DE69612987T2 - Selektiv funktionalisierbare desdendrimere - Google Patents

Selektiv funktionalisierbare desdendrimere

Info

Publication number
DE69612987T2
DE69612987T2 DE69612987T DE69612987T DE69612987T2 DE 69612987 T2 DE69612987 T2 DE 69612987T2 DE 69612987 T DE69612987 T DE 69612987T DE 69612987 T DE69612987 T DE 69612987T DE 69612987 T2 DE69612987 T2 DE 69612987T2
Authority
DE
Germany
Prior art keywords
desdendrimers
functionalizable
selectively
dendra
polyoxaalkylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69612987T
Other languages
English (en)
Other versions
DE69612987D1 (de
Inventor
Luigia Gozzini
Monica Muttoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Imaging SpA
Original Assignee
Bracco Imaging SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging SpA filed Critical Bracco Imaging SpA
Application granted granted Critical
Publication of DE69612987D1 publication Critical patent/DE69612987D1/de
Publication of DE69612987T2 publication Critical patent/DE69612987T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/16—Dendrimers and dendritic polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Graft Or Block Polymers (AREA)
  • Polyamides (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE69612987T 1995-09-15 1996-09-09 Selektiv funktionalisierbare desdendrimere Expired - Fee Related DE69612987T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001929A IT1277596B1 (it) 1995-09-15 1995-09-15 Composti macromolecolari di tipo dendrimerico
PCT/EP1996/003934 WO1997010281A1 (en) 1995-09-15 1996-09-09 Selectively functionalizable desdendrimers

Publications (2)

Publication Number Publication Date
DE69612987D1 DE69612987D1 (de) 2001-06-28
DE69612987T2 true DE69612987T2 (de) 2001-10-18

Family

ID=11372253

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69612987T Expired - Fee Related DE69612987T2 (de) 1995-09-15 1996-09-09 Selektiv funktionalisierbare desdendrimere

Country Status (12)

Country Link
US (2) US5807971A (de)
EP (1) EP0850262B1 (de)
JP (1) JPH11514396A (de)
KR (1) KR19990044595A (de)
AT (1) ATE201425T1 (de)
AU (1) AU717922B2 (de)
CA (1) CA2231840A1 (de)
DE (1) DE69612987T2 (de)
IT (1) IT1277596B1 (de)
NO (1) NO315658B1 (de)
WO (1) WO1997010281A1 (de)
ZA (1) ZA967759B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277596B1 (it) * 1995-09-15 1997-11-11 Bracco Spa Composti macromolecolari di tipo dendrimerico
US6310043B1 (en) 1998-08-07 2001-10-30 Governors Of The University Of Alberta Treatment of bacterial infections
US5962423A (en) * 1998-08-07 1999-10-05 The Governors Of The University Of Alberta Treatment of bacterial dysentery
US6333390B1 (en) 1998-11-05 2001-12-25 The Board Of Trustees Of The University Of Illinois Branched and hyperbranched polyetherimides
US6262207B1 (en) 1998-12-18 2001-07-17 3M Innovative Properties Company ABN dispersants for hydrophobic particles in water-based systems
US6258896B1 (en) 1998-12-18 2001-07-10 3M Innovative Properties Company Dendritic polymer dispersants for hydrophobic particles in water-based systems
US6395804B1 (en) 1998-12-18 2002-05-28 3M Innovative Properties Company Polyelectrolyte dispersants for hydrophobic particles in water-based systems
JP2003505519A (ja) 1999-07-29 2003-02-12 エピックス メディカル， インコーポレイテッド 多座結合を介した多量体画像化剤の標的化
US7691367B2 (en) * 1999-12-24 2010-04-06 Kyowa Hakko Kirin Co., Ltd. Branched polyalkylene glycols
JP4680351B2 (ja) * 2000-07-05 2011-05-11 日本曹達株式会社 スターポリマー
TW588036B (en) * 2000-11-24 2004-05-21 Comm Res Lab Independent Ad Novel thioether derivatives, their production and use
WO2002060978A1 (fr) 2001-01-30 2002-08-08 Kyowa Hakko Kogyo Co., Ltd. Polyalkylene glycols ramifies
TWI221406B (en) 2001-07-30 2004-10-01 Epix Medical Inc Systems and methods for targeted magnetic resonance imaging of the vascular system
DE10318584A1 (de) * 2003-04-24 2004-11-11 Basf Ag Hochverzweigte polymere Stabilisatoren
KR100612079B1 (ko) * 2003-10-09 2006-08-11 주식회사 엘지화학 방사형 다분지 고분자 및 이를 이용한 다공성 막
KR100843362B1 (ko) 2004-04-20 2008-07-02 덴드리틱 나노테크놀로지즈, 인크. 증폭성 및 내부 관능성이 증진된 수지상 중합체
US7985424B2 (en) 2004-04-20 2011-07-26 Dendritic Nanotechnologies Inc. Dendritic polymers with enhanced amplification and interior functionality
JP2008545621A (ja) * 2005-04-20 2008-12-18 デンドリティック ナノテクノロジーズ，インコーポレイテッド 強化された拡大性と内部官能基性をもった樹枝状ポリマー
EP2207570A2 (de) * 2007-09-14 2010-07-21 Nitto Denko Corporation Arzneimittelträger
EP2133064A1 (de) * 2008-06-10 2009-12-16 3M Innovative Properties Company Initiatorsystem mit einem Diarylalkylamin-Derivat, härtbare Zusammensetzung und deren Verwendung
US8841382B2 (en) * 2010-09-01 2014-09-23 Basf Se Hyperbranched polyethers/dendrimers for solubilzation of sparingly soluble active ingredients

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507466A (en) * 1983-01-07 1985-03-26 The Dow Chemical Corporation Dense star polymers having core, core branches, terminal groups
US4737550A (en) * 1983-01-07 1988-04-12 The Dow Chemical Company Bridged dense star polymers
US4568737A (en) * 1983-01-07 1986-02-04 The Dow Chemical Company Dense star polymers and dendrimers
US4587329A (en) * 1984-08-17 1986-05-06 The Dow Chemical Company Dense star polymers having two dimensional molecular diameter
US4694064A (en) * 1986-02-28 1987-09-15 The Dow Chemical Company Rod-shaped dendrimer
US4857599A (en) * 1988-02-08 1989-08-15 The Dow Chemical Company Modified dense star polymers
US5041516A (en) * 1989-06-21 1991-08-20 Cornell Research Foundation, Inc. Dendritic molecules and method of production
US5530092A (en) * 1992-01-13 1996-06-25 Dsm N.V. Dendritic macromolecule and the preparation thereof
IT1270994B (it) * 1994-03-18 1997-05-26 Bracco Spa Macromolecole ramificate a struttura poliossialchilica e loro usi
IT1277596B1 (it) * 1995-09-15 1997-11-11 Bracco Spa Composti macromolecolari di tipo dendrimerico

Also Published As

Publication number Publication date
ITMI951929A0 (it) 1995-09-15
KR19990044595A (ko) 1999-06-25
EP0850262B1 (de) 2001-05-23
AU6988196A (en) 1997-04-01
US5807971A (en) 1998-09-15
CA2231840A1 (en) 1997-03-20
ATE201425T1 (de) 2001-06-15
ITMI951929A1 (it) 1997-03-15
ZA967759B (en) 1998-03-13
US5994495A (en) 1999-11-30
EP0850262A1 (de) 1998-07-01
DE69612987D1 (de) 2001-06-28
IT1277596B1 (it) 1997-11-11
NO315658B1 (no) 2003-10-06
AU717922B2 (en) 2000-04-06
NO981092D0 (no) 1998-03-12
WO1997010281A1 (en) 1997-03-20
JPH11514396A (ja) 1999-12-07
NO981092L (no) 1998-03-12

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BRACCO IMAGING S.P.A., MAILAND/MILANO, IT

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee