IL30458A0 - A new tetrahydroazepine derivative its preparation and compositions containing it - Google Patents
A new tetrahydroazepine derivative its preparation and compositions containing itInfo
- Publication number
- IL30458A0 IL30458A0 IL30458A IL3045868A IL30458A0 IL 30458 A0 IL30458 A0 IL 30458A0 IL 30458 A IL30458 A IL 30458A IL 3045868 A IL3045868 A IL 3045868A IL 30458 A0 IL30458 A0 IL 30458A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- new
- compositions containing
- tetrahydroazepine derivative
- tetrahydroazepine
- Prior art date
Links
- SCEIUGQQBYRBPP-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1h-azepine Chemical class C1CCC=CNC1 SCEIUGQQBYRBPP-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH197668A CH498122A (en) | 1968-02-09 | 1968-02-09 | Process for the preparation of a new tetrahydroazepine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL30458A0 true IL30458A0 (en) | 1968-09-26 |
| IL30458A IL30458A (en) | 1972-03-28 |
Family
ID=4223010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL30458A IL30458A (en) | 1968-02-09 | 1968-07-29 | 6-chloro-2,3,4,5-tetrahydro-1h-3-benzazepine,its preparation and compositions containing it |
Country Status (10)
| Country | Link |
|---|---|
| AT (1) | AT277257B (en) |
| BE (1) | BE719631A (en) |
| CH (1) | CH498122A (en) |
| DE (1) | DE1795132A1 (en) |
| DK (1) | DK123526B (en) |
| ES (1) | ES357247A1 (en) |
| FR (1) | FR1598948A (en) |
| GB (1) | GB1225053A (en) |
| IL (1) | IL30458A (en) |
| NL (1) | NL6811311A (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2207430C3 (en) * | 1972-02-14 | 1982-05-13 | Pennwalt Corp., 19102 Philadelphia, Pa. | 1,2,4,5-Tetrahydro-3H-3-benzazepine, a process for their preparation and a pharmaceutical agent containing them |
| US4160765A (en) * | 1976-11-17 | 1979-07-10 | Smithkline Corporation | Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds |
| US4197297A (en) * | 1976-11-17 | 1980-04-08 | Smithkline Corporation | 6-Halo-7,8-dihydroxy-1-(hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US4171359A (en) * | 1978-04-12 | 1979-10-16 | Smithkline Corporation | Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| SI2332921T1 (en) | 2003-06-17 | 2016-06-30 | Arena Pharmaceuticals, Inc. | 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride |
| US7704993B2 (en) | 2003-06-17 | 2010-04-27 | Arena Pharmaceuticals, Inc. | Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases |
| TW200510324A (en) * | 2003-08-11 | 2005-03-16 | Lilly Co Eli | 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist |
| CA2589988C (en) | 2004-12-21 | 2017-02-14 | Arena Pharmaceuticals, Inc. | Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride |
| PT1833473E (en) | 2004-12-23 | 2009-12-17 | Arena Pharm Inc | 5ht2c receptor modulator compositions and methods of use |
| EP2518053A1 (en) | 2006-04-03 | 2012-10-31 | Arena Pharmaceuticals, Inc. | Process for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine |
| EP2099743B1 (en) | 2006-12-05 | 2014-08-27 | Arena Pharmaceuticals, Inc. | Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof |
| JP5491421B2 (en) | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ, インコーポレイテッド | Process for the preparation of intermediates related to the 5-HT2C agonist (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
| CN102648170A (en) | 2009-06-18 | 2012-08-22 | 艾尼纳制药公司 | Processes for the preparation of 5-HT2C receptor agonists |
| WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| MX2013002422A (en) | 2010-09-01 | 2013-05-17 | Arena Pharm Inc | Salts of lorcaserin with optically active acids. |
| WO2012030957A2 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
| CN103347523A (en) | 2010-09-01 | 2013-10-09 | 艾尼纳制药公司 | Administration of lorcaserin to individual with renal impairment |
| KR20180118801A (en) | 2010-09-01 | 2018-10-31 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
| WO2014058441A1 (en) | 2012-10-09 | 2014-04-17 | Arena Pharmaceuticals, Inc. | Method of weight management |
-
1968
- 1968-02-09 CH CH197668A patent/CH498122A/en not_active IP Right Cessation
- 1968-07-29 IL IL30458A patent/IL30458A/en unknown
- 1968-08-08 DK DK383268AA patent/DK123526B/en unknown
- 1968-08-08 NL NL6811311A patent/NL6811311A/xx unknown
- 1968-08-14 FR FR1598948D patent/FR1598948A/fr not_active Expired
- 1968-08-14 DE DE19681795132 patent/DE1795132A1/en active Pending
- 1968-08-14 AT AT797568A patent/AT277257B/en not_active IP Right Cessation
- 1968-08-14 ES ES357247A patent/ES357247A1/en not_active Expired
- 1968-08-14 GB GB38772/68A patent/GB1225053A/en not_active Expired
- 1968-08-16 BE BE719631D patent/BE719631A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT277257B (en) | 1969-12-29 |
| BE719631A (en) | 1969-02-17 |
| NL6811311A (en) | 1969-08-12 |
| CH498122A (en) | 1970-10-31 |
| DE1795132A1 (en) | 1972-01-05 |
| FR1598948A (en) | 1970-07-15 |
| ES357247A1 (en) | 1970-03-01 |
| GB1225053A (en) | 1971-03-17 |
| DK123526B (en) | 1972-07-03 |
| IL30458A (en) | 1972-03-28 |
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