BR112013011184A2 - composições e métodos para tratamento de mielofibrose - Google Patents

composições e métodos para tratamento de mielofibrose

Info

Publication number
BR112013011184A2
BR112013011184A2 BR112013011184A BR112013011184A BR112013011184A2 BR 112013011184 A2 BR112013011184 A2 BR 112013011184A2 BR 112013011184 A BR112013011184 A BR 112013011184A BR 112013011184 A BR112013011184 A BR 112013011184A BR 112013011184 A2 BR112013011184 A2 BR 112013011184A2
Authority
BR
Brazil
Prior art keywords
methods
compositions
treating myelofibrosis
amino
individual
Prior art date
Application number
BR112013011184A
Other languages
English (en)
Portuguese (pt)
Inventor
Tefferi Ayalew
Jayan Arvind
Cacace Janice
Original Assignee
Targegen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46024747&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013011184(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Targegen Inc filed Critical Targegen Inc
Publication of BR112013011184A2 publication Critical patent/BR112013011184A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112013011184A 2010-11-07 2011-11-07 composições e métodos para tratamento de mielofibrose BR112013011184A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41092410P 2010-11-07 2010-11-07
PCT/US2011/059643 WO2012061833A1 (en) 2010-11-07 2011-11-07 Compositions and methods for treating myelofibrosis

Publications (1)

Publication Number Publication Date
BR112013011184A2 true BR112013011184A2 (pt) 2018-01-30

Family

ID=46024747

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013011184A BR112013011184A2 (pt) 2010-11-07 2011-11-07 composições e métodos para tratamento de mielofibrose

Country Status (36)

Country Link
US (5) US10391094B2 (enExample)
EP (2) EP4159216A1 (enExample)
JP (1) JP6133211B2 (enExample)
KR (4) KR102131241B1 (enExample)
CN (2) CN103282036B (enExample)
AU (2) AU2010363329A1 (enExample)
BR (1) BR112013011184A2 (enExample)
CA (2) CA2816957A1 (enExample)
CL (1) CL2013001252A1 (enExample)
CO (1) CO6801724A2 (enExample)
DK (1) DK2635282T3 (enExample)
DO (1) DOP2013000097A (enExample)
EC (1) ECSP13012658A (enExample)
ES (1) ES2930650T3 (enExample)
HR (1) HRP20221269T1 (enExample)
HU (1) HUE060254T2 (enExample)
IL (1) IL226101A (enExample)
LT (1) LT2635282T (enExample)
MA (1) MA34723B1 (enExample)
MX (2) MX381913B (enExample)
MY (1) MY161164A (enExample)
NI (1) NI201300038A (enExample)
NZ (1) NZ611363A (enExample)
PE (1) PE20140389A1 (enExample)
PH (1) PH12013500924A1 (enExample)
PL (1) PL2635282T3 (enExample)
PT (1) PT2635282T (enExample)
RS (1) RS63996B1 (enExample)
RU (1) RU2616262C2 (enExample)
SG (1) SG190134A1 (enExample)
SI (1) SI2635282T1 (enExample)
SM (1) SMT202200453T1 (enExample)
TW (1) TWI531389B (enExample)
UA (1) UA114076C2 (enExample)
WO (2) WO2012060847A1 (enExample)
ZA (1) ZA201303423B (enExample)

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US8604042B2 (en) 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
WO2012060847A1 (en) * 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
WO2013059548A1 (en) * 2011-10-19 2013-04-25 Sanofi Compositions and methods for treating cancer using jak2 inhibitor
UA114948C2 (uk) * 2013-03-06 2017-08-28 Новартіс Аг Склади з органічними сполуками
CN104771761A (zh) * 2015-03-19 2015-07-15 深圳国源国药有限公司 一种创新药用辅料硅化微晶纤维素及其制备方法
JP6799226B2 (ja) * 2015-07-24 2020-12-16 公立大学法人名古屋市立大学 骨髄線維症の状態の診断を補助する方法、予後の予測を補助する方法、及び治療効果のモニター方法、並びにそれらの方法に用いるマーカー及び装置
CN105919955A (zh) * 2016-06-13 2016-09-07 佛山市腾瑞医药科技有限公司 一种鲁索利替尼制剂及其应用
PL3490582T3 (pl) 2016-07-27 2024-09-23 Acceleron Pharma Inc. Kompozycje do zastosowania w leczeniu mielofibrozy
US11384069B2 (en) 2018-01-16 2022-07-12 Shenzhen Targetrx, Inc. Diphenylaminopyrimidine compound for inhibiting kinase activity
MY209349A (en) 2018-09-25 2025-07-03 Impact Biomedicines Inc Methods of treating myeloproliferative disorders
EP3856189A4 (en) * 2018-09-25 2022-06-29 Impact Biomedicines, Inc. Methods of treating myeloproliferative disorders
KR20210145735A (ko) * 2019-02-12 2021-12-02 임팩트 바이오메디신스, 인코포레이티드 Jak2 저해제의 결정질 형태
FR3092581A1 (fr) * 2019-02-12 2020-08-14 Impact Biomedicines, Inc Formes cristallines d'un inhibiteur de jak2
JP2022549506A (ja) 2019-09-27 2022-11-25 ディスク・メディシン・インコーポレイテッド 骨髄線維症および関連状態を処置するための方法
US11306062B2 (en) 2019-10-29 2022-04-19 Johnson Matthey Public Limited Forms of fedratinib dihydrochloride
KR20220119024A (ko) * 2019-12-20 2022-08-26 인터벳 인터내셔널 비.브이. 피라졸 제약 조성물
WO2021207051A1 (en) * 2020-04-06 2021-10-14 Bristol-Myers Squibb Company Methods of treating acute respiratory disorders
EP4149548A4 (en) 2020-05-13 2024-05-08 Disc Medicine, Inc. ANTI-HEMOJUVELIN ANTIBODIES (HJV) FOR THE TREATMENT OF MYELOFIBROSIS
CA3199509A1 (en) 2020-12-16 2023-06-23 Gopal Krishna Dosing of fedratinib
JP2024507938A (ja) 2021-02-25 2024-02-21 インパクト バイオメディシンズ インコーポレイテッド 骨髄線維症の治療としてのbet阻害剤の使用
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