ATE196083T1 - Verwendung von ferrioxamin-b zur behandlung septischen schocks - Google Patents
Verwendung von ferrioxamin-b zur behandlung septischen schocksInfo
- Publication number
- ATE196083T1 ATE196083T1 AT94914464T AT94914464T ATE196083T1 AT E196083 T1 ATE196083 T1 AT E196083T1 AT 94914464 T AT94914464 T AT 94914464T AT 94914464 T AT94914464 T AT 94914464T AT E196083 T1 ATE196083 T1 AT E196083T1
- Authority
- AT
- Austria
- Prior art keywords
- septic shock
- ferrioxamine
- treating septic
- treatment
- disclosed
- Prior art date
Links
- 206010040070 Septic Shock Diseases 0.000 title abstract 2
- 230000036303 septic shock Effects 0.000 title abstract 2
- SRMBQCVUAVULDJ-UHFFFAOYSA-N ferrioxamine b Chemical compound [Fe+3].CC(=O)N([O-])CCCCCNC(=O)CCC(=O)N([O-])CCCCCNC(=O)CCC(=O)N([O-])CCCCCN SRMBQCVUAVULDJ-UHFFFAOYSA-N 0.000 title 1
- 229910052723 transition metal Inorganic materials 0.000 abstract 2
- 150000003624 transition metals Chemical class 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 230000036543 hypotension Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/30—Copper compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/315—Zinc compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Removal Of Specific Substances (AREA)
- Treatment Of Sludge (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Registering, Tensioning, Guiding Webs, And Rollers Therefor (AREA)
- Gas Separation By Absorption (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939309387A GB9309387D0 (en) | 1993-05-06 | 1993-05-06 | Nitric oxide scavengers |
| PCT/GB1994/000967 WO1994026263A2 (en) | 1993-05-06 | 1994-05-05 | Use of a transition metal complex for the treatment of septic shock |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE196083T1 true ATE196083T1 (de) | 2000-09-15 |
Family
ID=10735068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94914464T ATE196083T1 (de) | 1993-05-06 | 1994-05-05 | Verwendung von ferrioxamin-b zur behandlung septischen schocks |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6465511B1 (de) |
| EP (1) | EP0697864B1 (de) |
| JP (1) | JP3844489B2 (de) |
| AT (1) | ATE196083T1 (de) |
| AU (1) | AU6682594A (de) |
| CA (1) | CA2162154C (de) |
| DE (1) | DE69425820T2 (de) |
| GB (1) | GB9309387D0 (de) |
| WO (1) | WO1994026263A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9309387D0 (en) | 1993-05-06 | 1993-06-16 | Wellcome Found | Nitric oxide scavengers |
| US6245758B1 (en) | 1994-05-13 | 2001-06-12 | Michael K. Stern | Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor |
| WO1995031197A1 (en) * | 1994-05-13 | 1995-11-23 | Monsanto Company | Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor |
| BR9915174A (pt) * | 1998-11-09 | 2001-11-06 | Ira Jay Newman | Complexo de prata iÈnica |
| AUPP784998A0 (en) * | 1998-12-21 | 1999-01-21 | Ghadiminejad, Iraj | A low molecular weigh, non-proteinaceous compound that inhibits mitogen induced cytokine production |
| US20040101488A1 (en) * | 2000-03-24 | 2004-05-27 | Balaram Ghosh | Method for the prevention of septic shock lethality using curcumin |
| FR2825920B1 (fr) * | 2001-06-15 | 2006-04-28 | Oreal | Desferal comme inhibiteur de no-synthase et utilisations |
| WO2003073997A2 (en) * | 2002-03-01 | 2003-09-12 | Luis Molina | Treatment of septic shock |
| CN100446776C (zh) * | 2003-02-20 | 2008-12-31 | 席堤克株式会社 | 过氧化物阴离子分解剂 |
| US20050220862A1 (en) * | 2004-03-31 | 2005-10-06 | Bernstein Joel E | Compositions with reduced hepatotoxicity |
| BG65787B1 (bg) | 2004-11-23 | 2009-11-30 | Чавдар ВАСИЛЕВ | Средство за повишаване на антиген-свързващата активност на имуноглобулинови препарати |
| US8214310B2 (en) | 2005-05-18 | 2012-07-03 | International Business Machines Corporation | Cross descriptor learning system, method and program product therefor |
| BR112012003447A2 (pt) * | 2009-08-19 | 2018-03-20 | Hadasit Med Res Service | método de prevenir, tratar, melhorar ou inibir uma desordem relacionada ao sistema imunológico, uso de uma quantidade terapeuticamente eficaz de pelo menos um complexo de metal desferrioxamina (complexo de metal-dfo), composição e composição farmacêutica. |
| WO2014008273A2 (en) * | 2012-07-03 | 2014-01-09 | Jay Pravda | Methods for treating, diagnosing and/or monitoring progression of oxo associated states |
| US9382151B2 (en) | 2014-01-31 | 2016-07-05 | Corning Incorporated | Low expansion silica-titania articles with a Tzc gradient by compositional variation |
| US12053511B2 (en) | 2016-11-30 | 2024-08-06 | Board Or Regents, The University Of Texas System | Cystatin C and Cystatin 9 to treat gut inflammation caused by thermal injury |
| US20250127740A1 (en) * | 2021-11-09 | 2025-04-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Composition containing 3-hydroxyanthranilic acid and compounds that alter iron homeostasis and method of its use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2891854A (en) * | 1954-06-16 | 1959-06-23 | Geigy Chem Corp | Chelated iron compositions |
| US4451442A (en) | 1982-06-21 | 1984-05-29 | The Dow Chemical Company | Removal of hydrogen sulfide from fluid streams with minimum production of solids |
| US5223538A (en) | 1987-03-31 | 1993-06-29 | Duke University | Superoxide dismutase mimic |
| US5227405A (en) | 1987-03-31 | 1993-07-13 | Duke University | Superoxide dismutase mimic |
| DE3842143A1 (de) * | 1988-12-15 | 1990-06-21 | Nitsche Dietrich | Verwendung von transferrin zur endotoxinneutralisation |
| US5296466A (en) | 1992-02-19 | 1994-03-22 | Board Of Regents, The University Of Texas System | Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein |
| GB9309387D0 (en) | 1993-05-06 | 1993-06-16 | Wellcome Found | Nitric oxide scavengers |
-
1993
- 1993-05-06 GB GB939309387A patent/GB9309387D0/en active Pending
-
1994
- 1994-05-05 EP EP94914464A patent/EP0697864B1/de not_active Expired - Lifetime
- 1994-05-05 DE DE69425820T patent/DE69425820T2/de not_active Expired - Fee Related
- 1994-05-05 WO PCT/GB1994/000967 patent/WO1994026263A2/en not_active Ceased
- 1994-05-05 AT AT94914464T patent/ATE196083T1/de active
- 1994-05-05 CA CA002162154A patent/CA2162154C/en not_active Expired - Fee Related
- 1994-05-05 JP JP52511694A patent/JP3844489B2/ja not_active Expired - Fee Related
- 1994-05-05 AU AU66825/94A patent/AU6682594A/en not_active Abandoned
-
1997
- 1997-08-27 US US08/921,997 patent/US6465511B1/en not_active Expired - Fee Related
-
2001
- 2001-10-05 US US09/971,079 patent/US20020091113A1/en not_active Abandoned
-
2002
- 2002-08-06 US US10/212,906 patent/US7022734B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB9309387D0 (en) | 1993-06-16 |
| CA2162154A1 (en) | 1994-11-24 |
| US20030008856A1 (en) | 2003-01-09 |
| WO1994026263A3 (en) | 1995-01-05 |
| EP0697864B1 (de) | 2000-09-06 |
| JPH08510449A (ja) | 1996-11-05 |
| AU6682594A (en) | 1994-12-12 |
| US6465511B1 (en) | 2002-10-15 |
| DE69425820D1 (de) | 2000-10-12 |
| JP3844489B2 (ja) | 2006-11-15 |
| US20020091113A1 (en) | 2002-07-11 |
| WO1994026263A2 (en) | 1994-11-24 |
| DE69425820T2 (de) | 2001-03-22 |
| US7022734B2 (en) | 2006-04-04 |
| CA2162154C (en) | 2007-03-20 |
| EP0697864A1 (de) | 1996-02-28 |
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