BR122017023795B8 - método para preparação de composição farmacêutica - Google Patents

método para preparação de composição farmacêutica

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Publication number
BR122017023795B8
BR122017023795B8 BR122017023795A BR122017023795A BR122017023795B8 BR 122017023795 B8 BR122017023795 B8 BR 122017023795B8 BR 122017023795 A BR122017023795 A BR 122017023795A BR 122017023795 A BR122017023795 A BR 122017023795A BR 122017023795 B8 BR122017023795 B8 BR 122017023795B8
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BR
Brazil
Prior art keywords
disorder
age
mental
pain
depression
Prior art date
Application number
BR122017023795A
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English (en)
Other versions
BR122017023795B1 (pt
Inventor
Smith Brian
Smith Jeffrey
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Eisai Inc
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Family has litigation
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Application filed by Eisai Inc filed Critical Eisai Inc
Publication of BR122017023795B1 publication Critical patent/BR122017023795B1/pt
Publication of BR122017023795B8 publication Critical patent/BR122017023795B8/pt

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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Abstract

a presente invenção refere-se a novos compostos de fórmula (i) que atuam como moduladores do receptor de 5ht2c. estes compostos são úteis em composições farmacêuticas cujo uso inclui tratamento de obesidade.
BR122017023795A 2002-04-12 2003-04-11 método para preparação de composição farmacêutica BR122017023795B8 (pt)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US37205802P 2002-04-12 2002-04-12
US60/372,058 2002-04-12
US40549502P 2002-08-23 2002-08-23
US60/405,495 2002-08-23
US43460702P 2002-12-18 2002-12-18
US60/434,607 2002-12-18
US10/410,991 2003-04-10
US10/410,991 US6953787B2 (en) 2002-04-12 2003-04-10 5HT2C receptor modulators
BRPI0309303 2003-04-11
PCT/US2003/011076 WO2003086306A2 (en) 2002-04-12 2003-04-11 5ht2c receptor modulators

Publications (2)

Publication Number Publication Date
BR122017023795B1 BR122017023795B1 (pt) 2020-11-24
BR122017023795B8 true BR122017023795B8 (pt) 2021-07-27

Family

ID=29255581

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0309303A BRPI0309303B8 (pt) 2002-04-12 2003-04-11 compostos moduladores de receptores de 5ht2c, composição farmacêutica, e uso dos referidos compostos
BR122017023795A BR122017023795B8 (pt) 2002-04-12 2003-04-11 método para preparação de composição farmacêutica

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI0309303A BRPI0309303B8 (pt) 2002-04-12 2003-04-11 compostos moduladores de receptores de 5ht2c, composição farmacêutica, e uso dos referidos compostos

Country Status (29)

Country Link
US (11) US6953787B2 (pt)
EP (4) EP2363394A1 (pt)
JP (5) JP4155926B2 (pt)
KR (3) KR100908166B1 (pt)
CN (5) CN101486677B (pt)
AT (1) ATE294781T1 (pt)
AU (1) AU2003221866B2 (pt)
BR (2) BRPI0309303B8 (pt)
CA (1) CA2481723C (pt)
CR (2) CR7503A (pt)
DE (1) DE60300610T2 (pt)
DK (1) DK1411881T3 (pt)
ES (2) ES2670568T3 (pt)
GE (1) GEP20074197B (pt)
HK (1) HK1064095A1 (pt)
IL (1) IL164162A0 (pt)
IS (1) IS2134B (pt)
MX (1) MXPA04009965A (pt)
MY (1) MY141476A (pt)
NO (1) NO323528B1 (pt)
NZ (1) NZ535381A (pt)
PL (4) PL211314B1 (pt)
PT (1) PT1411881E (pt)
RU (1) RU2317982C2 (pt)
SI (1) SI1411881T1 (pt)
TW (1) TWI252105B (pt)
UA (1) UA77788C2 (pt)
WO (1) WO2003086306A2 (pt)
ZA (1) ZA200408506B (pt)

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US7514422B2 (en) 2009-04-07
TWI252105B (en) 2006-04-01
PL211333B1 (pl) 2012-05-31
JP4155926B2 (ja) 2008-09-24
HK1064095A1 (en) 2005-01-21
NO20044928L (no) 2004-12-13
ES2242165T3 (es) 2005-11-01
CN101486678B (zh) 2015-09-09
US8546379B2 (en) 2013-10-01
TW200400037A (en) 2004-01-01
EP1411881A2 (en) 2004-04-28
IS2134B (is) 2006-08-15
JP5602116B2 (ja) 2014-10-08
KR100908166B1 (ko) 2009-07-16
NZ535381A (en) 2006-07-28
IL164162A0 (en) 2005-12-18
US20130012495A1 (en) 2013-01-10
WO2003086306A3 (en) 2004-02-19
JP2012006970A (ja) 2012-01-12
NO323528B1 (no) 2007-06-04
KR20080009340A (ko) 2008-01-28
US20130012498A1 (en) 2013-01-10
JP2009001584A (ja) 2009-01-08
JP4966929B2 (ja) 2012-07-04
US20150045552A1 (en) 2015-02-12
BRPI0309303B1 (pt) 2018-05-29
PL373464A1 (en) 2005-09-05
US8846906B2 (en) 2014-09-30
RU2317982C2 (ru) 2008-02-27
GEP20074197B (en) 2007-09-10
ZA200408506B (en) 2006-06-28
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US7977329B2 (en) 2011-07-12

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