ATE201425T1 - Selektiv funktionalisierbare desdendrimere - Google Patents

Selektiv funktionalisierbare desdendrimere

Info

Publication number
ATE201425T1
ATE201425T1 AT96931048T AT96931048T ATE201425T1 AT E201425 T1 ATE201425 T1 AT E201425T1 AT 96931048 T AT96931048 T AT 96931048T AT 96931048 T AT96931048 T AT 96931048T AT E201425 T1 ATE201425 T1 AT E201425T1
Authority
AT
Austria
Prior art keywords
desdendrimers
functionalizable
selectively
dendra
polyoxaalkylene
Prior art date
Application number
AT96931048T
Other languages
English (en)
Inventor
Luigia Gozzini
Monica Muttoni
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Application granted granted Critical
Publication of ATE201425T1 publication Critical patent/ATE201425T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/16—Dendrimers and dendritic polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Polyamides (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Graft Or Block Polymers (AREA)
AT96931048T 1995-09-15 1996-09-09 Selektiv funktionalisierbare desdendrimere ATE201425T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001929A IT1277596B1 (it) 1995-09-15 1995-09-15 Composti macromolecolari di tipo dendrimerico
PCT/EP1996/003934 WO1997010281A1 (en) 1995-09-15 1996-09-09 Selectively functionalizable desdendrimers

Publications (1)

Publication Number Publication Date
ATE201425T1 true ATE201425T1 (de) 2001-06-15

Family

ID=11372253

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96931048T ATE201425T1 (de) 1995-09-15 1996-09-09 Selektiv funktionalisierbare desdendrimere

Country Status (12)

Country Link
US (2) US5807971A (de)
EP (1) EP0850262B1 (de)
JP (1) JPH11514396A (de)
KR (1) KR19990044595A (de)
AT (1) ATE201425T1 (de)
AU (1) AU717922B2 (de)
CA (1) CA2231840A1 (de)
DE (1) DE69612987T2 (de)
IT (1) IT1277596B1 (de)
NO (1) NO315658B1 (de)
WO (1) WO1997010281A1 (de)
ZA (1) ZA967759B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277596B1 (it) * 1995-09-15 1997-11-11 Bracco Spa Composti macromolecolari di tipo dendrimerico
US5962423A (en) * 1998-08-07 1999-10-05 The Governors Of The University Of Alberta Treatment of bacterial dysentery
US6310043B1 (en) 1998-08-07 2001-10-30 Governors Of The University Of Alberta Treatment of bacterial infections
US6333390B1 (en) 1998-11-05 2001-12-25 The Board Of Trustees Of The University Of Illinois Branched and hyperbranched polyetherimides
US6262207B1 (en) 1998-12-18 2001-07-17 3M Innovative Properties Company ABN dispersants for hydrophobic particles in water-based systems
US6258896B1 (en) 1998-12-18 2001-07-10 3M Innovative Properties Company Dendritic polymer dispersants for hydrophobic particles in water-based systems
US6395804B1 (en) 1998-12-18 2002-05-28 3M Innovative Properties Company Polyelectrolyte dispersants for hydrophobic particles in water-based systems
HUP0202635A3 (en) 1999-07-29 2006-03-28 Epix Medical Inc Cambridge Targeting multimeric imaging agents through multilocus binding
JP4593048B2 (ja) * 1999-12-24 2010-12-08 協和発酵キリン株式会社 分岐型ポリアルキレングリコール類
JP4680351B2 (ja) * 2000-07-05 2011-05-11 日本曹達株式会社 スターポリマー
TW588036B (en) * 2000-11-24 2004-05-21 Comm Res Lab Independent Ad Novel thioether derivatives, their production and use
DE60236796D1 (de) 2001-01-30 2010-08-05 Kyowa Hakko Kirin Co Ltd Verzweigte polyalkylenglykole
TWI221406B (en) 2001-07-30 2004-10-01 Epix Medical Inc Systems and methods for targeted magnetic resonance imaging of the vascular system
DE10318584A1 (de) * 2003-04-24 2004-11-11 Basf Ag Hochverzweigte polymere Stabilisatoren
KR100612079B1 (ko) * 2003-10-09 2006-08-11 주식회사 엘지화학 방사형 다분지 고분자 및 이를 이용한 다공성 막
BRPI0510093B8 (pt) * 2004-04-20 2022-12-27 Dendritic Nanotechnologies Inc polímeros dendríticos
US7985424B2 (en) 2004-04-20 2011-07-26 Dendritic Nanotechnologies Inc. Dendritic polymers with enhanced amplification and interior functionality
CA2598430C (en) * 2005-04-20 2011-10-25 Dendritic Nanotechnologies, Inc. Dendritic polymers with enhanced amplification and interior functionality
JP2010539245A (ja) * 2007-09-14 2010-12-16 日東電工株式会社 薬物担体
EP2133064A1 (de) * 2008-06-10 2009-12-16 3M Innovative Properties Company Initiatorsystem mit einem Diarylalkylamin-Derivat, härtbare Zusammensetzung und deren Verwendung
US8841382B2 (en) * 2010-09-01 2014-09-23 Basf Se Hyperbranched polyethers/dendrimers for solubilzation of sparingly soluble active ingredients

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737550A (en) * 1983-01-07 1988-04-12 The Dow Chemical Company Bridged dense star polymers
US4568737A (en) * 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4587329A (en) * 1984-08-17 1986-05-06 The Dow Chemical Company Dense star polymers having two dimensional molecular diameter
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer
US4857599A (en) * 1988-02-08 1989-08-15 The Dow Chemical Company Modified dense star polymers
US5041516A (en) * 1989-06-21 1991-08-20 Cornell Research Foundation, Inc. Dendritic molecules and method of production
US5530092A (en) * 1992-01-13 1996-06-25 Dsm N.V. Dendritic macromolecule and the preparation thereof
IT1270994B (it) * 1994-03-18 1997-05-26 Bracco Spa Macromolecole ramificate a struttura poliossialchilica e loro usi
IT1277596B1 (it) * 1995-09-15 1997-11-11 Bracco Spa Composti macromolecolari di tipo dendrimerico

Also Published As

Publication number Publication date
DE69612987D1 (de) 2001-06-28
EP0850262A1 (de) 1998-07-01
ZA967759B (en) 1998-03-13
NO981092D0 (no) 1998-03-12
ITMI951929A1 (it) 1997-03-15
NO315658B1 (no) 2003-10-06
US5807971A (en) 1998-09-15
AU6988196A (en) 1997-04-01
IT1277596B1 (it) 1997-11-11
JPH11514396A (ja) 1999-12-07
KR19990044595A (ko) 1999-06-25
NO981092L (no) 1998-03-12
EP0850262B1 (de) 2001-05-23
US5994495A (en) 1999-11-30
ITMI951929A0 (it) 1995-09-15
AU717922B2 (en) 2000-04-06
WO1997010281A1 (en) 1997-03-20
CA2231840A1 (en) 1997-03-20
DE69612987T2 (de) 2001-10-18

Similar Documents

Publication Publication Date Title
DE69612987D1 (de) Selektiv funktionalisierbare desdendrimere
DE68907397D1 (de) Fluessige photopolymerisierbare zusammensetzung, viskoelastisches produkt, erhalten aus dieser zusammensetzung und verfahren zur herstellung dieses viskoelastischen produktes.
ATE83927T1 (de) Thrombinzusammensetzung.
NO900855D0 (no) Substituerte pyrroler.
ATE242216T1 (de) Tricyclische verbindungen als inhibitoren von farnesyl protein transferase
ATE266671T1 (de) Nukleinsäuresynthese unter verwendung von mittels licht abspaltbaren schutzgruppen
EA199700170A1 (ru) Способ получения некоторых азациклогексапетидов
ATE202940T1 (de) Mittel und methoden zur behandlung von plaque- krankheiten
DE69725171D1 (de) Substituierte pyrrolylverbindungen zur behandlung von entzündungen
ATE239079T1 (de) Gewebeinhibitor für metalloproteasen type 3 (timp-3)
TR199801179T2 (xx) Yeni taksoitler, bunlar�n haz�rlanmalar� ve ila� bile�imleri.
ES2138154T3 (es) Copolicarbonato.
FI973571A (fi) Uusi kasvutekijä ja sitä koodaava geneettinen sekvenssi
DE69405919D1 (de) Zusammensetzungen zur Behandlung von Keratinfasern
BE882420A (fr) Nouveaux derives d'alpha-(3,4-dichlorophenyl)-imidazoline ou pyrimidine-2-methanols utiles notamment comme agents antisecretoires et leur procede de preparation
ATE248156T1 (de) Verwendung von 7-acyltaxolen zur behandlung von multidrugresistenten zellen
DE69509223D1 (de) Substituierte spiroverbindungen zur behandlung von entzündungen
ATE271394T1 (de) Hybride zusammensetzungen für intrazellulaire verabreichung
DE69606656D1 (de) Herstellung von meneralkahlfasern durch schleudern
ATE276274T1 (de) Konjugate von alpha-msh mit einer fettsäure, verfahren zu ihrer herstellung und ihre verwendung als medikament
ATE265533T1 (de) Saeugetierchemokine
DE69734596D1 (de) "smoothened" proteine aus wirbeltieren
BR9609114A (pt) Composição inseticida de terra diatomácea
BR9813281A (pt) Compostos de 4,5-diariloxazol, processos para sua preparação, composição farmacêutica contendo o mesmo, e seu uso
DE69630761D1 (de) Verfahren zur verminderung der renalen aufnahme von antikörperfragmenten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties