EA201390335A1 - Введение лоркасерина индивидуумам с почечной недостаточностью - Google Patents

Введение лоркасерина индивидуумам с почечной недостаточностью

Info

Publication number
EA201390335A1
EA201390335A1 EA201390335A EA201390335A EA201390335A1 EA 201390335 A1 EA201390335 A1 EA 201390335A1 EA 201390335 A EA201390335 A EA 201390335A EA 201390335 A EA201390335 A EA 201390335A EA 201390335 A1 EA201390335 A1 EA 201390335A1
Authority
EA
Eurasian Patent Office
Prior art keywords
individual
renal
sufficiency
level
benzazepine
Prior art date
Application number
EA201390335A
Other languages
English (en)
Inventor
Кристен M. Андерсон
Уилльям Р. Шейнехен
Original Assignee
Арена Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44653552&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201390335(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Арена Фармасьютикалз, Инк. filed Critical Арена Фармасьютикалз, Инк.
Publication of EA201390335A1 publication Critical patent/EA201390335A1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]

Abstract

Настоящее изобретение относится к способам контроля массы у нуждающегося в этом индивидуума посредством определения уровня достаточности почечной функции индивидуума и назначения или введения индивидууму терапевтически эффективного количества (R)-8-хлор-1-метил-2,3,4,5-тетрагидро-1H-3-бензазепина или его фармацевтически приемлемых соли, сольвата или гидрата при условии, что у индивидуума присутствует уровень достаточности почечной функции, выбранный из группы, состоящей из отсутствия почечной недостаточности, слабой почечной недостаточности и умеренной почечной недостаточности. Кроме того, изобретение относится к способу отбора индивидуума для лечения (R)-8-хлор-1-метил-2,3,4,5-тетрагидро-1H-3-бензазепином или его фармацевтически приемлемыми солью, сольватом или гидратом из множества индивидуумов, нуждающихся в контроле массы посредством определения уровня достаточности почечной функции индивидуума и отбора индивидуума для лечения (R)-8-хлор-1-метил-2,3,4,5-тетрагидро-1H-3-бензазепином или его фармацевтически приемлемыми солью, сольватом или гидратом, если у индивидуума присутствует уровень достаточности почечной функции, выбранный из группы, состоящей из отсутствия почечной недостаточности, слабой почечной недостаточности и умеренной почечной недостаточности.
EA201390335A 2010-09-01 2011-08-31 Введение лоркасерина индивидуумам с почечной недостаточностью EA201390335A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40262810P 2010-09-01 2010-09-01
US40314910P 2010-09-10 2010-09-10
PCT/US2011/049936 WO2012030939A1 (en) 2010-09-01 2011-08-31 Administration of lorcaserin to individuals with renal impairment

Publications (1)

Publication Number Publication Date
EA201390335A1 true EA201390335A1 (ru) 2013-09-30

Family

ID=44653552

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201390335A EA201390335A1 (ru) 2010-09-01 2011-08-31 Введение лоркасерина индивидуумам с почечной недостаточностью

Country Status (14)

Country Link
US (3) US8999970B2 (ru)
EP (2) EP2939677A1 (ru)
JP (4) JP2013540719A (ru)
KR (2) KR20180094131A (ru)
CN (1) CN103347523A (ru)
AU (3) AU2011296015B2 (ru)
BR (1) BR112013004707A2 (ru)
CA (1) CA2808890A1 (ru)
EA (1) EA201390335A1 (ru)
HK (1) HK1210419A1 (ru)
MX (1) MX2013002418A (ru)
NZ (2) NZ608266A (ru)
SG (2) SG188365A1 (ru)
WO (1) WO2012030939A1 (ru)

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WO2011153206A1 (en) 2010-06-02 2011-12-08 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
EP2611433A2 (en) * 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
WO2012030953A1 (en) * 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level
SG10201506870PA (en) 2010-09-01 2015-10-29 Arena Pharm Inc Salts of lorcaserin with optically active acids
SG188362A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Modified-release dosage forms of 5-ht2c agonists useful for weight management
US8999970B2 (en) * 2010-09-01 2015-04-07 Arena Pharmaceuticals, Inc. Administration of an anti-obesity compound to individuals with renal impairment
KR20150070249A (ko) 2012-10-09 2015-06-24 아레나 파마슈티칼스, 인크. 체중 관리 방법
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