CH498122A - Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates - Google Patents

Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Info

Publication number
CH498122A
CH498122A CH197668A CH197668A CH498122A CH 498122 A CH498122 A CH 498122A CH 197668 A CH197668 A CH 197668A CH 197668 A CH197668 A CH 197668A CH 498122 A CH498122 A CH 498122A
Authority
CH
Switzerland
Prior art keywords
preparation
new
tetrahydroazepine derivative
tetrahydroazepine
derivative
Prior art date
Application number
CH197668A
Other languages
English (en)
Inventor
Karl Dr Hoegerle
Ernst Dr Habicht
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Priority to CH197668A priority Critical patent/CH498122A/de
Priority to IL30458A priority patent/IL30458A/en
Priority to NL6811311A priority patent/NL6811311A/xx
Priority to DK383268AA priority patent/DK123526B/da
Priority to ES357247A priority patent/ES357247A1/es
Priority to DE19681795132 priority patent/DE1795132A1/de
Priority to AT797568A priority patent/AT277257B/de
Priority to GB38772/68A priority patent/GB1225053A/en
Priority to FR163036A priority patent/FR7915M/fr
Priority to FR1598948D priority patent/FR1598948A/fr
Priority to BE719631D priority patent/BE719631A/xx
Publication of CH498122A publication Critical patent/CH498122A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH197668A 1967-02-17 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates CH498122A (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (de) 1968-02-09 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates
IL30458A IL30458A (en) 1968-02-09 1968-07-29 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it
NL6811311A NL6811311A (de) 1968-02-09 1968-08-08
DK383268AA DK123526B (da) 1968-02-09 1968-08-08 Fremgangsmåde til fremstilling af 6-chlor-2,3,4,5-tetrahydro-1H-3-benzazepin eller syreadditionssalte deraf.
ES357247A ES357247A1 (es) 1968-02-09 1968-08-14 Procedimiento para la preparacion de un nuevo derivado de tetrahidroacepina.
DE19681795132 DE1795132A1 (de) 1968-02-09 1968-08-14 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates
AT797568A AT277257B (de) 1968-02-09 1968-08-14 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates sowie seiner Säureadditionssalze
GB38772/68A GB1225053A (en) 1968-02-09 1968-08-14 New tetrahydroazepine derivative, process for its production and compositions containing same
FR163036A FR7915M (de) 1967-02-17 1968-08-14
FR1598948D FR1598948A (de) 1968-02-09 1968-08-14
BE719631D BE719631A (de) 1968-02-09 1968-08-16

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH197668A CH498122A (de) 1968-02-09 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
CH498122A true CH498122A (de) 1970-10-31

Family

ID=4223010

Family Applications (1)

Application Number Title Priority Date Filing Date
CH197668A CH498122A (de) 1967-02-17 1968-02-09 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Country Status (10)

Country Link
AT (1) AT277257B (de)
BE (1) BE719631A (de)
CH (1) CH498122A (de)
DE (1) DE1795132A1 (de)
DK (1) DK123526B (de)
ES (1) ES357247A1 (de)
FR (1) FR1598948A (de)
GB (1) GB1225053A (de)
IL (1) IL30458A (de)
NL (1) NL6811311A (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2171879A1 (en) * 1972-02-14 1973-09-28 Pennwalt Corp 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc
US4160765A (en) * 1976-11-17 1979-07-10 Smithkline Corporation Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4197297A (en) * 1976-11-17 1980-04-08 Smithkline Corporation 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
CN1805939B (zh) 2003-06-17 2010-10-13 艾尼纳制药公司 用于治疗5ht2c受体相关病症的苯并氮杂卓衍生物
HUE028976T2 (en) 2003-06-17 2017-02-28 Arena Pharm Inc 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
TW200510324A (en) * 2003-08-11 2005-03-16 Lilly Co Eli 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist
DK1838677T3 (da) 2004-12-21 2010-01-11 Arena Pharm Inc Krystallinske former af (R)-8-chlor-1.methyl-2,3,4,5-tetrahydro-1H-3-benzazepinhydrochlorid
SI1833473T1 (sl) 2004-12-23 2010-01-29 Arena Pharm Inc Sestavki modulatorjev 5HT2C receptorjev in postopki uporabe
JP5199997B2 (ja) 2006-04-03 2013-05-15 アリーナ ファーマシューティカルズ， インコーポレイテッド ８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス
SG177128A1 (en) 2006-12-05 2012-01-30 Arena Pharm Inc Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
US8822727B2 (en) 2008-03-04 2014-09-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
EP2443080A2 (de) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Verfahren zur herstellung von 5-ht2c-rezeptoragonisten
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
CN103347523A (zh) 2010-09-01 2013-10-09 艾尼纳制药公司 向具有肾损伤的个体给药氯卡色林
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
EP2611782A1 (de) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Lorcaserin-salze mit optisch aktiven säuren
EP3485878A1 (de) 2010-09-01 2019-05-22 Arena Pharmaceuticals, Inc. Darreichungsformen von 5-ht2c-agonisten, die nützlich für gewichtskontrolle sind
MY181736A (en) 2012-10-09 2021-01-05 Arena Pharm Inc Method of weight management

Also Published As

Publication number Publication date
DK123526B (da) 1972-07-03
IL30458A0 (en) 1968-09-26
IL30458A (en) 1972-03-28
ES357247A1 (es) 1970-03-01
AT277257B (de) 1969-12-29
GB1225053A (en) 1971-03-17
FR1598948A (de) 1970-07-15
BE719631A (de) 1969-02-17
DE1795132A1 (de) 1972-01-05
NL6811311A (de) 1969-08-12

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Legal Events

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PL Patent ceased