DE69425820D1 - Verwendung von ferrioxamin-b zur behandlung septischen schocks - Google Patents

Verwendung von ferrioxamin-b zur behandlung septischen schocks

Info

Publication number
DE69425820D1
DE69425820D1 DE69425820T DE69425820T DE69425820D1 DE 69425820 D1 DE69425820 D1 DE 69425820D1 DE 69425820 T DE69425820 T DE 69425820T DE 69425820 T DE69425820 T DE 69425820T DE 69425820 D1 DE69425820 D1 DE 69425820D1
Authority
DE
Germany
Prior art keywords
treatment
ferrioxamine
septic shocks
disclosed
transition metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69425820T
Other languages
English (en)
Other versions
DE69425820T2 (de
Inventor
Wieslaw Mieczyslaw Kazmierski
Luis Molina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molichem Medicines Inc
Original Assignee
Molichem Medicines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molichem Medicines Inc filed Critical Molichem Medicines Inc
Publication of DE69425820D1 publication Critical patent/DE69425820D1/de
Application granted granted Critical
Publication of DE69425820T2 publication Critical patent/DE69425820T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/295Iron group metal compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/30Copper compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/315Zinc compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Removal Of Specific Substances (AREA)
  • Treatment Of Sludge (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Registering, Tensioning, Guiding Webs, And Rollers Therefor (AREA)
  • Gas Separation By Absorption (AREA)
DE69425820T 1993-05-06 1994-05-05 Verwendung von ferrioxamin-b zur behandlung septischen schocks Expired - Fee Related DE69425820T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939309387A GB9309387D0 (en) 1993-05-06 1993-05-06 Nitric oxide scavengers
PCT/GB1994/000967 WO1994026263A2 (en) 1993-05-06 1994-05-05 Use of a transition metal complex for the treatment of septic shock

Publications (2)

Publication Number Publication Date
DE69425820D1 true DE69425820D1 (de) 2000-10-12
DE69425820T2 DE69425820T2 (de) 2001-03-22

Family

ID=10735068

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69425820T Expired - Fee Related DE69425820T2 (de) 1993-05-06 1994-05-05 Verwendung von ferrioxamin-b zur behandlung septischen schocks

Country Status (9)

Country Link
US (3) US6465511B1 (de)
EP (1) EP0697864B1 (de)
JP (1) JP3844489B2 (de)
AT (1) ATE196083T1 (de)
AU (1) AU6682594A (de)
CA (1) CA2162154C (de)
DE (1) DE69425820T2 (de)
GB (1) GB9309387D0 (de)
WO (1) WO1994026263A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9309387D0 (en) 1993-05-06 1993-06-16 Wellcome Found Nitric oxide scavengers
US6245758B1 (en) 1994-05-13 2001-06-12 Michael K. Stern Methods of use for peroxynitrite decomposition catalysts, pharmaceutical compositions therefor
NZ285648A (en) * 1994-05-13 1999-08-30 Monsanto Co Use of a metal complex as a metal peroxynitrite decomposition catalyst to treat diseases which are affected by accelerated decomposition of peroxynitrite
AU776212B2 (en) * 1998-11-09 2004-09-02 Ira Jay Newman Ionic silver complex
AUPP784998A0 (en) * 1998-12-21 1999-01-21 Ghadiminejad, Iraj A low molecular weigh, non-proteinaceous compound that inhibits mitogen induced cytokine production
US20040101488A1 (en) * 2000-03-24 2004-05-27 Balaram Ghosh Method for the prevention of septic shock lethality using curcumin
FR2825920B1 (fr) * 2001-06-15 2006-04-28 Oreal Desferal comme inhibiteur de no-synthase et utilisations
WO2003073997A2 (en) * 2002-03-01 2003-09-12 Luis Molina Treatment of septic shock
ZA200507289B (en) * 2003-02-20 2006-12-27 Shetech Co Ltd Medical Drug Containing Fine Particle of Noble Metal
US20050220862A1 (en) 2004-03-31 2005-10-06 Bernstein Joel E Compositions with reduced hepatotoxicity
BG65787B1 (bg) 2004-11-23 2009-11-30 Чавдар ВАСИЛЕВ Средство за повишаване на антиген-свързващата активност на имуноглобулинови препарати
US8214310B2 (en) 2005-05-18 2012-07-03 International Business Machines Corporation Cross descriptor learning system, method and program product therefor
US8975294B2 (en) * 2009-08-19 2015-03-10 Hadasit Medical Research Services And Development Ltd. Desferrioxamine-metal complexes for the treatment of immune-related disorders
CN104582490A (zh) * 2012-07-03 2015-04-29 杰·普拉夫达 治疗、诊断和/或监测氧相关疾病进展的方法
US9382151B2 (en) 2014-01-31 2016-07-05 Corning Incorporated Low expansion silica-titania articles with a Tzc gradient by compositional variation
WO2023086364A1 (en) * 2021-11-09 2023-05-19 Arizona Board Of Regents On Behalf Of The University Of Arizona Composition containing 3-hydroxyanthranilic acid and compounds that alter iron homeostasis and method of its use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891854A (en) * 1954-06-16 1959-06-23 Geigy Chem Corp Chelated iron compositions
US4451442A (en) 1982-06-21 1984-05-29 The Dow Chemical Company Removal of hydrogen sulfide from fluid streams with minimum production of solids
US5223538A (en) 1987-03-31 1993-06-29 Duke University Superoxide dismutase mimic
US5227405A (en) 1987-03-31 1993-07-13 Duke University Superoxide dismutase mimic
DE3842143A1 (de) * 1988-12-15 1990-06-21 Nitsche Dietrich Verwendung von transferrin zur endotoxinneutralisation
US5296466A (en) * 1992-02-19 1994-03-22 Board Of Regents, The University Of Texas System Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein
GB9309387D0 (en) 1993-05-06 1993-06-16 Wellcome Found Nitric oxide scavengers

Also Published As

Publication number Publication date
EP0697864A1 (de) 1996-02-28
EP0697864B1 (de) 2000-09-06
JP3844489B2 (ja) 2006-11-15
GB9309387D0 (en) 1993-06-16
WO1994026263A3 (en) 1995-01-05
JPH08510449A (ja) 1996-11-05
CA2162154C (en) 2007-03-20
US20030008856A1 (en) 2003-01-09
AU6682594A (en) 1994-12-12
US7022734B2 (en) 2006-04-04
ATE196083T1 (de) 2000-09-15
WO1994026263A2 (en) 1994-11-24
US20020091113A1 (en) 2002-07-11
CA2162154A1 (en) 1994-11-24
DE69425820T2 (de) 2001-03-22
US6465511B1 (en) 2002-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee