CH488705A - Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates - Google Patents

Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Info

Publication number
CH488705A
CH488705A CH1167167A CH1167167A CH488705A CH 488705 A CH488705 A CH 488705A CH 1167167 A CH1167167 A CH 1167167A CH 1167167 A CH1167167 A CH 1167167A CH 488705 A CH488705 A CH 488705A
Authority
CH
Switzerland
Prior art keywords
preparation
new
tetrahydroazepine derivative
tetrahydroazepine
derivative
Prior art date
Application number
CH1167167A
Other languages
English (en)
Inventor
Karl Dr Hoegerle
Ernst Dr Habicht
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH238667A priority Critical patent/CH481110A/de
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Priority to CH1167167A priority patent/CH488705A/de
Priority to US705612A priority patent/US3652543A/en
Priority to GB7601/68A priority patent/GB1221324A/en
Priority to GB7600/68A priority patent/GB1222397A/en
Priority to ES350574A priority patent/ES350574A1/es
Priority to DE19681695124 priority patent/DE1695124A1/de
Priority to NL6802257A priority patent/NL6802257A/xx
Priority to NO0598/68A priority patent/NO124369B/no
Priority to FR1560654D priority patent/FR1560654A/fr
Priority to IL29485A priority patent/IL29485A/xx
Priority to DK63068AA priority patent/DK115473B/da
Priority to SE2047/68A priority patent/SE342043B/xx
Priority to BE710872D priority patent/BE710872A/xx
Priority to AT148868A priority patent/AT275533B/de
Priority to FR1561479D priority patent/FR1561479A/fr
Priority to DE19681668915 priority patent/DE1668915A1/de
Priority to FR163036A priority patent/FR7915M/fr
Publication of CH488705A publication Critical patent/CH488705A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Drawers Of Furniture (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CH1167167A 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates CH488705A (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH1167167A CH488705A (de) 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates
US705612A US3652543A (en) 1967-02-17 1968-02-15 Process for the production of 1 2 4 5-tetrahydro-3-azepines
FR1560654D FR1560654A (de) 1967-02-17 1968-02-16
IL29485A IL29485A (en) 1967-02-17 1968-02-16 Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines
ES350574A ES350574A1 (es) 1967-02-17 1968-02-16 Procedimiento para la preparacion de 2,3,4,5-tetrahidro-1h-3-benzazepinas.
DE19681695124 DE1695124A1 (de) 1967-02-17 1968-02-16 Verfahren zur Herstellung von Tetrahydroazepinderivaten
NL6802257A NL6802257A (de) 1967-02-17 1968-02-16
NO0598/68A NO124369B (de) 1967-02-17 1968-02-16
GB7601/68A GB1221324A (en) 1967-02-17 1968-02-16 New processes for the production of benzazepine derivatives
GB7600/68A GB1222397A (en) 1967-02-17 1968-02-16 Process for the preparation of phenethylamine salts
DK63068AA DK115473B (da) 1967-02-17 1968-02-16 Fremgangsmåde til fremstilling af 2,3,4,5-tetrahydro-1H-3-benzazepiner eller syreadditionssalte deraf.
SE2047/68A SE342043B (de) 1967-02-17 1968-02-16
BE710872D BE710872A (de) 1967-02-17 1968-02-16
AT148868A AT275533B (de) 1967-02-17 1968-02-16 Verfahren zur Herstellung von 2,3,4,5-Tetrahydro-1H-3-benzazepinen sowie ihrer Additionssalze mit anorganischen oder organischen Säuren
FR1561479D FR1561479A (de) 1967-02-17 1968-02-16
DE19681668915 DE1668915A1 (de) 1967-02-17 1968-02-16 Neue Phenaethylamin-Salze und Verfahren zu deren Herstellung
FR163036A FR7915M (de) 1967-02-17 1968-08-14

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH1167167A CH488705A (de) 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
CH488705A true CH488705A (de) 1970-04-15

Family

ID=25690322

Family Applications (2)

Application Number Title Priority Date Filing Date
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH1167167A CH488705A (de) 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen

Country Status (13)

Country Link
US (1) US3652543A (de)
AT (1) AT275533B (de)
BE (1) BE710872A (de)
CH (2) CH481110A (de)
DE (2) DE1695124A1 (de)
DK (1) DK115473B (de)
ES (1) ES350574A1 (de)
FR (2) FR1561479A (de)
GB (2) GB1222397A (de)
IL (1) IL29485A (de)
NL (1) NL6802257A (de)
NO (1) NO124369B (de)
SE (1) SE342043B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT289812B (de) * 1968-08-09 1971-05-10 Geigy Ag J R Verfahren zur Herstellung des neuen 2-Methyl-7-chlor-2,3,4,5-tetrahydro-1H-3-benzazepins sowie seiner Säureadditionssalze
DE2016136A1 (de) * 1970-04-04 1971-10-14 C H Boehnnger Sohn, 6507 Ingel heim Neue 7 Acyl 1,2,4,5 tetrahydro (3H) 3 benzazepine
DE2143204C3 (de) * 1971-08-28 1979-09-27 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis
DE2207430C3 (de) * 1972-02-14 1982-05-13 Pennwalt Corp., 19102 Philadelphia, Pa. 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
EP0080779B1 (de) * 1981-11-27 1986-07-16 Smithkline Beckman Corporation 3-Benzazepine als Alpha-2-antagonisten
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
US4973586A (en) * 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
WO1987004430A2 (en) * 1986-01-16 1987-07-30 Schering Corporation Fused benzazepines
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
ATE78467T1 (de) * 1987-07-15 1992-08-15 Schering Corp Kondensierte benzazepine.
WO1991011437A1 (en) * 1990-02-02 1991-08-08 Schering Corporation 4,5-cycloalkano-3-benzazepin-7-ol-derivatives and their use
US6953787B2 (en) 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
US20030220661A1 (en) * 2002-05-21 2003-11-27 Heartstent Corporation Transmyocardial implant delivery system
EP2332919A3 (de) * 2003-06-17 2011-10-19 Arena Pharmaceuticals, Inc. Verfahren zur Herstellung von 3-Benzazepinen
US7704993B2 (en) * 2003-06-17 2010-04-27 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
WO2005042490A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
WO2005042491A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
CN102321023A (zh) 2004-12-21 2012-01-18 艾尼纳制药公司 (r)-8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓盐酸盐的晶型
AU2005322183B2 (en) 2004-12-23 2012-03-29 Arena Pharmaceuticals, Inc. 5HT2C receptor modulator compositions and methods of use
EP2001852A2 (de) 2006-04-03 2008-12-17 Arena Pharmaceuticals, Inc. Verfahren zur herstellung von 8-chlor-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepin und entsprechenden zwischenprodukten
US8299241B2 (en) * 2006-12-05 2012-10-30 Arena Pharmaceuticals, Inc. Processes for preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates thereof
WO2009111004A1 (en) * 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
CN102648170A (zh) 2009-06-18 2012-08-22 艾尼纳制药公司 制备5-ht2c受体激动剂的方法
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
US9045431B2 (en) 2010-06-02 2015-06-02 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
EP3485878A1 (de) 2010-09-01 2019-05-22 Arena Pharmaceuticals, Inc. Darreichungsformen von 5-ht2c-agonisten, die nützlich für gewichtskontrolle sind
US9365521B2 (en) 2010-09-01 2016-06-14 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-HT2C agonists
NZ608266A (en) 2010-09-01 2015-09-25 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
AU2011296014A1 (en) 2010-09-01 2013-04-04 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
JP2015534563A (ja) 2012-10-09 2015-12-03 アリーナ ファーマシューティカルズ， インコーポレイテッド 体重管理の方法

Also Published As

Publication number Publication date
NL6802257A (de) 1968-08-19
CH481110A (de) 1969-11-15
BE710872A (de) 1968-08-16
NO124369B (de) 1972-04-10
FR1560654A (de) 1969-03-21
SE342043B (de) 1972-01-24
IL29485A (en) 1971-07-28
AT275533B (de) 1969-10-27
FR1561479A (de) 1969-03-28
US3652543A (en) 1972-03-28
GB1222397A (en) 1971-02-10
DK115473B (da) 1969-10-13
DE1695124A1 (de) 1970-08-20
DE1668915A1 (de) 1972-03-09
ES350574A1 (es) 1969-11-16
GB1221324A (en) 1971-02-03

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Legal Events

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