CH498122A - Process for the preparation of a new tetrahydroazepine derivative - Google Patents
Process for the preparation of a new tetrahydroazepine derivativeInfo
- Publication number
- CH498122A CH498122A CH197668A CH197668A CH498122A CH 498122 A CH498122 A CH 498122A CH 197668 A CH197668 A CH 197668A CH 197668 A CH197668 A CH 197668A CH 498122 A CH498122 A CH 498122A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- new
- tetrahydroazepine derivative
- tetrahydroazepine
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH197668A CH498122A (en) | 1968-02-09 | 1968-02-09 | Process for the preparation of a new tetrahydroazepine derivative |
IL30458A IL30458A (en) | 1968-02-09 | 1968-07-29 | 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it |
NL6811311A NL6811311A (en) | 1968-02-09 | 1968-08-08 | |
DK383268AA DK123526B (en) | 1968-02-09 | 1968-08-08 | Process for the preparation of 6-chloro-2,3,4,5-tetrahydro-1H-3-benzazepine or acid addition salts thereof. |
DE19681795132 DE1795132A1 (en) | 1968-02-09 | 1968-08-14 | Process for the preparation of a new tetrahydroazepine derivative |
ES357247A ES357247A1 (en) | 1968-02-09 | 1968-08-14 | New tetrahydroazepine derivative, process for its production and compositions containing same |
GB38772/68A GB1225053A (en) | 1968-02-09 | 1968-08-14 | New tetrahydroazepine derivative, process for its production and compositions containing same |
AT797568A AT277257B (en) | 1968-02-09 | 1968-08-14 | Process for the preparation of a new tetrahydroazepine derivative and its acid addition salts |
FR1598948D FR1598948A (en) | 1968-02-09 | 1968-08-14 | |
FR163036A FR7915M (en) | 1967-02-17 | 1968-08-14 | |
BE719631D BE719631A (en) | 1968-02-09 | 1968-08-16 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH197668A CH498122A (en) | 1968-02-09 | 1968-02-09 | Process for the preparation of a new tetrahydroazepine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
CH498122A true CH498122A (en) | 1970-10-31 |
Family
ID=4223010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH197668A CH498122A (en) | 1967-02-17 | 1968-02-09 | Process for the preparation of a new tetrahydroazepine derivative |
Country Status (10)
Country | Link |
---|---|
AT (1) | AT277257B (en) |
BE (1) | BE719631A (en) |
CH (1) | CH498122A (en) |
DE (1) | DE1795132A1 (en) |
DK (1) | DK123526B (en) |
ES (1) | ES357247A1 (en) |
FR (1) | FR1598948A (en) |
GB (1) | GB1225053A (en) |
IL (1) | IL30458A (en) |
NL (1) | NL6811311A (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2171879A1 (en) * | 1972-02-14 | 1973-09-28 | Pennwalt Corp | 1,2,4,5-tetrahydro-3h-3-benzazepines - analgesics narcotic antagonists, antihistamines etc |
US4160765A (en) * | 1976-11-17 | 1979-07-10 | Smithkline Corporation | Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds |
US4197297A (en) * | 1976-11-17 | 1980-04-08 | Smithkline Corporation | 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines |
US4171359A (en) * | 1978-04-12 | 1979-10-16 | Smithkline Corporation | Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
CN1805938B (en) | 2003-06-17 | 2010-06-16 | 艾尼纳制药公司 | Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases |
EP2332919A3 (en) | 2003-06-17 | 2011-10-19 | Arena Pharmaceuticals, Inc. | Processes for preparing 3-benzazepines |
TW200510324A (en) * | 2003-08-11 | 2005-03-16 | Lilly Co Eli | 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist |
US8168624B2 (en) | 2004-12-21 | 2012-05-01 | Arena Pharmaceuticals, Inc. | Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
NZ555482A (en) | 2004-12-23 | 2011-01-28 | Arena Pharm Inc | Compositions comprising a 5HT2C receptor modulator and 2-methylamphetamine and methods of use |
CN101466684B (en) | 2006-04-03 | 2012-06-20 | 艾尼纳制药公司 | Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates related thereto |
US8299241B2 (en) | 2006-12-05 | 2012-10-30 | Arena Pharmaceuticals, Inc. | Processes for preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates thereof |
JP5491421B2 (en) | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ, インコーポレイテッド | Process for the preparation of intermediates related to the 5-HT2C agonist (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
EP2443080A2 (en) | 2009-06-18 | 2012-04-25 | Arena Pharmaceuticals, Inc. | Process for the preparation of 5-ht2c receptor agonists |
WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
EP2939677A1 (en) | 2010-09-01 | 2015-11-04 | Arena Pharmaceuticals, Inc. | Administration of lorcaserin to indviduals with renal impairment |
CN103189359A (en) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | Salts of lorcaserin with optically active acids |
ES2704455T3 (en) | 2010-09-01 | 2019-03-18 | Arena Pharm Inc | Pharmaceutical forms of modified release of 5-HT2C agonists useful for weight management |
EP2611433A2 (en) | 2010-09-01 | 2013-07-10 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
MY181736A (en) | 2012-10-09 | 2021-01-05 | Arena Pharm Inc | Method of weight management |
-
1968
- 1968-02-09 CH CH197668A patent/CH498122A/en not_active IP Right Cessation
- 1968-07-29 IL IL30458A patent/IL30458A/en unknown
- 1968-08-08 NL NL6811311A patent/NL6811311A/xx unknown
- 1968-08-08 DK DK383268AA patent/DK123526B/en unknown
- 1968-08-14 AT AT797568A patent/AT277257B/en not_active IP Right Cessation
- 1968-08-14 DE DE19681795132 patent/DE1795132A1/en active Pending
- 1968-08-14 GB GB38772/68A patent/GB1225053A/en not_active Expired
- 1968-08-14 ES ES357247A patent/ES357247A1/en not_active Expired
- 1968-08-14 FR FR1598948D patent/FR1598948A/fr not_active Expired
- 1968-08-16 BE BE719631D patent/BE719631A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE1795132A1 (en) | 1972-01-05 |
BE719631A (en) | 1969-02-17 |
ES357247A1 (en) | 1970-03-01 |
DK123526B (en) | 1972-07-03 |
FR1598948A (en) | 1970-07-15 |
IL30458A (en) | 1972-03-28 |
IL30458A0 (en) | 1968-09-26 |
NL6811311A (en) | 1969-08-12 |
AT277257B (en) | 1969-12-29 |
GB1225053A (en) | 1971-03-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |