticals, Inc. Targeting multimeric imaging agents through multilocus binding
WO2001048052A1 (fr) 1999-12-24 2001-07-05 Kyowa Hakko Kogyo Co., Ltd. Glycols de polyalkylene ramifies
JP4680351B2 (ja) * 2000-07-05 2011-05-11 日本曹達株式会社 スターポリマー
TWI241287B (en) * 2000-11-24 2005-10-11 Nat Institue Of Information An Novel thioether derivatives
ATE471956T1 (de) 2001-01-30 2010-07-15 Kyowa Hakko Kirin Co Ltd Verzweigte polyalkylenglykole
TWI221406B (en) 2001-07-30 2004-10-01 Epix Medical Inc Systems and methods for targeted magnetic resonance imaging of the vascular system
DE10318584A1 (de) * 2003-04-24 2004-11-11 Basf Ag Hochverzweigte polymere Stabilisatoren
KR100612079B1 (ko) * 2003-10-09 2006-08-11 주식회사 엘지화학 방사형 다분지 고분자 및 이를 이용한 다공성 막
US7985424B2 (en) 2004-04-20 2011-07-26 Dendritic Nanotechnologies Inc. Dendritic polymers with enhanced amplification and interior functionality
US7981444B2 (en) * 2004-04-20 2011-07-19 Dendritic Nanotechnologies, Inc. Dendritic polymers with enhanced amplification and interior functionality
CA2598430C (en) * 2005-04-20 2011-10-25 Dendritic Nanotechnologies, Inc. Dendritic polymers with enhanced amplification and interior functionality
KR20100065190A (ko) * 2007-09-14 2010-06-15 닛토덴코 가부시키가이샤 약물 담체
EP2133064A1 (en) * 2008-06-10 2009-12-16 3M Innovative Properties Company Initiator system containing a diarylalkylamine derivate, hardenable composition and use thereof
US8841382B2 (en) * 2010-09-01 2014-09-23 Basf Se Hyperbranched polyethers/dendrimers for solubilzation of sparingly soluble active ingredients

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4568737A (en) * 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US4737550A (en) * 1983-01-07 1988-04-12 The Dow Chemical Company Bridged dense star polymers
US4587329A (en) * 1984-08-17 1986-05-06 The Dow Chemical Company Dense star polymers having two dimensional molecular diameter
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer
US4857599A (en) * 1988-02-08 1989-08-15 The Dow Chemical Company Modified dense star polymers
US5041516A (en) * 1989-06-21 1991-08-20 Cornell Research Foundation, Inc. Dendritic molecules and method of production
US5530092A (en) * 1992-01-13 1996-06-25 Dsm N.V. Dendritic macromolecule and the preparation thereof
IT1270994B (it) * 1994-03-18 1997-05-26 Bracco Spa Macromolecole ramificate a struttura poliossialchilica e loro usi
IT1277596B1 (it) * 1995-09-15 1997-11-11 Bracco Spa Composti macromolecolari di tipo dendrimerico

Also Published As

Publication number Publication date
AU717922B2 (en) 2000-04-06
ZA967759B (en) 1998-03-13
US5807971A (en) 1998-09-15
WO1997010281A1 (en) 1997-03-20
DE69612987T2 (de) 2001-10-18
ITMI951929A0 (it) 1995-09-15
NO981092L (no) 1998-03-12
ATE201425T1 (de) 2001-06-15
NO315658B1 (no) 2003-10-06
DE69612987D1 (de) 2001-06-28
US5994495A (en) 1999-11-30
CA2231840A1 (en) 1997-03-20
NO981092D0 (no) 1998-03-12
ITMI951929A1 (it) 1997-03-15
EP0850262A1 (en) 1998-07-01
JPH11514396A (ja) 1999-12-07
KR19990044595A (ko) 1999-06-25
EP0850262B1 (en) 2001-05-23
AU6988196A (en) 1997-04-01

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